rice bran and Reduced Low-Density Lipoprotein Level

Doses used in studies

slices/day: 3–4 (median 3.5, IQR 3–4) — 1 study

Time to effect

Median: 4 weeks · IQR 4 weeks–4 weeks · Range 4 weeks–4 weeks — Reported in 1 of 2 studies

Safety in these studies

Overall tolerabilityReported
No significant differences were observed in the primary outcome, microbial taxa composite within and between groups (False Discovery Rate (FDR) correction, p > 0.10). ... for most of the other outcomes between groups (p > 0.05).
from: Effects of defatted rice bran-fortified bread on gut microbiome, cardiovascular risk, gut

2 of 2 papersPopulation:

Effects of defatted rice bran-fortified bread on gut microbiome, cardiovascular risk, gut discomfort, wellbeing and gut physiology in healthy adults with low dietary fibre intake.
- 2025-06
- RCT · n = 15
- Clinical nutrition ESPEN 67
- - Hwei Min Ng
  - Jasjot Maggo
  - Catherine L Wall
  - Simone B Bayer
  - Jane A Mullaney
  - Diana Cabrera
  - Karl Fraser
  - Janine M Cooney
  - Catrin S Günther
  - Warren C McNabb
  - Meika Foster
  - Chris Frampton
  - Richard B Gearry
  - Nicole C Roy
- PubMed: 40127766
- DOI: 10.1016/j.clnesp.2025.03.045
15 Insights on
- Reduced Low-Density Lipoprotein Level
- High evidence
- Adults
mean total cholesterol (TC) to HDL concentration ratio significantly lowered (p = 0.02) in the DRB group compared to the control group.
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
Three (females) or four (males) slices of DRB-fortified bread daily
The effects of rice bran supplementation for management of blood lipids: A GRADE-assessed systematic review, dose-response meta-analysis, and meta-regression of randomized controlled trials.
- 2023-04-12
- Meta-Analysis
- Systematic reviews 12(1)
- - Zahra Hariri
  - Fatemeh Afzalzade
  - Golbon Sohrab
  - Saeede Saadati
  - Zahra Yari
- PubMed: 37046340
- DOI: 10.1186/s13643-023-02228-y
4 Insights on
- Reduced Low-Density Lipoprotein Level
- High evidence
Meta-analysis of eight RCTs (with 11 effect sizes) showed no significant effect of rice bran supplementation on serum levels of low-density lipoprotein cholesterol (WMD: -1.68 mg/dl; 95% CI: -8.46, 5.09; P = 0.627)
Effect
Neutral
Effect size
Small
Significant
No

rice bran and Reduced Low-Density Lipoprotein Level

Effects of defatted rice bran-fortified bread on gut microbiome, cardiovascular risk, gut discomfort, wellbeing and gut physiology in healthy adults with low dietary fibre intake.

The effects of rice bran supplementation for management of blood lipids: A GRADE-assessed systematic review, dose-response meta-analysis, and meta-regression of randomized controlled trials.