Effects and mechanisms of probiotics supplement on hypertension.

2026-03-02
Journal of hypertension 44(5)
- Zhe Jiang
- Changlin Zhai
- Chaojie He
- Liang Shen
- Guanmin Tang
- Lijia Xu
- Haojie Yang
- Huilin Hu
- Jungang Han

PubMed: 41766653
DOI: 10.1097/hjh.0000000000004258

Study Design

Type: Review
Population: The global population of individuals suffering from hypertension
Methods: We overview the antihypertensive effects and the potential mechanisms of probiotics supplement on hypertension

The global population of individuals suffering from hypertension is estimated to surpass 1.28 billion. Uncontrolled hypertension makes contributions to the development of cardiovascular and cerebrovascular diseases. Emerging evidence indicates a significant correlation between hypertension and gut microbiota. As an intestinal regulator, which could confer health benefits to the host in adequate amounts, probiotics may become a novel approach to regulating blood pressure without side effects. Therefore, we overview the antihypertensive effects and the potential mechanisms of probiotics supplement on hypertension.

Research Insights

Bifidobacterium animalis subsp. lactis B420→Reduced Blood Pressure
probiotics may become a novel approach to regulating blood pressure without side effects. Therefore, we overview the antihypertensive effects and the potential mechanisms of probiotics supplement on hypertension.
Effect
Beneficial
Effect size
Small
Bifidobacterium lactis B420→Reduced Blood Pressure
probiotics may become a novel approach to regulating blood pressure without side effects. Therefore, we overview the antihypertensive effects and the potential mechanisms of probiotics supplement on hypertension.
Effect
Beneficial
Effect size
Small
Bifidobacterium plantarum→Reduced Blood Pressure
probiotics may become a novel approach to regulating blood pressure without side effects. Therefore, we overview the antihypertensive effects and the potential mechanisms of probiotics supplement on hypertension.
Effect
Beneficial
Effect size
Small
Fermented Soy Probiotic→Reduced Blood Pressure
probiotics may become a novel approach to regulating blood pressure without side effects. Therefore, we overview the antihypertensive effects and the potential mechanisms of probiotics supplement on hypertension.
Effect
Beneficial
Effect size
Small
Lactiplantibacillus plantarum Lp-115→Reduced Blood Pressure
probiotics may become a novel approach to regulating blood pressure without side effects. Therefore, we overview the antihypertensive effects and the potential mechanisms of probiotics supplement on hypertension.
Effect
Beneficial
Effect size
Small
Lactobacillus bulgaricus & Lactobacillus plantarum→Reduced Blood Pressure
probiotics may become a novel approach to regulating blood pressure without side effects. Therefore, we overview the antihypertensive effects and the potential mechanisms of probiotics supplement on hypertension.
Effect
Beneficial
Effect size
Small
Lactobacillus bulgaricus Lb-87→Reduced Blood Pressure
probiotics may become a novel approach to regulating blood pressure without side effects. Therefore, we overview the antihypertensive effects and the potential mechanisms of probiotics supplement on hypertension.
Effect
Beneficial
Effect size
Small
Lactobacillus casei→Reduced Blood Pressure
probiotics may become a novel approach to regulating blood pressure without side effects. Therefore, we overview the antihypertensive effects and the potential mechanisms of probiotics supplement on hypertension.
Effect
Beneficial
Effect size
Small
Lactobacillus casei Lc-11→Reduced Blood Pressure
probiotics may become a novel approach to regulating blood pressure without side effects. Therefore, we overview the antihypertensive effects and the potential mechanisms of probiotics supplement on hypertension.
Effect
Beneficial
Effect size
Small
Lactobacillus fermentum CECT5716→Reduced Blood Pressure
probiotics may become a novel approach to regulating blood pressure without side effects. Therefore, we overview the antihypertensive effects and the potential mechanisms of probiotics supplement on hypertension.
Effect
Beneficial
Effect size
Small
Lactobacillus plantarum LP01→Reduced Blood Pressure
probiotics may become a novel approach to regulating blood pressure without side effects. Therefore, we overview the antihypertensive effects and the potential mechanisms of probiotics supplement on hypertension.
Effect
Beneficial
Effect size
Small
Lactobacillus plantarum Lp-115→Reduced Blood Pressure
probiotics may become a novel approach to regulating blood pressure without side effects. Therefore, we overview the antihypertensive effects and the potential mechanisms of probiotics supplement on hypertension.
Effect
Beneficial
Effect size
Small
Lactobacillus reuteri NCIMB 30242→Reduced Blood Pressure
probiotics may become a novel approach to regulating blood pressure without side effects. Therefore, we overview the antihypertensive effects and the potential mechanisms of probiotics supplement on hypertension.
Effect
Beneficial
Effect size
Small