July 2014 Supplement Research Papers

• July 1

  • Efficacy and Safety of Saccharomyces boulardii for Acute Diarrhea

    • 2014-07-01
    • Systematic Review
    • Pediatrics 134(1)
    • • S. Feizizadeh
      • A. Salehi-abargouei
      • Vajihe Akbari

    • PubMed: 24958586
    • DOI: 10.1542/peds.2013-3950

    5 Insights on

    • Reduced Duration of Diarrhea
    • Reduced Stool Frequency
    • Reduced Diarrhea Rate
    • Reduced Risk of Diarrhea on Day 3
    • Reduced Risk of Diarrhea on Day 4

    • High evidence
    • Highly Cited

  • Phytotherapy of benign prostatic hyperplasia. A minireview.

    • 2014-07-01
    • Review
    • Phytotherapy research : PTR 28(7)
    • • Ester Pagano
      • Massimiliano Laudato
      • Michele Griffo
      • Raffaele Capasso

    • PubMed: 25165780
    • DOI: 10.1002/ptr.5084

    1 Insight on

    • Improved Lower Urinary Tract Symptoms

    • Low evidence
• July 4

  • Antiviral activity of Bifidobacterium adolescentis SPM1605 against Coxsackievirus B3

    • 2014-07-04
    • Biotechnology & Biotechnological Equipment 28(4)
    • • Min Ji Kim
      • Do Kyung Lee
      • J. E. Park
      • I. Park
      • Jae-gu Seo
      • N. Ha

    • PubMed: 26019554
    • DOI: 10.1080/13102818.2014.945237

    2 Insights on

    • Reduced Coxsackievirus B3 Activity
    • Reduced Coxsackievirus B3 Viral Load

    • Low evidence
• July 7

  • Bifidobacterium longum subsp. infantis in experimental necrotizing enterocolitis: alterations in inflammation, innate immune response, and the microbiota

    • 2014-07-07
    • Pediatric Research 76(4)
    • • M. Underwood
      • J. Arriola
      • Colin W. Gerber
      • Ashwini Kaveti
      • K. Kalanetra
      • Anchasa Kananurak
      • C. Bevins
      • D. Mills
      • B. Dvořák

    • PubMed: 25000347
    • DOI: 10.1038/pr.2014.102

    4 Insights on

    • Reduced Occurrence of Necrotizing Enterocolitis
    • Reduced Risk of Necrotizing Enterocolitis
    • Reduced NEC Incidence
    • Altered Innate Immune Response

    • Moderate evidence
    • Highly Cited
    • Rigorous Journal
• July 15

  • Converging effects of a Bifidobacterium and Lactobacillus probiotic strain on mouse intestinal physiology.

    • 2014-07-15
    • Clinical Trial
    • American Journal of Physiology-Gastrointestinal and Liver Physiology 307(2)
    • • K. W. Lomasney
      • J. Cryan
      • N. Hyland

    • PubMed: 24852567
    • DOI: 10.1152/ajpgi.00401.2013

    4 Insights on

    • Reduced Small Intestinal Transit Time
    • Increased Colonic Transepithelial Resistance
    • Reduced Neurally Evoked Ion Secretion in the Colon
    • Reduced Sensitivity to Tetrodotoxin (TTx) Inhibition in Short-circuit Current Response

    • Low evidence
    • Animal Study
• July 16

  • Probiotic Properties of Lactobacillus crispatus 2,029: Homeostatic Interaction with Cervicovaginal Epithelial Cells and Antagonistic Activity to Genitourinary Pathogens

    • 2014-07-16
    • Probiotics and Antimicrobial Proteins 6(3-4)
    • • V. Abramov
      • V. Khlebnikov
      • I. Kosarev
      • Guldana Bairamova
      • R. Vasilenko
      • N. Suzina
      • A. Machulin
      • V. Sakulin
      • N. Kulikova
      • Nadezhda F. Vasilenko
      • A. V. Karlyshev
      • V. Uversky
      • M. Chikindas
      • V. Melnikov

    • PubMed: 25028263
    • DOI: 10.1007/s12602-014-9164-4

    15 Insights on

    • Reduced Inflammatory Response
    • Regulated Immune Response
    • Enhanced Resistance to Infections
    • Reduced Inflammation Levels
    • Reduced Inflammation in the Female Reproductive Tract
    • Non-toxicity to Cervicovaginal Epithelial Cells
    • Reduced Urogenital Pathogen Activity
    • Reduced Pathogen Colonization
    • Non-Toxic Colonization
    • Maintained Homeostasis
    • Maintained Female Reproductive Tract Homeostasis
    • Improved Colonization Resistance
    • Improved Colonization Resistance to Pathogens
    • Absence of Exogenous Toxicity
    • Adhesion to Cervicovaginal Epithelial Cells

    • Low evidence
• July 19

  • Chronic bacterial prostatitis: efficacy of short-lasting antibiotic therapy with prulifloxacin (Unidrox®) in association with saw palmetto extract, lactobacillus sporogens and arbutin (Lactorepens®).

