June 2012 Supplement Research Papers

• June 1

  • Oral consumption of potential probiotic Saccharomyces boulardii strain Unique 28 in patients with acute diarrhoea: a clinical report.

    • 2012-06-01
    • Clinical Trial · n = 25
    • Beneficial Microbes 3(2)
    • • M. Sudha
      • S. Bhonagiri
      • M. Asin Kumar

    • PubMed: 22476321
    • DOI: 10.3920/BM2011.0055

    5 Insights on

    • Improved Stool Consistency
    • Reduced Duration of Diarrhea
    • Reduced Abdominal Pain
    • No Significant Safety Parameter Changes
    • Reduced Frequency of Defecation

    • Moderate evidence
• June 13

  • Probiotic effects of orally administered Lactobacillus reuteri-containing tablets on the subgingival and salivary microbiota in patients with gingivitis. A randomized clinical trial.

    • 2012-06-13
    • RCT · n = 40
    • Journal of Clinical Periodontology 39(8)
    • • M. Iniesta
      • D. Herrera
      • E. Montero
      • M. Zurbriggen
      • A. R. Matos
      • M. Marín
      • M. Sánchez-Beltrán
      • Arancha Llama-Palacio
      • M. Sanz

    • PubMed: 22694350
    • DOI: 10.1111/j.1600-051X.2012.01914.x

    5 Insights on

    • Reduced Anaerobic Bacteria in Saliva
    • Reduced Prevotella intermedia Concentration in Saliva
    • Reduced Subgingival Porphyromonas gingivalis Levels
    • Reduced Periodontal Pathogens
    • Reduced Oral Anaerobic Bacterial Counts

    • High evidence
    • Highly Cited

  • Milk containing probiotic Lactobacillus rhamnosus GG and respiratory illness in children: a randomized, double-blind, placebo-controlled trial

    • 2012-06-13
    • RCT · n = 523
    • European Journal of Clinical Nutrition 66(9)
    • • M. Kumpu
      • R. Kekkonen
      • Hannu J. Kautiainen
      • S. Järvenpää
      • A. Kristo
      • P. Huovinen
      • A. Pitkäranta
      • R. Korpela
      • K. Hatakka

    • PubMed: 22692023
    • DOI: 10.1038/ejcn.2012.62

    2 Insights on

    • Reduced Respiratory Illness
    • Reduced Incidence of Respiratory Illness

    • High evidence
    • Large Human Trial
    • Highly Cited
    • Rigorous Journal
• June 15

  • A protective effect of Lactobacillus rhamnosus HN001 against eczema in the first 2 years of life persists to age 4 years

    • 2012-06-15
    • RCT
    • Clinical & Experimental Allergy 42(7)
    • • K. Wickens
      • Peter N. Black
      • Thorsten Stanley
      • Edwin A. Mitchell
      • C. Barthow
      • P. Fitzharris
      • Gordon Purdie
      • Julian Crane

    • PubMed: 22702506
    • DOI: 10.1111/j.1365-2222.2012.03975.x

    6 Insights on

    • Reduced Eczema Prevalence
    • Reduced Prevalence of Atopic Sensitization
    • Reduced Wheeze Prevalence
    • Reduced SCORAD Score
    • Reduced Eczema
    • Reduced Prevalence of Rhinoconjunctivitis

    • High evidence
    • Highly Cited
• June 21

  • Lactobacillus plantarum ZLP001: In vitro Assessment of Antioxidant Capacity and Effect on Growth Performance and Antioxidant Status in Weaning Piglets

    • 2012-06-21
    • RCT · n = 96
    • Asian-Australasian Journal of Animal Sciences 25(8)
    • • J. Wang
      • H. Ji
      • S. Wang
      • D. Zhang
      • H. Liu
      • D. Shan
      • Y. M. Wang

    • PubMed: 25049675
    • DOI: 10.5713/ajas.2012.12079

    7 Insights on

    • Reduced Hepatic Oxidative Stress
    • Improved Growth Performance
    • Reduced Serum Malondialdehyde Levels
    • Improved Antioxidant Enzyme Levels
    • Increased Glutathione Peroxidase Activity
    • Increased Superoxide Dismutase Levels
    • Increased Catalase Levels

    • Low evidence
    • Animal Study
• Undated – 5 supplement studies

  • Hilyses®, fermented Saccharomyces cerevisiae, enhances the growth performance and skin non-specific immune parameters in rainbow trout (Oncorhynchus mykiss).

    • 2012-06
    • RCT
    • Fish & Shellfish Immunology 32(6)
    • • N. Sheikhzadeh
      • M. Heidarieh
      • A. K. Pashaki
      • K. Nofouzi
      • Marjan Ahrab Farshbafi
      • M. Akbari

    • PubMed: 22440584
    • DOI: 10.1016/j.fsi.2012.03.003

    3 Insights on

    • Improved Antibacterial Activity
    • Improved Growth Performance
    • Increased Mucus Enzyme Activities in Skin

    • High evidence
    • Highly Cited

  • Evaluation of safety and tolerance of microencapsulated Lactobacillus reuteri NCIMB 30242 in a yogurt formulation: a randomized, placebo-controlled, double-blind study.

    • 2012-06
    • RCT · n = 120
    • Food and Chemical Toxicology 50(6)
    • • M. Jones
      • C. Martoni
      • S. Tamber
      • Mathieu Parent
      • S. Prakash

    • PubMed: 22425689
    • DOI: 10.1016/j.fct.2012.03.010

    2 Insights on

    • Stable Fecal Deconjugated Bile Acid Levels
    • Safe Use of Lactobacillus reuteri NCIMB 30242

    • High evidence

  • Clinical Saccharomyces cerevisiae isolates cannot cross the epithelial barrier in vitro.

    • 2012-06
    • International Journal of Food Microbiology 157(1)
    • • R. Pérez-Torrado
      • S. Llopis
      • L. Jespersen
      • Teresa Fernández-Espinar
      • A. Querol

    • PubMed: 22609000
    • DOI: 10.1016/j.ijfoodmicro.2012.04.012

    2 Insights on

    • Impaired Intestinal Barrier Function
    • Increased Risk of Opportunistic Infection due to Compromised Epithelial Barrier

    • Low evidence

  • Genome Sequence of Lactobacillus salivarius SMXD51, a Potential Probiotic Strain Isolated from Chicken Cecum, Showing Anti-Campylobacter Activity

    • 2012-06
    • Journal of Bacteriology 194(11)
    • • Gilles Kergourlay
      • Soumaya Messaoudi
      • X. Dousset
      • H. Prévost

    • PubMed: 22582370
    • DOI: 10.1128/JB.00344-12

    1 Insight on

    • Reduced Campylobacter Infection

    • Low evidence

  • In vitro and in vivo characterization and strain safety of Lactobacillus reuteri NCIMB 30253 for probiotic applications.

    • 2012-06
    • Canadian Journal of Microbiology 58(6)
    • • I. Sulemankhil
      • Mathieu Parent
      • M. Jones
      • Zhenqiang Feng
      • A. Labbé
      • S. Prakash

    • PubMed: 22642667
    • DOI: 10.1139/w2012-050

    1 Insight on

    • Reduced Pro-inflammatory Cytokine Interleukin-8 Levels

    • Low evidence