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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Infective endocarditis caused by lactobacillus.
- 2008-07-29
- Case Report
- Internal Medicine 47(12)
- - S. Yagi
  - M. Akaike
  - M. Fujimura
  - T. Ise
  - S. Yoshida
  - Yuka Sumitomo
  - Yasumasa Ikeda
  - T. Iwase
  - K. Aihara
  - H. Azuma
  - A. Kurushima
  - Y. Ichikawa
  - T. Kitagawa
  - Takehiko Kimura
  - T. Nishiuchi
  - Toshio Matsumoto
- PubMed: 18552468
- DOI: 10.2169/INTERNALMEDICINE.47.0744
1 Insight on
- Development of Infective Endocarditis
- Low evidence
Influence of a combination of Lactobacillus acidophilus NCFM and lactitol on healthy elderly: intestinal and immune parameters.
- 2008-07-18
- RCT
- British Journal of Nutrition 101(3)
- - A. Ouwehand
  - K. Tiihonen
  - M. Saarinen
  - H. Putaala
  - N. Rautonen
- PubMed: 18634707
- DOI: 10.1017/S0007114508003097
3 Insights on
- High evidence
- Highly Cited
Effect of inulin on the human gut microbiota: stimulation of Bifidobacterium adolescentis and Faecalibacterium prausnitzii
- 2008-07-01
- British Journal of Nutrition 101(4)
- - Carlett Ramírez-Farías
  - K. Slezak
  - Zoë Fuller
  - A. Duncan
  - G. Holtrop
  - P. Louis
- PubMed: 18590586
- DOI: 10.1017/S0007114508019880
2 Insights on
- Increased Faecalibacterium prausnitzii Levels
- Increased Bifidobacterium adolescentis Levels
- Low evidence
- Highly Cited
Oral administration of heat-killed Lactobacillus brevis SBC8803 ameliorates the development of dermatitis and inhibits immunoglobulin E production in atopic dermatitis model NC/Nga mice.
- 2008-06-19
- Clinical Trial · n = 20
- Biological and Pharmaceutical Bulletin 31(5)
- - S. Segawa
  - Atsushi Hayashi
  - Y. Nakakita
  - H. Kaneda
  - J. Watari
  - H. Yasui
- PubMed: 18451512
- DOI: 10.1248/BPB.31.884
3 Insights on
- Low evidence
- Animal Study
Preliminary investigations of the colonisation of upper respiratory tract tissues of infants using a paediatric formulation of the oral probiotic Streptococcus salivarius K12
- 2008-06-17
- Clinical Trial · n = 19
- European Journal of Clinical Microbiology & Infectious Diseases 27(12)
- - Dan Power
  - Jeremy P. Burton
  - C. Chilcott
  - Patrick J. D. Dawes
  - J. Tagg
- PubMed: 18560907
- DOI: 10.1007/s10096-008-0569-4
3 Insights on
- High evidence
- Highly Cited
Probiotic products in Canada with clinical evidence: what can gastroenterologists recommend?
