May 2014 Supplement Research Papers

• May 1

  • In vitro and in vivo effects of beneficial vaginal lactobacilli on pathogens responsible for urogenital tract infections.

    • 2014-05-01
    • Clinical Trial
    • Journal of Medical Microbiology 63(5)
    • • P. R. De Gregorio
      • M. S. Juárez Tomás
      • M. C. Leccese Terraf
      • M. Nader-Macías

    • PubMed: 24523160
    • DOI: 10.1099/jmm.0.069401-0

    7 Insights on

    • Reduced Pathogen Growth
    • Improved Antimicrobial Ability
    • Increased Bacterial Aggregation
    • Preventive Effect Against Streptococcus agalactiae Infection
    • Reduced Streptococcus agalactiae Growth
    • Increased Aggregation of Streptococcus agalactiae
    • No Reduction in Streptococcus agalactiae

    • Low evidence
    • Animal Study
• May 13

  • The efficacy of Lactobacillus reuteri DSM 17938 in infants and children: a review of the current evidence

    • 2014-05-13
    • Systematic Review
    • European Journal of Pediatrics 173(10)
    • • M. Urbańska
      • H. Szajewska

    • PubMed: 24819885
    • DOI: 10.1007/s00431-014-2328-0

    6 Insights on

    • Reduced Diarrhea Incidence
    • Reduced Crying Time in Infants with Colic
    • Reduced Nosocomial Diarrhea Incidence
    • Improved Functional Constipation
    • Improved Management of Acute Gastroenteritis
    • Reduced Diarrhea Incidence in Day Care Centers

    • High evidence
    • Highly Cited
• May 15

  • Enterococcus faecalis from Healthy Infants Modulates Inflammation through MAPK Signaling Pathways

    • 2014-05-15
    • PLoS ONE 9(5)
    • • Shugui Wang
      • M. Hibberd
      • S. Pettersson
      • Yuan-Kun Lee

    • PubMed: 24830946
    • DOI: 10.1371/journal.pone.0097523

    2 Insights on

    • Reduced Inflammation
    • Reduced Proinflammatory Cytokine Secretion

    • Moderate evidence
    • Highly Cited
    • Rigorous Journal
• May 22

  • The HMI™ module: a new tool to study the Host-Microbiota Interaction in the human gastrointestinal tract in vitro.

    • 2014-05-22
    • BMC microbiology 14(1)
    • • Massimo Marzorati
      • Barbara Vanhoecke
      • Tine De Ryck
      • Mehdi Sadaghian Sadabad
      • Iris Pinheiro
      • Sam Possemiers
      • Pieter Van den Abbeele
      • Lara Derycke
      • Marc Bracke
      • Jan Pieters
      • Tom Hennebel
      • Hermie J Harmsen
      • Willy Verstraete
      • Tom Van de Wiele

    • PubMed: 24884540
    • DOI: 10.1186/1471-2180-14-133

    2 Insights on

    • Reduced IL-8 Production
    • Reduced Inflammation

    • Low evidence
    • Highly Cited

  • Effects of Lactobacillus paracasei CNCM I-4034, Bifidobacterium breve CNCM I-4035 and Lactobacillus rhamnosus CNCM I-4036 on Hepatic Steatosis in Zucker Rats

    • 2014-05-22
    • RCT
    • PLoS ONE 9(5)
    • • J. Plaza-Díaz
      • C. Gómez-Llorente
      • F. Abadía-Molina
      • M. J. Sáez-Lara
      • L. Campaña‐Martín
      • S. Muñoz-Quezada
      • F. Romero
      • Á. Gil
      • L. Fontana

    • PubMed: 24852284
    • DOI: 10.1371/journal.pone.0098401

    9 Insights on

    • Reduced TNF-α Levels
    • Reduced Plasma Lipopolysaccharide Levels
    • Reduced Hepatic Steatosis
    • Reduced IL-6 Levels
    • Reduced Serum LPS Levels
    • Reduced Serum IL-6 Levels
    • Reduced Serum TNF-Alpha Level
    • Reduced Serum TNF-α Levels
    • Reduced Hepatic Neutral Lipids

    • Low evidence
    • Rigorous Journal
    • Animal Study

  • Lactobacillus acidophilus NCFM affects colonic mucosal opioid receptor expression in patients with functional abdominal pain ‐ a randomised clinical study

    • 2014-05-22
    • RCT
    • Alimentary Pharmacology & Therapeutics 40(2)
    • • T. Ringel-Kulka
      • Jason R. Goldsmith
      • Ian M. Carroll
      • Silvana P. Barros
      • O. Palsson
      • Christian Jobin
      • Christian Jobin
      • Y. Ringel

    • PubMed: 24853043
    • DOI: 10.1111/apt.12800

    1 Insight on

    • Improved Symptoms of Functional Bowel Disorders

    • High evidence
    • Rigorous Journal
• May 30

  • Lactobacillus acidophilus and Lactobacillus crispatus culture supernatants downregulate expression of cancer-testis genes in the MDA-MB-231 cell line.

