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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Investigating the anti‐inflammatory effects of high molecular weight secretions from Limosilactobacillus reuteri PTCC 1655 on LPS‐stimulated PMA‐differentiated THP‐1 cells
- 2021-01-11
- Journal of Applied Microbiology 131(2)
- - Behrooz Johari
  - Faezeh Maghsood
  - H. Madanchi
  - M. Moradi
  - M. Kadivar
- PubMed: 33377567
- DOI: 10.1111/jam.14984
1 Insight on
- Reduced Inflammation Levels
- Low evidence
Interventions for treating leg ulcers in people with sickle cell disease.
- 2021-01-09
- Systematic Review · n = 198
- The Cochrane database of systematic reviews 2021(1)
- - Arturo J Martí-Carvajal
  - Jennifer M Knight-Madden
  - Maria José Martinez-Zapata
- PubMed: 34559425
- DOI: 10.1002/14651858.cd008394.pub4
2 Insights on
- Reduced Ulcer Size
- Improved Leg Ulcer Healing
- High evidence
Effect of Oral Administration with Lactobacillus plantarum CAM6 Strain on Sows during Gestation-Lactation and the Derived Impact on Their Progeny Performance
- 2021-01-08
- RCT · n = 20
- Mediators of Inflammation 2021
- - C. Betancur
  - Y. Martínez
  - G. Téllez-Isaías
  - Rogel Castillo
  - Xinghua Ding
- PubMed: 33505214
- DOI: 10.1155/2021/6615960
8 Insights on
- Low evidence
- Rigorous Journal
- Animal Study
Effect of probiotic Lactobacillus plantarum Dad-13 powder consumption on the gut microbiota and intestinal health of overweight adults
- 2021-01-07
- RCT · n = 60
- World Journal of Gastroenterology 27(1)
- - E. Rahayu
  - M. Mariyatun
  - Nancy Eka Putri Manurung
  - P. N. Hasan
  - Phatthanaphong Therdtatha
  - Riko Mishima
  - Husnita Komalasari
  - N. A. Mahfuzah
  - F. H. Pamungkaningtyas
  - Wahyu Krisna Yoga
  - Dina Aulia Nurfiana
  - Stefanie Yolanda Liwan
  - M. Juffrie
  - A. Nugroho
  - T. Utami
- PubMed: 33505154
- DOI: 10.3748/wjg.v27.i1.107
3 Insights on
- High evidence
- Rigorous Journal
The In Vitro Adsorption Ability of Lactobacillus acidophilus NCFM to Benzo(a)pyrene in PM2.5
- 2021-01-07
- Journal of Toxicology 2021
- - L. Fu
  - Y. Ning
  - Hongfei Zhao
  - Junfeng Fan
  - Bolin Zhang
- PubMed: 33505465
- DOI: 10.1155/2021/6290524
1 Insight on
- Reduced Benzo(a)pyrene Levels
- Low evidence
- Rigorous Journal
Exercise associated or not to the intake of Eurycoma longifolia improves strength and cardiorespiratory fitness in men with androgen deficiency.
- 2021-01-05
- RCT · n = 12
- Complementary therapies in clinical practice 42
- - Alice Erwig Leitão
  - Melissa de Carvalho Souza Vieira
  - Diogo Almeida Gomes
  - Leonessa Boing
  - Andreia Pelegrini
  - Edson Luiz
  - Adriana Coutinho de Azevedo Guimarães
- PubMed: 33445146
- DOI: 10.1016/j.ctcp.2020.101301
3 Insights on
- High evidence
Effects of intragastric administration of L-tryptophan on the glycaemic response to a nutrient drink in men with type 2 diabetes - impacts on gastric emptying, glucoregulatory hormones and glucose absorption.
- 2021-01-05
- RCT
- Nutrition & diabetes 11(1)
- - Maryam Hajishafiee
  - Rachel A Elovaris
  - Karen L Jones
  - Leonie K Heilbronn
  - Michael Horowitz
  - Sally D Poppitt
  - Christine Feinle-Bisset
- PubMed: 33414406
- DOI: 10.1038/s41387-020-00146-9
11 Insights on
- High evidence
Prophylactic effect of Lactobacillus plantarum KSFY06 on HCl/ethanol-induced gastric injury in mice.