    • 2014-07-19
    • RCT · n = 210
    • BMC urology 14
    • • Gian Maria Busetto
      • Riccardo Giovannone
      • Matteo Ferro
      • Stefano Tricarico
      • Francesco Del Giudice
      • Deliu Victor Matei
      • Ottavio De Cobelli
      • Vincenzo Gentile
      • Ettore De Berardinis

    • PubMed: 25038794
    • DOI: 10.1186/1471-2490-14-53

    6 Insights on

    • Improved Symptoms
    • Reduced Infection Recurrence
    • Reduced Total Prostate-Specific Antigen Level
    • Improved Chronic Prostatitis Symptom Index Score
    • Reduced Disease Recurrence
    • Improved Symptom Severity

    • High evidence
    • Large Human Trial
• July 21

  • Probiotic-enriched foods and dietary supplement containing SYNBIO positively affects bowel habits in healthy adults: an assessment using standard statistical analysis and Support Vector Machines

    • 2014-07-21
    • RCT · n = 200
    • International Journal of Food Sciences and Nutrition 65(8)
    • • S. Silvi
      • M. Verdenelli
      • C. Cecchini
      • M. Coman
      • M. Bernabei
      • Jessica Rosati
      • R. De Leone
      • C. Orpianesi
      • A. Cresci

    • PubMed: 25045832
    • DOI: 10.3109/09637486.2014.940284

    1 Insight on

    • Improved Intestinal Function

    • High evidence

  • Effects of Bifidobacterium bifidum G9-1 on Nasal Symptoms in a Guinea Pig Model of Experimental Allergic Rhinitis

    • 2014-07-21
    • Clinical Trial
    • Bioscience and Microflora 30(1)
    • • Satoru Tsunemine
      • Y. Isa
      • M. Shimakawa
      • H. Ohno
      • H. Yamamura

    • PubMed: 25045310
    • DOI: 10.12938/bifidus.30.1

    1 Insight on

    • Reduced Nasal Symptoms

    • Low evidence
    • Animal Study
• July 23

  • Effects of probiotic supplementation over 5 months on routine haematology and clinical chemistry measures in healthy active adults.

    • 2014-07-23
    • RCT
    • European journal of clinical nutrition 68(11)
    • • A J Cox
      • N P West
      • P L Horn
      • M J Lehtinen
      • G Koerbin
      • D B Pyne
      • S J Lahtinen
      • P A Fricker
      • A W Cripps

    • PubMed: 25052229
    • DOI: 10.1038/ejcn.2014.137

    4 Insights on

    • Reduced Plasma Urea Level
    • Reduced Calcium Level
    • Altered Hematology Profile
    • Changed Clinical Chemistry Measure

    • High evidence
    • Rigorous Journal
• July 24

  • Effect of yogurt containing polydextrose, Lactobacillus acidophilus NCFM and Bifidobacterium lactis HN019: a randomized, double-blind, controlled study in chronic constipation.

    • 2014-07-24
    • RCT
    • Nutrition journal 13(1)
    • • Daniéla Oliveira Magro
      • Lais Mariana R de Oliveira
      • Isabela Bernasconi
      • Marilia de Souza Ruela
      • Laura Credidio
      • Irene K Barcelos
      • Raquel F Leal
      • Maria de Lourdes Stesuko Ayrizono
      • João José Fagundes
      • Leandro de B Teixeira
      • Arthur C Ouwehand
      • Claudio S R Coy

    • PubMed: 25056655
    • DOI: 10.1186/1475-2891-13-75

    2 Insights on

    • Reduced Constipation Severity
    • Reduced Transit Time

    • High evidence
• July 25

  • Probiotic Bifidobacterium animalis subsp. lactis Bi-07 alleviates bacterial translocation and ameliorates microinflammation in experimental uraemia.

