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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Best Supplements for Improved Gut Microbiome Composition

Ranked by research evidence. Compare 27 supplements across 36 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.

Top picks by evidence

  • Low evidence4 studies

    Across 3 studies, all reported beneficial effects on gut microbiome composition, with effect sizes ranging from moderate to large. The evidence is preliminary (only 3 studies, none reported statistical significance). The highest-quality study (RCT in 120 GERD patients) found moderate beneficial effects via metagenomic remodeling. No consistent dose or study duration data were reported.

    Product match
    California Gold NutritionLactoBif 100 Probiotics
    · $32.35 · ★4.7 (17,687)
27 supplements
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