- 2021-01-04
- Food & Function 11(3)
- - Ranran Wang
  - Xiaofei Zeng
  - Bihui Liu
  - Ruokun Yi
  - Xianrong Zhou
  - Jianfei Mu
  - Xin Zhao
- PubMed: 32162630
- DOI: 10.1039/c9fo02474c
5 Insights on
- Low evidence
A 5-year longitudinal association between dietary fermented soya bean (natto) intake and tooth loss through bone mineral density in postmenopausal women: The Yokogoshi cohort study.
- 2021-01-04
- Observational · n = 435
- Gerodontology 38(3)
- - M. Iwasaki
  - Misuzu Sato
  - A. Yoshihara
  - Toshiko Saito
  - K. Kitamura
  - T. Ansai
  - Kazutoshi Nakamura
- PubMed: 33393717
- DOI: 10.1111/ger.12523
1 Insight on
- Reduced Tooth Loss
- High evidence
An Exopolysaccharide Produced by Bifidobacterium longum 35624® Inhibits Osteoclast Formation via a TLR2-Dependent Mechanism
- 2021-01-03
- Calcified Tissue International 108(5)
- - A. Wallimann
  - M. Hildebrand
  - D. Groeger
  - B. Stanić
  - C. Akdis
  - S. Zeiter
  - R. G. Richards
  - T. F. Moriarty
  - L. O’Mahony
  - K. Thompson
- PubMed: 33388801
- DOI: 10.1007/s00223-020-00790-4
3 Insights on
- Low evidence
- Rigorous Journal
Broad Spectrum Polyphenol Supplementation from Tart Cherry Extract on Markers of Recovery from Intense Resistance Exercise.
- 2021-01-02
- RCT
- Journal of the International Society of Sports Nutrition 18(1)
- - D R Hooper
  - T Orange
  - M T Gruber
  - A A Darakjian
  - K L Conway
  - H A Hausenblas
- PubMed: 34126996
- DOI: 10.1186/s12970-021-00449-x
6 Insights on
- High evidence
Butyrate-producing human gut symbiont, Clostridium butyricum, and its role in health and disease
- 2021-01-01
- Review
- Gut Microbes 13(1)
- - Magdalena K. Stoeva
  - Jeewon Garcia-So
  - N. Justice
  - J. Myers
  - Surabhi Tyagi
  - Madeleine Nemchek
  - Paul J. McMurdie
  - O. Kolterman
  - J. Eid
- PubMed: 33874858
- DOI: 10.1080/19490976.2021.1907272
7 Insights on
- High evidence
- Highly Cited
- Rigorous Journal
Effects of Lactobacillus rhamnosus GG on early postoperative outcome after pylorus-preserving pancreatoduodenectomy: a randomized trial.
- 2021-01-01
- RCT · n = 20
- European review for medical and pharmacological sciences 25(1)
- - M Folwarski
  - M Dobosz
  - S Małgorzewicz
  - K Skonieczna-Żydecka
  - K Kaźmierczak-Siedlecka
- PubMed: 33506929
- DOI: 10.26355/eurrev_202101_24407
7 Insights on
- High evidence
Effects of Triphala on Lipid and Glucose Profiles and Anthropometric Parameters: A Systematic Review.
- 2021-01-01
- Systematic Review · n = 749
- Journal of evidence-based integrative medicine 26
- - Wiraphol Phimarn
  - Bunleu Sungthong
  - Hiroyuki Itabe
- PubMed: 33886393
- DOI: 10.1177/2515690x211011038
7 Insights on
- High evidence
Safety and efficacy of using heat-killed Lactobacillus plantarum L-137: High-dose and long-term use effects on immune-related safety and intestinal bacterial flora
- 2021-01-01
- Clinical Trial · n = 44
- Journal of Immunotoxicology 18(1)
- - Hiroko Nakai
  - S. Murosaki
  - Yoshihiro Yamamoto
  - M. Furutani
  - R. Matsuoka
  - Y. Hirose
- PubMed: 34559598
- DOI: 10.1080/1547691X.2021.1979698
4 Insights on
- High evidence
Fermentative Foods: Microbiology, Biochemistry, Potential Human Health Benefits and Public Health Issues.
