May 2009 Supplement Research Papers

• May 12

  • Suppressive effects of bifidobacterium breve strain M-16V on T-helper type 2 immune responses in a murine model.

    • 2009-05-12
    • Clinical Trial
    • Biological and Pharmaceutical Bulletin 32(4)
    • • Y. Inoue
      • N. Iwabuchi
      • J. Xiao
      • T. Yaeshima
      • K. Iwatsuki

    • PubMed: 19336921
    • DOI: 10.1248/BPB.32.760

    4 Insights on

    • Reduced Serum OVA-specific IgE Levels
    • Reduced Serum IgE Levels
    • Reduced Serum OVA-specific IgG1 Levels
    • Modulated Systemic Th1/Th2 Balance

    • Low evidence
    • Animal Study
• May 15

  • Effects of Lactobacillus plantarum MA2 isolated from Tibet kefir on lipid metabolism and intestinal microflora of rats fed on high-cholesterol diet

    • 2009-05-15
    • Clinical Trial
    • Applied Microbiology and Biotechnology 84(2)
    • • Yanping Wang
      • N. Xu
      • A. Xi
      • Zaheer Ahmed
      • Bin Zhang
      • Xiaojia Bai

    • PubMed: 19444443
    • DOI: 10.1007/s00253-009-2012-x

    19 Insights on

    • Improved Gut Microbiota
    • Reduced Total Cholesterol Levels
    • Reduced Low-Density Lipoprotein Level
    • Reduced Triglyceride Levels
    • Reduced LDL Cholesterol
    • Reduced Serum Total Cholesterol Levels
    • Stable High-Density Lipoprotein Cholesterol Level
    • Reduced Liver Triglyceride Content
    • Increased Fecal Cholesterol Levels
    • No Change in E. coli Count
    • Reduced Liver Triglycerides
    • Reduced Triglycerides
    • Reduced Liver Cholesterol
    • Increased Bifidobacterium Levels in Feces
    • Increased Fecal Lactic Acid Bacteria Counts
    • Reduced Escherichia coli Population
    • No Change in HDL Cholesterol
    • Increased Fecal Triglyceride Levels
    • Stable Escherichia coli Population in Fecal Matter

    • Low evidence
    • Highly Cited
    • Animal Study

  • Vaginal colonization by probiotic Lactobacillus crispatus CTV-05 is decreased by sexual activity and endogenous Lactobacilli.

    • 2009-05-15
    • RCT · n = 90
    • The Journal of Infectious Diseases 199(10)
    • • M. Antonio
      • L. Meyn
      • P. Murray
      • B. Busse
      • S. Hillier

    • PubMed: 19331578
    • DOI: 10.1086/598686

    2 Insights on

    • Reduced Vaginal Colonization by Probiotic Lactobacillus
    • Increased Vaginal Colonization by Lactobacillus crispatus CTV-05

    • High evidence
    • Highly Cited
    • Rigorous Journal
• May 18

  • Probiotic effects of orally administered Lactobacillus salivarius WB21-containing tablets on periodontopathic bacteria: a double-blinded, placebo-controlled, randomized clinical trial.

    • 2009-05-18
    • RCT · n = 66
    • Journal of Clinical Periodontology 36(6)
    • • G. Mayanagi
      • Moto Kimura
      • S. Nakaya
      • H. Hirata
      • M. Sakamoto
      • Y. Benno
      • H. Shimauchi

    • PubMed: 19453574
    • DOI: 10.1111/j.1600-051X.2009.01392.x

    5 Insights on

    • Reduced Periodontopathic Bacteria
    • Reduced Tannerella Forsythia Levels
    • Improved Periodontal Health
    • Reduced Tannerella forsythia in Subgingival Plaque
    • Reduced Pathogenic Bacteria

    • High evidence
    • Highly Cited
• Undated – 3 supplement studies

  • Dietary administration of the probiotic, Lactobacillus plantarum, enhanced the growth, innate immune responses, and disease resistance of the grouper Epinephelus coioides.

    • 2009-05
    • Fish & Shellfish Immunology 26(5)
    • • V. M. Son
      • Chin-Chyuan Chang
      • Mingjuan Wu
      • Y. Guu
      • C. Chiu
      • W. Cheng

    • PubMed: 19264134
    • DOI: 10.1016/j.fsi.2009.02.018

    6 Insights on

    • Increased PMN Cell Phagocytic Capacity
    • Increased Serum Lysozyme Activity
    • Increased Body Weight
    • Increased Glutathione Peroxidase Activity
    • Improved Survival Rate After Bacterial Challenge
    • Enhanced Alternative Complement Activity

    • Low evidence
    • Highly Cited

  • Effect of Lactobacillus rhamnosus GR-1 supernatant and fetal sex on lipopolysaccharide-induced cytokine and prostaglandin-regulating enzymes in human placental trophoblast cells: implications for treatment of bacterial vaginosis and prevention of preterm labor.

    • 2009-05
    • American Journal of Obstetrics and Gynecology 200(5)
    • • M. Yeganegi
      • C. Watson
      • A. Martins
      • S. O. Kim
      • G. Reid
      • J. Challis
      • A. Bocking

    • PubMed: 19285652
    • DOI: 10.1016/j.ajog.2008.12.032

    4 Insights on

    • Increased Interleukin-10 Levels
    • Reduced TNF-α Levels
    • Increased PGDH Expression in Female Placentae
    • Partially Reduced PTGS2 Levels in Male Placentas

    • Low evidence
    • Highly Cited

  • Synbiotic promotion of epithelial proliferation by orally ingested encapsulated Bifidobacterium breve and raffinose in the small intestine of rats.

    • 2009-05
    • RCT
    • Molecular Nutrition & Food Research 53(S1)
    • • S. Ishizuka
      • Ami Iwama
      • A. Dinoto
      • A. Suksomcheep
      • K. Maeta
      • T. Kasai
      • H. Hara
      • A. Yokota

    • PubMed: 18837471
    • DOI: 10.1002/mnfr.200800041

    1 Insight on

    • Increased Epithelial Proliferation in the Small Intestine

    • High evidence