- 2008-06-03
- Review
- Canadian journal of gastroenterology = Journal canadien de gastroenterologie 22(2)
- - G Reid
  - K Anukam
  - T Koyama
- PubMed: 18299736
- DOI: 10.1155/2008/843892
1 Insight on
- Improved Gastrointestinal Health
- Low evidence
Comparative Genome Analysis of Lactobacillus reuteri and Lactobacillus fermentum Reveal a Genomic Island for Reuterin and Cobalamin Production
- 2008-05-12
- DNA Research 15(3)
- - H. Morita
  - Hidehiro Toh
  - S. Fukuda
  - H. Horikawa
  - K. Oshima
  - Takehito Suzuki
  - M. Murakami
  - S. Hisamatsu
  - Y. Kato
  - T. Takizawa
  - H. Fukuoka
  - T. Yoshimura
  - K. Itoh
  - D. O'sullivan
  - L. Mckay
  - H. Ohno
  - J. Kikuchi
  - T. Masaoka
  - M. Hattori
- PubMed: 18487258
- DOI: 10.1093/dnares/dsn009
2 Insights on
- Reduced Pathogen Growth
- Increased Vitamin B12 Levels
- Low evidence
- Highly Cited
Evaluation of the preventative effects exerted by Lactobacillus fermentum in an experimental model of septic shock induced in mice
- 2008-04-29
- Clinical Trial
- British Journal of Nutrition 101(1)
- - B. Arribas
  - M. Rodríguez-Cabezas
  - M. Comalada
  - E. Bailón
  - D. Camuesco
  - M. Olivares
  - J. Xaus
  - A. Zarzuelo
  - J. Gálvez
- PubMed: 18445307
- DOI: 10.1017/S0007114508986876
4 Insights on
- Low evidence
- Animal Study
Phase I Trial of a Lactobacillus crispatus Vaginal Suppository for Prevention of Recurrent Urinary Tract Infection in Women
- 2008-03-11
- RCT · n = 30
- Infectious Diseases in Obstetrics and Gynecology 2007
- - C. Czaja
  - A. Stapleton
  - Yuliya Yarova-Yarovaya
  - W. Stamm
- PubMed: 18288237
- DOI: 10.1155/2007/35387
12 Insights on
- High evidence
- Highly Cited
Effects of a probiotic Lactobacillus acidophilus strain on feed tolerance in dogs with non-specific dietary sensitivity
- 2008-03-04
- RCT · n = 6
- Archives of Animal Nutrition 62(2)
- - M. Pascher
  - P. Hellweg
  - A. Khol-Parisini
  - J. Zentek
- PubMed: 18459535
- DOI: 10.1080/17450390801892583
3 Insights on
- Low evidence
- Animal Study
Influence of probiotic Lactobacillus acidophilus and L. helveticus on proteolysis, organic acid profiles, and ACE-inhibitory activity of cheddar cheeses ripened at 4, 8, and 12 degrees C.
- 2008-03-03
- Journal of Food Science 73(3)
- - L. Ong
  - N. Shah
- PubMed: 18387113
- DOI: 10.1111/j.1750-3841.2008.00689.x
3 Insights on
- Low evidence
Therapeutic Effect of Lactobacillus acidophilus-SDC 2012, 2013 in Patients with Irritable Bowel Syndrome
- 2008-02-15
- RCT · n = 40
- Digestive Diseases and Sciences 53(10)
- - D. Sinn
  - J. Song
  - Hoi-Jin Kim
  - J. Lee
  - H. Son
  - D. Chang
  - Young-Ho Kim
  - Jae J Kim
  - J. Rhee
  - P. Rhee
- PubMed: 18274900
- DOI: 10.1007/s10620-007-0196-4
2 Insights on
- Reduced Abdominal Discomfort
- Increased Proportion of Responders
- High evidence
- Highly Cited
Immunomodulatory effect of halophilic lactic acid bacterium Tetragenococcus halophilus Th221 from soy sauce moromi grown in high-salt medium.
- 2008-02-10
- International Journal of Food Microbiology 121(3)
- - S. Masuda
  - H. Yamaguchi
  - T. Kurokawa
  - T. Shirakami
  - R. Tsuji
  - I. Nishimura
- PubMed: 18061297
- DOI: 10.1016/J.IJFOODMICRO.2007.10.011
5 Insights on
- Low evidence
Probiotic lactobacilli and VSL#3 induce enterocyte β‐defensin 2
- 2008-01-09
- Clinical and Experimental Immunology 151(3)
- - M. Schlee
  - J. Harder
  - B. Köten
  - E. Stange
  - J. Wehkamp
  - J. Wehkamp
  - K. Fellermann
- PubMed: 18190603
- DOI: 10.1111/j.1365-2249.2007.03587.x
1 Insight on
- Improved Intestinal Barrier Function
- Low evidence
- Highly Cited
Effects of Lactobacillus salivarius 433118 on Intestinal Inflammation, Immunity Status and In vitro Colon Function in Two Mouse Models of Inflammatory Bowel Disease
- 2007-12-20
- Clinical Trial
- Digestive Diseases and Sciences 53(9)
- - L. Feighery
  - Philip Smith
  - L. O’Mahony
  - P. Fallon
  - David J Brayden
- PubMed: 18157694
- DOI: 10.1007/s10620-007-0157-y
2 Insights on
- Reduced Inflammatory Response
- Increased Cytokine Response
- Low evidence
- Animal Study
Stimulation of indigenous lactobacilli by fermented milk prepared with probiotic bacterium, Lactobacillus delbrueckii subsp. bulgaricus strain 2038, in the pigs.
