June 2010 Supplement Research Papers

• June 1

  • Synbiotic effects of lactitol and Lactobacillus acidophilus NCFM™ in a semi-continuous colon fermentation model.

    • 2010-06-01
    • Beneficial Microbes 1(2)
    • • H. Mäkivuokko
      • S. Forssten
      • M. Saarinen
      • A. Ouwehand
      • N. Rautonen

    • PubMed: 21840801
    • DOI: 10.3920/BM2009.0033

    3 Insights on

    • Increased Butyrate Production
    • Reduced Clostridia Cluster XIV
    • Increased Propionic Acid Production

    • Low evidence
• June 2

  • Caries Inhibition by and Safety of Lactobacillus paracasei DSMZ16671

    • 2010-06-02
    • RCT
    • Journal of Dental Research 89(9)
    • • J. Tanzer
      • A. Thompson
      • C. Lang
      • B. Cooper
      • L. Hareng
      • A. Gamer
      • A. Reindl
      • M. Pompejus

    • PubMed: 20519491
    • DOI: 10.1177/0022034510369460

    5 Insights on

    • Reduced Caries Lesions
    • Reduced Caries Risk
    • No Mutagenicity, Teratogenicity, or Genotoxicity
    • Reduced Streptococcus mutans Recoveries
    • Absence of Toxicity

    • Low evidence
    • Animal Study
• June 15

  • Treatment of infectious mastitis during lactation: antibiotics versus oral administration of Lactobacilli isolated from breast milk.

    • 2010-06-15
    • RCT · n = 352
    • Clinical Infectious Diseases 50(12)
    • • Rebeca Arroyo
      • V. Martín
      • Antonio Maldonado
      • E. Jiménez
      • L. Fernández
      • J. M. Rodríguez

    • PubMed: 20455694
    • DOI: 10.1086/652763

    2 Insights on

    • Reduced Milk Bacterial Counts
    • Improved Mastitis Symptoms

    • High evidence
    • Large Human Trial
    • Highly Cited
• June 30

  • Immunomodulatory activity of Lactobacillus rhamnosus strains isolated from goat milk: impact on intestinal and respiratory infections.

    • 2010-06-30
    • Clinical Trial
    • International Journal of Food Microbiology 141(1-2)
    • • S. Salva
      • J. Villena
      • S. Alvarez

    • PubMed: 20395002
    • DOI: 10.1016/j.ijfoodmicro.2010.03.013

    10 Insights on

    • Enhanced Mucosal Immune Response
    • Improved Resistance to Foodborne Pathogens
    • Enhanced Resistance to Streptococcus Pneumoniae Infection
    • Improved Intestinal Resistance to Salmonella Typhimurium
    • Reduced Streptococcus pneumoniae in Lung
    • Enhanced Resistance to Respiratory Infections
    • Neutral Effect on Respiratory Infections Caused by Streptococcus Pneumoniae
    • Improved Resistance to Intestinal Pathogens
    • Reduced Respiratory Pathogen Load
    • Prevention of Bloodstream Pathogen Dissemination

    • Low evidence
    • Highly Cited
    • Animal Study
• Undated – 3 supplement studies

  • Regulation of human epithelial tight junction proteins by Lactobacillus plantarum in vivo and protective effects on the epithelial barrier.

    • 2010-06
    • RCT
    • American Journal of Physiology-Gastrointestinal and Liver Physiology 298(6)
    • • J. Karczewski
      • F. Troost
      • I. Konings
      • J. Dekker
      • M. Kleerebezem
      • R. Brummer
      • J. Wells

    • PubMed: 20224007
    • DOI: 10.1152/ajpgi.00327.2009

    9 Insights on

    • Improved Intestinal Barrier Function
    • Increased Tight Junction Protein Levels
    • Improved Epithelial Permeability
    • Improved Epithelial Barrier Function
    • Improved Tight Junction Protein Localization
    • Reduced Epithelial Permeability
    • Improved Epithelial Integrity
    • Improved Intestinal Epithelial Barrier Function
    • Reduced Epithelial Barrier Disruption

    • High evidence
    • Highly Cited

  • Lactobacillus GG in the prevention of gastrointestinal and respiratory tract infections in children who attend day care centers: a randomized, double-blind, placebo-controlled trial.

    • 2010-06
    • RCT · n = 281
    • Clinical Nutrition 29(3)
    • • I. Hojsak
      • Natalija Snovak
      • S. Abdovic
      • H. Szajewska
      • Z. Mišak
      • S. Kolaček

    • PubMed: 19896252
    • DOI: 10.1016/j.clnu.2009.09.008

    10 Insights on

    • Reduced Vomiting Frequency
    • Reduced Incidence of Upper Respiratory Tract Infections
    • Reduced Respiratory Symptoms
    • Reduced Diarrhea Episodes
    • Reduced Duration of Upper Respiratory Tract Infection
    • Reduced Respiratory Symptom Days
    • Reduced Risk of Prolonged Respiratory Infections
    • No Significant Reduction in Lower Respiratory Tract Infections
    • No Reduction in Gastrointestinal Infections
    • No Significant Change in Duration of Gastrointestinal Symptoms

    • High evidence
    • Highly Cited

  • Intestinal and immunological effects of daily oral administration of Lactobacillus salivarius CECT5713 to healthy adults.

    • 2010-06
    • RCT · n = 40
    • Anaerobe 16(3)
    • • S. Sierra
      • F. Lara‐Villoslada
      • Lluis Sempere
      • M. Olivares
      • J. Boza
      • J. Xaus

    • PubMed: 20159049
    • DOI: 10.1016/j.anaerobe.2010.02.001

    7 Insights on

    • Improved Gut Microbiota
    • Improved Bowel Movement Frequency
    • Increased Fecal Lactobacilli
    • Improved Immune Response
    • Increased Interleukin-10 Levels
    • No Reported Adverse Effects
    • Increased Plasma Immunoglobulin Levels

    • High evidence
    • Highly Cited