October 2017 Supplement Research Papers

• October 12

  • Probiotics for the Prevention of Antibiotic-Associated Diarrhea in Outpatients—A Systematic Review and Meta-Analysis

    • 2017-10-12
    • Meta-Analysis
    • Antibiotics 6(4)
    • • Sara Blaabjerg
      • D. Artzi
      • R. Aabenhus

    • PubMed: 29023420
    • DOI: 10.3390/antibiotics6040021

    2 Insights on

    • Reduced Antibiotic-Associated Diarrhea
    • Increased Safety of Probiotic Use

    • High evidence
    • Highly Cited

  • Flavanol-Rich Cocoa Powder Interacts with Lactobacillus rhamnossus LGG to Alter the Antibody Response to Infection with the Parasitic Nematode Ascaris suum

    • 2017-10-12
    • RCT
    • Nutrients 9(10)
    • • Saebyeol Jang
      • Sukla Lakshman
      • E. Beshah
      • Yue Xie
      • Aleksey Molokin
      • B. Vinyard
      • J. Urban
      • C. Davis
      • G. Solano-Aguilar

    • PubMed: 29023393
    • DOI: 10.3390/nu9101113

    3 Insights on

    • Increased Fecal Lactobacilli
    • Reduced Anti-Ascaris suum IgG2 Antibody Levels
    • Delayed Intestinal Expulsion of Parasitic Larvae

    • High evidence
• October 13

  • Lactobacillus plantarum IS-10506 supplementation reduced SCORAD in children with atopic dermatitis.

    • 2017-10-13
    • RCT · n = 22
    • Beneficial Microbes 8(5)
    • • C. Prakoeswa
      • N. Herwanto
      • R. Prameswari
      • L. Astari
      • S. Sawitri
      • A. Hidayati
      • D. Indramaya
      • E. R. Kusumowidagdo
      • I. Surono

    • PubMed: 29022387
    • DOI: 10.3920/BM2017.0011

    7 Insights on

    • Reduced Interleukin-4 Levels
    • Reduced Interferon-Gamma Levels
    • Improved Atopic Dermatitis Severity
    • Reduced SCORAD Index
    • Reduced IL-4 Levels
    • Reduced Levels of Interleukin-17
    • Increased Foxp3+ to IL-10 Ratio

    • High evidence
• October 18

  • Therapeutic potential of Bifidobacterium breve strain A1 for preventing cognitive impairment in Alzheimer's disease.

    • 2017-10-18
    • Scientific reports 7(1)
    • • Yodai Kobayashi
      • Hirosuke Sugahara
      • Kousuke Shimada
      • Eri Mitsuyama
      • Tetsuya Kuhara
      • Akihito Yasuoka
      • Takashi Kondo
      • Keiko Abe
      • Jin-Zhong Xiao

    • PubMed: 29044140
    • DOI: 10.1038/s41598-017-13368-2

    2 Insights on

    • Improved Cognitive Function
    • Reduced Neuroinflammation

    • Low evidence
    • Highly Cited
    • Rigorous Journal
    • Animal Study
• October 19

  • Clostridium butyricum CGMCC0313.1 Protects against Autoimmune Diabetes by Modulating Intestinal Immune Homeostasis and Inducing Pancreatic Regulatory T Cells

    • 2017-10-19
    • RCT
    • Frontiers in Immunology 8
    • • Lingling Jia
      • Kai Shan
      • Li-Long Pan
      • Ninghan Feng
      • Zhuwu Lv
      • Yajun Sun
      • Jiahong Li
      • Chengfei Wu
      • Hao Zhang
      • Wei Chen
      • J. Diana
      • Jia Sun
      • Yong Q. Chen

    • PubMed: 29097999
    • DOI: 10.3389/fimmu.2017.01345

    6 Insights on

    • Improved Gut Microbiome Composition
    • Increased Regulatory T Cell Count
    • Reduced Inflammation
    • Improved Energy Metabolism
    • Delayed Onset of Type 1 Diabetes
    • Rebalanced Th1/Th2/Th17 Cell Ratios

    • Low evidence
    • Animal Study
• October 31

  • Antibacterial Effects against Various Foodborne Pathogens and Sensory Properties of Yogurt Supplemented with Panax ginseng Marc Extract.

