Lactobacillus salivarius Subspecies salicinius SA-03 is a New Probiotic Capable of Enhancing Exercise Performance and Decreasing Fatigue
- 2020-04-09
- Microorganisms 8(4)
- Mon-Chien Lee
- Y. Hsu
- H. Ho
- Shih‐Hung Hsieh
- Y. Kuo
- Hsin‐Ching Sung
- Chi-Chang Huang
- PubMed: 32283729
- DOI: 10.3390/microorganisms8040545
Abstract
Probiotics are increasingly being used as a nutritional supplement by athletes to improve exercise performance and reduce post-exercise fatigue. Lactobacillus salivarius is a natural flora in the gastrointestinal tract of humans and animals. Lactobacillus salivarius subspecies salicinius (SA-03) is an isolate from the 2008 Olympic women's 48 kg weightlifting gold medalist's gut microbiota. In this study, we investigated its beneficial effects on physical fitness. Male ICR mice were divided into four groups (n = 10 per group) and orally administered with SA-03 for 4 weeks at 0, 2.05 × 109, 4.10 × 109, or 1.03 × 1010 CFU/kg/day. Results showed that 4 weeks of SA-03 supplementation significantly improved muscle strength and endurance performance, increased hepatic and muscular glycogen storage, and decreased lactate, blood urea nitrogen (BUN), ammonia, and creatine kinase (CK) levels after exercise. These observations suggest that SA-03 could be used as a nutritional supplement to enhance exercise performance and reduce.
Keywords: Lactobacillus; SA-03; exercise performance; nutritional supplement; probiotic; weightlifting.
Research Insights
| Supplement | Health Outcome | Effect Type | Effect Size |
|---|---|---|---|
| Lactobacillus Salivarius | Enhanced Glycogen Storage | Beneficial | Large |
| Lactobacillus Salivarius | Improved Exercise Performance | Beneficial | Moderate |
| Lactobacillus Salivarius | Improved Muscle Strength | Beneficial | Moderate |
| Lactobacillus Salivarius | Reduced Ammonia Levels | Beneficial | Moderate |
| Lactobacillus Salivarius | Reduced Blood Urea Nitrogen Levels | Beneficial | Moderate |
| Lactobacillus Salivarius | Reduced Creatine Kinase Levels | Beneficial | Large |
| Lactobacillus salivarius BLIS K12 | Enhanced Glycogen Storage | Beneficial | Large |
| Lactobacillus salivarius BLIS K12 | Improved Exercise Performance | Beneficial | Moderate |
| Lactobacillus salivarius BLIS K12 | Improved Muscle Strength | Beneficial | Moderate |
| Lactobacillus salivarius BLIS K12 | Reduced Ammonia Levels | Beneficial | Moderate |
| Lactobacillus salivarius BLIS K12 | Reduced Blood Urea Nitrogen Levels | Beneficial | Moderate |
| Lactobacillus salivarius BLIS K12 | Reduced Creatine Kinase Levels | Beneficial | Large |
| Lactobacillus salivarius BLIS K12 | Reduced Lactate Levels | Beneficial | Moderate |
| Lactobacillus salivarius HA-118 | Enhanced Glycogen Storage | Beneficial | Large |
| Lactobacillus salivarius HA-118 | Reduced Ammonia Levels | Beneficial | Moderate |
| Lactobacillus salivarius HA-118 | Reduced Blood Urea Nitrogen Levels | Beneficial | Moderate |
| Lactobacillus salivarius HA-118 | Reduced Creatine Kinase Levels | Beneficial | Large |
| Lactobacillus salivarius HA-118 | Reduced Post-Exercise Lactate Levels | Beneficial | Moderate |
| Lactobacillus salivarius SD-5208 | Enhanced Glycogen Storage | Beneficial | Large |
