November 2006 Supplement Research Papers

• November 1

  • Absence of efficacy of nonviable Lactobacillus acidophilus for the prevention of traveler's diarrhea: a randomized, double-blind, controlled study.

    • 2006-11-01
    • RCT · n = 348
    • Clinical Infectious Diseases 43(9)
    • • V. Briand
      • P. Buffet
      • S. Genty
      • K. Lacombe
      • N. Godineau
      • J. Salomon
      • Eric Vandemelbrouck
      • P. Ralaimazava
      • C. Goujon
      • S. Matheron
      • A. Fontanet
      • O. Bouchaud

    • PubMed: 17029137
    • DOI: 10.1086/508178

    1 Insight on

    • Reduced Diarrhea Rate

    • High evidence
    • Large Human Trial
    • Rigorous Journal
• Undated – 3 supplement studies

  • Effects of Bifidobacterium lactis Bb12 Supplementation on Intestinal Microbiota of Preterm Infants: a Double-Blind, Placebo-Controlled, Randomized Study

    • 2006-11
    • RCT · n = 69
    • Journal of Clinical Microbiology 44(11)
    • • R. Mohan
      • C. Koebnick
      • J. Schildt
      • S. Schmidt
      • M. Mueller
      • M. Possner
      • M. Radke
      • M. Blaut

    • PubMed: 16971641
    • DOI: 10.1128/JCM.00767-06

    12 Insights on

    • Increased Gut Bifidobacteria
    • Increased Bifidobacteria Levels
    • Reduced Enterobacteriaceae Counts
    • Reduced Clostridium Counts
    • No Reduction in Antibiotic-Resistant Organism Colonization
    • Increased Bifidobacterial Population
    • Reduced Clostridium Species Numbers
    • Reduced Clostridia Counts
    • Reduced Enterobacterial Counts
    • Increased Bifidobacterial Counts
    • Reduced Clostridium Species Counts
    • Increased Bifidobacteria in Colon

    • High evidence
    • Highly Cited

  • Lactobacillus paracasei A survives gastrointestinal passage and affects the fecal microbiota of healthy infants.

    • 2006-11
    • RCT · n = 26
    • Research in Microbiology 157(9)
    • • M. Marzotto
      • C. Maffeis
      • T. Paternoster
      • R. Ferrario
      • L. Rizzotti
      • M. Pellegrino
      • F. Dellaglio
      • S. Torriani

    • PubMed: 16934438
    • DOI: 10.1016/J.RESMIC.2006.06.007

    14 Insights on

    • Improved Gut Microbiota
    • Increased Persistence of Probiotics in Fecal Matter
    • Increased Microbial Diversity
    • Increased Lactobacillus Population
    • Restored Microbial Balance
    • Restored Endogenous Microbiota Equilibrium
    • Temporary Intestinal Dominance of Lactobacillus paracasei A
    • Moderate Impact on Main GI Bacterial Groups
    • Transient Increase in Intestinal Lactobacillus Populations
    • Restoration of Homeostasis
    • Improved Survival Through GI Passage
    • Increased Bifidobacterium Diversity
    • Enhanced Intestinal Lactobacillus Community
    • Moderate Changes in Gastrointestinal Bacterial Groups

    • High evidence

  • Adherence of Lactobacillus crispatus to vaginal epithelial cells from women with or without a history of recurrent urinary tract infection.

    • 2006-11
    • Journal of Urology 176(5)
    • • L. Kwok
      • A. Stapleton
      • W. Stamm
      • S. Hillier
      • Cheryl L. Wobbe
      • K. Gupta

    • PubMed: 17070251
    • DOI: 10.1016/J.JURO.2006.07.014

    3 Insights on

    • Improved Vaginal Epithelial Cell Adherence
    • Reduced Vaginal Colonization of Pathogenic Bacteria
    • Probiotic Adherence Variability Based on Host Factors

    • Low evidence