December 2013 Supplement Research Papers

• December 3

  • Effect of Lactobacillus rhamnosus CGMCC1.3724 supplementation on weight loss and maintenance in obese men and women

    • 2013-12-03
    • RCT
    • British Journal of Nutrition 111(8)
    • • Marina Sánchez
      • C. Darimont
      • V. Drapeau
      • S. Emady-Azar
      • Mélissa Lepage
      • E. Rezzonico
      • C. Ngom-Bru
      • B. Berger
      • Lionel Philippe
      • Corinne Ammon-Zuffrey
      • P. Leone
      • Geneviève Chevrier
      • Emmanuelle St-Amand
      • A. Marette
      • Jean Doré
      • A. Tremblay

    • PubMed: 24299712
    • DOI: 10.1017/S0007114513003875

    7 Insights on

    • Reduced Leptin Levels
    • Reduced Body Weight
    • Reduced Body Fat Mass
    • Maintained Weight
    • Reduced Blood Leptin Levels
    • Modulated Gut Microbiota
    • Reduced Circulating Leptin Concentrations

    • High evidence
    • Highly Cited
• December 10

  • Modulatory effects of Bifidobacterium longum BB536 on defecation in elderly patients receiving enteral feeding.

    • 2013-12-10
    • RCT · n = 206
    • World Journal of Gastroenterology 19(14)
    • • Junko Kondo
      • J. Xiao
      • A. Shirahata
      • Mieko Baba
      • Akie Abe
      • Koichi Ogawa
      • T. Shimoda

    • PubMed: 23599642
    • DOI: 10.3748/wjg.v19.i14.2162

    17 Insights on

    • Improved Bowel Movement Frequency
    • Increased Bowel Movement Frequency
    • Increased Gut Bifidobacteria
    • Increased Fecal Bifidobacteria Levels
    • Improved Intestinal Microenvironment
    • Increased Prevalence of Normally Formed Stools
    • Increased Bifidobacteria Levels in Gut Microbiota
    • Reduced Bowel Movements
    • Increased Bowel Movements
    • Increased Bifidobacteria in Fecal Microbiota
    • Improved Bowel Movements
    • Improved Stool Formation
    • Increased Bowel Movement Regularity
    • Reduced Bowel Movement Frequency
    • Increased Body Temperature
    • Increased Normal Stool Consistency
    • Increased Infection Frequency

    • High evidence
    • Rigorous Journal
• December 13

  • Effect of probiotics on biomarkers of cardiovascular disease: implications for heart-healthy diets.

    • 2013-12-13
    • Meta-Analysis
    • Nutrition Reviews 72(1)
    • • D. Dirienzo

    • PubMed: 24330093
    • DOI: 10.1111/nure.12084

    6 Insights on

    • Reduced Total Cholesterol Levels
    • Reduced Inflammatory Markers
    • Reduced Risk of Coronary Heart Disease
    • Reduced LDL Cholesterol
    • Improved Inflammatory Biomarkers
    • Reduced Total Cholesterol

    • High evidence
    • Highly Cited
• December 20

  • Meta‐analysis shows limited evidence for using Lactobacillus acidophilus LB to treat acute gastroenteritis in children

    • 2013-12-20
    • Meta-Analysis
    • Acta Paediatrica 103(3)
    • • H. Szajewska
      • M. Ruszczyński
      • S. Kolaček

    • PubMed: 24175943
    • DOI: 10.1111/apa.12487

    3 Insights on

    • Reduced Duration of Hospitalized Diarrhea in Children
    • Improved Cure Rate on Day Four
    • Unchanged Duration of Diarrhoea in Outpatient Children

    • High evidence
• December 30

  • Probiotic gut effect prevents the chronic psychological stress‐induced brain activity abnormality in mice

    • 2013-12-30
    • Clinical Trial
    • Neurogastroenterology & Motility 26(4)
    • • A. Ait-Belgnaoui
      • A. Colom
      • V. Braniste
      • L. Ramalho
      • A. Marrot
      • C. Cartier
      • E. Houdeau
      • V. Théodorou
      • T. Tompkins

    • PubMed: 24372793
    • DOI: 10.1111/nmo.12295

    4 Insights on

    • Enhanced Tight Junction Integrity
    • Reduced cFos Expression in Brain Areas
    • Preserved Hippocampal Neurogenesis
    • Reduced Abnormal Brain Plasticity Due to Stress

    • Low evidence
    • Highly Cited
    • Animal Study
• Undated – 8 supplement studies

  • Lactobacillus salivarius: bacteriocin and probiotic activity.

