Osteoarthritis
Osteoarthritis (OA) is a degenerative joint disease characterized by the breakdown of joint cartilage and underlying bone, leading to symptoms like joint pain, stiffness, swelling, and decreased range of motion, most commonly affecting the fingers, thumbs, knees, hips, neck, and lower back. Risk factors include joint injury, obesity, aging, misaligned joints, and family history, with symptoms typically progressing slowly and potentially interfering with daily activities.
Health Outcomes
- Activated Wnt/Beta-Catenin Signaling
- Alleviated Clinical Outcomes
- Beneficial Clinical Effects
- Changed Leukocyte Telomere Length
- Changed Mechanical Pain Sensitivity
- Changed Pressure Pain Threshold
- Changed Walking Cadence
- Decreased Vastus Medialis Thickness
- Delayed Time to First Analgesic Request
- Duration of Symptoms
- Elevated Serum Substance P Levels
- Enhanced Anti-inflammatory Properties
- Enhanced Anti-inflammatory Response
- Enhanced Antioxidant Enzyme Activity
- Enhanced Cell Viability Under Oxidative Stress
- Enhanced Inflammation Resolution
- Enhanced Inflammatory Response
- Improved 6-Meter Walk Performance
- Improved Activities of Daily Living
- Improved Activities of Daily Living Score
- Improved Agility
- Improved Agility Performance
- Improved Aging Symptom
- Improved Aging-Related Changes
- Improved Antioxidant and Anti-Inflammatory Response
- Improved Balance
- Improved Barthel Index Score
- Improved Berg Balance Scale
- Improved Bone Health
- Improved Chair Rise Performance
- Improved Chair Stand
- Improved Clinical Effective Rate
- Improved Daily Activity Participation
- Improved Disability Score
- Improved Distance Traveled
- Improved Ease of Use
- Improved Exercise Function
- Improved Five Times Sit-to-Stand Time
- Improved Flexed Arm Range of Motion
- Improved Flexibility
- Improved Function
- Improved Function Score
- Improved Functional Activity
- Improved Functional Ambulation Classification
- Improved Functional Outcome
- Improved Functional Recovery
- Improved Functional Status
- Improved Gait Speed
- Improved General Health Perception
- Improved Global Quality of Life
- Improved Global Symptom
- Improved Harris Hip Score
- Improved Health in Elderly Populations
- Improved Hip Joint Motion
- Improved Isokinetic Strength
- Improved JOA Score
- Improved Joint Function
- Improved Joint Pain
- Improved Jump Height
- Improved KOA Symptoms
- Improved Knee Extensor Peak Torque
- Improved Knee Extensor Strength
- Improved Knee Flexor Peak Torque
- Improved Knee Joint Extensor Strength
- Improved Knee Muscle Strength
- Improved Knee Society Score
- Improved Leg Extension Strength
- Improved Leg Press Performance
- Improved Leg Press Strength
- Improved Leg Strength
- Improved Lower Body Endurance
- Improved Lower Body Muscular Endurance
- Improved Lower Body Power
- Improved Lower Body Strength
- Improved Lower Limb Maximal Neuromuscular Performance
- Improved Lower Limb Peak Power
- Improved Lower-Body Strength and Power
- Improved Maximal Power
- Improved Maximal Walking Performance
- Improved Mechanical Properties
- Improved Mobility
- Improved Mobility Score
- Improved Mouth Opening Limitation
- Improved Musculoskeletal Disease Symptom
- Improved One Repetition Maximum Squat
- Improved Orthopedic Function
- Improved Osseointegration
- Improved Osteoarthritis
- Improved Osteoarthritis Symptoms
- Improved Oswestry Disability Index Score
- Improved Overall Health
- Improved Overall Symptom Relief
- Improved Pain
- Improved Pain Intensity
- Improved Pain Management
- Improved Pain Scale
- Improved Pain Score
- Improved Pain Severity
- Improved Pain Threshold
- Improved Patient Global Assessment
