A. Ouwehand

DuPont (Finland)

Research Areas

• Probiotics and Fermented Foods
• Gut microbiota and health
• Microbial Metabolites in Food Biotechnology
• Digestive system and related health
• Infant Nutrition and Health

Health Outcomes Studied

• Improved Bowel Movement Frequency
• Increased Immunoglobulin G Levels
• Increased Serum Immunoglobulin A (IgA) Levels
• Increased Total Bacterial Count
• Reduced Abdominal Pain
• Reduced Diarrhea Rate
• Reduced Flatulence
• Reduced Interleukin-4 Levels
• Reduced Interleukin-6 Levels
• Reduced Straining

Papers (26)

• 2023
  Lactobacillus acidophilus NCFM and Lactiplantibacillus plantarum Lp-115 inhibit Helicobacter pylori colonization and gastric inflammation in a murine model10.3389/fcimb.2023.1196084
• 2022
  One Giant Leap from Mouse to Man: The Microbiota-Gut-Brain Axis in Mood Disorders and Translational Challenges Moving towards Human Clinical Trials.10.3390/nu14030568
• 2022
  Bifidobacterium animalis subsp. lactis Bi-07 supports lactose digestion in vitro and in randomized, placebo- and lactase-controlled clinical trials10.1093/ajcn/nqac264
• 2021
  Bifidobacterium animalis subsp. lactis HN019 Effects on Gut Health: A Review10.3389/fnut.2021.790561
• 2021
  Evaluation of 2’-Fucosyllactose and Bifidobacterium longum Subspecies infantis on Growth, Organ Weights, and Intestinal Development of Piglets10.3390/nu14010199
• 2021
  Effects of Bifidobacterium animalis ssp. lactis 420 on gastrointestinal inflammation induced by a nonsteroidal anti‐inflammatory drug: A randomized, placebo‐controlled, double‐blind clinical trial10.1111/bcp.14880
• 2020
  Technological Characterisation of Probiotic Lactic Acid Bacteria as Starter Cultures for Dry Fermented Sausages10.3390/foods9050596
• 2020
  Bifidobacterium animalis subsp. lactis 420 for Metabolic Health: Review of the Research10.3390/nu12040892
• 2020
  Bifidobacterium animalis subsp lactis HN019 presents antimicrobial potential against periodontopathogens and modulates the immunological response of oral mucosa in periodontitis patients10.1371/journal.pone.0238425
• 2018
  Effects of 28-day Bifidobacterium animalis subsp. lactis HN019 supplementation on colonic transit time and gastrointestinal symptoms in adults with functional constipation: A double-blind, randomized, placebo-controlled, and dose-ranging trial10.1080/19490976.2017.1412908
• 2017
  Irritable bowel syndrome symptom severity improves equally with probiotic and placebo10.3748/wjg.v22.i48.10631
• 2017
  Effect of probiotic supplementation on total lactobacilli, bifidobacteria and short chain fatty acids in 2–5-year-old children10.1080/16512235.2017.1298340
• 2017
  Safety evaluation of HOWARU® Restore (Lactobacillus acidophilus NCFM, Lactobacillus paracasei Lpc-37, Bifidobacterium animalis subsp. lactis Bl-04 and B. lactis Bi-07) for antibiotic resistance, genomic risk factors, and acute toxicity.10.1016/j.fct.2017.10.037
• 2015
  Modulation of the host response by probiotic Lactobacillus brevis CD2 in experimental gingivitis.10.1111/odi.12332
• 2014
  Effect of yogurt containing polydextrose, Lactobacillus acidophilus NCFM and Bifidobacterium lactis HN019: a randomized, double-blind, controlled study in chronic constipation.10.1186/1475-2891-13-75
• 2014
  Xylo-oligosaccharides alone or in synbiotic combination with Bifidobacterium animalis subsp. lactis induce bifidogenesis and modulate markers of immune function in healthy adults: a double-blind, placebo-controlled, randomised, factorial cross-over study10.1017/S0007114513004261
• 2014
  Consumption of Bifidobacterium lactis Bi-07 by healthy elderly adults enhances phagocytic activity of monocytes and granulocytes10.1017/jns.2013.31
• 2013Primary author
  Lactobacillus acidophilus supplementation in human subjects and their resistance to enterotoxigenic Escherichia coli infection10.1017/S0007114513002547
• 2012
  Probiotic cheese containing Lactobacillus rhamnosus HN001 and Lactobacillus acidophilus NCFM® modifies subpopulations of fecal lactobacilli and Clostridium difficile in the elderly.10.1007/s11357-011-9208-6
• 2011
  Dose-response effect of Bifidobacterium lactis HN019 on whole gut transit time and functional gastrointestinal symptoms in adults10.3109/00365521.2011.584895
• 2010
  Synbiotic effects of lactitol and Lactobacillus acidophilus NCFM™ in a semi-continuous colon fermentation model.10.3920/BM2009.0033
• 2008
  Effects of seven potential probiotic strains on specific immune responses in healthy adults: a double-blind, randomized, controlled trial.10.1111/j.1574-695x.2008.00413.x
• 2008Primary author
  Influence of a combination of Lactobacillus acidophilus NCFM and lactitol on healthy elderly: intestinal and immune parameters.10.1017/S0007114508003097
• 2007
  A probiotic, Lactobacillus fermentum ME-3, has antioxidative capacity in soft cheese spreads with different fats.10.3168/JDS.2006-810
• 2003
  Immune enhancement in rainbow trout (Oncorhynchus mykiss) by potential probiotic bacteria (Lactobacillus rhamnosus).10.1016/S1050-4648(03)00023-8
• 2000Primary author
  The mucus binding of Bifidobacterium lactis Bb12 is enhanced in the presence of Lactobacillus GG and Lact. delbrueckii subsp. bulgaricus10.1046/j.1472-765x.2000.00590.x