    • 2017-10-31
    • Korean journal for food science of animal resources 37(5)
    • • Su Jin Eom
      • Ji Eun Hwang
      • Kee-Tae Kim
      • Hyun-Dong Paik

    • PubMed: 29147103
    • DOI: 10.5851/kosfa.2017.37.5.787

    1 Insight on

    • Reduced Pathogen Growth

    • Low evidence
• Undated – 8 supplement studies

  • Effect of Lactobacillus rhamnosus HN001 in Pregnancy on Postpartum Symptoms of Depression and Anxiety: A Randomised Double-blind Placebo-controlled Trial

    • 2017-10
    • RCT · n = 423
    • EBioMedicine 24
    • • R. Slykerman
      • Fiona Hood
      • K. Wickens
      • John F. Thompson
      • C. Barthow
      • R. Murphy
      • Janice Kang
      • Judy Rowden
      • P. Stone
      • Julian Crane
      • T. Stanley
      • P. Abels
      • G. Purdie
      • Robyn M. Maude
      • E. Mitchell

    • PubMed: 28943228
    • DOI: 10.1016/j.ebiom.2017.09.013

    7 Insights on

    • Reduced Depression Symptoms
    • Reduced Anxiety Symptoms
    • Reduced Clinically Relevant Anxiety
    • Reduced Anxiety
    • Reduced Clinically Relevant Postpartum Anxiety
    • Reduced Anxiety Scores
    • Reduced Depression Score

    • High evidence
    • Large Human Trial
    • Highly Cited
    • Rigorous Journal

  • Specific Signatures of the Gut Microbiota and Increased Levels of Butyrate in Children Treated with Fermented Cow's Milk Containing Heat-Killed Lactobacillus paracasei CBA L74

    • 2017-10
    • RCT · n = 20
    • Applied and Environmental Microbiology 83(19)
    • • R. Berni Canani
      • F. De Filippis
      • R. Nocerino
      • M. Laiola
      • L. Paparo
      • A. Calignano
      • C. De Caro
      • L. Coretti
      • L. Chiariotti
      • J. Gilbert
      • D. Ercolini

    • PubMed: 28733284
    • DOI: 10.1128/AEM.01206-17

    4 Insights on

    • Improved Gut Microbiota Composition
    • Increased Butyrate Levels
    • Increased Butyrate Production
    • Improved Immunity Biomarkers

    • High evidence
    • Highly Cited

  • Dietary Bacillus subtilis-based direct-fed microbials alleviate LPS-induced intestinal immunological stress and improve intestinal barrier gene expression in commercial broiler chickens.

    • 2017-10
    • RCT
    • Research in Veterinary Science 114
    • • U. Gadde
      • Sungtaek Oh
      • Youngsub Lee
      • E. Davis
      • N. Zimmerman
      • T. Rehberger
      • H. Lillehoj

    • PubMed: 28505587
    • DOI: 10.1016/j.rvsc.2017.05.004

    4 Insights on

    • Increased Body Weight
    • Increased CD4 Counts
    • Reduced Serum α-1-Acid Glycoprotein Levels
    • Reduced CD8+ Lymphocytes Count

    • Low evidence
    • Highly Cited
    • Animal Study

  • Leuconostoc mesenteroides-derived anticancer pharmaceuticals hinder inflammation and cell survival in colon cancer cells by modulating NF-κB/AKT/PTEN/MAPK pathways.