- Improved Patient Global Impression of Change (PGI-C) Scores
- Improved Patient Satisfaction
- Improved Patient-Reported Outcome
- Improved Perceived Health Status
- Improved Physical Activity Initiation
- Improved Physical Domain Score
- Improved Physical Function
- Improved Physical Health
- Improved Physical Health-Related Quality of Life
- Improved Physical Mobility
- Improved Physical Performance
- Improved Physical Quality of Life
- Improved Physical Role Limitation
- Improved Physician Global Assessment
- Improved Presenteeism
- Improved Pressure Pain Threshold
- Improved Quadriceps Contraction Strength
- Improved Quadriceps Endurance
- Improved Quadriceps Function
- Improved Quadriceps Strength
- Improved Quality of Life Score
- Improved Radial Inclination
- Improved Radiographic Success
- Improved Range of Motion
- Improved Role Physical
- Improved Role Physical Health
- Improved Self-assessed Disability
- Improved Serum Hyaluronan Levels
- Improved Sit-to-Stand Test Performance
- Improved Specific Elements Within Assessed Measures
- Improved Standing Balance
- Improved Stiffness
- Improved Strain Index
- Improved Structure-Function Relationship
- Improved Symptom Control in Degenerative Joint Disease
- Improved Symptom Relief
- Improved Symptom Severity
- Improved Symptoms
- Improved Throwing Performance
- Improved Timed Up and Go
- Improved Timed Up and Go Performance
- Improved Timed Up and Go Test
- Improved Timed Up-and-Go Test Performance
- Improved Tissue Inhibitor of Matrix Metalloproteinase-1 Level
- Improved Tolerance
- Improved Ulnar Variance
- Improved Vertical Jump Performance
- Improved WOMAC Score
- Improved Walking Ability
- Improved Walking Distance
- Improved Walking Speed
- Improved Wall-Squat Performance
- Improved Wall-Squat Time
- Improved Western Ontario and McMaster Universities Osteoarthritis Index Total Score
- Increase in Persistent Diseased Sites
- Increased Analgesic Capacity
- Increased Anti-inflammatory Cytokines
- Increased Antioxidant Activity
- Increased Benefit Rate
- Increased Body Mass Index
- Increased Body Weight
- Increased Bone Density
- Increased Bone Formation/Resorption Ratio
- Increased Collagen Synthesis
- Increased EGF Level
- Increased Femoral Neck Bone Mineral Density
- Increased Hyaluronic Acid Molecular Weight
- Increased Hyaluronic Acid Production
- Increased Interleukin-1 Beta Production
- Increased Knee Extension Strength
- Increased Knee Flexion
- Increased MicroRNA-146a Expression
- Increased Mineralized Matrix Deposition
- Increased Muscle Cross-Sectional Area
- Increased Nerve Growth Factor Receptor Level
- Increased Number of Pain-free Days
- Increased Osteoprotegerin Immunostaining
- Increased PTGS2 Expression
- Increased Pain
- Increased Pain-Free Days
- Increased Patellar Tendon Cross-Sectional Area
- Increased Perceived Pain
- Increased Physical Activity
- Increased Plasma Vitamin K Levels
- Increased Quadriceps Contraction Strength
- Increased Tibial Cross-sectional Area
- Increased Trabecular Thickness
- Increased Walking Speed
- Maintained Morphological Integrity
- Maintained Physical Activity Level
- Maintained Physical Performance
- Maintained Vigorous Locomotion
- Modulated Nociceptive Signaling
- No Clear Clinical Benefit
- No Clear Effect on Systemic Inflammation
- No Conclusive Efficacy
- No Conclusive Long-Term Clinical Benefit
- No Difference in Adverse Events
- No Significant Change in Hip Joint Bone Mineral Density
- No Significant Change in Tumor Necrosis Factor Alpha Levels
- Normalized Serum IL-1β Levels
- Reduced 10-meter Walk Test Time
- Reduced Aging-related Changes
- Reduced Analgesic Consumption
- Reduced Analgesic Usage
