Best Supplements for Reduced Plaque Index
Ranked by research evidence. Compare 29 supplements across 42 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Moderate evidence4 studies
Across 4 studies, 3 reported beneficial effects on plaque index, with effect sizes ranging from small to large (mixed). The most robust evidence comes from a 2024 RCT showing a large reduction in plaque index with 0.2% Propolis mouthwash in 45 patients with chronic gingivitis, while a 2023 meta-analysis found no significant effect (p=0.23). The median study duration was 21 days (from one study).
- Low evidence4 studies
Across 4 studies, 3 reported beneficial effects on plaque index, but the highest-quality RCT (evidence score 5) found no effect. The predominant effect size among beneficial studies was mixed (small to large). Evidence is limited by small sample sizes, inconsistent findings, and poorly reported doses.
- ModeratePropolisAcross 4 studies, 3 reported beneficial effects on plaque index, with effect sizes ranging from small to large (mixed). The most robust evidence comes from a 2024 RCT showing a large reduction in plaque index with 0.2% Propolis mouthwash in 45 patients with chronic gingivitis, while a 2023 meta-analysis found no significant effect (p=0.23). The median study duration was 21 days (from one study).3 beneficial1 neutral4 studies
- LowLactobacillus reuteriAcross 4 studies, 3 reported beneficial effects on plaque index, but the highest-quality RCT (evidence score 5) found no effect. The predominant effect size among beneficial studies was mixed (small to large). Evidence is limited by small sample sizes, inconsistent findings, and poorly reported doses.3 beneficial1 neutral4 studies