- 2007-12-03
- Clinical Trial · n = 3
- Journal of Nutritional Science and Vitaminology 53(1)
- - Y. Ohashi
  - M. Tokunaga
  - N. Taketomo
  - K. Ushida
- PubMed: 17484385
- DOI: 10.3177/JNSV.53.82
2 Insights on
- Increased Fecal Lactobacilli
- Altered Lactobacilli Composition
- Low evidence
- Animal Study
The effect of yeast (Saccharomyces cerevisiae) on nutrient intake, digestibility and finishing performance of lambs fed a diet based on dried molasses sugar beet-pulp.
- 2007-12-01
- RCT · n = 18
- Pakistan Journal of Biological Sciences 10(24)
- - S. Payandeh
  - F. Kafilzadeh
- PubMed: 19093506
- DOI: 10.3923/PJBS.2007.4426.4431
3 Insights on
- Low evidence
- Animal Study
Lactobacillus Acidophilus strain L-92 regulates the production of Th1 cytokine as well as Th2 cytokines.
- 2007-11-29
- Clinical Trial
- Allergology International 56(3)
- - Akiko Torii
  - S. Torii
  - S. Fujiwara
  - Hiroyuki Tanaka
  - N. Inagaki
  - H. Nagai
- PubMed: 17646735
- DOI: 10.2332/ALLERGOLINT.O-06-459
2 Insights on
- Reduced Serum OVA-specific IgE Levels
- Increased IgA Production by PPs
- Low evidence
- Highly Cited
- Animal Study
Lactobacillus rhamnosus R11 Consumed in a Food Supplement Survived Human Digestive Transit without Modifying Microbiota Equilibrium as Assessed by Real-Time Polymerase Chain Reaction
- 2007-10-24
- Clinical Trial · n = 14
- Microbial Physiology 14(1-3)
- - O. Firmesse
  - A. Mogenet
  - J. Bresson
  - G. Corthier
  - J. Furet
- PubMed: 17957115
- DOI: 10.1159/000106087
2 Insights on
- Improved Survival Through Digestive Tract
- Maintained Microbiota Equilibrium
- Moderate evidence
An Experimental Study and a Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Evaluate the Antisecretory Activity of Lactobacillus acidophilus Strain LB Against Nonrotavirus Diarrhea
- 2007-10-01
- RCT
- Pediatrics 120(4)
- - Vanessa Lievin-Le Moal
  - Luis E Sarrazin-Davila
  - A. Servin
- PubMed: 17768180
- DOI: 10.1542/peds.2006-2930
1 Insight on
- Reduced Recovery Time for Diarrhea
- High evidence
- Highly Cited
Influence of Bifidobacterium longum BB536 intake on faecal microbiota in individuals with Japanese cedar pollinosis during the pollen season.
- 2007-10-01
- RCT · n = 58
- Journal of Medical Microbiology 56(10)
- - T. Odamaki
  - J. Xiao
  - N. Iwabuchi
  - M. Sakamoto
  - N. Takahashi
  - S. Kondo
  - K. Miyaji
  - K. Iwatsuki
  - H. Togashi
  - T. Enomoto
  - Y. Benno
- PubMed: 17893165
- DOI: 10.1099/JMM.0.47306-0
4 Insights on
- High evidence
A probiotic lozenge administered medical device and its effect on salivary mutans streptococci and lactobacilli.
- 2007-08-21
- RCT · n = 20
- International Journal of Paediatric Dentistry 18(1)
- - E. Çaglar
  - O. Kuscu
  - S. Cildir
  - Senem Selui Kuvvetli
  - N. Sandalli
- PubMed: 18086024
- DOI: 10.1111/J.1365-263X.2007.00866.X
1 Insight on
- Reduced Salivary Levels of Mutans Streptococci
- High evidence
- Highly Cited
Efficacy and Safety of Saccharomyces boulardii in the 14‐day Triple Anti‐Helicobacter pylori Therapy: A Prospective Randomized Placebo‐Controlled Double‐Blind Study
- 2007-07-30
- RCT
- Helicobacter 12(4)
- - M. Cindoruk
  - Gulbanu Erkan
  - T. Karakan
  - A. Dursun
  - S. Unal
- PubMed: 17669103
- DOI: 10.1111/j.1523-5378.2007.00516.x
6 Insights on
- High evidence
- Highly Cited
Survival and persistence of Lactobacillus plantarum 4.1 and Lactobacillus reuteri 3S7 in the gastrointestinal tract of pigs.
