Alzheimer's disease
Alzheimer's disease (AD) is a neurodegenerative disorder that primarily impairs cognitive functions, particularly memory, and is the leading cause of dementia, accounting for 60-70% of cases. It begins slowly and progressively worsens, leading to severe cognitive decline, loss of bodily functions, and ultimately death, with an average life expectancy of three to twelve years after diagnosis.
Health Outcomes
- Activated Mitophagy Pathway
- Activation of G-Protein Coupled Receptors
- Altered Neurobiological Markers
- Changed Functional Connectivity
- Changed Leukocyte Telomere Length
- Confirmed Safety of Treatment
- Decreased Composite Scores
- Delayed Disease Progression
- Delayed Neurodegeneration
- Elevated Redox Status
- Elevated Serum Acetylcholine Levels
- Enhanced Antioxidant Activity
- Enhanced Antioxidant Enzyme Activity
- Enhanced Antioxidant Levels
- Enhanced Auto-aggregation Ability
- Enhanced Autophagy
- Enhanced BDNF-TrkB Signaling
- Enhanced Brain-Derived Neurotrophic Factor Levels
- Enhanced Caspase-3 Activity
- Enhanced Endoplasmic Reticulum Stress Response
- Enhanced Mitochondrial Biogenesis
- Enhanced Neurogenesis in Adults
- Enhanced Neurological Disorder Management
- Enhanced Neuropharmacological Function
- Enhanced Polyphenol Levels
- Enhanced Radical Scavenging Ability
- Enhanced Reactive Oxygen Species Resistance
- Enhanced Superoxide Dismutase Activity
- Facilitated Mitophagy
- Genome Sequencing / Genome Characterization
- Impaired Vacuolar Function
- Improved Activities of Daily Living
- Improved Agility and Coordination Performance
- Improved Aging-Related Changes
- Improved Alzheimer Disease
- Improved Alzheimer Disease Assessment Scale-Cognitive Subscale Score
- Improved Alzheimer Disease Assessment Scale-Noncognitive Subscale Score
- Improved Analytical Accuracy
- Improved Anti-Aging Effects
- Improved Antioxidant Activity
- Improved Antioxidant Capacity
- Improved Antioxidative Capacity
- Improved Antioxidative Response
- Improved Barthel Index
- Improved Barthel Index Score
- Improved Blood-Brain Barrier Function
- Improved Blood-Brain Barrier Integrity
- Improved Brain Activity
- Improved Brain Function
- Improved Brain Health
- Improved Brain-Derived Neurotrophic Factor Level
- Improved Cell-Cell Signalling
- Improved Central Nervous System Function
- Improved Cerebral Blood Flow Velocity
- Improved Cognition
- Improved Cognitive Behavior
- Improved Cognitive Function
- Improved Cognitive Functioning
- Improved Cognitive Orientation Function
- Improved Cognitive Performance
- Improved Cognitive Prognosis
- Improved Cognitive Score
- Improved Cognitive Screen Score
- Improved Cognitive Speed
- Improved Communication
- Improved Cytoprotection During Oxidative Stress
- Improved Decision Accuracy
- Improved Decision-Making Accuracy
- Improved Delayed Memory
- Improved Delayed Word Recall
- Improved Global Assessment
- Improved Global Clinical Impression
- Improved Global Cognition
- Improved Glutathione Level
- Improved Glutathione Redox Ratio
- Improved Gut Microbiota with Reversal of Alzheimer’s Disease-related Changes
- Improved Health in Elderly Populations
- Improved Healthy Aging
- Improved Hippocampal Fractional Anisotropy
- Improved MMSE Score
- Improved Mathematical Processing
- Improved Memory Function
- Improved Memory Performance
- Improved Mini-Mental State Examination Score
- Improved Mitochondrial Function
- Improved Neurodegenerative Disease Symptoms
- Improved Neurodegenerative Disorder
- Improved Neurological Health
- Improved Neurological Symptoms
- Improved Neuronal Survival
- Improved Neuroplasticity Biomarkers
- Improved Neuroprotection
- Improved Neuropsychiatric Outcomes
- Improved Neurotransmitter Metabolism
- Improved Neurotransmitter Profile
- Improved Neurotrophic Signaling
- Improved Orientation in Time (MMSE Subscale)
- Improved Oxidative Stress Biomarker
- Improved Oxidative Stress Marker
- Improved Oxidative Stress Resistance
