January 2015 Supplement Research Papers

• January 1

  • Evaluation of Bacillus subtilis R0179 on gastrointestinal viability and general wellness: a randomised, double-blind, placebo-controlled trial in healthy adults.

    • 2015-01-01
    • RCT · n = 81
    • Beneficial Microbes 6(1)
    • • A. Hanifi
      • T. Culpepper
      • Volker Mai
      • Anshu Anand
      • A. Ford
      • M. Ukhanova
      • M. Christman
      • Thomas A. Tompkins
      • Wendy J. Dahl

    • PubMed: 25062611
    • DOI: 10.3920/BM2014.0031

    5 Insights on

    • Reduced Gastrointestinal Symptoms
    • Improved Intestinal Function
    • Maintained General Health
    • Improved Gastrointestinal Viability
    • Enhanced General Wellness

    • High evidence

  • Preventive effects of oral probiotic on infantile colic: a prospective, randomised, blinded, controlled trial using Lactobacillus reuteri DSM 17938.

    • 2015-01-01
    • RCT · n = 138
    • Beneficial microbes 6(3)
    • • F Savino
      • S Ceratto
      • E Poggi
      • M E Cartosio
      • L Cordero di Montezemolo
      • A Giannattasio

    • PubMed: 25488262
    • DOI: 10.3920/bm2014.0090

    4 Insights on

    • Reduced Abdominal Pain
    • Reduced Simethicone Use
    • Reduced Infant Formula Switching
    • Reduced Infantile Colic Consultation

    • High evidence
    • Large Human Trial
    • Rigorous Journal

  • Safety and efficacy of human breast milk Lactobacillus fermentum CECT 5716. A mini-review of studies with infant formulae.

    • 2015-01-01
    • Review
    • Beneficial Microbes 6(2)
    • • E. López-Huertas

    • PubMed: 25519525
    • DOI: 10.3920/BM2014.0091

    1 Insight on

    • Reduced Community-Acquired Infection Incidence

    • Low evidence

  • Bifidobacterium infantis has a beneficial effect on 5-fluorouracil-induced intestinal mucositis in rats.

    • 2015-01-01
    • RCT · n = 30
    • Beneficial Microbes 6(1)
    • • Kai-Tao Yuan
      • Honglan Yu
      • W. Feng
      • P. Chong
      • T. Yang
      • Conglong Xue
      • M. Yu
      • Houyin Shi

    • PubMed: 25380796
    • DOI: 10.3920/BM2013.0095

    4 Insights on

    • Increased Body Weight
    • Reduced Inflammatory Markers
    • Increased Villus Height
    • Reduced Myeloperoxidase (MPO) Concentration

    • Low evidence
    • Animal Study

  • The effect of Lactobacillus paracasei subsp. paracasei L. casei W8® on blood levels of triacylglycerol is independent of colonisation.

    • 2015-01-01
    • RCT · n = 64
    • Beneficial Microbes 6(3)
    • • A. T. Bjerg
      • M. Sørensen
      • L. Krych
      • L. Hansen
      • A. Astrup
      • M. Kristensen
      • D. Nielsen

    • PubMed: 25273547
    • DOI: 10.3920/BM2014.0033

    2 Insights on

    • Reduced Triglyceride Levels
    • Reduced Serum Triacylglycerols

    • High evidence

  • Four weeks supplementation with Lactobacillus paracasei subsp. paracasei L. casei W8® shows modest effect on triacylglycerol in young healthy adults.

    • 2015-01-01
    • RCT · n = 80
    • Beneficial Microbes 6(1)
    • • A. T. Bjerg
      • Mette Kristensen
      • Christian Ritz
      • Ken D. Stark
      • J. J. Holst
      • T. Leser
      • Anja Wellejus
      • Arne Astrup

    • PubMed: 25245572
    • DOI: 10.3920/BM2014.0058

    5 Insights on

    • Reduced Triglyceride Levels
    • Reduced Serum Triacylglycerols
    • No Change in Appetite Parameters
    • Stable Appetite Parameters
    • Reduced SCD1 Activity

    • High evidence
• January 2

  • Lactobacillus acidophilus ATCC 4356 inhibits biofilm formation by C. albicans and attenuates the experimental candidiasis in Galleria mellonella

