April 2014 Supplement Research Papers

• April 1

  • Effect of Lactobacillus plantarum on diarrhea and intestinal barrier function of young piglets challenged with enterotoxigenic Escherichia coli K88.

    • 2014-04-01
    • Journal of Animal Science 92(4)
    • • K. M. Yang
      • Zong-yong Jiang
      • C. Zheng
      • Li Wang
      • X. Yang

    • PubMed: 24492550
    • DOI: 10.2527/jas.2013-6619

    6 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Diarrhea Incidence
    • Improved Intestinal Morphology
    • Improved Growth Performance
    • Improved Weight Gain
    • Unchanged Intestinal Morphology

    • Moderate evidence
    • Highly Cited
    • Rigorous Journal

  • Diarrhea in Preschool Children and Lactobacillus reuteri: A Randomized Controlled Trial

    • 2014-04-01
    • RCT · n = 336
    • Pediatrics 133(4)
    • • P. Gutiérrez-Castrellón
      • G. López-Velázquez
      • Luisa Díaz-García
      • C. Jiménez-Gutiérrez
      • J. Mancilla-Ramírez
      • Juliana Estevez-Jiménez
      • M. Parra

    • PubMed: 24639271
    • DOI: 10.1542/peds.2013-0652

    20 Insights on

    • Reduced Duration of Diarrhea
    • Reduced Diarrhea Incidence
    • Reduced Diarrhea Rate
    • Reduced Diarrhea Frequency
    • Reduced Antibiotic Usage
    • Reduced Frequency of Upper Respiratory Tract Infections
    • Reduced School Absenteeism Due to Infectious Diseases
    • Reduced Doctor Visits
    • Reduced Healthcare Costs
    • Reduced Duration of Respiratory Tract Infections
    • Reduced Parental Absenteeism from Work
    • Reduced Community Healthcare Costs
    • Reduced Respiratory Tract Infection Episodes
    • Reduced Antibiotic Use
    • Reduced Diarrhea Duration
    • Reduced Respiratory Tract Infection Episode
    • Reduced Duration of Respiratory Tract Infection Episode
    • Reduced Number of Doctor Visits
    • Reduced Day School Absenteeism
    • Reduced Cost

    • High evidence
    • Large Human Trial
    • Highly Cited
• April 10

  • Oral administration of Lactobacillus gasseri SBT2055 is effective for preventing influenza in mice

    • 2014-04-10
    • Clinical Trial
    • Scientific Reports 4(1)
    • • Yosuke Nakayama
      • Tomohiro Moriya
      • F. Sakai
      • N. Ikeda
      • T. Shiozaki
      • T. Hosoya
      • H. Nakagawa
      • T. Miyazaki

    • PubMed: 24717726
    • DOI: 10.1038/srep04638

    4 Insights on

    • Reduced Body Weight
    • Reduced Interleukin-6 Production
    • Reduced Virus Titer
    • Reduced Total Cells in Bronchoalveolar Lavage Fluid

    • Low evidence
    • Highly Cited
    • Animal Study

  • 454 pyrosequencing reveals changes in the faecal microbiota of adults consuming Lactobacillus casei Zhang.

    • 2014-04-10
    • FEMS Microbiology Ecology 88(3)
    • • Jiachao Zhang
      • Lifeng Wang
      • Zhuang Guo
      • Zhihong Sun
      • Qimu Gesudu
      • L. Kwok
      • Menghebilige
      • Heping Zhang

    • PubMed: 24702028
    • DOI: 10.1111/1574-6941.12328

    1 Insight on

    • Improved Diversity of Gut Microbiota

    • Low evidence
    • Rigorous Journal
• April 14

  • Lactobacillus amylovorus Inhibits the TLR4 Inflammatory Signaling Triggered by Enterotoxigenic Escherichia coli via Modulation of the Negative Regulators and Involvement of TLR2 in Intestinal Caco-2 Cells and Pig Explants

    • 2014-04-14
    • PLoS ONE 9(4)
    • • A. Finamore
      • Marianna Roselli
      • Ambra Imbinto
      • Julie Seeboth
      • I. Oswald
      • E. Mengheri

    • PubMed: 24733511
    • DOI: 10.1371/journal.pone.0094891

    5 Insights on

    • Reduced Pro-Inflammatory Cytokines
    • Reduced Inflammatory Response
    • Reduced Phospho-p65 Translocation
    • Reduced Proinflammatory Signaling
    • Reduced Intestinal Inflammation

    • Moderate evidence
    • Highly Cited
    • Rigorous Journal
• April 15

  • Preventative and therapeutic probiotic use in allergic skin conditions: experimental and clinical findings.

