March 2010 Supplement Research Papers

• March 1

  • Survival and metabolic activity of the GanedenBC30 strain of Bacillus coagulans in a dynamic in vitro model of the stomach and small intestine.

    • 2010-03-01
    • Beneficial Microbes 1(1)
    • • A. Maathuis
      • D. Keller
      • S. Farmer

    • PubMed: 21831748
    • DOI: 10.3920/BM2009.0009

    3 Insights on

    • Increased Lactate Levels
    • Improved Protein Digestion
    • Reduced Intestinal Symptoms from Carbohydrate Sensitivity

    • Low evidence
    • Highly Cited

  • Clinical efficacy comparison of Saccharomyces boulardii and yogurt fluid in acute non-bloody diarrhea in children: a randomized, controlled, open label study.

    • 2010-03-01
    • RCT · n = 55
    • The American Journal of Tropical Medicine and Hygiene 82(3)
    • • M. Eren
      • E. Dinleyici
      • Y. Vandenplas

    • PubMed: 20207879
    • DOI: 10.4269/ajtmh.2010.09-0529

    2 Insights on

    • Reduced Duration of Diarrhea
    • Resolution of Diarrhea

    • High evidence
    • Rigorous Journal
• March 2

  • Oral administration of Lactobacillus acidophilus induces IL-12 production in spleen cell culture of BALB/c mice bearing transplanted breast tumour.

    • 2010-03-02
    • British Journal of Nutrition 104(2)
    • • M. Yazdi
      • M. M. Soltan Dallal
      • Z. Hassan
      • M. Holakuyee
      • S. Agha Amiri
      • M. Abolhassani
      • M. Mahdavi

    • PubMed: 20193099
    • DOI: 10.1017/S0007114510000516

    8 Insights on

    • Reduced Tumor Growth
    • Increased Interleukin-12 Production
    • Reduced Transforming Growth Factor Beta Levels
    • Enhanced Delayed-Type Hypersensitivity Response
    • Reduced Tumor Growth Rate
    • Increased IL-12 Production in Splenocytes
    • Increased IL-12 Production
    • Improved Delayed-Type Hypersensitivity Response

    • Moderate evidence
• March 10

  • Regulation of abdominal adiposity by probiotics (Lactobacillus gasseri SBT2055) in adults with obese tendencies in a randomized controlled trial

    • 2010-03-10
    • RCT · n = 87
    • European Journal of Clinical Nutrition 64(6)
    • • Y. Kadooka
      • M. Sato
      • K. Imaizumi
      • A. Ogawa
      • Ken Ikuyama
      • Y. Akai
      • M. Okano
      • M. Kagoshima
      • T. Tsuchida

    • PubMed: 20216555
    • DOI: 10.1038/ejcn.2010.19

    11 Insights on

    • Reduced Waist Circumference
    • Reduced Body Mass Index
    • Reduced Body Weight
    • Reduced Abdominal Fat
    • Increased Adiponectin Levels
    • Reduced Hip Circumference
    • Reduced Visceral Fat Mass
    • Reduced Abdominal Visceral Fat
    • Reduced Abdominal Subcutaneous Fat
    • Reduced BMI
    • Increased Serum High-Molecular Weight Adiponectin

    • High evidence
    • Highly Cited
• March 24

  • GanedenBC30™ cell wall and metabolites: anti-inflammatory and immune modulating effects in vitro

    • 2010-03-24
    • BMC Immunology 11(1)
    • • G. Jensen
      • K. Benson
      • Steve G. Carter
      • J. Endres

    • PubMed: 20331905
    • DOI: 10.1186/1471-2172-11-15

    9 Insights on

    • Increased PMN Cell Phagocytic Capacity
    • Reduced Hepatic Oxidative Stress
    • Increased Anti-Inflammatory Cytokine IL-10
    • Modulated Cytokine Production
    • Improved Immune Surveillance
    • Reduced PMN Cell Migration Towards Inflammatory Mediators
    • Increased Expression of Activation Markers on NK Cells
    • Improved PHA-Induced Cytokine Production
    • Increased Cytokine Production

    • Low evidence
    • Highly Cited
• March 31

  • Estimation of combined effects of carbon and nitrogen sources on the growth and bacteriocin production of Lactobacillus salivarius from human source

    • 2010-03-31
    • Journal of Basic Microbiology 50(2)
    • • M. S. J. Tomás
      • E. Bru
      • M. E. Nader-Macías

    • PubMed: 20082367
    • DOI: 10.1002/jobm.200900122

    1 Insight on

    • Reduced Urogenital Infections

    • Low evidence
• Undated – 4 supplement studies

  • Distinct Bifidobacterium strains drive different immune responses in vitro.

    • 2010-03
    • International Journal of Food Microbiology 138(1-2)
    • • P. López
      • M. Gueimonde
      • A. Margolles
      • A. Suárez

    • PubMed: 20071048
    • DOI: 10.1016/j.ijfoodmicro.2009.12.023

    1 Insight on

    • Increased Th17 Polarization

    • Low evidence
    • Highly Cited

  • Hypocholesterolemic effects of Lactobacillus plantarum KCTC3928 by increased bile acid excretion in C57BL/6 mice.

    • 2010-03
    • RCT · n = 3
    • Nutrition 26(3)
    • • J. Jeun
      • Suk-Whan Kim
      • Sung‐yun Cho
      • H. Jun
      • Hyun-Jin Park
      • Jae-gu Seo
      • M. Chung
      • Sung-Joon Lee

    • PubMed: 19695834
    • DOI: 10.1016/j.nut.2009.04.011

    3 Insights on

    • Reduced Serum Triacylglycerols
    • Reduced LDL Cholesterol
    • Increased Fecal Bile Acid Levels

    • Low evidence
    • Highly Cited
    • Animal Study

  • Effect of dietary probiotic, Bacillus coagulans, on growth performance, chemical composition, and meat quality of Guangxi Yellow chicken.

    • 2010-03
    • RCT
    • Poultry Science 89(3)
    • • Xuxia Zhou
      • Yan-bo Wang
      • Q. Gu
      • Weifen Li

    • PubMed: 20181878
    • DOI: 10.3382/ps.2009-00319

    12 Insights on

    • Increased Body Weight
    • Improved Growth Performance
    • Improved Cell Survival Rates
    • Improved Shear Force of Meat
    • Reduced Drip Loss in Meat
    • Reduced Drip Loss
    • Increased Survival Rate
    • No Significant Change in Breast Composition
    • Maintained pH Levels
    • Increased Shear Force
    • Reduced Shear Force
    • Altered Breast Chemical Composition

    • High evidence
    • Highly Cited
    • Rigorous Journal

  • Dietary supplementation with lactobacilli and bifidobacteria is well tolerated and not associated with adverse events during late pregnancy and early infancy.

    • 2010-03
    • RCT · n = 462
    • The Journal of Nutrition 140(3)
    • • Stephen J Allen
      • S. Jordan
      • M. Storey
      • C. Thornton
      • M. Gravenor
      • I. Garaiová
      • S. Plummer
      • Duolao Wang
      • G. Morgan

    • PubMed: 20089774
    • DOI: 10.3945/jn.109.117093

    3 Insights on

    • Reduced Incidence of Adverse Events
    • Increased Adverse Events
    • Increased Safety in Vulnerable Populations

    • High evidence
    • Large Human Trial
    • Highly Cited