June 2013 Supplement Research Papers

• June 1

  • Influence of the probiotic Streptococcus salivarius strain M18 on indices of dental health in children: a randomized double-blind, placebo-controlled trial.

    • 2013-06-01
    • RCT · n = 100
    • Journal of Medical Microbiology 62(6)
    • • J. Burton
      • B. Drummond
      • C. Chilcott
      • J. Tagg
      • W. Thomson
      • J. Hale
      • P. Wescombe

    • PubMed: 23449874
    • DOI: 10.1099/jmm.0.056663-0

    6 Insights on

    • Reduced Mutans Streptococcus Counts
    • Reduced Plaque Score
    • No Significant Adverse Events
    • Reduced Formation of Dental Plaque
    • Improved Oral Health
    • Maintained Soft-Tissue Health

    • High evidence
    • Highly Cited

  • Efficacy of Bacillus clausii strain UBBC-07 in the treatment of patients suffering from acute diarrhoea.

    • 2013-06-01
    • Beneficial Microbes 4(2)
    • • M. Sudha
      • S. Bhonagiri
      • M. Asin Kumar

    • PubMed: 23443952
    • DOI: 10.3920/BM2012.0034

    8 Insights on

    • Improved Stool Consistency
    • Reduced Duration of Diarrhea
    • Reduced Abdominal Pain Severity
    • Reduced Abdominal Pain
    • Absence of Adverse Effects
    • No Significant Adverse Events
    • No Adverse Health Effects
    • Reduced Frequency of Defecation

    • Low evidence
• June 13

  • Persistence of the Oral Probiotic Streptococcus salivarius M18 Is Dose Dependent and Megaplasmid Transfer Can Augment Their Bacteriocin Production and Adhesion Characteristics

    • 2013-06-13
    • Clinical Trial · n = 75
    • PLoS ONE 8(6)
    • • J. Burton
      • P. Wescombe
      • Jean M. Macklaim
      • M. Chai
      • K. Macdonald
      • J. Hale
      • J. Tagg
      • G. Reid
      • G. Gloor
      • P. Cadieux

    • PubMed: 23785463
    • DOI: 10.1371/journal.pone.0065991

    7 Insights on

    • Reduced Harmful Gut Bacteria
    • Reduced Oral Cavity Persistence
    • Improved Antimicrobial Production
    • Increased Antimicrobial Resistance
    • Modulated Bacterial Phenotypes
    • Improved Adhesion Characteristics
    • Reduced Impact on Existing Indigenous Microbiota

    • High evidence
    • Highly Cited
    • Rigorous Journal
• June 19

  • Effects of Bacillus subtilis natto on milk production, rumen fermentation and ruminal microbiome of dairy cows.

    • 2013-06-19
    • RCT · n = 36
    • Animal 7(2)
    • • P. Sun
      • J. Q. Wang
      • L. F. Deng

    • PubMed: 23031615
    • DOI: 10.1017/S1751731112001188

    8 Insights on

    • Reduced Acetate to Propionate Ratio
    • Reduced Somatic Cell Count
    • Improved Milk Composition
    • Increased Milk Production
    • Enhanced Milk Production
    • Reduced NDF Digestibility
    • Improved Milk Protein Yield
    • Increased Lactose Yield in Milk

    • Low evidence
    • Highly Cited
    • Rigorous Journal
    • Animal Study
• Undated – 3 supplement studies

  • Consumption of fermented milk product with probiotic modulates brain activity.

    • 2013-06
    • RCT · n = 36
    • Gastroenterology 144(7)
    • • K. Tillisch
      • J. Labus
      • L. Kilpatrick
      • Zhiguo Jiang
      • J. Stains
      • Bahar Ebrat
      • D. Guyonnet
      • S. Legrain-Raspaud
      • Beatrice Trotin
      • B. Naliboff
      • E. Mayer

    • PubMed: 23474283
    • DOI: 10.1053/j.gastro.2013.02.043

    2 Insights on

    • Reduced Negative Emotional Responses
    • Improved Brain Activity

    • High evidence
    • Highly Cited

  • Evaluation of adhesion properties and antibacterial activities of the infant gut commensal Bifidobacterium bifidum PRL2010.

    • 2013-06
    • Anaerobe 21
    • • Fausta Serafini
      • F. Strati
      • P. Ruas-Madiedo
      • F. Turroni
      • Elena Foroni
      • S. Duranti
      • F. Milano
      • Alessio Perotti
      • Alice Viappiani
      • S. Guglielmetti
      • A. Buschini
      • A. Margolles
      • D. van Sinderen
      • M. Ventura

    • PubMed: 23523946
    • DOI: 10.1016/j.anaerobe.2013.03.003

    3 Insights on

    • Reduced Pathogen Adhesion
    • Enhanced Adherence to Intestinal Epithelial Cells
    • Improved Survival Under Gastrointestinal Challenges

    • Low evidence

  • Orally administered LPS enhances head kidney macrophage activation with down-regulation of IL-6 in common carp (Cyprinus carpio).

    • 2013-06
    • Clinical Trial
    • Fish & Shellfish Immunology 34(6)
    • • T. Kadowaki
      • Y. Yasui
      • Osamu Nishimiya
      • Y. Takahashi
      • C. Kohchi
      • G. Soma
      • H. Inagawa

    • PubMed: 23567856
    • DOI: 10.1016/j.fsi.2013.03.372

    1 Insight on

    • Reduced Interleukin-6 Production

    • Low evidence
    • Animal Study