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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Best Supplements for Reduced Plaque Index

Ranked by research evidence. Compare 25 supplements across 33 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.

Top picks by evidence

  • Low evidence3 studies

    Across 3 studies, 2 reported beneficial effects of Lactobacillus reuteri on reducing Plaque Index, with effect sizes ranging from small to moderate; 1 study found no additional benefit over placebo. The median study duration was 180 days (1 study). Populations studied included adolescents with betel quid chewing habits and diabetic adults with periodontitis. The evidence base is small, and findings should be considered preliminary.

    Dose: one lozenge daily to twice a day for 14 days
    Product match
    Primal HarvestPrimal Probiotics
    250,000,000 CFU · $38.95 · ★5.0 (2)
25 supplements
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