July 2016 Supplement Research Papers

• July 6

  • Oral treatment with Eubacterium hallii improves insulin sensitivity in db/db mice

    • 2016-07-06
    • Clinical Trial
    • npj Biofilms and Microbiomes 2(1)
    • • S. Udayappan
      • L. Mannerås-Holm
      • Alice Chaplin-Scott
      • C. Belzer
      • H. Herrema
      • G. Dallinga-Thie
      • S. Duncan
      • E. Stroes
      • A. Groen
      • H. Flint
      • F. Backhed
      • W. D. de Vos
      • M. Nieuwdorp

    • PubMed: 28721246
    • DOI: 10.1038/npjbiofilms.2016.9

    3 Insights on

    • Improved Insulin Sensitivity
    • Increased Fecal Butyric Acid Concentration
    • Increased Energy Expenditure

    • Low evidence
    • Highly Cited
    • Animal Study
• July 21

  • Probiotic Bacillus coagulans GBI-30, 6086 reduces exercise-induced muscle damage and increases recovery

    • 2016-07-21
    • PeerJ 4
    • • R. Jäger
      • Kevin A. Shields
      • Ryan P. Lowery
      • E. D. de Souza
      • Jeremy M Partl
      • Chase A Hollmer
      • M. Purpura
      • Jacob M. Wilson

    • PubMed: 27547577
    • DOI: 10.7717/peerj.2276

    4 Insights on

    • Maintained Physical Performance
    • Reduced Muscle Soreness
    • Improved Recovery Rate
    • Reduced Muscle Damage

    • Moderate evidence
    • Highly Cited
    • Rigorous Journal
• July 22

  • Dietary supplementation with Bifidobacterium longum subsp. infantis (B. infantis) in healthy breastfed infants: study protocol for a randomised controlled trial

    • 2016-07-22
    • RCT
    • Trials 17(1)
    • • S. Awasthi
      • R. Wilken
      • F. Patel
      • J. German
      • D. Mills
      • C. Lebrilla
      • Kyoung-Youl Kim
      • Samara L. Freeman
      • J. Smilowitz
      • A. Armstrong
      • E. Maverakis

    • PubMed: 27449926
    • DOI: 10.1186/s13063-016-1467-1

    1 Insight on

    • Preventative Gut Colonisation

    • High evidence
• July 28

  • Safety Assessment of Two New Lactobacillus Strains as Probiotic for Human Using a Rat Model

    • 2016-07-28
    • Clinical Trial
    • PLOS ONE 11(7)
    • • P. Shokryazdan
      • Mohammad Faseleh Jahromi
      • J. Liang
      • R. Kalavathy
      • C. C. Sieo
      • Y. Ho

    • PubMed: 27467068
    • DOI: 10.1371/journal.pone.0159851

    3 Insights on

    • Absence of Adverse Effects
    • Increased Beneficial Gut Bacteria
    • Reduced Pathogenic Bacterial Populations

    • Low evidence
    • Rigorous Journal
    • Animal Study
• July 29

  • Lactobacilli Interfere with Streptococcus pyogenes Hemolytic Activity and Adherence to Host Epithelial Cells

    • 2016-07-29
    • Frontiers in Microbiology 7
    • • S. Saroj
      • Lisa Maudsdotter
      • R. Tavares
      • A. Jonsson

    • PubMed: 27524981
    • DOI: 10.3389/fmicb.2016.01176

    1 Insight on

    • Reduced GAS Adherence to Host Epithelial Cells

    • Low evidence
• Undated – 8 supplement studies

  • The effects of feeding with synbiotic (Pediococcus acidilactici and fructooligosaccharide) enriched adult Artemia on skin mucus immune responses, stress resistance, intestinal microbiota and performance of angelfish (Pterophyllum scalare).

    • 2016-07
    • RCT
    • Fish & Shellfish Immunology 54
    • • Mahmood Azimirad
      • S. Meshkini
      • N. Ahmadifard
      • S. Hoseinifar

    • PubMed: 27150050
    • DOI: 10.1016/j.fsi.2016.05.001

    8 Insights on

    • Improved Gut Microbiota
    • Increased Serum Lysozyme Activity
    • Improved Growth Performance
    • Increased Immunoglobulin Levels
    • Increased Skin Mucus Immune Response
    • Enhanced Stress Resistance
    • Increased Fecal Lactic Acid Bacteria Concentration
    • Increased Intestinal Lactic Acid Bacteria Population

    • High evidence
    • Highly Cited

  • Lactobacillus reuteri DSM 17938 for the Management of Functional Abdominal Pain in Childhood: A Randomized, Double-Blind, Placebo-Controlled Trial.

    • 2016-07
    • RCT · n = 101
    • The Journal of Pediatrics 174
    • • Z. Weizman
      • Jaber Abu-Abed
      • M. Binsztok

    • PubMed: 27156182
    • DOI: 10.1016/j.jpeds.2016.04.003

    2 Insights on

    • Reduced Abdominal Pain Frequency
    • Reduced Abdominal Pain Intensity

    • High evidence

  • Lactobacillus helveticus Lafti L10 supplementation reduces respiratory infection duration in a cohort of elite athletes: a randomized, double-blind, placebo-controlled trial.

