March 2009 Supplement Research Papers

• March 1

  • Administration of Pediococcus acidilactici or Saccharomyces cerevisiae boulardii modulates development of porcine mucosal immunity and reduces intestinal bacterial translocation after Escherichia coli challenge.

    • 2009-03-01
    • RCT
    • Journal of Animal Science 87(3)
    • • M. Lessard
      • M. Dupuis
      • N. Gagnon
      • E. Nadeau
      • J. Matte
      • J. Goulet
      • J. Fairbrother

    • PubMed: 19028865
    • DOI: 10.2527/jas.2008-0919

    6 Insights on

    • Reduced Bacterial Translocation
    • Modulated Lymphocyte Populations
    • Improved CD4- CD8+ low T Cell Percentage in Ileum
    • Altered IgA Concentration in Ileal Flushes
    • Reduced Bacterial Translocation to Mesenteric Lymph Nodes
    • Increased CD4(-)CD8(+low) T Cell Count in Ileum

    • High evidence
    • Highly Cited
• March 13

  • Safety Assessment of Lactobacillus fermentum CECT5716, a probiotic strain isolated from human milk

    • 2009-03-13
    • RCT · n = 40
    • Journal of Dairy Research 76(2)
    • • F. Lara‐Villoslada
      • S. Sierra
      • M. Díaz-Ropero
      • J. M. Rodríguez
      • J. Xaus
      • M. Olivares

    • PubMed: 19281631
    • DOI: 10.1017/S0022029909004014

    9 Insights on

    • Nonpathogenic Even at High Doses
    • Reduced Bacterial Translocation
    • Absence of Bacteremia
    • Nonpathogenic Condition
    • No Adverse Health Effects
    • No Significant Weight Change
    • Absence of Bacterial Translocation to Liver or Spleen
    • No Change in Oxidative Stress Markers
    • Unchanged Body Weight

    • Low evidence
    • Animal Study
• Undated – 4 supplement studies

  • Early treatment with Lactobacillus delbrueckii strain induces an increase in intestinal T-cells and granulocytes and modulates immune-related genes of larval Dicentrarchus labrax (L.).

    • 2009-03
    • Clinical Trial
    • Fish & Shellfish Immunology 26(3)
    • • S. Picchietti
      • A. Fausto
      • E. Randelli
      • O. Carnevali
      • A. Taddei
      • F. Buonocore
      • G. Scapigliati
      • L. Abelli

    • PubMed: 18996487
    • DOI: 10.1016/j.fsi.2008.10.008

    5 Insights on

    • Improved Immune Function
    • Reduced Inflammation Levels
    • Enhanced Immune Function
    • Increased Intestinal T-Cell Count
    • Reduced Pro-inflammatory Gene Transcription

    • Low evidence
    • Highly Cited
    • Animal Study

  • Bacillus coagulans significantly improved abdominal pain and bloating in patients with IBS.

    • 2009-03
    • RCT · n = 44
    • Postgraduate Medicine 121(2)
    • • Larysa Hun

    • PubMed: 19332970
    • DOI: 10.3810/pgm.2009.03.1984

    4 Insights on

    • Reduced Bloating
    • Reduced Flatulence
    • Reduced Abdominal Pain
    • Improved Treatment Safety

    • High evidence
    • Highly Cited

  • A patented strain of Bacillus coagulans increased immune response to viral challenge.

    • 2009-03
    • Clinical Trial · n = 10
    • Postgraduate Medicine 121(2)
    • • Mira Baron

    • PubMed: 19332969
    • DOI: 10.3810/pgm.2009.03.1971

    2 Insights on

    • Improved Immune Response to Adenovirus
    • Improved Immune Response to Influenza A

    • Moderate evidence

  • Influence of vitamins and osmolites on growth and bacteriocin production by Lactobacillus salivarius CRL 1328 in a chemically defined medium.

    • 2009-03
    • Canadian Journal of Microbiology 55(3)
    • • E. Vera Pingitore
      • E. Hebert
      • F. Sesma
      • M. Nader-Macías

    • PubMed: 19370073
    • DOI: 10.1139/w08-092

    1 Insight on

    • Improved Growth

    • Low evidence