T. Tompkins

Lallemand (Canada)

Research Areas

• Gut microbiota and health
• Probiotics and Fermented Foods
• Gastrointestinal motility and disorders
• Clostridium difficile and Clostridium perfringens research
• Diet and metabolism studies

Health Outcomes Studied

• Improved Bowel Movement Frequency
• Improved Insulin Levels
• Improved Insulin Sensitivity
• Increased Fecal Bile Acid Levels
• Reduced Body Weight
• Reduced Flatulence
• Reduced Low-Density Lipoprotein Level
• Reduced Total Cholesterol Levels

Papers (23)

• 2026
  Efficacy and safety of a particulate yeast β-glucan preparation in the treatment of seasonal allergic rhinitis (BETALL): a randomised placebo-controlled crossover trial protocol.10.1186/s13063-026-09702-7
• 2025
  Trans-resveratrol reduces visible signs of skin ageing in healthy adult females over 40: an 8-week randomized placebo-controlled trial.10.3389/fragi.2025.1727244
• 2022
  Lacticaseibacillus rhamnosus HA-114 improves eating behaviors and mood-related factors in adults with overweight during weight loss: a randomized controlled trial10.1080/1028415X.2022.2081288
• 2022
  Lacticaseibacillus rhamnosus R0011 secretome attenuates Salmonella enterica serovar Typhimurium secretome-induced intestinal epithelial cell monolayer damage and pro-inflammatory mediator production in intestinal epithelial cell and antigen-presenting cell co-cultures10.3389/fmicb.2022.980989
• 2021
  Efficacy of a Multi-Strain Probiotic Formulation in Pediatric Populations: A Comprehensive Review of Clinical Studies10.3390/nu13061908
• 2020
  Safety and Effect of a Low- and High-Dose Multi-Strain Probiotic Supplement on Microbiota in a General Adult Population: A Randomized, Double-Blind, Placebo-Controlled Study10.1080/19390211.2020.1749751
• 2020
  Supplementation with Combined Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 Across Development Reveals Sex Differences in Physiological and Behavioural Effects of Western Diet in Long–Evans Rats10.3390/microorganisms8101527
• 2020
  Efficacy of Lactobacillus paracasei HA-196 and Bifidobacterium longum R0175 in Alleviating Symptoms of Irritable Bowel Syndrome (IBS): A Randomized, Placebo-Controlled Study10.3390/nu12041159
• 2019
  Three probiotic strains exert different effects on plasma bile acid profiles in healthy obese adults: randomised, double-blind placebo-controlled crossover study.10.3920/bm2018.0151
• 2018
  Bifidobacterium longum and Lactobacillus helveticus Synergistically Suppress Stress-related Visceral Hypersensitivity Through Hypothalamic-Pituitary-Adrenal Axis Modulation10.5056/jnm16167
• 2016
  Calcium phosphate supplementation increases faecal Lactobacillus spp. in a randomised trial of young adults.10.3920/BM2014.0168
• 2016
  Effectiveness of Lactobacillus helveticus and Lactobacillus rhamnosus for the management of antibiotic-associated diarrhoea in healthy adults: a randomised, double-blind, placebo-controlled trial10.1017/S0007114516001665
• 2013
  Probiotic gut effect prevents the chronic psychological stress‐induced brain activity abnormality in mice10.1111/nmo.12295
• 2012
  Draft Genome Sequence of Probiotic Strain Pediococcus acidilactici MA18/5M10.1128/JB.06563-11
• 2012Primary author
  Draft Genome Sequence of Probiotic Strain Lactobacillus rhamnosus R001110.1128/JB.06584-11
• 2012Primary author
  Complete Genome Sequence of Lactobacillus helveticus R0052, a Commercial Probiotic Strain10.1128/JB.01638-12
• 2011
  Genetic diversity in proteolytic enzymes and amino acid metabolism among Lactobacillus helveticus strains.10.3168/jds.2010-4068
• 2011
  Combination of Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 reduces post-myocardial infarction depression symptoms and restores intestinal permeability in a rat model.10.1017/S0007114511005137
• 2011
  A comprehensive post-market review of studies on a probiotic product containing Lactobacillus helveticus R0052 and Lactobacillus rhamnosus R0011.10.3920/BM2011.0032
• 2010Primary author
  A comprehensive review of post-market clinical studies performed in adults with an Asian probiotic formulation.10.3920/bm2008.1005
• 2010
  Sequence analysis of plasmid pIR52-1 from Lactobacillus helveticus R0052 and investigation of its origin of replication.10.1016/j.plasmid.2009.12.004
• 2010
  Effect of fermentation by pure and mixed cultures of Streptococcus thermophilus and Lactobacillus helveticus on isoflavone and B-vitamin content of a fermented soy beverage.10.1016/j.fm.2010.06.003
• 2006
  Lactobacillus suntoryeus Cachat and Priest 2005 is a later synonym of Lactobacillus helveticus (Orla-Jensen 1919) Bergey et al. 1925 (Approved Lists 1980).10.1099/IJS.0.64001-0