February 2012 Supplement Research Papers

• February 1

  • Herbal medicines for the management of irritable bowel syndrome: a comprehensive review.

    • 2012-02-01
    • Systematic Review
    • World journal of gastroenterology 18(7)
    • • Roja Rahimi
      • Mohammad Abdollahi

    • PubMed: 22363129
    • DOI: 10.3748/wjg.v18.i7.589

    1 Insight on

    • Improved IBS Symptom Score

    • High evidence

  • Impact of enterococcus on immunocompetent and immunosuppressed patients with perforation of the small or large bowel.

    • 2012-02-01
    • Observational · n = 473
    • Technology and Health Care 20(1)
    • • M. Kaffarnik
      • M. Urban
      • U. Hopt
      • S. Utzolino

    • PubMed: 22297712
    • DOI: 10.3233/THC-2011-0654

    1 Insight on

    • Increased Mortality Rate

    • High evidence
• February 15

  • Effect of a Synbiotic Yogurt on Levels of Fecal Bifidobacteria, Clostridia, and Enterobacteria

    • 2012-02-15
    • RCT · n = 46
    • Applied and Environmental Microbiology 78(4)
    • • Amritanshu Palaria
      • I. Johnson-Kanda
      • D. O'sullivan

    • PubMed: 22101054
    • DOI: 10.1128/AEM.05848-11

    6 Insights on

    • Increased Bifidobacteria Levels
    • Increased Bifidobacterial Population
    • Reduced Clostridium Species Numbers
    • Modulated Gut Microbiota
    • Stable Enterobacterial Numbers
    • Microbial Group Modulation with Bifidobacterial Reduction

    • High evidence
    • Rigorous Journal
• February 17

  • Effect of Lactobacillus salivarius Bacteriocin Abp118 on the Mouse and Pig Intestinal Microbiota

    • 2012-02-17
    • Clinical Trial
    • PLoS ONE 7(2)
    • • Eliette Riboulet-Bisson
      • M. Sturme
      • I. Jeffery
      • M. M. O’Donnell
      • M. M. O’Donnell
      • B. Neville
      • B. Forde
      • M. Claesson
      • H. Harris
      • G. Gardiner
      • P. G. Casey
      • P. Lawlor
      • P. O’Toole
      • R. Ross

    • PubMed: 22363561
    • DOI: 10.1371/journal.pone.0031113

    2 Insights on

    • Altered Spirochaetes Abundance in Pig Microbiota
    • Reduced Impact of Gram-negative Microorganisms

    • Low evidence
    • Highly Cited
    • Animal Study

  • The Obesity and Fatty Liver Are Reduced by Plant-Derived Pediococcus pentosaceus LP28 in High Fat Diet-Induced Obese Mice

    • 2012-02-17
    • RCT · n = 6
    • PLoS ONE 7(2)
    • • Xingrong Zhao
      • Fumiko Higashikawa
      • M. Noda
      • Yusuke Kawamura
      • Y. Matoba
      • T. Kumagai
      • M. Sugiyama

    • PubMed: 22363472
    • DOI: 10.1371/journal.pone.0030696

    3 Insights on

    • Reduced Body Weight
    • Reduced Liver Fat
    • Reduced Abdominal Visceral Fat

    • Low evidence
    • Highly Cited
    • Animal Study
• February 22

  • Histamine Derived from Probiotic Lactobacillus reuteri Suppresses TNF via Modulation of PKA and ERK Signaling

    • 2012-02-22
    • PLoS ONE 7(2)
    • • Carissa M. Thomas
      • T. Hong
      • Jan-Peter van Pijkeren
      • P. Hemarajata
      • D. V. Trinh
      • Weidong Hu
      • R. Britton
      • M. Kalkum
      • J. Versalovic

    • PubMed: 22384111
    • DOI: 10.1371/journal.pone.0031951

    1 Insight on

    • Reduced TNF Production

    • Low evidence
    • Highly Cited

  • Lactobacillus acidophilus Induces Cytokine and Chemokine Production via NF-κB and p38 Mitogen-Activated Protein Kinase Signaling Pathways in Intestinal Epithelial Cells

    • 2012-02-22
    • Clinical and Vaccine Immunology 19(4)
    • • Yujun Jiang
      • Xuena Lü
      • C. Man
      • Linlin Han
      • Yi Shan
      • X. Qu
      • Y. Liu
      • Shiqin Yang
      • Yuqing Xue
      • Yinghua Zhang

    • PubMed: 22357649
    • DOI: 10.1128/CVI.05617-11

    2 Insights on

    • Activated Immune Response
    • Enhanced Cytokine Production

    • Low evidence
• February 28

  • Pregnancy outcome after exposure to the probiotic Lactobacillus in early pregnancy

    • 2012-02-28
    • Observational · n = 304
    • Journal of Obstetrics and Gynaecology 32(3)
    • • J. E. Lee
      • J. .. Han
      • J. Choi
      • H. Ahn
      • S. W. Lee
      • M. H. Kim
      • H. Ryu
      • J. H. Yang
      • A. Nava-Ocampo
      • G. Koren

    • PubMed: 22369393
    • DOI: 10.3109/01443615.2011.641621

    4 Insights on

    • Incidence of Spontaneous Abortions
    • Reduced Preterm Births
    • Reduced Birth Weight
    • Reduced Major Congenital Malformations

    • High evidence
• Undated – 2 supplement studies

  • Lactobacillus fermentum CECT 5716 is safe and well tolerated in infants of 1-6 months of age: a randomized controlled trial.

    • 2012-02
    • RCT
    • Pharmacological Research 65(2)
    • • M. Gil-Campos
      • M. A. López
      • M. V. Rodríguez-Benítez
      • J. Romero
      • I. Roncero
      • Mª Dolores Linares
      • J. Maldonado
      • E. López-Huertas
      • R. Berwind
      • K. Ritzenthaler
      • V. Navas
      • C. Sierra
      • Lluis Sempere
      • A. Geerlings
      • J. Maldonado-Lobón
      • A. Valero
      • F. Lara‐Villoslada
      • M. Olivares

    • PubMed: 22155106
    • DOI: 10.1016/j.phrs.2011.11.016

    7 Insights on

    • Increased Body Weight
    • Reduced Gastrointestinal Infections
    • Reduced Incidence of Gastrointestinal Adverse Events
    • Improved Feeding Tolerance
    • No Significant Difference in Weight Gain
    • Improved Formula Tolerance
    • Reduced Incidence of Gastrointestinal Tract Infection Symptoms

    • High evidence
    • Highly Cited

  • Effect of the oral intake of yogurt containing Bifidobacterium longum BB536 on the cell numbers of enterotoxigenic Bacteroides fragilis in microbiota.

    • 2012-02
    • RCT · n = 420
    • Anaerobe 18(1)
    • • T. Odamaki
      • H. Sugahara
      • S. Yonezawa
      • T. Yaeshima
      • K. Iwatsuki
      • S. Tanabe
      • Tomoya Tominaga
      • H. Togashi
      • Y. Benno
      • J. Xiao

    • PubMed: 22138361
    • DOI: 10.1016/j.anaerobe.2011.11.004

    1 Insight on

    • Reduced Bacteroides Fragilis Group Numbers

    • High evidence
    • Large Human Trial