June 2011 Supplement Research Papers

• June 1

  • Fermented Milk Containing Bifidobacterium lactis DN-173 010 in Childhood Constipation: A Randomized, Double-Blind, Controlled Trial

    • 2011-06-01
    • RCT · n = 159
    • Pediatrics 127(6)
    • • M. Tabbers
      • A. Chmielewska
      • M. Roseboom
      • N. Crastes
      • C. Perrin
      • J. Reitsma
      • O. Norbruis
      • H. Szajewska
      • M. Benninga

    • PubMed: 21606153
    • DOI: 10.1542/peds.2010-2590

    1 Insight on

    • Increased Stool Frequency

    • High evidence
    • Highly Cited

  • Bifidobacterium breve - HT-29 cell line interaction: modulation of TNF-α induced gene expression.

    • 2011-06-01
    • Beneficial Microbes 2(2)
    • • R. Boesten
      • F. Schuren
      • L. Willemsen
      • A. Vriesema
      • J. Knol
      • W. D. de Vos

    • PubMed: 21831793
    • DOI: 10.3920/BM2011.0005

    2 Insights on

    • Reduced Inflammatory Response
    • Suppressed TNF-α Induced Genes

    • Low evidence
• June 13

  • Dose-response effect of Bifidobacterium lactis HN019 on whole gut transit time and functional gastrointestinal symptoms in adults

    • 2011-06-13
    • RCT · n = 100
    • Scandinavian Journal of Gastroenterology 46(9)
    • • Philip A Waller
      • P. Gopal
      • G. Leyer
      • A. Ouwehand
      • C. Reifer
      • Morgan E Stewart
      • L. Miller

    • PubMed: 21663486
    • DOI: 10.3109/00365521.2011.584895

    8 Insights on

    • Well-Tolerated Supplementation
    • No Adverse Events Observed
    • Absence of Adverse Events
    • Reduced Whole Gut Transit Time
    • Reduced Frequency of Functional Gastrointestinal Symptoms
    • Improved Supplement Tolerance
    • Improved Whole Gut Transit Time
    • Reduced Functional Gastrointestinal Symptom Frequency

    • High evidence
    • Highly Cited
• June 14

  • Efficacy of turmeric (curcumin) in pain and postoperative fatigue after laparoscopic cholecystectomy: a double-blind, randomized placebo-controlled study

    • 2011-06-14
    • RCT · n = 50
    • Surgical Endoscopy 25(12)
    • • K. Agarwal
      • C. D. Tripathi
      • B. Agarwal
      • S. Saluja

    • PubMed: 21671126
    • DOI: 10.1007/s00464-011-1793-z

    3 Insights on

    • Reduced Analgesic Usage
    • Reduced Postoperative Pain
    • Reduced Postoperative Fatigue

    • High evidence
    • Highly Cited
• June 17

  • Functional Analysis of the p40 and p75 Proteins from Lactobacillus casei BL23

    • 2011-06-17
    • Microbial Physiology 19(4)
    • • Christine Bäuerl
      • G. Pérez-Martínez
      • Fang Yan
      • D. Polk
      • V. Monedero

    • PubMed: 21178363
    • DOI: 10.1159/000322233

    1 Insight on

    • Enhanced Intestinal Mucosal Cell Protection

    • Low evidence
    • Highly Cited
• June 19

  • The immunomodulatory properties of viable Lactobacillus salivarius ssp. salivarius CECT5713 are not restricted to the large intestine

    • 2011-06-19
    • Clinical Trial
    • European Journal of Nutrition 51(3)
    • • B. Arribas
      • N. Garrido-Mesa
      • Laura Perán
      • D. Camuesco
      • M. Comalada
      • E. Bailón
      • M. Olivares
      • J. Xaus
      • L. Kruidenier
      • I. Sanderson
      • A. Zarzuelo
      • M. Rodríguez-Cabezas
      • J. Gálvez

    • PubMed: 21688122
    • DOI: 10.1007/s00394-011-0221-4

    7 Insights on

    • Reduced Inflammation Levels
    • Reduced IL-8 Production
    • Reduced TNF Production
    • Improved Intestinal Epithelium Recovery
    • Increased Hepatic Glutathione Content
    • Improved T-Cell Cytokine Production
    • Reduced Plasma IgG Production

    • Low evidence
    • Rigorous Journal
    • Animal Study
• Undated – 1 supplement study

  • Lactobacillus johnsonii N6.2 stimulates the innate immune response through Toll-like receptor 9 in Caco-2 cells and increases intestinal crypt Paneth cell number in biobreeding diabetes-prone rats.

    • 2011-06
    • Clinical Trial
    • The Journal of Nutrition 141(6)
    • • S. Kingma
      • Nan Li
      • F. Sun
      • Ricardo B. Valladares
      • J. Neu
      • G. Lorca

    • PubMed: 21490291
    • DOI: 10.3945/jn.110.135517

    2 Insights on

    • Enhanced Innate Immune Response
    • Increased Paneth Cell Number in Intestinal Crypts

    • Low evidence
    • Highly Cited
    • Animal Study