May 2012 Supplement Research Papers

• May 1

  • Randomized Trial of Probiotics and Calcium on Diarrhea and Respiratory Tract Infections in Indonesian Children

    • 2012-05-01
    • RCT · n = 494
    • Pediatrics 129(5)
    • • R. Agustina
      • F. Kok
      • O. van de Rest
      • U. Fahmida
      • A. Firmansyah
      • W. Lukito
      • E. Feskens
      • E. G. van den Heuvel
      • R. Albers
      • I. Bovee-Oudenhoven

    • PubMed: 22492764
    • DOI: 10.1542/peds.2011-1379

    1 Insight on

    • Reduced Diarrhea Incidence

    • High evidence
    • Large Human Trial
    • Highly Cited
• May 23

  • Enhanced Immunomodulatory Activity and Stability in Simulated Digestive Juices of Lactobacillus plantarum L-137 by Heat Treatment

    • 2012-05-23
    • Bioscience, Biotechnology, and Biochemistry 76(5)
    • • Takashi Fujiki
      • Y. Hirose
      • Yoshihiro Yamamoto
      • S. Murosaki

    • PubMed: 22738959
    • DOI: 10.1271/bbb.110919

    2 Insights on

    • Improved Cytokine Production
    • Protection Against Colitis

    • Low evidence
• May 28

  • Which characteristic of Natto: appearance, odor, or taste most affects preference for Natto

    • 2012-05-28
    • Clinical Trial
    • Journal of Physiological Anthropology 31(1)
    • • Yu Tsumura
      • Aki Ohyane
      • K. Yamashita
      • Y. Sone

    • PubMed: 22738664
    • DOI: 10.1186/1880-6805-31-13

    2 Insights on

    • Improved Digestibility
    • Reduced Blood Clot Formation

    • High evidence
    • Rigorous Journal
• May 31

  • A randomised study on the effects of fish protein supplement on glucose tolerance, lipids and body composition in overweight adults.

    • 2012-05-31
    • RCT
    • The British journal of nutrition 109(4)
    • • Linn A Vikøren
      • Ottar K Nygård
      • Einar Lied
      • Espen Rostrup
      • Oddrun A Gudbrandsen

    • PubMed: 22647247
    • DOI: 10.1017/s0007114512001717

    7 Insights on

    • Reduced Body Fat Percentage
    • Improved Insulin Levels
    • Reduced LDL Cholesterol
    • Reduced Postprandial Glucose
    • Reduced Fasting Glucose
    • Reduced Glucose Area Under the Curve
    • Increased Body Muscle Percentage

    • High evidence
• Undated – 5 supplement studies

  • Effects of potential probiotic Bacillus subtilis T13 on growth, immunity and disease resistance against Vibrio splendidus infection in juvenile sea cucumber Apostichopus japonicus.

    • 2012-05
    • Clinical Trial · n = 30
    • Fish & Shellfish Immunology 32(5)
    • • Yancui Zhao
      • Wenbing Zhang
      • Wei Xu
      • K. Mai
      • Yanjiao Zhang
      • Zhiguo Liufu

    • PubMed: 22342649
    • DOI: 10.1016/j.fsi.2012.01.027

    7 Insights on

    • Increased Superoxide Dismutase Activity
    • Improved Growth Rate
    • Increased Respiratory Burst Activity
    • Improved Phagocytosis
    • Increased Total Coelomocyte Count
    • Increased Nitric Oxide Synthase Activity
    • Reduced Cumulative Mortality After Infection

    • Low evidence
    • Highly Cited
    • Animal Study

  • Contrasting effects of Bifidobacterium breve NCIMB 702258 and Bifidobacterium breve DPC 6330 on the composition of murine brain fatty acids and gut microbiota.

    • 2012-05
    • The American Journal of Clinical Nutrition 95(5)
    • • R. Wall
      • T. Marques
      • Ó. O’Sullivan
      • R. Ross
      • F. Shanahan
      • E. Quigley
      • T. Dinan
      • B. Kiely
      • G. Fitzgerald
      • P. Cotter
      • F. Fouhy
      • F. Fouhy
      • C. Stanton

    • PubMed: 22492373
    • DOI: 10.3945/ajcn.111.026435

    2 Insights on

    • Increased Fecal Propionic Acid Levels
    • Increased Visceral Fat Mass

    • High evidence
    • Highly Cited

  • Efficacy of daily intake of Lactobacillus casei Shirota on respiratory symptoms and influenza vaccination immune response: a randomized, double-blind, placebo-controlled trial in healthy elderly nursing home residents.

    • 2012-05
    • RCT · n = 737
    • The American Journal of Clinical Nutrition 95(5)
    • • Karolien Van Puyenbroeck
      • N. Hens
      • S. Coenen
      • B. Michiels
      • Caroline Beunckens
      • G. Molenberghs
      • P. Van Royen
      • V. Verhoeven

    • PubMed: 22440853
    • DOI: 10.3945/ajcn.111.026831

    2 Insights on

    • Improved Immune Response to Influenza Vaccination
    • Reduced Respiratory Symptoms

    • High evidence
    • Large Human Trial
    • Highly Cited

  • Effects of administration of Bifidobacterium animalis subsp. lactis GCL2505 on defecation frequency and bifidobacterial microbiota composition in humans.

    • 2012-05
    • RCT · n = 17
    • Journal of Bioscience and Bioengineering 113(5)
    • • Akihiro Ishizuka
      • K. Tomizuka
      • Ryo Aoki
      • Tomohiko Nishijima
      • Yasuo Saito
      • R. Inoue
      • K. Ushida
      • Takashi Mawatari
      • Takayuki Ikeda

    • PubMed: 22284965
    • DOI: 10.1016/j.jbiosc.2011.12.016

    21 Insights on

    • Improved Bowel Movement Frequency
    • Increased Bifidobacteria Levels
    • Successful Gastrointestinal Tract Colonization
    • Relieved Constipation
    • Increased Intestinal Bifidobacteria Levels
    • Increased Fecal Bifidobacteria
    • Increased Levels of Bifidobacteria
    • Increased Probiotic B. lactis Levels
    • No Change in Endogenous Bifidobacteria Levels
    • Increased Bifidobacteria Growth
    • Increased Intestinal Bifidobacterium Levels
    • Increased Intestinal Bifidobacteria Population
    • Increased Defecation Frequency
    • Improved Constipation
    • Increased Bacterial Proliferation
    • Preserved Endogenous Bifidobacteria Composition
    • Increased Bifidobacteria Levels in Intestine
    • Increased Proliferation of Administered Bifidobacteria
    • Increased Bifidobacterium lactis GCL2505 Intestinal Proliferation
    • No Change in Endogenous Bifidobacteria Species
    • Increased Bifidobacterium lactis Proliferation in the Intestine

    • High evidence

  • Gut Balance, a synbiotic supplement, increases fecal Lactobacillus paracasei but has little effect on immunity in healthy physically active individuals

    • 2012-05
    • RCT · n = 22
    • Gut Microbes 3(3)
    • • N. West
      • D. Pyne
      • A. Cripps
      • C. Christophersen
      • M. Conlon
      • P. Fricker

    • PubMed: 22572834
    • DOI: 10.4161/gmic.19579

    3 Insights on

    • Increased Fecal Lactobacillus Paracasei Levels
    • Reduced Serum IL-16 Levels
    • No Substantial Effect on Fecal SCFA

    • High evidence