- 2007-07-20
- Clinical Trial
- Veterinary Microbiology 123(1-3)
- - M. De Angelis
  - S. Siragusa
  - L. Caputo
  - A. Ragni
  - R. Burzigotti
  - M. Gobbetti
- PubMed: 17391871
- DOI: 10.1016/J.VETMIC.2007.02.022
2 Insights on
- Reduced Enterobacteriaceae Counts
- Reduced Beta-Glucuronidase Activity
- Low evidence
- Animal Study
Casein fermentate of Lactobacillus animalis DPC6134 contains a range of novel propeptide angiotensin-converting enzyme inhibitors.
- 2007-07-15
- n = 72
- Applied and environmental microbiology 73(14)
- - M Hayes
  - C Stanton
  - H Slattery
  - O O'Sullivan
  - C Hill
  - G F Fitzgerald
  - R P Ross
- PubMed: 17483275
- DOI: 10.1128/aem.00096-07
2 Insights on
- Reduced Angiotensin I-Converting Enzyme Activity
- Identified ACE-Inhibitory Peptides
- Low evidence
- Rigorous Journal
- Animal Study
Effect of Lactobacillus plantarum enteral feeding on the gut permeability and septic complications in the patients with acute pancreatitis
- 2007-06-20
- RCT · n = 76
- European Journal of Clinical Nutrition 62(7)
- - H. Qin
  - J-J Zheng
  - D. Tong
  - W-X Chen
  - Xiao-bing Fan
  - X-M Hang
  - Y.-Q. Jiang
- PubMed: 17579653
- DOI: 10.1038/sj.ejcn.1602792
9 Insights on
- High evidence
- Highly Cited
- Rigorous Journal
Clinical efficacy of probiotic Bifidobacterium longum for the treatment of symptoms of Japanese cedar pollen allergy in subjects evaluated in an environmental exposure unit.
- 2007-06-05
- RCT · n = 24
- Allergology International 56(1)
- - J. Xiao
  - S. Kondo
  - N. Yanagisawa
  - K. Miyaji
  - Keisuke Enomoto
  - Takema Sakoda
  - K. Iwatsuki
  - T. Enomoto
- PubMed: 17259812
- DOI: 10.2332/ALLERGOLINT.O-06-455
3 Insights on
- High evidence
Anti-inflammatory effects of Lactobacillus brevis (CD2) on periodontal disease.
- 2007-05-23
- Clinical Trial · n = 29
- Oral Diseases 13(4)
- - D. Riccia
  - F. Bizzini
  - M. Perilli
  - A. Polimeni
  - V. Trinchieri
  - G. Amicosante
  - M. Cifone
- PubMed: 17577323
- DOI: 10.1111/J.1601-0825.2006.01291.X
5 Insights on
- High evidence
- Highly Cited
Intake of fermented soybean (natto) increased locomotor activity in mice.
- 2007-05-22
- Clinical Trial
- Biological and Pharmaceutical Bulletin 30(4)
- - T. Mamiya
  - A. Nishimura
- PubMed: 17409536
- DOI: 10.1248/BPB.30.845
1 Insight on
- Increased Locomotor Activity During Active Phase
- Low evidence
- Animal Study
A new synbiotic consisting of Lactobacillus casei subsp. casei and dextran improves milk production in Holstein dairy cows.
- 2007-04-19
- RCT · n = 58
- Journal of Veterinary Medical Science 69(2)
- - K. Yasuda
  - Shin-nosuke Hashikawa
  - H. Sakamoto
  - Y. Tomita
  - S. Shibata
  - T. Fukata
- PubMed: 17339767
- DOI: 10.1292/JVMS.69.205
7 Insights on
- Low evidence
- Animal Study