    • 2014-07-25
    • Nephrology (Carlton, Vic.) 19(8)
    • • Meng Wei
      • Zhigang Wang
      • Hua Liu
      • Hongli Jiang
      • Meng Wang
      • Shanshan Liang
      • Kehui Shi
      • Jie Feng

    • PubMed: 24787732
    • DOI: 10.1111/nep.12272

    3 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Bacterial Translocation
    • Reduced Inflammation

    • Low evidence
    • Animal Study
• July 28

  • Functional characterization of probiotic surface layer protein-carrying Lactobacillus amylovorus strains.

    • 2014-07-28
    • BMC microbiology 14(1)
    • • Ulla Hynönen
      • Ravi Kant
      • Tanja Lähteinen
      • Taija E Pietilä
      • Jasna Beganović
      • Hauke Smidt
      • Ksenija Uroić
      • Silja Avall-Jääskeläinen
      • Airi Palva

    • PubMed: 25070625
    • DOI: 10.1186/1471-2180-14-199

    3 Insights on

    • Increased Inhibition of Pathogenic Bacteria
    • Enhanced Intestinal Epithelial Cell Adhesion
    • Improved Immune System Modulation

    • Low evidence
    • Animal Study
• July 29

  • Technological Aptitude and Applications of Leuconostoc mesenteroides Bioactive Strains Isolated from Algerian Raw Camel Milk

    • 2014-07-29
    • BioMed Research International 2013
    • • Z. Benmechernene
      • H. Chentouf
      • B. Yahia
      • G. Fatima
      • M. Quintela-Baluja
      • P. Calo-Mata
      • J. Barros-Velázquez

    • PubMed: 24392451
    • DOI: 10.1155/2013/418132

    1 Insight on

    • Reduced Pathogen Activity

    • Low evidence
• Undated – 4 supplement studies

  • Saccharomyces boulardii Administration Changes Gut Microbiota and Reduces Hepatic Steatosis, Low-Grade Inflammation, and Fat Mass in Obese and Type 2 Diabetic db/db Mice

    • 2014-07
    • Clinical Trial
    • mBio 5(3)
    • • A. Everard
      • S. Matamoros
      • L. Geurts
      • N. Delzenne
      • Patrice D Cani

    • PubMed: 24917595
    • DOI: 10.1128/mBio.01011-14

    4 Insights on

    • Reduced Body Weight
    • Reduced Body Fat Mass
    • Reduced Hepatic Steatosis
    • Reduced Inflammatory Tone

    • Low evidence
    • Highly Cited
    • Animal Study

  • Lactobacillus plantarum CLP-0611 ameliorates colitis in mice by polarizing M1 to M2-like macrophages.

    • 2014-07
    • Clinical Trial
    • International Immunopharmacology 21(1)
    • • Se-Eun Jang
      • M. Han
      • Se-Young Kim
      • Dong-Hyun Kim

    • PubMed: 24815859
    • DOI: 10.1016/j.intimp.2014.04.021

    3 Insights on

    • Reduced Inflammation Levels
    • Improved Colitis Symptoms
    • Enhanced Anti-Inflammatory Cytokine Production

    • Low evidence
    • Highly Cited
    • Animal Study

  • Probiotic Lactobacillus rhamnosus GR-1 supernatant prevents lipopolysaccharide-induced preterm birth and reduces inflammation in pregnant CD-1 mice.

    • 2014-07
    • Clinical Trial
    • American Journal of Obstetrics and Gynecology 211(1)
    • • Siwen Yang
      • Wei Li
      • J. Challis
      • G. Reid
      • S. O. Kim
      • A. Bocking

    • PubMed: 24486224
    • DOI: 10.1016/j.ajog.2014.01.029

    2 Insights on

    • Reduced Preterm Births
    • Reduced Inflammation

    • Low evidence
    • Animal Study

  • Modulation of the inflammation–coagulation interaction during pneumococcal pneumonia by immunobiotic Lactobacillus rhamnosus CRL1505: Role of Toll‐like receptor 2

    • 2014-07
    • Clinical Trial
    • Microbiology and Immunology 58(7)
    • • H. Zelaya
      • J. Villena
      • Andres Gramajo Lopez
      • S. Alvarez
      • Graciela Agüero

    • PubMed: 24888715
    • DOI: 10.1111/1348-0421.12163

    2 Insights on

    • Reduced Lung Damage
    • Improved Cytokine Production

    • Low evidence
    • Animal Study