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Supplements for Weight Gain and Health Management for a 32-Year-Old Male with Existing Conditions

Discussion on supplement recommendations specifically tailored for a 32-year-old male looking to gain weight and enhance appetite, while managing slightly elevated TSH, high cholesterol, and genetic hypertension. Includes advice on Omega-3s, CoQ10, garlic, spirulina, and more.


  • I am 32yo, male, moderately active (walk every day, gym 1-2/week), lightly overweight. I have a slightly elevated TSH but normal levels of free thyroid hormone. I have slightly elevated ratio of bad cholesterol over good one. I have genetic high blood pressure, kept in check with Losartan. I want to gain more weight and stay healthy, recommendations?

  • To support your goals of gaining weight while staying healthy, considering your medical conditions (elevated TSH, high cholesterol, and hypertension), here are some supplement recommendations based on current research:

    1. Fish Oil (Omega-3 fatty acids): Omega-3 is beneficial for cardiovascular health as it can help improve cholesterol levels by lowering triglycerides and increasing HDL (good cholesterol). It also has anti-inflammatory properties that can be helpful in managing hypertension[^1^][^2^].

    2. Coenzyme Q10 (CoQ10): CoQ10 has been noted for its potential benefits in managing blood pressure and improving lipid profiles. It is also essential for cellular energy production, which can support overall health[^3^].

    3. Garlic: Garlic supplements might help in lowering blood pressure and improving cholesterol levels by reducing LDL (bad cholesterol). It also has antioxidative properties[^4^].

    4. Spirulina: Spirulina has been shown to improve blood pressure and lipid profiles while also supporting weight management. It can enhance endothelial function, which is beneficial for cardiovascular health[^5^].

    5. Ginger: Ginger supplementation has been found to help with weight management and improve lipid profiles. It also aids in reducing persistent hypothyroid symptoms, making it particularly relevant for managing slightly elevated TSH levels[^6^].

    It would be best to consult with your healthcare provider before starting any new supplements, especially considering your medical conditions and ongoing medication.

    If you need product recommendations for any of these supplements, please let me know!

  • Which supplements can help me gain weight or get more hungry?

  • If you're looking to gain weight or increase your appetite, several supplements have been shown to be effective for these purposes. Here are some notable options:

    1. Vitamin B Complex: Various B vitamins can help boost appetite and promote weight gain. Studies have shown that vitamin B supplements are associated with an increase in appetite and BMI1.

    2. Fish Oil (Omega-3 fatty acids): Fish oil is known to increase appetite. A study found that fish oil supplementation increased the desire to eat in healthy adults2.

    3. Megestrol Acetate: This is a medication that can stimulate appetite and is often used in medical conditions such as cancer or AIDS-related wasting syndrome. It should be used under medical supervision3.

    4. Iron Supplements: Supplementing with iron can improve appetite, particularly in individuals who are anemic4.

    5. Amino Acid Supplements (HMB, Arginine, and Glutamine): These have been shown to increase muscle protein synthesis and could help in gaining lean body mass5.

    Before starting any new supplement regimen, you should consult with your healthcare provider to tailor the plan to your specific needs and conditions.

    Would you like recommendations for specific products containing these supplements? If so, please let me know which ones you are interested in!

    Footnotes

    1. Mohammad Othman, "Understanding the Impact of Vitamin B Supplements on a Saudi Population," NCBI, 2023.

    2. Signe Damsbo-Svendsen, "Fish oil-supplementation increases appetite in healthy adults. A randomized controlled cross-over trial," PubMed, 2013.

    3. "Megestrol: MedlinePlus Drug Information," MedlinePlus.

    4. J.W. Lawless, "Iron supplementation improves appetite and growth in anemic Kenyan primary school children," PubMed, 1994.

    5. Daniel S. Childs, "A hunger for hunger: A review of palliative therapies for cancer-associated anorexia," NCBI, 2025.

  • Can you share more studies that show that B-vitamin promotes appetite and weight gain and recommend the best product for this purpose?

  • Studies on B-Vitamin Supplements Promoting Appetite and Weight Gain

    1. Vitamin B1 (Thiamin) Deficiency:

      • Study: Association between transient appetite loss and vitamin B1 deficiency in elderly patients with suspected deficiency
      • Summary: This study demonstrated that appetite loss in hospitalized elderly patients could be associated with vitamin B1 deficiency. When B1 deficiency was identified and corrected, there were improvements in appetite1.
    2. B-Vitamin Complex Effects:

      • Study: Understanding the Impact of Vitamin B Supplements on a Saudi Population
      • Summary: A significant proportion of participants experienced increased appetite and BMI after taking vitamin B supplements. This indicates that B vitamins can promote weight gain and improve energy levels2.
    3. Excess Folic Acid:

      • Study: Excess Folic Acid Increases Lipid Storage, Weight Gain, and Adipose Tissue Inflammation in High Fat Diet-Fed Rats
      • Summary: The study showed that excess folic acid intake combined with a high-fat diet exacerbated weight gain and fat accumulation, suggesting that folic acid can have a strong impact on weight gain in certain conditions3.
    4. Vitamin B Complex in Children:

      • Study: APPRAISAL of the use of vitamins B1 and B12 as supplements promoted for the stimulation of growth and appetite in children
      • Summary: This review noted that vitamins B1 and B12 are commonly used to stimulate growth and appetite in children, though it emphasized the need for careful consideration of dosages and individual needs4.

    Product Recommendations for Vitamin B Complex

    Here are some of the top Vitamin B Complex supplements that can help promote appetite and support weight gain:

    Would you like more information about any of these products?

    Footnotes

    1. Ryuichi Ohta, "Association between transient appetite loss and vitamin B1 deficiency in elderly patients with suspected deficiency," NCBI, 2020.

    2. Mohammad Othman, "Understanding the Impact of Vitamin B Supplements on a Saudi Population," NCBI, 2023.

    3. Karen B. Kelly, "Excess Folic Acid Increases Lipid Storage, Weight Gain, and Adipose Tissue Inflammation in High Fat Diet-Fed Rats," NCBI, 2023.

    4. No Authors Listed, "APPRAISAL of the use of vitamins B1 and B12 as supplements promoted for the stimulation of growth and appetite in children," PubMed, 1958.

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