January 2017 Supplement Research Papers

• January 1

  • Probiotic Lactobacillus reuteri has antifungal effects on oral Candida species in vitro

    • 2017-01-01
    • Journal of Oral Microbiology 9(1)
    • • M. Jørgensen
      • C. Kragelund
      • P. Ø. Jensen
      • M. Keller
      • S. Twetman

    • PubMed: 28326154
    • DOI: 10.1080/20002297.2016.1274582

    2 Insights on

    • Reduced Candida albicans Growth
    • Reduced Candida albicans Aggregation

    • Moderate evidence
    • Highly Cited
    • Rigorous Journal

  • Effect of probiotic supplementation on total lactobacilli, bifidobacteria and short chain fatty acids in 2–5-year-old children

    • 2017-01-01
    • RCT
    • Microbial Ecology in Health and Disease 28(1)
    • • R. Hemalatha
      • A. Ouwehand
      • M. Saarinen
      • U. Prasad
      • K. Swetha
      • V. Bhaskar

    • PubMed: 28572751
    • DOI: 10.1080/16512235.2017.1298340

    2 Insights on

    • Increased Total Bacterial Count
    • Reduced Risk of Diarrhea

    • High evidence
    • Rigorous Journal

  • Effects of passiflora incarnata and midazolam for control of anxiety in patients undergoing dental extraction.

    • 2017-01-01
    • RCT
    • Medicina oral, patologia oral y cirugia bucal 22(1)
    • • L-P Dantas
      • A de Oliveira-Ribeiro
      • L-M de Almeida-Souza
      • F-C Groppo

    • PubMed: 27918731
    • DOI: 10.4317/medoral.21140

    5 Insights on

    • Reduced Blood Pressure
    • Reduced Anxiety
    • Reduced Heart Rate
    • Improved Oxygen Saturation
    • Reduced Amnesia

    • High evidence
• January 3

  • The effects of Lactobacillus plantarum on small intestinal barrier function and mucosal gene transcription; a randomized double-blind placebo controlled trial

    • 2017-01-03
    • RCT · n = 10
    • Scientific Reports 7(1)
    • • Z. Mujagic
      • P. de Vos
      • M. Boekschoten
      • C. Govers
      • Harm-Jan H. M. Pieters
      • N. D. de Wit
      • P. Bron
      • A. Masclee
      • F. Troost

    • PubMed: 28045137
    • DOI: 10.1038/srep40128

    2 Insights on

    • No Significant Effect on Small Intestinal Permeability
    • Enhanced Intestinal Repair Processes

    • High evidence
    • Highly Cited
• January 5

  • Bifidobacterium adolescentis protects against necrotizing enterocolitis and upregulates TOLLIP and SIGIRR in premature neonatal rats

    • 2017-01-05
    • RCT · n = 3
    • BMC Pediatrics 17(1)
    • • Wenshen Wu
      • Yanli Wang
      • Jingjing Zou
      • Fang Long
      • Huiheng Yan
      • L. Zeng
      • Yunbin Chen

    • PubMed: 28056921
    • DOI: 10.1186/s12887-016-0759-7

    3 Insights on

    • Improved Survival Rate
    • Improved Cell Survival Rates
    • Reduced Intestinal Damage

    • Low evidence
    • Rigorous Journal
    • Animal Study
• January 9

  • The Association of Hot Red Chili Pepper Consumption and Mortality: A Large Population-Based Cohort Study

    • 2017-01-09
    • Observational · n = 16,179
    • PLOS ONE 12(1)
    • • Mustafa Chopan
      • B. Littenberg

    • PubMed: 28068423
    • DOI: 10.1371/journal.pone.0169876

    2 Insights on

    • Reduced Cardiovascular Disease Mortality
    • Reduced Overall Mortality Rate

    • High evidence
    • Highly Cited
    • Rigorous Journal
• January 10

  • Dietary Prebiotics and Bioactive Milk Fractions Improve NREM Sleep, Enhance REM Sleep Rebound and Attenuate the Stress-Induced Decrease in Diurnal Temperature and Gut Microbial Alpha Diversity.

    • 2017-01-10
    • Frontiers in behavioral neuroscience 10
    • • Robert S Thompson
      • Rachel Roller
      • Agnieszka Mika
      • Benjamin N Greenwood
      • Rob Knight
      • Maciej Chichlowski
      • Brian M Berg
      • Monika Fleshner

    • PubMed: 28119579
    • DOI: 10.3389/fnbeh.2016.00240

    5 Insights on

    • Improved Sleep Quality
    • Maintained Gut Microbiota Diversity
    • Reduced Stress-Induced Gut Microbial Diversity Loss
    • Improved Diurnal Temperature Rhythm
    • Reduced Stress-Induced Reduction in Diurnal Temperature Amplitude

    • Low evidence
• January 13

  • Lactobacillus rhamnosus GR-1 Attenuates Induction of Hypertrophy in Cardiomyocytes but Not through Secreted Protein MSP-1 (p75)

    • 2017-01-13
    • PLOS ONE 12(1)
    • • G. Ettinger
      • J. Burton
      • G. Gloor
      • G. Reid

    • PubMed: 28085895
    • DOI: 10.1371/journal.pone.0168622

    1 Insight on

    • Reduced Cardiac Hypertrophy

    • Low evidence
    • Rigorous Journal
• January 19

  • Antioxidant properties and global metabolite screening of the probiotic yeast Saccharomyces cerevisiae var. boulardii.

