February 2015 Supplement Research Papers

• February 10

  • Relationships between the genome and some phenotypical properties of Lactobacillus fermentum CECT 5716, a probiotic strain isolated from human milk

    • 2015-02-10
    • Applied Microbiology and Biotechnology 99(10)
    • • Nívia Cárdenas
      • J. Laiño
      • S. Delgado
      • E. Jiménez
      • Marianela Juárez del Valle
      • Graciela Savoy De Giori
      • F. Sesma
      • B. Mayo
      • L. Fernández
      • J. G. LeBlanc
      • J. M. Rodríguez

    • PubMed: 25661998
    • DOI: 10.1007/s00253-015-6429-0

    7 Insights on

    • Reduced Inflammation Levels
    • Improved Immunomodulation
    • Reduced Total Infections
    • Enhanced Phenotypic Maturation of Dendritic Cells
    • Reduced Infection Rate
    • Enhanced Anti-Infective Properties
    • Increased Maturation of Mouse Dendritic Cells

    • Low evidence
• February 12

  • Safety Characterization and Antimicrobial Properties of Kefir-Isolated Lactobacillus kefiri

    • 2015-02-12
    • Clinical Trial
    • BioMed Research International 2014
    • • P. Carasi
      • M. Díaz
      • S. Racedo
      • G. D. De Antoni
      • M. Urdaci
      • M. Serradell

    • PubMed: 24955346
    • DOI: 10.1155/2014/208974

    6 Insights on

    • Reduced Abdominal Pain
    • Non-Translocation to Blood or Organs
    • Absence of Adverse Effects
    • Stable Proinflammatory Cytokine Levels
    • Absence of Microbial Translocation
    • No Change in Proinflammatory Cytokine Secretion

    • Low evidence
    • Animal Study
• February 16

  • Long-term safety of early consumption of Lactobacillus fermentum CECT5716: A 3-year follow-up of a randomized controlled trial.

    • 2015-02-16
    • RCT
    • Pharmacological research 95
    • • J A Maldonado-Lobón
      • M Gil-Campos
      • J Maldonado
      • E López-Huertas
      • K Flores-Rojas
      • A D Valero
      • M V Rodríguez-Benítez
      • O Bañuelos
      • F Lara-Villoslada
      • J Fonollá
      • M Olivares

    • PubMed: 25697549
    • DOI: 10.1016/j.phrs.2015.01.006

    2 Insights on

    • Improved Gut Microbiota Composition
    • Improved Growth in Children

    • High evidence
• February 18

  • Probiotics (Lactobacillus rhamnosus R0011 and acidophilus R0052) reduce the expression of toll-like receptor 4 in mice with alcoholic liver disease.

    • 2015-02-18
    • PloS one 10(2)
    • • Meegun Hong
      • Seung Woo Kim
      • Sang Hak Han
      • Dong Joon Kim
      • Ki Tae Suk
      • Yeon Soo Kim
      • Myong Jo Kim
      • Moon Young Kim
      • Soon Koo Baik
      • Young Lim Ham

    • PubMed: 25692549
    • DOI: 10.1371/journal.pone.0117451

    2 Insights on

    • Reduced Pro-Inflammatory Cytokines
    • Increased Anti-Inflammatory Cytokine IL-10

    • Low evidence
    • Animal Study
• February 26

  • A17, the First Sequenced Strain of Lactococcus lactis subsp. cremoris with Potential Immunomodulatory Functions

    • 2015-02-26
    • Genome Announcements 3(1)
    • • Chih-Hsien Yang
      • Chien-Chen Wu
      • Wei-Shen Cheng
      • Ming-Chuan Chung
      • Y. Tsai
      • Chuan-Hsiung Chang

    • PubMed: 25676767
    • DOI: 10.1128/genomeA.01563-14

    2 Insights on

    • Improved Immunomodulation
    • Improved Antiallergic Function

    • Low evidence
• February 27

  • Salacia reticulata (Kothala himbutu) revisited; a missed opportunity to treat diabetes and obesity?

    • 2015-02-27
    • Review
    • Nutrition journal 14
    • • Arjuna B Medagama

    • PubMed: 25889885
    • DOI: 10.1186/s12937-015-0013-4

    5 Insights on

    • Reduced Body Mass Index
    • Reduced Body Weight
    • Reduced Insulin Levels
    • Reduced Hemoglobin A1c
    • Reduced Fasting Blood Glucose Levels

    • Low evidence
• Undated – 2 supplement studies

  • The effects of Lactobacillus acidophilus as feed supplement on skin mucosal immune parameters, intestinal microbiota, stress resistance and growth performance of black swordtail (Xiphophorus helleri).

    • 2015-02
    • RCT
    • Fish & Shellfish Immunology 42(2)
    • • S. Hoseinifar
      • Z. Roosta
      • A. Hajimoradloo
      • F. Vakili

    • PubMed: 25514375
    • DOI: 10.1016/j.fsi.2014.12.003

    21 Insights on

    • Improved Gut Microbiota
    • Improved Antibacterial Activity
    • Improved Growth Performance
    • Increased Skin Mucus Protein Levels
    • Improved Salinity Stress Resistance
    • Enhanced Skin Mucosal Immune Parameters
    • Improved Weight Gain
    • Enhanced Mucosal Immune Function
    • Enhanced Alkaline Phosphatase Activity
    • Increased Skin Mucus Antibacterial Activity
    • Increased Levels of Autochthonous Intestinal Bacteria
    • Improved Growth
    • Elevated Alkaline Phosphatase Levels
    • Increased Endogenous Bacteria
    • Increased Autochthonous Lactic Acid Bacteria Levels
    • Increased Alkaline Phosphatase Activity in Skin Mucus
    • Improved Specific Growth Rate
    • Enhanced Stress Resistance
    • Improved Antibacterial Activity in Skin Mucus
    • Increased Autochthonous Bacteria Levels
    • Increased Salinity Stress Resistance (Survival Percentage)

    • High evidence
    • Highly Cited

  • A randomized clinical trial of Saccharomyces cerevisiae versus placebo in the irritable bowel syndrome.

    • 2015-02
    • RCT · n = 179
    • Digestive and Liver Disease 47(2)
    • • G. Pineton de Chambrun
      • C. Neut
      • A. Chau
      • M. Cazaubiel
      • Fanny Pélerin
      • Peter Justen
      • P. Desreumaux

    • PubMed: 25488056
    • DOI: 10.1016/j.dld.2014.11.007

    2 Insights on

    • Reduced Abdominal Pain Severity
    • Improved Tolerance to Saccharomyces cerevisiae

    • High evidence
    • Highly Cited