- Reduced Analgesic Use
- Reduced Arthralgia
- Reduced Arthritis Incidence
- Reduced Arthritis Score
- Reduced Arthritis Severity
- Reduced Arthritis Symptoms
- Reduced Average Pain
- Reduced Bodily Pain
- Reduced COX-2 Levels
- Reduced Cadence
- Reduced Cellular Senescence
- Reduced Clinical Symptoms of Arthritis
- Reduced Collagen Secretion
- Reduced Conditioned Pain Modulation
- Reduced Cyclooxygenase-2 Levels
- Reduced Disability
- Reduced Discomfort
- Reduced Exercise-Induced Inflammation
- Reduced General Discomfort
- Reduced Hand Pain
- Reduced Hyaluronan Level
- Reduced Hyaluronidase Activity
- Reduced IL-1β Levels
- Reduced Impediment
- Reduced Inflammatory Pathways
- Reduced Interference Score
- Reduced Interference with Daily Life
- Reduced Interleukin-1β Levels
- Reduced Interleukin-6 Levels
- Reduced Intestinal Adenoma Incidence
- Reduced Joint Damage
- Reduced Joint Inflammation
- Reduced Joint Stiffness
- Reduced Joint Swelling
- Reduced Joint Tenderness
- Reduced Knee Pain
- Reduced Knee Pain at Rest
- Reduced Locomotor Impairment
- Reduced Matrix Metalloproteinase-1 Level
- Reduced Mean Total Severity per Day in Reported Episodes
- Reduced Morphine Consumption
- Reduced Muscle Joint Pain
- Reduced Musculoskeletal Dysfunction
- Reduced Musculoskeletal Pain
- Reduced Need for Rescue Analgesia
- Reduced Nuclear Factor-κB Level
- Reduced Number of Painful Joints
- Reduced Opioid Consumption
- Reduced Overall Symptom Score
- Reduced Oxycodone Usage
- Reduced Pain
- Reduced Pain Assessment Score
- Reduced Pain During Activity
- Reduced Pain During Movement
- Reduced Pain Frequency
- Reduced Pain Intensity
- Reduced Pain Levels
- Reduced Pain Medication Use
- Reduced Pain Relief Time
- Reduced Pain Scale
- Reduced Pain Sensitivity
- Reduced Pain Severity
- Reduced Pain Symptom Score
- Reduced Pain Symptoms
- Reduced Pain at Rest
- Reduced Pain-Related Disability
- Reduced Painkiller Consumption
- Reduced Paw Volume
- Reduced Perioperative Morphine Use
- Reduced Physical Activity
- Reduced Physical Disability
- Reduced Physical Symptoms
- Reduced Postoperative Analgesic Requirement
- Reduced Postoperative Complications
- Reduced Postoperative Fatigue
- Reduced Postoperative Pain
- Reduced Postoperative Pain Intensity
- Reduced Postoperative Pain Score
- Reduced Proinflammatory Mediators
- Reduced Quadriceps Muscle Cross-Sectional Area
- Reduced Redness at Surgical Site
- Reduced Release of Inflammatory Mediators (TNF-α, IL-6, IL-1β, IL-10)
- Reduced Senescence-Associated Beta-Galactosidase Activity
- Reduced Senescence-Associated Secretory Phenotype
- Reduced Serum Collagen Type II C-Telopeptide (sCTX-II)
- Reduced Shoulder Stiffness
- Reduced Soreness
- Reduced Standard Care Medication Need
- Reduced Stiffness
- Reduced Substance P Levels
- Reduced Surface Skewness
- Reduced Swelling
- Reduced Swimming Time
- Reduced Symptom Severity Scale Score
- Reduced Synovitis Score
- Reduced TCM Syndrome Score
- Reduced TRPV1 Activation
- Reduced Time to Pain Cessation
- Reduced Timed Up and Go Test Time
- Reduced Tissue Inhibitor of Metalloproteinase 1 Level
- Reduced Total Analgesic Dosage
- Reduced Total Morphine Consumption
- Reduced Treatment Costs
- Reduced Use of Pain Relieving Drugs
- Reduced Visual Analog Scale Score
- Reduced WOMAC Function Score
- Reduced WOMAC Pain Score
- Reduced Walking Time
- Reduced Worst Pain
- Relieved Joint Pain
- Slowed Progression of Knee Osteoarthritis
- Strengthened Musculoskeletal System
- Supported Physiological Function in Elderly
- Unchanged Biochemical Parameters
- Unchanged Symptom Severity
- Upregulated Macrophage Inhibitory Factor
- Well-Tolerated Supplementation