    • 2017-01-19
    • Journal of the Science of Food and Agriculture 97(9)
    • • S. Datta
      • D. Timson
      • U. Annapure

    • PubMed: 27868205
    • DOI: 10.1002/jsfa.8147

    2 Insights on

    • Improved Antioxidant Capacity
    • Improved Stress Tolerance

    • Low evidence
    • Rigorous Journal
• January 26

  • Promotility Action of the Probiotic Bifidobacterium lactis HN019 Extract Compared with Prucalopride in Isolated Rat Large Intestine

    • 2017-01-26
    • Clinical Trial · n = 20
    • Frontiers in Neuroscience 11
    • • J. Dalziel
      • R. Anderson
      • J. Peters
      • A. Lynch
      • N. Spencer
      • J. Dekker
      • N. Roy

    • PubMed: 28184185
    • DOI: 10.3389/fnins.2017.00020

    1 Insight on

    • Reduced Constipation

    • Low evidence
    • Animal Study
• January 27

  • Reduction of Aflatoxin B1 Toxicity by Lactobacillus plantarum C88: A Potential Probiotic Strain Isolated from Chinese Traditional Fermented Food “Tofu”

    • 2017-01-27
    • Clinical Trial
    • PLOS ONE 12(1)
    • • Li Huang
      • Cui-cui Duan
      • Yujuan Zhao
      • Lei Gao
      • Chunhua Niu
      • Jingbo Xu
      • Shengyu Li

    • PubMed: 28129335
    • DOI: 10.1371/journal.pone.0170109

    4 Insights on

    • Improved Antioxidant Capacity
    • Reduced Oxidative Stress
    • Improved Liver Histology
    • Increased Fecal Excretion of Aflatoxin B1

    • Low evidence
    • Highly Cited
    • Rigorous Journal
    • Animal Study
• Undated – 10 supplement studies

  • Dietary administration of Bacillus subtilis HAINUP40 enhances growth, digestive enzyme activities, innate immune responses and disease resistance of tilapia, Oreochromis niloticus

    • 2017-01
    • Clinical Trial
    • Fish & Shellfish Immunology 60
    • • Haitian Liu
      • Shifeng Wang
      • Yan Cai
      • Xiaohui Guo
      • Z. Cao
      • Yongzheng Zhang
      • Shubin Liu
      • W. Yuan
      • Weiwei Zhu
      • Yu Zheng
      • Zhenyu Xie
      • Weiliang Guo
      • Yong-can Zhou

    • PubMed: 27919757
    • DOI: 10.1016/j.fsi.2016.12.003

    6 Insights on

    • Improved Growth Performance
    • Enhanced Disease Resistance
    • Enhanced Digestive Enzyme Activity
    • Improved Antioxidant Capacity
    • Improved Innate Immune Response
    • Improved Digestive Enzyme Activity

    • Low evidence
    • Highly Cited
    • Animal Study

  • Effects of the dietary supplementation of mixed probiotic spores of Bacillus amyloliquefaciens 54A, and Bacillus pumilus 47B on growth, innate immunity and stress responses of striped catfish (Pangasianodon hypophthalmus)

    • 2017-01
    • Clinical Trial
    • Fish & Shellfish Immunology 60
    • • Ho Thi Truong Thy
      • N. N. Tri
      • Ong Moc Quy
      • R. Fotedar
      • K. Kannika
      • S. Unajak
      • N. Areechon

    • PubMed: 27836719
    • DOI: 10.1016/j.fsi.2016.11.016

    3 Insights on

    • Improved Immune Response
    • Improved Weight Gain
    • Reduced Mortality Rate under Stress

    • Low evidence
    • Highly Cited
    • Animal Study

  • A Mixture of 3 Bifidobacteria Decreases Abdominal Pain and Improves the Quality of Life in Children With Irritable Bowel Syndrome: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Crossover Trial

    • 2017-01
    • RCT · n = 76
    • Journal of Clinical Gastroenterology 51(1)
    • • E. Giannetti
      • M. Maglione
      • A. Alessandrella
      • C. Strisciuglio
      • D. De Giovanni
      • A. Campanozzi
      • E. Miele
      • A. Staiano

    • PubMed: 27306945
    • DOI: 10.1097/MCG.0000000000000528

    6 Insights on

    • Reduced Abdominal Pain Severity
    • Reduced Abdominal Pain Frequency
    • Improved Quality of Life
    • Complete Resolution of Abdominal Pain
    • Improved Abdominal Pain Frequency
    • Improved Abdominal Pain

    • High evidence
    • Highly Cited

  • Aronia berry polyphenol consumption reduces plasma total and low-density lipoprotein cholesterol in former smokers without lowering biomarkers of inflammation and oxidative stress: a randomized controlled trial.