- Improved Oxidative Stress Tolerance
- Improved Parent/Caregiver Quality of Life
- Improved Pattern Separation
- Improved Performance Mastery
- Improved Processing Speed
- Improved Reaction Time
- Improved Recognition Memory
- Improved Redox Homeostasis
- Improved Responder Rate
- Improved Saliva Flow Rate
- Improved Serum Biochemical Catalase Levels
- Improved Set-Shifting Reaction Time
- Improved Short-term Memory
- Improved Simon Task Accuracy
- Improved Simulated Game Total Completion Time
- Improved Spatial Learning Ability
- Improved Superoxide Dismutase Activity
- Improved Superoxide Dismutase Level
- Improved Synaptic Plasticity
- Improved Telephone Interview for Cognitive Status Score
- Improved Total Antioxidative Status
- Improved Visual-Spatial Function
- Improved Visuo-Cognitive Processing
- Improved Visuospatial Constructional Skills
- Improved Working Memory
- Increased AMPK Activation
- Increased Abundance of Specific Anti-Alzheimer's Disease Bacteria
- Increased Acetylcholine Levels
- Increased Antioxidant Enzyme Levels
- Increased Apolipoprotein E Levels
- Increased Apoptosis
- Increased Autophagy
- Increased Bioavailability of Phenolics
- Increased Brain Choline Level
- Increased Carnosine Level
- Increased Catalase Expression
- Increased Cellular Apoptosis
- Increased Constipation Risk
- Increased Cysteine Level
- Increased DHA Level
- Increased DNA Damage
- Increased Delta Power in EEG
- Increased ER Stress-Associated Proteins
- Increased Expression of Heat Shock Protein 25
- Increased GSH/GSSG Ratio
- Increased Glutathione Level
- Increased Glutathione Levels
- Increased Glutathione Peroxidase Activity
- Increased Glutathione Peroxidase Levels
- Increased Glycine Level
- Increased Homocysteine Level
- Increased Hydrogen Peroxide Production
- Increased Interleukin-1 Beta Production
- Increased Malondialdehyde Levels
- Increased Mortality
- Increased Mortality Rate
- Increased Myo-Inositol Level
- Increased Neurogenesis
- Increased Neuronal Cell Survival
- Increased Nrf2 Level
- Increased Oxidative Stress
- Increased Oxidative Stress Tolerance
- Increased Plasma Kynurenic Acid Levels
- Increased Plasma Omega-3 Fatty Acids
- Increased Plasma Serum Alpha-Amyloid Protein
- Increased Polyphenol Level
- Increased Postsynaptic Density Protein 95 Levels
- Increased Prefrontal Cortex Deoxygenated Hemoglobin Level
- Increased Pro-inflammatory Cytokine Production
- Increased Reactive Oxygen Species Production
- Increased Reactive Oxygen Species Response
- Increased Serine Level
- Increased Serum NAD+ Levels
- Increased Superoxide Dismutase Activity
- Increased Superoxide Dismutase Level
- Increased Thiol Level
- Increased Total Serum Antioxidant Capacity
- Increased Total Thiol Level
- Increased Tumor Necrosis Factor-Alpha Levels
- Increased Uncoupling Protein 2 Expression
- Inhibited Activation of Apoptotic Biomarkers
- Maintained Acetylcholine Levels
- Maintained Cognitive Function
- Maintained or Improved Cognitive Function
- Modified Resting-State Brain Connectivity
- Modulated Metabolite Profile
- Modulated Signal Transduction Pathways
- Nervous System Dysfunction in Host
- Neuroprotection in Neurodegenerative Diseases
- No Change in Cytokines or Chemokines Levels
- No Change in Plasma GABA Levels
- No Change in Subjective Appetite
- No Significant Cognitive Improvement
- No Significant Impact on Bacterial Community Composition or Diversity
- No Significant Improvement in Memory Retention
- No Significant Weight Change
- Normalized Serum IL-1β Levels
- Preserved Hippocampal Neurogenesis
- Prevented Neurometabolic Decline
- Prevention of Neurological Disorders
- Protection Against Oxidative Stress
- Reduced Accommodation Variability
- Reduced Adherence Attrition
- Reduced Advanced Glycation End Product Level
- Reduced Age-Related Inflammation
- Reduced Aging-related Changes
- Reduced Alzheimer's Disease-Associated Gut Dysbiosis
- Reduced Alzheimer's Disease-Related Neurotoxicity
