March 2017 Supplement Research Papers

• March 3

  • Anti-nociceptive effects of Paecilomyces hepiali via multiple pathways in mouse models.

    • 2017-03-03
    • Clinical Trial
    • Genetics and Molecular Research 15(3)
    • • C. Wang
      • Juan Wang
      • D. Jia
      • Leilei Li
      • B. Jia
      • S. Fan
      • Junfeng Song
      • X. Hu
      • Yan Wang
      • Di Wang

    • PubMed: 27706666
    • DOI: 10.4238/gmr.15038996

    3 Insights on

    • Normalized Neurotransmitter Levels
    • Reduced Neurogenic Pain
    • Reduced Thermal Pain Sensation

    • Low evidence
    • Animal Study
• March 6

  • Lactobacillus rhamnosus GG supernatant enhance neonatal resistance to systemic Escherichia coli K1 infection by accelerating development of intestinal defense

    • 2017-03-06
    • Clinical Trial
    • Scientific Reports 7(1)
    • • Xiaolong He
      • Qing Zeng
      • Santhosh Puthiyakunnon
      • Zhijie Zeng
      • Weijun Yang
      • Jiawen Qiu
      • Lei Du
      • S. Boddu
      • Tongwei Wu
      • Danxian Cai
      • Sheng-He Huang
      • Hong-yong Cao

    • PubMed: 28262688
    • DOI: 10.1038/srep43305

    3 Insights on

    • Improved Intestinal Barrier Integrity
    • Reduced Susceptibility to Systemic Escherichia coli K1 Infection
    • Enhanced Intestinal Defense Maturation

    • Low evidence
    • Animal Study
• March 7

  • Lactobacillus plantarum and Its Probiotic and Food Potentialities

    • 2017-03-07
    • Review
    • Probiotics and Antimicrobial Proteins 9(2)
    • • H. Seddik
      • F. Bendali
      • F. Gancel
      • I. Fliss
      • G. Spano
      • D. Drider

    • PubMed: 28271469
    • DOI: 10.1007/s12602-017-9264-z

    3 Insights on

    • Improved Gut Health
    • Enhanced Antimicrobial Resistance
    • Improved Probiotic Safety

    • Moderate evidence
    • Highly Cited

  • Lactobacillus paracasei modulates the immune system of Galleria mellonella and protects against Candida albicans infection

    • 2017-03-07
    • Clinical Trial
    • PLOS ONE 12(3)
    • • R. D. Rossoni
      • B. Fuchs
      • P. P. de Barros
      • Marisol dos Santos Velloso
      • A. O. Jorge
      • J. C. Junqueira
      • E. Mylonakis

    • PubMed: 28267809
    • DOI: 10.1371/journal.pone.0173332

    9 Insights on

    • Improved Cell Survival Rates
    • Increased Expression of Antimicrobial Peptide Genes
    • Improved Larvae Survival Rate
    • Increased Hemocyte Count
    • Reduced Fungal Cell Count
    • Improved Survival Rate Following Infection
    • Increased Antifungal Peptide Production
    • Reduced Fungal Load
    • Increased Antifungal Peptides

    • Low evidence
    • Highly Cited
    • Rigorous Journal
    • Animal Study

  • Lactobacillus reuteri Surface Mucus Adhesins Upregulate Inflammatory Responses Through Interactions With Innate C-Type Lectin Receptors

    • 2017-03-07
    • Frontiers in Microbiology 8
    • • Krisztián Bene
      • D. Kavanaugh
      • C. Leclaire
      • A. P. Gunning
      • D. Mackenzie
      • Alexandra Wittmann
      • Ian D Young
      • N. Kawasaki
      • E. Rajnavolgyi
      • N. Juge

    • PubMed: 28326063
    • DOI: 10.3389/fmicb.2017.00321

    2 Insights on

    • Increased Pro-inflammatory Cytokine Release
    • Th1 Polarized Immune Response Through Activation of moDCs

    • Low evidence

  • Bifidobacterium breve with α-linolenic acid alters the composition, distribution and transcription factor activity associated with metabolism and absorption of fat