    • 2017-01
    • RCT · n = 25
    • Nutrition research (New York, N.Y.) 37
    • • Liyang Xie
      • Terrence Vance
      • Bohkyung Kim
      • Sang Gil Lee
      • Christian Caceres
      • Ying Wang
      • Patrice A Hubert
      • Ji-Young Lee
      • Ock K Chun
      • Bradley W Bolling

    • PubMed: 28215316
    • DOI: 10.1016/j.nutres.2016.12.007

    5 Insights on

    • Reduced Low-Density Lipoprotein Level
    • Reduced Blood Pressure
    • Reduced Inflammation
    • Reduced Blood Cholesterol
    • Reduced Oxidative Stress

    • High evidence

  • Bifidobacterium breve reduces apoptotic epithelial cell shedding in an exopolysaccharide and MyD88-dependent manner

    • 2017-01
    • Clinical Trial
    • Open Biology 7(1)
    • • K. R. Hughes
      • L. C. Harnisch
      • L. C. Harnisch
      • Cristina Alcon-Giner
      • Suparna Mitra
      • C. J. Wright
      • C. J. Wright
      • Jennifer Ketskemety
      • D. Sinderen
      • Alastair J.M. Watson
      • Lindsay J. Hall

    • PubMed: 28123052
    • DOI: 10.1098/rsob.160155

    2 Insights on

    • Reduced Apoptotic Shedding of Epithelial Cells
    • Protected Epithelial Cells Under Inflammatory Conditions

    • Low evidence
    • Animal Study

  • Integrated transcriptomic and proteomic analysis of the bile stress response in probiotic Lactobacillus salivarius LI01.

    • 2017-01
    • Journal of Proteomics 150
    • • L. Lv
      • Ren Yan
      • Hai-Yan Shi
      • D. Shi
      • D. Fang
      • Huiyong Jiang
      • Wen-rui Wu
      • F. Guo
      • Xia-wei Jiang
      • Silan Gu
      • Yun-bo Chen
      • Jian Yao
      • Lanjuan Li

    • PubMed: 27585996
    • DOI: 10.1016/j.jprot.2016.08.021

    3 Insights on

    • Improved Liver Function
    • Improved Tolerance to Bile Salts
    • Enhanced Liver Protection

    • Low evidence

  • Oral magnesium supplementation improves endothelial function and attenuates subclinical atherosclerosis in thiazide-treated hypertensive women.

    • 2017-01
    • RCT
    • Journal of hypertension 35(1)
    • • Ana Rosa Cunha
      • Jenifer D'El-Rei
      • Fernanda Medeiros
      • Bianca Umbelino
      • Wille Oigman
      • Rhian M Touyz
      • Mario F Neves

    • PubMed: 27759579
    • DOI: 10.1097/hjh.0000000000001129

    1 Insight on

    • Improved Vascular Endothelial Function

    • High evidence

  • Lactobacillus reuteri DSM 17938 in the prevention of antibiotic-associated diarrhoea in children: protocol of a randomised controlled trial

    • 2017-01
    • RCT · n = 250
    • BMJ Open 7(1)
    • • M. Kołodziej
      • H. Szajewska

    • PubMed: 28057659
    • DOI: 10.1136/bmjopen-2016-013928

    1 Insight on

    • Reduced Antibiotic-Associated Diarrhea

    • High evidence
    • Rigorous Journal

  • Lactobacillus helveticus Lafti L10 Supplementation Modulates Mucosal and Humoral Immunity in Elite Athletes: A Randomized, Double-Blind, Placebo-Controlled Trial

    • 2017-01
    • RCT · n = 30
    • Journal of Strength and Conditioning Research 31(1)
    • • D. Michaličková
      • Marija Kostic-Vucicevic
      • M. Vukasinović-Vesić
      • Tamara Stojmenovic
      • N. Dikić
      • M. Andjelkovic
      • B. Djordjevic
      • Bojana P Tanaskovic
      • R. Minić

    • PubMed: 27100317
    • DOI: 10.1519/JSC.0000000000001456

    4 Insights on

    • Elevated Total IgM Levels
    • Reduced Anti-Enterococcus faecalis IgG Levels
    • Decreased Total IgA Levels
    • Reduced Serum Anti-Lactic Acid Bacteria IgA Levels

    • High evidence

  • L-Methylfolate For Bipolar I depressive episodes: An open trial proof-of-concept registry.

    • 2017-01
    • Clinical Trial · n = 10
    • Journal of affective disorders 207
    • • Andrew A Nierenberg
      • Rebecca Montana
      • Gustavo Kinrys
      • Thilo Deckersbach
      • Steven Dufour
      • Ji Hyun Baek

    • PubMed: 27794238
    • DOI: 10.1016/j.jad.2016.09.053

    2 Insights on

    • Reduced Depression Symptoms
    • Reduced Manic Symptoms

    • Moderate evidence