- 2020-12-31
- Review
- Foods (Basel, Switzerland) 10(1)
- - Chrysa Voidarou
  - Μaria Antoniadou
  - Georgios Rozos
  - Athina Tzora
  - Ioannis Skoufos
  - Theodoros Varzakas
  - Areti Lagiou
  - Eugenia Bezirtzoglou
- PubMed: 33396397
- DOI: 10.3390/foods10010069
2 Insights on
- Improved Gastrointestinal Health
- Improved Immune Function
- Low evidence
Probiogenomics Analysis of 97 Lactobacillus crispatus Strains as a Tool for the Identification of Promising Next-Generation Probiotics
- 2020-12-30
- Microorganisms 9(1)
- - Federico Fontana
  - Giulia Alessandri
  - G. Lugli
  - Leonardo Mancabelli
  - G. Longhi
  - R. Anzalone
  - Alice Viappiani
  - M. Ventura
  - F. Turroni
  - C. Milani
- PubMed: 33396617
- DOI: 10.3390/microorganisms9010073
1 Insight on
- Increased Vaginal Lactobacilli Levels
- Low evidence
- Rigorous Journal
L-lysine therapy to control the clinical evolution of pityriasis rosea: Clinical case report and literature review.
- 2020-12-30
- Review
- Dermatologic therapy 34(1)
- - Maria Cristina Pedrazini
  - Francisco Carlos Groppo
- PubMed: 33326128
- DOI: 10.1111/dth.14679
3 Insights on
- Low evidence
Evaluation of the Effect of Probiotic Bacillus coagulans Unique IS2 on Mutans Streptococci and Lactobacilli Levels in Saliva and Plaque: A Double-Blind, Randomized, Placebo-Controlled Study in Children
- 2020-12-29
- RCT · n = 48
- International Journal of Dentistry 2020
- - M. Ratna Sudha
  - J. Neelamraju
  - M. Surendra Reddy
  - Manoj Kumar
- PubMed: 33456469
- DOI: 10.1155/2020/8891708
4 Insights on
- High evidence
- Rigorous Journal
Comparative evaluation for thermostability and gastrointestinal survival of probiotic Bacillus coagulans MTCC 5856.
- 2020-12-24
- Bioscience, Biotechnology, and Biochemistry 85(4)
- - M. Majeed
  - Shaheen Majeed
  - S. Arumugam
  - Furqan Ali
  - Kirankumar Beede
- PubMed: 33580694
- DOI: 10.1093/bbb/zbaa116
3 Insights on
- Low evidence
Plasma Amino Acid Response to Whey Protein Ingestion Following 28 Days of Probiotic (Bacillus subtilis DE111) Supplementation in Active Men and Women
- 2020-12-23
- RCT · n = 22
- Journal of Functional Morphology and Kinesiology 6(1)
- - Jeremy R. Townsend
  - William C. Vantrease
  - Megan D Jones
  - Philip A. Sapp
  - Kent D. Johnson
  - Cheryle N. Beuning
  - Allison A. Haase
  - C. Boot
- PubMed: 33462163
- DOI: 10.3390/jfmk6010001
1 Insight on
- Unchanged Plasma Amino Acid Response
- High evidence
Lactobacillus plantarum KLDS1.0344 and Lactobacillus acidophilus KLDS1.0901 Mixture Prevents Chronic Alcoholic Liver Injury in Mice by Protecting the Intestinal Barrier and Regulating Gut Microbiota and Liver-Related Pathways.