    • 2014-05-30
    • Asian Pacific Journal of Cancer Prevention 15(10)
    • • Rosa Azam
      • S. Ghafouri-Fard
      • M. Tabrizi
      • M. Modarressi
      • R. Ebrahimzadeh-Vesal
      • M. Daneshvar
      • M. Mobasheri
      • E. Motevaseli

    • PubMed: 24935380
    • DOI: 10.7314/APJCP.2014.15.10.4255

    1 Insight on

    • Decreased Cancer-Testis Antigens

    • Low evidence
    • Rigorous Journal
• Undated – 4 supplement studies

  • Dietary supplementation of Bacillus subtilis and fructooligosaccharide enhance the growth, non-specific immunity of juvenile ovate pompano, Trachinotus ovatus and its disease resistance against Vibrio vulnificus.

    • 2014-05
    • Fish & Shellfish Immunology 38(1)
    • • Qin Zhang
      • Hairui Yu
      • T. Tong
      • Wanping Tong
      • Lanfang Dong
      • Mingzhu Xu
      • Zhicheng Wang

    • PubMed: 24614017
    • DOI: 10.1016/j.fsi.2014.02.008

    13 Insights on

    • Increased Serum Lysozyme Activity
    • Improved Growth Performance
    • Enhanced Disease Resistance
    • Enhanced Immune Response
    • Improved Growth Rate
    • Improved Immunity
    • Enhanced Respiratory Burst Activity
    • Reduced Phagocytic Activity
    • Enhanced Complement Pathway Activity
    • Reduced Mortality Post-Infection
    • Improved Phagocytic Activity
    • Increased Complement Pathway Activity
    • Reduced Cumulative Mortality from Vibrio vulnificus

    • Low evidence
    • Highly Cited

  • Effect of Probiotics Containing Lactobacillus paracasei SD1 on Salivary Mutans Streptococci and Lactobacilli in Orthodontic Cleft Patients: A Double-Blinded, Randomized, Placebo-Controlled Study

    • 2014-05
    • RCT · n = 30
    • The Cleft Palate-Craniofacial Journal 51(3)
    • • W. Ritthagol
      • Chontira Saetang
      • R. Teanpaisan

    • PubMed: 23656594
    • DOI: 10.1597/12-243

    6 Insights on

    • Increased Fecal Lactobacilli
    • Increased Lactobacilli Levels
    • Reduced Mutans Streptococcus Counts
    • Increased Oral Colonization of Lactobacillus Paracasei SD1
    • Reduced Streptococcus Mutans Levels
    • Increased Oral Persistence of Lactobacillus paracasei

    • High evidence

  • Altered Transcription of Murine Genes Induced in the Small Bowel by Administration of Probiotic Strain Lactobacillus rhamnosus HN001

    • 2014-05
    • Clinical Trial
    • Applied and Environmental Microbiology 80(9)
    • • G. Tannock
      • Corinda Taylor
      • B. Lawley
      • D. Loach
      • M. Gould
      • Amy C. Dunn
      • A. McLellan
      • M. Black
      • L. McNoe
      • J. Dekker
      • P. Gopal
      • M. Collett

    • PubMed: 24584241
    • DOI: 10.1128/AEM.00336-14

    2 Insights on

    • Improved Resistance to Intestinal Pathogens
    • Enhanced Epithelial Cell Migration

    • Low evidence
    • Animal Study

  • Draft Genome Sequence of Bifidobacterium animalis subsp. lactis Strain CECT 8145, Able To Improve Metabolic Syndrome In Vivo

    • 2014-05
    • Genome Announcements 2(2)
    • • E. Chenoll
      • F. Codoñer
      • A. Silva
      • J. F. Martínez-Blanch
      • P. Martorell
      • Daniel Ramón
      • S. Genovés

    • PubMed: 24675853
    • DOI: 10.1128/genomeA.00183-14

    2 Insights on

    • Reduced Body Fat
    • Improved Metabolic Syndrome Biomarkers

    • Low evidence