    • 2015-01-02
    • Virulence 6(1)
    • • S. F. Vilela
      • J. Barbosa
      • R. D. Rossoni
      • J. D. Santos
      • M. C. A. Prata
      • A. Anbinder
      • A. O. Jorge
      • J. C. Junqueira

    • PubMed: 25654408
    • DOI: 10.4161/21505594.2014.981486

    2 Insights on

    • Reduced Candida albicans Colony-Forming Units
    • Increased Survival Rate During Candidiasis

    • Low evidence
    • Highly Cited

  • Changes in bile acids, FGF-19 and sterol absorption in response to bile salt hydrolase active L. reuteri NCIMB 30242

    • 2015-01-02
    • RCT · n = 14
    • Gut Microbes 6(1)
    • • C. Martoni
      • A. Labbé
      • J. Ganopolsky
      • S. Prakash
      • M. Jones

    • PubMed: 25612224
    • DOI: 10.1080/19490976.2015.1005474

    8 Insights on

    • Increased Total Bile Acid Levels
    • Increased Conjugated Bile Acid Levels
    • Increased Unconjugated Bile Acid Levels
    • Increased Circulating Bile Acid Levels
    • Increased Total Bile Acids
    • Increased Unconjugated Bile Acids
    • Potential Modulation of FGF-19 Levels
    • Reduced Plant Sterols

    • High evidence
    • Rigorous Journal

  • Safety of Bifidobacterium animalis subsp. lactis (B. lactis) strain BB-12-supplemented yogurt in healthy adults on antibiotics: a phase I safety study

    • 2015-01-02
    • RCT · n = 40
    • Gut Microbes 6(1)
    • • D. Merenstein
      • T. Tan
      • Aleksey Molokin
      • K. H. Smith
      • R. Roberts
      • N. Shara
      • M. Mete
      • M. Sanders
      • G. Solano-Aguilar

    • PubMed: 25569274
    • DOI: 10.1080/19490976.2015.1005484

    5 Insights on

    • Increased Probiotic B. lactis Levels
    • Increased Fecal Bifidobacterium lactis Levels
    • Altered Expression of Immune-Related Genes
    • Modulated Immune Markers
    • Increased Immune Marker Activation

    • High evidence
    • Rigorous Journal
• January 9

  • Maternal intake of Natto, a Japan's traditional fermented soybean food, during pregnancy and the risk of eczema in Japanese babies.

    • 2015-01-09
    • Observational · n = 650
    • Allergology International 63(2)
    • • Naoko Ozawa
      • N. Shimojo
      • Yoichi Suzuki
      • Shingo Ochiai
      • T. Nakano
      • Y. Morita
      • Y. Inoue
      • T. Arima
      • Shuichi Suzuki
      • Y. Kohno

    • PubMed: 24759553
    • DOI: 10.2332/allergolint.13-OA-0613

    2 Insights on

    • Reduced Infant Eczema
    • Reduced Eczema Incidence

    • High evidence
• January 21

  • Bifidobacterium bifidum R0071 results in a greater proportion of healthy days and a lower percentage of academically stressed students reporting a day of cold/flu: a randomised, double-blind, placebo-controlled study

    • 2015-01-21
    • RCT · n = 581
    • British Journal of Nutrition 113(3)
    • • B. Langkamp-Henken
      • C. Rowe
      • A. Ford
      • M. Christman
      • C. Nieves
      • Lauren Khouri
      • Gretchen J. Specht
      • S. Girard
      • Samuel J. Spaiser
      • W. Dahl

    • PubMed: 25604727
    • DOI: 10.1017/S0007114514003997

    5 Insights on

    • Improved Proportion of Healthy Days
    • Reduced Incidence of Cold/Flu Days
    • Reduced Cold Symptoms
    • Reduced Cold and Flu Incidence
    • Increased Proportion of Healthy Days

    • High evidence
    • Large Human Trial
• January 25

  • Comparison between three different saliva substitutes in patients with hyposalivation.