    • 2017-03-07
    • RCT
    • Scientific Reports 7(1)
    • • E. Patterson
      • E. Patterson
      • R. Wall
      • R. Wall
      • Sara Lisai
      • R. Ross
      • T. Dinan
      • J. Cryan
      • G. Fitzgerald
      • S. Banni
      • E. Quigley
      • F. Shanahan
      • C. Stanton
      • C. Stanton

    • PubMed: 28265110
    • DOI: 10.1038/srep43300

    7 Insights on

    • Reduced Liver Triglyceride Content
    • Reduced Liver Triglycerides
    • Increased n-3 Polyunsaturated Fatty Acid Levels
    • Enhanced Hepatic Peroxisomal Beta Oxidation
    • Increased c9t11 CLA Production in Adipose Tissue
    • Altered Endocannabinoid System Function Due to Specific Strain
    • Modulated Endocannabinoid System

    • High evidence

  • Free-Radical Scavenging Activities of Cultured Mycelia of Paecilomyces hepiali (Ascomycetes) Extracts and Structural Characterization of Bioactive Components by Nuclear Magnetic Resonance Spectroscopy.

    • 2017-03-07
    • International Journal of Medicinal Mushrooms 18(10)
    • • Lucia Ungvarska Mal'ucka
      • J. Harvanová
      • M. Pavlík
      • Martin Rajtar
      • Lukas Jarosciak

    • PubMed: 27910757
    • DOI: 10.1615/INTJMEDMUSHROOMS.V18.I10.50

    1 Insight on

    • Enhanced Antioxidant Activity

    • Low evidence
• March 17

  • Vapor-fed bio-hybrid fuel cell.

    • 2017-03-17
    • Biotechnology for biofuels 10(1)
    • • Marcus S Benyamin
      • Justin P Jahnke
      • David M Mackie

    • PubMed: 28331544
    • DOI: 10.1186/s13068-017-0755-7

    2 Insights on

    • Reduced Fossil Fuel Dependence
    • Stable Long-Term Function

    • Low evidence
• March 27

  • Oral administration of Bifidobacterium bifidum G9-1 alleviates rotavirus gastroenteritis through regulation of intestinal homeostasis by inducing mucosal protective factors

    • 2017-03-27
    • Clinical Trial
    • PLOS ONE 12(3)
    • • Tomohiro Kawahara
      • Yutaka Makizaki
      • Yosuke Oikawa
      • Yoshiki Tanaka
      • Ayako Maeda
      • M. Shimakawa
      • S. Komoto
      • Kyoko Moriguchi
      • H. Ohno
      • K. Taniguchi

    • PubMed: 28346473
    • DOI: 10.1371/journal.pone.0173979

    7 Insights on

    • Reduced Small-Intestinal Damage
    • Improved Gut Permeability
    • Reduced RV-Induced Diarrhea
    • Reduced Infectious RV Titer
    • Enhanced Mucosal Protection
    • Improved Water Absorption
    • Normalized Osmotic Pressure in the Large Intestine

    • Low evidence
    • Rigorous Journal
    • Animal Study

  • Enhanced Probiotic Potential of Lactobacillus reuteri When Delivered as a Biofilm on Dextranomer Microspheres That Contain Beneficial Cargo

    • 2017-03-27
    • Clinical Trial
    • Frontiers in Microbiology 8
    • • J. Navarro
      • L. Mashburn-Warren
      • L. Bakaletz
      • M. Bailey
      • S. Goodman

    • PubMed: 28396655
    • DOI: 10.3389/fmicb.2017.00489

    6 Insights on

    • Increased Intestinal Epithelial Cell Adhesion
    • Increased Acid Resistance
    • Reduced Risk of Necrotizing Enterocolitis
    • Increased Histamine Production
    • Enhanced Adherence to Intestinal Epithelial Cells
    • Increased Production of Anti-inflammatory Histamine

    • Low evidence
    • Animal Study
• March 28

  • Early pregnancy probiotic supplementation with Lactobacillus rhamnosus HN001 may reduce the prevalence of gestational diabetes mellitus: a randomised controlled trial

