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Evidence-Based Supplement Research
Evidence-Based Supplement Research
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Lactobacillus acidophilus

Safety profile

4 studies reporting safety data

Across 4 clinical studies, no specific adverse events were quantitatively reported for Lactobacillus acidophilus. The substance was described as well tolerated in multiple studies, with one study noting that patients receiving L. acidophilus had the lowest incidence of adverse events, while another highlighted that rare but serious adverse events (e.g., bacteremia, D-lactic acidosis) have been reported in immunocompromised or critically ill individuals.

Caveats: Limited evidence base; absence of reports does not establish safety. Most data come from studies not primarily designed to assess safety, and findings reflect specific strains used; other formulations may differ.

Most-studied combinations with Lactobacillus acidophilus

most supplement research is combination research
Also studied with:Bifidobacterium lactis (2), Lactobacillus acidophilus La-14 (2), Lactobacillus rhamnosus (2), Lactobacillus salivarius (2), Bifidobacterium bifidum (2), Lactobacillus amylovorus (2), Lactobacillus plantarum (3), bifidobacterium longum (3)
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