    • 2015-01-25
    • RCT · n = 60
    • Clinical oral investigations 19(3)
    • • Ivana Skrinjar
      • Vanja Vucicevic Boras
      • Iva Bakale
      • Ana Andabak Rogulj
      • Vlaho Brailo
      • Danica Vidovic Juras
      • Ivan Alajbeg
      • Danko Velimir Vrdoljak

    • PubMed: 25617026
    • DOI: 10.1007/s00784-015-1405-8

    2 Insights on

    • Improved Quality of Life
    • Reduced Dry Mouth Intensity

    • High evidence
• Undated – 5 supplement studies

  • Probiotics for infantile colic: a randomized, double-blind, placebo-controlled trial investigating Lactobacillus reuteri DSM 17938.

    • 2015-01
    • RCT · n = 52
    • The Journal of Pediatrics 166(1)
    • • Kim Chau
      • E. Lau
      • S. Greenberg
      • S. Jacobson
      • Parvaneh Yazdani-Brojeni
      • Natasha A. Verma
      • G. Koren

    • PubMed: 25444531
    • DOI: 10.1016/j.jpeds.2014.09.020

    1 Insight on

    • Reduced Crying Time

    • High evidence
    • Highly Cited

  • The effects of combined dietary probiotics Lactococcus lactis BFE920 and Lactobacillus plantarum FGL0001 on innate immunity and disease resistance in olive flounder (Paralichthys olivaceus).

    • 2015-01
    • Fish & Shellfish Immunology 42(1)
    • • B. Beck
      • Daniel Kim
      • Jongsu Jeon
      • Sun-Min Lee
      • H. K. Kim
      • Oi-Jin Kim
      • Jae Il Lee
      • B. Suh
      • H. Do
      • K. Lee
      • W. Holzapfel
      • J. Hwang
      • M. Kwon
      • S. Song

    • PubMed: 25449382
    • DOI: 10.1016/j.fsi.2014.10.035

    7 Insights on

    • Increased PMN Cell Phagocytic Capacity
    • Increased Body Weight
    • Improved Immune Response
    • Improved Innate Immune Response
    • Improved Survival Rate Against Infection
    • Improved Skin Mucus Lysozyme Activity
    • Increased Neutrophil Activity

    • Low evidence
    • Highly Cited

  • Consecutive oral administration of Bifidobacterium longum MM‐2 improves the defense system against influenza virus infection by enhancing natural killer cell activity in a murine model

    • 2015-01
    • Clinical Trial
    • Microbiology and Immunology 59(1)
    • • Tomohiro Kawahara
      • Tadanobu Takahashi
      • Kenta Oishi
      • Hiromu Tanaka
      • M. Masuda
      • Shunsaku Takahashi
      • Maiko Takano
      • Tatsuya Kawakami
      • Keijo Fukushima
      • H. Kanazawa
      • Takashi Suzuki

    • PubMed: 25400245
    • DOI: 10.1111/1348-0421.12210

    7 Insights on

    • Enhanced IFN-γ Production
    • Improved Clinical Symptoms of Influenza
    • Reduced Mortality from Influenza Infection
    • Reduced Inflammation in the Lower Respiratory Tract
    • Reduced Virus Titers in Bronchoalveolar Lavage Fluid
    • Improved Splenetic NK Cell Activity
    • Activated Systemic Immunoreactivity in Peyer's Patches

    • Low evidence
    • Highly Cited
    • Animal Study

  • Surface proteins of Propionibacterium freudenreichii are involved in its anti-inflammatory properties.

    • 2015-01
    • Journal of Proteomics 113
    • • C. Le Maréchal
      • V. Péton
      • C. Ple
      • Christophe Vroland
      • J. Jardin
      • V. Briard-Bion
      • G. Durant
      • Victoria Chuat
      • V. Loux
      • B. Foligné
      • S. Deutsch
      • H. Falentin
      • G. Jan

    • PubMed: 25150945
    • DOI: 10.1016/j.jprot.2014.07.018

    2 Insights on

    • Modulated Immune Response
    • Reduced Gut Inflammation

    • Low evidence
    • Highly Cited

  • Complete genome sequence of Lactobacillus helveticus H9, a probiotic strain originated from kurut.

    • 2015-01
    • Journal of Biotechnology 194
    • • Yongfu Chen
      • Wenyi Zhang
      • Zhihong Sun
      • Bilighe Meng
      • Heping Zhang

    • PubMed: 25499075
    • DOI: 10.1016/j.jbiotec.2014.11.038

    2 Insights on

    • Reduced Blood Pressure
    • Increased Antihypertensive Peptide Production

    • Low evidence