    • 2017-10
    • Biomedicine & Pharmacotherapy 94
    • • S. Zununi Vahed
      • A. Barzegari
      • Yalda Rahbar Saadat
      • Ali Goreyshi
      • Y. Omidi

    • PubMed: 28821160
    • DOI: 10.1016/j.biopha.2017.08.033

    1 Insight on

    • Reduced Inflammation

    • Low evidence
    • Rigorous Journal

  • Digestion of Human Milk Oligosaccharides by Bifidobacterium breve in the Premature Infant

    • 2017-10
    • Clinical Trial · n = 29
    • Journal of Pediatric Gastroenterology and Nutrition 65(4)
    • • M. Underwood
      • Jasmine C C Davis
      • K. Kalanetra
      • S. Gehlot
      • S. Patole
      • D. Tancredi
      • D. Mills
      • C. Lebrilla
      • K. Simmer

    • PubMed: 28945208
    • DOI: 10.1097/MPG.0000000000001590

    6 Insights on

    • Increased Fecal Bifidobacteria Levels
    • Improved Gut Microbiome Composition
    • Reduced Fungal Enteric Colonization
    • Improved Intestinal Microbial Composition
    • Reduced Enterobacteriaceae Levels in Feces
    • Selective Consumption of Human Milk Oligosaccharides (HMOs)

    • Moderate evidence

  • Effect of fermented milk containing Lactobacillus rhamnosus SD11 on oral microbiota of healthy volunteers: A randomized clinical trial.

    • 2017-10
    • RCT · n = 43
    • Journal of Dairy Science 100(10)
    • • P. Rungsri
      • N. Akkarachaneeyakorn
      • Mutita Wongsuwanlert
      • S. Piwat
      • P. Nantarakchaikul
      • R. Teanpaisan

    • PubMed: 28803012
    • DOI: 10.3168/jds.2017-12961

    15 Insights on

    • Reduced Salivary Levels of Mutans Streptococci
    • Increased Salivary Lactobacilli Levels
    • Colonization of Lactobacillus rhamnosus SD11 in Oral Cavity
    • Increased Lactobacilli Levels
    • Absence of Adverse Effects
    • No Reported Adverse Effects
    • Increased Lactobacillus Levels
    • Reduced Bacterial Load
    • Improved Lactobacillus Counts
    • Reduced Streptococcus Mutans Levels
    • No Observed Side Effects
    • No Adverse Side Effects
    • Reduced Bacterial Load in Saliva
    • Reduced Total Bacterial Levels
    • Colonization of Oral Cavity

    • High evidence
    • Rigorous Journal

  • Cytokine production in vitro and in rat model of colitis in response to Lactobacillus plantarum LS/07.

    • 2017-10
    • Clinical Trial
    • Biomedicine & Pharmacotherapy 94
    • • Jana Štofilová
      • T. Langerholc
      • C. Botta
      • P. Treven
      • L. Gradišnik
      • Rastislav Salaj
      • A. Šoltésová
      • I. Bertková
      • Z. Hertelyová
      • A. Bomba

    • PubMed: 28830068
    • DOI: 10.1016/j.biopha.2017.07.138

    3 Insights on

    • Reduced Inflammation Levels
    • Increased IL-10 Production
    • Increased IL-10 in Mucosal Tissue

    • Low evidence
    • Rigorous Journal
    • Animal Study

  • Impact of lyophilized Lactobacillus salivarius DSPV 001P administration on growth performance, microbial translocation, and gastrointestinal microbiota of broilers reared under low ambient temperature.

    • 2017-10
    • RCT
    • Research in Veterinary Science 114
    • • J. Blajman
      • C. Olivero
      • M. L. Fusari
      • J. Zimmermann
      • E. Rossler
      • A. Berisvil
      • A. R. Scharpen
      • D. Astesana
      • L. Soto
      • Marcelo Signorini
      • M. V. Zbrun
      • L. Frizzo

    • PubMed: 28743079
    • DOI: 10.1016/j.rvsc.2017.07.011

    6 Insights on

    • Reduced Colitis-Related Mortality
    • Improved Body Weight
    • Improved Growth Performance
    • Reduced Mortality Risk
    • Unchanged Intestinal Bacterial Concentrations
    • Maintained Intestinal Microbiota Balance

    • High evidence