- 2020-12-22
- Clinical Trial
- Journal of Agricultural and Food Chemistry 69(1)
- - Huizhen Li
  - Jialu Shi
  - Li Zhao
  - Jiaqi Guan
  - Fei Liu
  - G. Huo
  - Bailiang Li
- PubMed: 33353302
- DOI: 10.1021/acs.jafc.0c06346
12 Insights on
- Low evidence
- Animal Study
Efficacy of Lactiplantibacillus plantarum 299 and 299v against nosocomial oropharyngeal pathogens in vitro and as an oral prophylactic treatment in a randomized, controlled clinical trial
- 2020-12-22
- RCT
- MicrobiologyOpen 10(1)
- - A. Tranberg
  - Bengt Klarin
  - Julia Johansson
  - L. Påhlman
- PubMed: 33350604
- DOI: 10.1002/mbo3.1151
3 Insights on
- High evidence
No Effect of Dietary Fish Oil Supplementation on the Recruitment of Brown and Brite Adipocytes in Mice or Humans under Thermoneutral Conditions.
- 2020-12-21
- RCT
- Molecular nutrition & food research 65(2)
- - Stefanie F Maurer
  - Sebastian Dieckmann
  - Jens Lund
  - Tobias Fromme
  - Anne Lundby Hess
  - Cécilia Colson
  - Louise Kjølbaek
  - Arne Astrup
  - Matthew Paul Gillum
  - Lesli Hingstrup Larsen
  - Gerhard Liebisch
  - Ez-Zoubir Amri
  - Martin Klingenspor
- PubMed: 33274552
- DOI: 10.1002/mnfr.202000681
1 Insight on
- Increased Thermogenic Adipocyte Recruitment
- High evidence
- Rigorous Journal
Passiflora incarnata in Neuropsychiatric Disorders-A Systematic Review.
- 2020-12-19
- Systematic Review
- Nutrients 12(12)
- - Katarzyna Janda
  - Karolina Wojtkowska
  - Karolina Jakubczyk
  - Justyna Antoniewicz
  - Karolina Skonieczna-Żydecka
- PubMed: 33352740
- DOI: 10.3390/nu12123894
4 Insights on
- High evidence
- Rigorous Journal
Eukaryotic and Prokaryotic Microbiota Interactions.
- 2020-12-17
- Review
- Microorganisms 8(12)
- - Aly Kodio
  - Estelle Menu
  - Stéphane Ranque
- PubMed: 33348551
- DOI: 10.3390/microorganisms8122018
2 Insights on
- Improved Overall Health Status
- Improved Glycemia
- Low evidence
Feeding Limosilactobacillus fermentum K9-2 and Lacticaseibacillus casei K9-1, or Limosilactobacillus reuteri TMW1.656 Reduces Pathogen Load in Weanling Pigs
- 2020-12-17
- Clinical Trial
- Frontiers in Microbiology 11
- - Weilan Wang
  - R. Zijlstra
  - M. Gänzle
- PubMed: 33391231
- DOI: 10.3389/fmicb.2020.608293
1 Insight on
- Reduced Enterotoxigenic Escherichia coli Abundance
- Low evidence
- Animal Study
Lactobacillus salivarius, a Potential Probiotic to Improve the Health of LPS-Challenged Piglet Intestine by Alleviating Inflammation as Well as Oxidative Stress in a Dose-Dependent Manner During Weaning Transition
- 2020-12-16
- RCT · n = 72
- Frontiers in Veterinary Science 7
- - Zeyang Sun
  - Haihua Li
  - Yupeng Li
  - J. Qiao
- PubMed: 33392276
- DOI: 10.3389/fvets.2020.547425
22 Insights on
- Low evidence
- Animal Study
Nutritional Interventions to Improve Asthma-Related Outcomes through Immunomodulation: A Systematic Review.
- 2020-12-16
- Systematic Review
- Nutrients 12(12)
- - Lieve van Brakel
  - Ronald P Mensink
  - Geertjan Wesseling
  - Jogchum Plat
- PubMed: 33339167
- DOI: 10.3390/nu12123839
4 Insights on
- High evidence
- Rigorous Journal
Effect of Kefir on Soybean Isoflavone Aglycone Content in Soymilk Kefir
- 2020-12-16
- Frontiers in Nutrition 7
- - Minke Yang
  - Xiaojuan Yang
  - Xiaoqu Chen
  - Jie Wang
  - Zhenlin Liao
  - Li Wang
  - Qingping Zhong
  - Xiang Fang
- PubMed: 33392237
- DOI: 10.3389/fnut.2020.587665
1 Insight on
- Improved Isoflavone Biotransformation
- Low evidence