- Reduced Alzheimer’s Disease Pathology
- Reduced Amyloid Precursor Protein Level
- Reduced Amyloid-β Levels
- Reduced Apoptosis
- Reduced BACE1 mRNA Level
- Reduced Brain Atrophy
- Reduced Brain Inflammation
- Reduced Brain Oxidative Stress
- Reduced Catalase Activity
- Reduced Cellular Damage
- Reduced Cellular Senescence
- Reduced Central Nervous System Symptom Severity
- Reduced Choking Index
- Reduced Cognitive Decline
- Reduced Cognitive Function
- Reduced Cognitive Impairment
- Reduced Confusion and Bewilderment
- Reduced Cortical Excitation
- Reduced Cytoskeleton Disruption
- Reduced Dietary Advanced Glycation End Product Intake
- Reduced Disability
- Reduced Dysphagia Symptom Score
- Reduced Expression of ADAM17
- Reduced Ferroptosis
- Reduced Folate Deficiency
- Reduced Free Radical Levels
- Reduced Glial Cell Activation
- Reduced Glutamate Level
- Reduced Glutathione Loss
- Reduced Glutathione Redox Ratio
- Reduced Glycative Stress Marker Level
- Reduced Hippocampal Apoptosis
- Reduced Homocysteine Level
- Reduced Hydrogen Sulfide Level
- Reduced IL-1β Levels
- Reduced IkappaB Alpha Degradation
- Reduced Indoleamine 2,3-Dioxygenase Activity
- Reduced Inflammatory Biomarker Level
- Reduced Insulin/IGF-1 Signaling
- Reduced Interleukin-1β Levels
- Reduced Kynurenine-Tryptophan Ratio
- Reduced Levels of Anti-Inflammatory Cytokines
- Reduced Lipofuscin Accumulation
- Reduced Lymphocytic Genome Damage
- Reduced Lysophosphatidylcholine 18:1 Level
- Reduced Lysophosphatidylcholine Level
- Reduced Lysophosphatidylethanolamine Level
- Reduced Malonaldehyde Levels
- Reduced N-acetylaspartate Level
- Reduced NADPH Oxidase Activity
- Reduced NF-kappaB Nuclear Translocation
- Reduced Neurodegeneration Symptoms
- Reduced Neurodegenerative Disease-Related Dysfunction
- Reduced Neuroinflammation
- Reduced Neuroinflammatory Markers
- Reduced Neurological Symptoms
- Reduced Neuronal Death
- Reduced Neurotoxicity
- Reduced Nuclear Factor Kappa-B Level
- Reduced Oxidative Stress
- Reduced Oxidative Stress Index
- Reduced Oxidative Stress Marker
- Reduced Oxidative Stress Marker Level
- Reduced Oxidative Stress Markers
- Reduced Oxidized Glutathione Level
- Reduced Plasma LPS Levels
- Reduced Polyamine Levels
- Reduced Prefrontal Cortex Oxygen Saturation
- Reduced Prefrontal Cortex Oxygenated Hemoglobin
- Reduced Prefrontal Cortex Total Hemoglobin Level
- Reduced Pro-Inflammatory Factor TNF-α
- Reduced Pro-Inflammatory Fatty Acids
- Reduced Pro-inflammatory Cytokine Levels
- Reduced Proinflammatory Cytokines in Middle-aged Adults
- Reduced Proinflammatory Signaling
- Reduced Proportion of Volunteers with At Least One CID
- Reduced Protein Carbonyl Level
- Reduced Protein Carbonyl Levels
- Reduced Protein Oxidation
- Reduced Proteotoxicity
- Reduced Psychological Score
- Reduced Reaction Time
- Reduced Reactive Oxygen Species Formation
- Reduced Response Time
- Reduced Response Time on Flanker Task
- Reduced Retroactive Interference
- Reduced Senescence-Associated Secretory Phenotype
- Reduced Serum BDNF Levels
- Reduced Serum Glutamate Levels
- Reduced Serum MDA Concentrations
- Reduced Serum Malondialdehyde Levels
- Reduced Set-Shifting Reversal Error
- Reduced Simple Reaction Time
- Reduced Soluble Receptor of Advanced Glycation End Product Level
- Reduced Subjective Cognitive Decline
- Reduced Th17 Cell
- Reduced cFos Expression in Brain Areas
- Regulated Microglial Activation
- Regulated Oxidative Stress
- Regulation of Neuroactive Ligand Receptor Interaction Pathway
- Reproduced Protective Effect via Extracellular Vesicles
- Restored Neurodegeneration-Associated Metabolic Alterations
- Restored SOD Activity Levels
- Similar Frequency of Adverse Events
- Stabilized Cell Membranes
- Stabilized Disease Progression
- Stabilized Neurofilament Light Chain Level
- Stable Brain Metabolite Levels
- Supported Physiological Function in Elderly
- Unchanged Monocyte Chemoattractant Protein-1 Levels
- Worsened Alzheimer's Disease Assessment Scale