    • 2016-07
    • RCT · n = 39
    • Applied Physiology, Nutrition, and Metabolism 41(7)
    • • D. Michaličková
      • R. Minić
      • N. Dikić
      • M. Andjelkovic
      • Marija Kostic-Vucicevic
      • Tamara Stojmenovic
      • Ivan Nikolić
      • B. Djordjevic

    • PubMed: 27363733
    • DOI: 10.1139/apnm-2015-0541

    10 Insights on

    • Reduced URTI Symptoms
    • Reduced Duration of Upper Respiratory Tract Infection
    • Reduced Duration of Upper Respiratory Tract Illness
    • Reduced Upper Respiratory Tract Infection Symptoms
    • Unchanged Severity of URTI
    • Increased CD4+/CD8+ Ratio
    • Improved Self-Rated Vigor
    • Improved CD4+/CD8+ Ratio
    • Reduced URTI Duration
    • Altered CD4+/CD8+ Ratio

    • High evidence

  • Effects of synbiotic fermented milk containing Lactobacillus acidophilus La-5 and Bifidobacterium animalis ssp. lactis BB-12 on the fecal microbiota of adults with irritable bowel syndrome: A randomized double-blind, placebo-controlled trial.

    • 2016-07
    • RCT · n = 30
    • Journal of Dairy Science 99(7)
    • • B. Bogovič Matijašić
      • T. Obermajer
      • L. Lipoglavšek
      • Tjaša Sernel
      • I. Locatelli
      • Mitja Kos
      • A. Šmid
      • I. Rogelj

    • PubMed: 27157575
    • DOI: 10.3168/jds.2015-10743

    1 Insight on

    • Presence of Viable L. acidophilus La-5 Strains in Feces

    • High evidence
    • Rigorous Journal

  • Efficacy of prolonged ingestion of Lactobacillus acidophilus L-92 in adult patients with atopic dermatitis.

    • 2016-07
    • RCT · n = 50
    • Journal of Dairy Science 99(7)
    • • Kozo Yamamoto
      • K. Yokoyama
      • Takehisa Matsukawa
      • Sayaka Kato
      • S. Kato
      • Kazuhisa Yamada
      • Tatsuhiko Hirota

    • PubMed: 27108169
    • DOI: 10.3168/jds.2015-10605

    18 Insights on

    • Improved Immune Function
    • Improved Skin Symptoms
    • Reduced Subjective Symptoms
    • Reduced Lactate Dehydrogenase Levels
    • Increased Transforming Growth Factor-β Levels
    • Increased IL-12 Levels
    • Reduced Type-2-helper-T-cell-dominant Inflammation
    • Improved Atopic Dermatitis Symptoms
    • Improved Atopic Dermatitis Severity
    • Increased Interleukin-12 Production
    • Reduced Atopic Dermatitis Severity
    • Reduced Scratching Frequency
    • Reduced Lactate Dehydrogenase Level
    • Reduced Eczema Area and Severity Index
    • Reduced Investigator Global Assessment
    • Reduced Atopic Dermatitis Severity Score
    • Reduced Scratching Behavior
    • Maintained Remission of Skin Symptoms

    • High evidence
    • Rigorous Journal

  • Lactobacillus crispatus as biomarker of the healthy vaginal tract.

    • 2016-07
    • Annales de biologie clinique 74(4)
    • • J. Lepargneur

    • PubMed: 27492695
    • DOI: 10.1684/abc.2016.1169

    2 Insights on

    • Improved Vaginal Health
    • Enhanced Vaginal Health

    • Low evidence

  • Effect of oral administration of Bacillus coagulans B37 and Bacillus pumilus B9 strains on fecal coliforms, Lactobacillus and Bacillus spp. in rat animal model

    • 2016-07
    • RCT · n = 36
    • Veterinary World 9(7)
    • • Lopamudra Haldar
      • D. N. Gandhi

    • PubMed: 27536040
    • DOI: 10.14202/vetworld.2016.766-772

    4 Insights on

    • Increased Fecal Lactobacilli
    • Reduced Coliform Counts
    • Increased Bacillus Spore Counts
    • Reduced Fecal Coliform Count

    • Low evidence
    • Animal Study

  • Intestinal Microbiota in Pediatric Surgical Cases Administered Bifidobacterium Breve: A Randomized Controlled Trial

    • 2016-07
    • RCT
    • Journal of Pediatric Gastroenterology and Nutrition 63(1)
    • • T. Okazaki
      • T. Asahara
      • A. Yamataka
      • Yuki Ogasawara
      • Geoffrey J. Lane
      • K. Nomoto
      • S. Nagata
      • Y. Yamashiro

    • PubMed: 26859092
    • DOI: 10.1097/MPG.0000000000001140

    25 Insights on

    • Reduced Faecal pH
    • Reduced Enterobacteriaceae Counts
    • Increased Acetic Acid Levels in Feces
    • Reduced Postoperative Infectious Complications
    • Elevated Bifidobacterium Levels
    • Increased Fecal Acetic Acid Concentration
    • Reduced Blood Bacterial Incidence
    • Increased Fecal Bifidobacteria Levels
    • Increased Intestinal Bifidobacteria Levels
    • Reduced Clostridium difficile Count
    • Improved Intestinal Microenvironment
    • Improved Intestinal Health
    • Reduced Pseudomonas in Feces
    • Reduced Enterobacteriaceae Levels in Feces
    • Increased Intestinal Bifidobacteria Population
    • Reduced Bacterial Load in Blood
    • Reduced Bacteremia
    • Increased Bifidobacterium Levels
    • Reduced Bacteremia Incidence
    • Reduced Enterobacteriaceae in Intestines
    • Reduced Clostridium Difficile in Intestines
    • Reduced Bacterial Detection in Blood
    • Reduced Fecal Clostridium difficile
    • Reduced Bacterial Levels in Blood
    • Reduced Clostridium Difficile Levels

    • High evidence