    • 2017-03-28
    • RCT · n = 373
    • British Journal of Nutrition 117(6)
    • • K. Wickens
      • C. Barthow
      • R. Murphy
      • P. Abels
      • Robyn M. Maude
      • P. Stone
      • E. Mitchell
      • T. Stanley
      • G. Purdie
      • Janice Kang
      • Fiona Hood
      • Judy Rowden
      • Phillipa Barnes
      • P. Fitzharris
      • J. Crane

    • PubMed: 28367765
    • DOI: 10.1017/S0007114517000289

    1 Insight on

    • Reduced Prevalence of Gestational Diabetes Mellitus

    • High evidence
    • Large Human Trial
    • Highly Cited
• Undated – 4 supplement studies

  • Probiotics (Lactobacillus gasseri KS-13, Bifidobacterium bifidum G9-1, and Bifidobacterium longum MM-2) improve rhinoconjunctivitis-specific quality of life in individuals with seasonal allergies: a double-blind, placebo-controlled, randomized trial.

    • 2017-03
    • RCT · n = 173
    • The American Journal of Clinical Nutrition 105(3)
    • • J. C. Dennis-Wall
      • T. Culpepper
      • C. Nieves
      • C. Rowe
      • A. M. Burns
      • C. Rusch
      • A. Federico
      • M. Ukhanova
      • Sheldon Waugh
      • V. Mai
      • M. Christman
      • B. Langkamp-Henken

    • PubMed: 28228426
    • DOI: 10.3945/ajcn.116.140012

    1 Insight on

    • Improved Rhinoconjunctivitis-Specific Quality of Life

    • High evidence
    • Highly Cited

  • Beneficial effects of probiotic cholesterol-lowering strain of Enterococcus faecium WEFA23 from infants on diet-induced metabolic syndrome in rats.

    • 2017-03
    • Clinical Trial
    • Journal of Dairy Science 100(3)
    • • Fen Zhang
      • Liang Qiu
      • Xiongpeng Xu
      • Zhengqi Liu
      • Hui Zhan
      • X. Tao
      • N. Shah
      • Hua Wei

    • PubMed: 28041735
    • DOI: 10.3168/jds.2016-11870

    4 Insights on

    • Improved Insulin Sensitivity
    • Reduced Body Weight
    • Reduced Blood Glucose Levels
    • Reduced Lipid Levels

    • Low evidence
    • Rigorous Journal
    • Animal Study

  • Probiotic and antioxidant properties of selenium-enriched Lactobacillus brevis LSe isolated from an Iranian traditional dairy product.

    • 2017-03
    • Journal of Trace Elements in Medicine and Biology 40
    • • Mojtaba Shakibaie
      • Tayebe Mohammadi-Khorsand
      • Mahboubeh Adeli-sardou
      • M. Jafari
      • Sahar Amirpour-Rostami
      • A. Ameri
      • H. Forootanfar

    • PubMed: 28159215
    • DOI: 10.1016/j.jtemb.2016.11.013

    17 Insights on

    • Reduced Intestinal Cell Adhesion
    • Increased Antioxidant Activity
    • Improved Tolerance to Bile Salts
    • Improved Antioxidant Activity
    • Increased Selenium Tolerance
    • Increased Bile Salt Tolerance
    • Enhanced Antioxidant Activity
    • Improved Survival Through Gastric Conditions
    • Improved Resistance to Sodium Selenite
    • Maintained Cell Viability in Low pH
    • Maintained Viability in Presence of Bile Salts
    • Gastrointestinal Survival
    • Enhanced Radical Scavenging Ability
    • Increased Sodium Selenite Tolerance
    • Enhanced Antioxidant Capabilities
    • Improved Cell Adhesion
    • Improved Tolerance to Intestinal Conditions

    • Low evidence

  • Ability of Lactobacillus kefiri LKF01 (DSM32079) to colonize the intestinal environment and modify the gut microbiota composition of healthy individuals.

    • 2017-03
    • RCT · n = 20
    • Digestive and Liver Disease 49(3)
    • • Marco Toscano
      • R. De Grandi
      • V. Miniello
      • R. Mattina
      • L. Drago

    • PubMed: 27939319
    • DOI: 10.1016/j.dld.2016.11.011

    1 Insight on

    • Reduced Pro-Inflammatory Bacteria Levels

    • High evidence