March 2008 Supplement Research Papers

• March 3

  • Influence of probiotic Lactobacillus acidophilus and L. helveticus on proteolysis, organic acid profiles, and ACE-inhibitory activity of cheddar cheeses ripened at 4, 8, and 12 degrees C.

    • 2008-03-03
    • Journal of Food Science 73(3)
    • • L. Ong
      • N. Shah

    • PubMed: 18387113
    • DOI: 10.1111/j.1750-3841.2008.00689.x

    3 Insights on

    • Increased ACE Inhibitor Activity
    • Increased Organic Acid Levels
    • Improved Proteolysis

    • Low evidence
• March 4

  • Effects of a probiotic Lactobacillus acidophilus strain on feed tolerance in dogs with non-specific dietary sensitivity

    • 2008-03-04
    • RCT · n = 6
    • Archives of Animal Nutrition 62(2)
    • • M. Pascher
      • P. Hellweg
      • A. Khol-Parisini
      • J. Zentek

    • PubMed: 18459535
    • DOI: 10.1080/17450390801892583

    3 Insights on

    • Improved Stool Consistency
    • Reduced Frequency of Defecation
    • Improved Faecal Dry Matter

    • Low evidence
    • Animal Study
• March 11

  • Phase I Trial of a Lactobacillus crispatus Vaginal Suppository for Prevention of Recurrent Urinary Tract Infection in Women

    • 2008-03-11
    • RCT · n = 30
    • Infectious Diseases in Obstetrics and Gynecology 2007
    • • C. Czaja
      • A. Stapleton
      • Yuliya Yarova-Yarovaya
      • W. Stamm

    • PubMed: 18288237
    • DOI: 10.1155/2007/35387

    12 Insights on

    • Reduced Recurrence of Urinary Tract Infections
    • Normalized Vaginal Microbiota
    • Increased Vaginal Lactobacilli Levels
    • Reduced Total Side Effects Incidence
    • Improved Tolerance to Vaginal Suppository
    • Mild Urinary Tract Inflammation
    • Presence of Pyuria
    • Increased Incidence of Pyuria
    • Development of Pyuria
    • Presence of Vaginal Hydrogen Peroxide-Producing Lactobacilli
    • Reduced Urinary Tract Inflammation
    • Improved Tolerability of Lactobacillus crispatus CTV-05

    • High evidence
    • Highly Cited
• Undated – 3 supplement studies

  • Prebiotic evaluation of a novel galactooligosaccharide mixture produced by the enzymatic activity of Bifidobacterium bifidum NCIMB 41171, in healthy humans: a randomized, double-blind, crossover, placebo-controlled intervention study.

    • 2008-03
    • RCT · n = 59
    • The American Journal of Clinical Nutrition 87(3)
    • • F. Dépeint
      • G. Tzortzis
      • J. Vulevic
      • K. I’Anson
      • G. Gibson

    • PubMed: 18326619
    • DOI: 10.1093/AJCN/87.3.785

    2 Insights on

    • Increased Bifidobacterial Population
    • Improved Prebiotic Index

    • High evidence
    • Highly Cited

  • Yogurt Containing Probiotic Lactobacillus rhamnosus GR-1 and L. reuteri RC-14 Helps Resolve Moderate Diarrhea and Increases CD4 Count in HIV/AIDS Patients

    • 2008-03
    • Clinical Trial · n = 24
    • Journal of Clinical Gastroenterology 42(3)
    • • K. Anukam
      • Emanual O Osazuwa
      • H. Osadolor
      • A. Bruce
      • G. Reid

    • PubMed: 18223503
    • DOI: 10.1097/MCG.0b013e31802c7465

    2 Insights on

    • Increased CD4 Counts
    • Resolved Moderate Diarrhea

    • High evidence
    • Highly Cited

  • Saccharomyces boulardii interferes with Shigella pathogenesis by postinvasion signaling events.

    • 2008-03
    • American Journal of Physiology-Gastrointestinal and Liver Physiology 294(3)
    • • K. Mumy
      • Xinhua Chen
      • C. Kelly
      • B. McCormick

    • PubMed: 18032477
    • DOI: 10.1152/AJPGI.00391.2007

    3 Insights on

    • Reduced Inflammatory Response
    • Reduced Baseline IL-8 Secretion
    • Improved Barrier Integrity

    • Low evidence
    • Highly Cited