    • 2014-04-15
    • Review
    • BioMed research international 2013
    • • Öner Özdemir
      • Azize Yasemin Göksu Erol

    • PubMed: 24078929
    • DOI: 10.1155/2013/932391

    3 Insights on

    • Improved Skin Symptoms
    • Improved Skin Condition
    • Prevention or Treatment of Allergic Skin Disorders

    • Low evidence
• April 21

  • Whey protein delays gastric emptying and suppresses plasma fatty acids and their metabolites compared to casein, gluten, and fish protein.

    • 2014-04-21
    • RCT
    • Journal of proteome research 13(5)
    • • Jan Stanstrup
      • Simon S Schou
      • Jens Holmer-Jensen
      • Kjeld Hermansen
      • Lars O Dragsted

    • PubMed: 24708224
    • DOI: 10.1021/pr401214w

    2 Insights on

    • Increased Hydroxy Fatty Acid Level
    • Increased Dicarboxylic Fatty Acid Level

    • High evidence
• April 28

  • Double-blind, randomised, placebo-controlled intervention trial to evaluate the effects of Bifidobacterium longum CECT 7347 in children with newly diagnosed coeliac disease

    • 2014-04-28
    • RCT · n = 33
    • British Journal of Nutrition 112(1)
    • • M. Olivares
      • G. Castillejo
      • V. Varea
      • Y. Sanz

    • PubMed: 24774670
    • DOI: 10.1017/S0007114514000609

    6 Insights on

    • Reduced Tumor Necrosis Factor Alpha
    • Improved Height Percentile
    • Decreased Peripheral CD3⁺ T Lymphocyte Count
    • Reduced Bacteroides Fragilis Group Numbers
    • Reduced Secretory IgA Content in Faeces
    • Reduced Secretory Immunoglobulin A in Stools

    • High evidence
    • Highly Cited
• Undated – 4 supplement studies

  • Lactobacillus salivarius WB21--containing tablets for the treatment of oral malodor: a double-blind, randomized, placebo-controlled crossover trial.

    • 2014-04
    • RCT
    • Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 117(4)
    • • N. Suzuki
      • M. Yoneda
      • Kazunari Tanabe
      • A. Fujimoto
      • Kosaku Iha
      • K. Seno
      • Kazuhiko Yamada
      • T. Iwamoto
      • Y. Masuo
      • T. Hirofuji

    • PubMed: 24556493
    • DOI: 10.1016/j.oooo.2013.12.400

    6 Insights on

    • Reduced Ubiquitous Bacteria Levels
    • Reduced Fusobacterium Nucleatum Levels
    • Reduced Oral Malodor
    • Reduced Bacterial Load
    • Reduced Probing Pocket Depth
    • Reduced Probing Depth

    • High evidence

  • Exopolysaccharide-producing Bifidobacterium animalis subsp. lactis strains and their polymers elicit different responses on immune cells from blood and gut associated lymphoid tissue.

    • 2014-04
    • Anaerobe 26
    • • C. Hidalgo-Cantabrana
      • M. Nikolić
      • P. López
      • A. Suárez
      • Marija S. Miljković
      • M. Kojić
      • A. Margolles
      • N. Golić
      • P. Ruas-Madiedo

    • PubMed: 24445155
    • DOI: 10.1016/j.anaerobe.2014.01.003

    3 Insights on

    • Improved Immune System Dialog via EPS
    • Increased Cytokine Production in Peripheral Blood Mononuclear Cells
    • Stable Cytokine Levels in Gut-Associated Lymphoid Tissue

    • Low evidence

  • Lactobacillus sakei modulates mule duck microbiota in ileum and ceca during overfeeding.

    • 2014-04
    • Clinical Trial
    • Poultry Science 93(4)
    • • F. Vasai
      • K. Ricaud
      • L. Cauquil
      • L. Cauquil
      • L. Cauquil
      • P. Daniel
      • C. Peillod
      • Karine Gontier
      • A. Tizaoui
      • Olivier Bouchez
      • Sylvie Combes
      • Sylvie Combes
      • Sylvie Combes
      • S. Davail

    • PubMed: 24706969
    • DOI: 10.3382/ps.2013-03497

    1 Insight on

    • Reduced Richness Indicators in Ileum

    • Low evidence
    • Rigorous Journal
    • Animal Study

  • EFFECT OF Bifidobacterium animalis ON MICE INFECTED WITH Strongyloides venezuelensis

    • 2014-04
    • Clinical Trial
    • Revista do Instituto de Medicina Tropical de São Paulo 56(2)
    • • T. Oliveira-Sequeira
      • É. David
      • C. Ribeiro
      • S. Guimarães
      • A. P. Masseno
      • S. Katagiri
      • J. Sequeira

    • PubMed: 24626410
    • DOI: 10.1590/S0036-46652014000200003

    2 Insights on

    • Reduced Pathogenic Load
    • Improved Intestinal Mucosal Histology

    • Low evidence
    • Animal Study