N. Iwabuchi

Food Ingredients & Technology Institute, Morinaga Milk Industry Co., Ltd., 5-1-83 Higashihara, Zama-shi, Kanagawa 252-8583, Japan

Research Areas

• Probiotics and Fermented Foods
• Gut microbiota and health
• Immune Response and Inflammation
• Microbial bioremediation and biosurfactants
• Microbial Metabolic Engineering and Bioproduction

Health Outcomes Studied

• Improved Bowel Movement Frequency
• Improved Gut Microbiota
• Increased Bifidobacteria Levels
• Increased Fecal Acetate Levels
• Increased Fecal Bifidobacteria Levels
• Increased Fecal Immunoglobulin A Levels
• Increased Fecal Secretory IgA Levels
• Increased HDL Cholesterol Levels
• Increased Intestinal Bifidobacteria Levels
• Increased Serum Immunoglobulin A (IgA) Levels
• Reduced Faecal pH
• Reduced Stool Volume
• Reduced Visceral Fat

Papers (21)

• 2026
  Bifidobacterium longum BB536 is associated with improvements in gastrointestinal symptoms and odor-related metabolites in microbiota-defined subgroups of male athletes consuming a high-protein diet: exploratory randomized double‑blind placebo‑controlled trial.10.1080/15502783.2026.2664664
• 2025
  Probiotic viability in the gastrointestinal tract in a randomised placebo controlled trial: combining molecular biology and novel cultivation techniques.10.1163/18762891-bja00055
• 2023
  Heat-killed Lactobacillus helveticus improves mood states: a randomised, double-blind, placebo-controlled study.10.3920/bm2022.0048
• 2023
  Early Probiotic Supplementation of Healthy Term Infants with Bifidobacterium longum subsp. infantis M-63 Is Safe and Leads to the Development of Bifidobacterium-Predominant Gut Microbiota: A Double-Blind, Placebo-Controlled Trial10.3390/nu15061402
• 2023
  Heat-killed Lactobacillus helveticus improves mood states: a randomised, double-blind, placebo-controlled study.10.3920/BM2022.0048
• 2021
  Immuno-modulation by heat-killed Lacticaseibacillus paracasei MCC1849 and its application to food products10.1177/20587384211008291
• 2021
  Colonization of Supplemented Bifidobacterium breve M-16V in Low Birth Weight Infants and Its Effects on Their Gut Microbiota Weeks Post-administration10.3389/fmicb.2021.610080
• 2020
  Maternal supplementation with Bifidobacterium breve M-16V prevents their offspring from allergic airway inflammation accelerated by the prenatal exposure to an air pollutant aerosol10.1371/journal.pone.0238923
• 2019
  Exploring the Science behind Bifidobacterium breve M-16V in Infant Health10.3390/nu11081724
• 2018
  Orally administered heat-killed Lactobacillus paracasei MCC1849 enhances antigen-specific IgA secretion and induces follicular helper T cells in mice10.1371/journal.pone.0199018
• 2018
  Effects of paraprobiotic Lactobacillus paracasei MCC1849 supplementation on symptoms of the common cold and mood states in healthy adults.10.3920/BM2017.0197
• 2018
  Effects of Bifidobacterium breve B-3 on body fat reductions in pre-obese adults: a randomized, double-blind, placebo-controlled trial10.12938/bmfh.18-001
• 2016
  Bifidobacterium breve prevents necrotising enterocolitis by suppressing inflammatory responses in a preterm rat model.10.3920/BM2015.0035
• 2016
  Effect of repeated oral administration of Bifidobacterium longum BB536 on apomorphine-induced rearing behavior in mice10.12938/bmfh.2016-004
• 2015
  The effects of non-viable Lactobacillus on immune function in the elderly: a randomised, double-blind, placebo-controlled study10.3109/09637486.2015.1126564
• 2015
  Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota.10.2332/allergolint.13-OA-0683
• 2012
  Clinical effects of probiotic Bifidobacterium longum BB536 on immune function and intestinal microbiota in elderly patients receiving enteral tube feeding.10.1177/0148607112467819
• 2011Primary author
  Oral administration of Bifidobacterium longum ameliorates influenza virus infection in mice.10.1248/BPB.34.1352
• 2009
  Suppressive effects of bifidobacterium breve strain M-16V on T-helper type 2 immune responses in a murine model.10.1248/BPB.32.760
• 2009Primary author
  Suppressive effects of Bifidobacterium longum on the production of Th2-attracting chemokines induced with T cell-antigen-presenting cell interactions.10.1111/j.1574-695X.2008.00510.x
• 2007
  Influence of Bifidobacterium longum BB536 intake on faecal microbiota in individuals with Japanese cedar pollinosis during the pollen season.10.1099/JMM.0.47306-0