| Lactobacillus salivarius SD-5208 | Improved Exercise Performance | Beneficial | Moderate |
| Lactobacillus salivarius SD-5208 | Improved Muscle Strength | Beneficial | Moderate |
| Lactobacillus salivarius SD-5208 | Reduced Ammonia Levels | Beneficial | Moderate |
| Lactobacillus salivarius SD-5208 | Reduced Blood Urea Nitrogen Levels | Beneficial | Moderate |
| Lactobacillus salivarius SD-5208 | Reduced Creatine Kinase Levels | Beneficial | Large |
| Lactobacillus salivarius SD-5208 | Reduced Lactate Levels | Beneficial | Moderate |
| Lactobacillus salivarius SD-5851 | Enhanced Glycogen Storage | Beneficial | Large |
| Lactobacillus salivarius SD-5851 | Improved Endurance | Beneficial | Large |
| Lactobacillus salivarius SD-5851 | Improved Muscle Strength | Beneficial | Moderate |
| Lactobacillus salivarius SD-5851 | Reduced Ammonia Levels | Beneficial | Moderate |
| Lactobacillus salivarius SD-5851 | Reduced Blood Urea Nitrogen Levels | Beneficial | Moderate |
| Lactobacillus salivarius SD-5851 | Reduced Creatine Kinase Levels | Beneficial | Large |
| Lactobacillus salivarius SD-5851 | Reduced Lactate Levels | Beneficial | Moderate |
| Lactobacillus salivarius UALb-07 | Enhanced Glycogen Storage | Beneficial | Large |
| Lactobacillus salivarius UALb-07 | Improved Exercise Performance | Beneficial | Moderate |
| Lactobacillus salivarius UALb-07 | Improved Muscle Strength | Beneficial | Moderate |
| Lactobacillus salivarius UALb-07 | Increased Hepatic Glycogen Storage | Beneficial | Moderate |
| Lactobacillus salivarius UALb-07 | Reduced Ammonia Levels | Beneficial | Moderate |
| Lactobacillus salivarius UALb-07 | Reduced Blood Urea Nitrogen Levels | Beneficial | Moderate |
| Lactobacillus salivarius UALb-07 | Reduced Creatine Kinase Levels | Beneficial | Large |
| Lactobacillus salivarius UALb-07 | Reduced Lactate Levels | Beneficial | Moderate |
| Lactobacillus salivarius UALs07 | Enhanced Glycogen Storage | Beneficial | Large |
| Lactobacillus salivarius UALs07 | Improved Exercise Performance | Beneficial | Moderate |
| Lactobacillus salivarius UALs07 | Improved Muscle Strength | Beneficial | Moderate |
| Lactobacillus salivarius UALs07 | Reduced Blood Lactate Levels | Beneficial | Moderate |
| Lactobacillus salivarius UALs07 | Reduced Blood Urea Nitrogen Levels | Beneficial | Moderate |
| Lactobacillus salivarius UALs07 | Reduced Creatine Kinase Levels | Beneficial | Large |
| Lactobacillus salivarius UALs07 | Reduced Serum Ammonia Levels | Beneficial | Moderate |
| Lactobacillus salivarius UALs07 UAS | Enhanced Glycogen Storage | Beneficial | Large |
| Lactobacillus salivarius UALs07 UAS | Improved Exercise Performance | Beneficial | Moderate |
| Lactobacillus salivarius UALs07 UAS | Improved Muscle Strength | Beneficial | Moderate |
| Lactobacillus salivarius UALs07 UAS | Reduced Ammonia Levels | Beneficial | Moderate |
| Lactobacillus salivarius UALs07 UAS | Reduced Blood Urea Nitrogen Levels | Beneficial | Moderate |
| Lactobacillus salivarius UALs07 UAS | Reduced Creatine Kinase Levels | Beneficial | Large |
| Lactobacillus salivarius UALs07 UAS | Reduced Lactate Levels | Beneficial | Moderate |
| Lactobacillus salivarius VPro 15 | Reduced Post-Exercise Lactate Levels | Beneficial | Moderate |