    • 2013-12
    • Food Microbiology 36(2)
    • • Soumaya Messaoudi
      • M. Manai
      • Gilles Kergourlay
      • H. Prévost
      • N. Connil
      • J. Chobert
      • X. Dousset

    • PubMed: 24010610
    • DOI: 10.1016/j.fm.2013.05.010

    4 Insights on

    • Increased Antibacterial Activity
    • Enhanced Food Safety
    • Increased Probiotic Consumption
    • Increased Antibiotic Use

    • Low evidence
    • Highly Cited

  • A comparison of two probiotic strains of bifidobacteria in premature infants.

    • 2013-12
    • RCT · n = 21
    • The Journal of Pediatrics 163(6)
    • • M. Underwood
      • K. Kalanetra
      • Nicholas A. Bokulich
      • Zachery T Lewis
      • M. Mirmiran
      • D. Tancredi
      • D. Mills

    • PubMed: 23993139
    • DOI: 10.1016/j.jpeds.2013.07.017

    3 Insights on

    • Increased Fecal Bifidobacteria Levels
    • Improved Gut Bacterial Diversity
    • Reduced γ-Proteobacteria Levels in Human Milk-Fed Infants

    • High evidence
    • Highly Cited

  • Effect of Lactobacillus salivarius Ls-33 on fecal microbiota in obese adolescents.

    • 2013-12
    • RCT · n = 50
    • Clinical Nutrition 32(6)
    • • N. Larsen
      • F. Vogensen
      • R. Gøbel
      • K. Michaelsen
      • S. Forssten
      • S. Lahtinen
      • M. Jakobsen

    • PubMed: 23510724
    • DOI: 10.1016/j.clnu.2013.02.007

    3 Insights on

    • Increased Short Chain Fatty Acids
    • Modified Fecal Microbiota
    • Unchanged Cell Numbers of Fecal Bacteria

    • High evidence
    • Highly Cited

  • Efficacy of Saccharomyces boulardii on necrotizing enterocolitis or sepsis in very low birth weight infants: a randomised controlled trial.

    • 2013-12
    • RCT · n = 208
    • Early Human Development 89(12)
    • • O. Serce
      • D. Benzer
      • T. Gursoy
      • G. Karatekin
      • F. Ovalı

    • PubMed: 24041815
    • DOI: 10.1016/j.earlhumdev.2013.08.013

    2 Insights on

    • Time to Full Enteral Feeding in Postnatal Age
    • Incidence of Necrotizing Enterocolitis

    • High evidence
    • Highly Cited

  • Antipathogenic activity of probiotics against Salmonella Typhimurium and Clostridium difficile in anaerobic batch culture systems: is it due to synergies in probiotic mixtures or the specificity of single strains?

    • 2013-12
    • Anaerobe 24
    • • Sandra Tejero-Sariñena
      • J. Barlow
      • A. Costabile
      • G. Gibson
      • I. Rowland

    • PubMed: 24091275
    • DOI: 10.1016/j.anaerobe.2013.09.011

    2 Insights on

    • Reduced Fecal Clostridium Levels
    • Reduced Salmonella Typhimurium Counts

    • Low evidence

  • The effect of Pediococcus acidilactici bacteria used as probiotic supplement on the growth and non-specific immune responses of green terror, Aequidens rivulatus.

    • 2013-12
    • RCT · n = 60
    • Fish & Shellfish Immunology 35(6)
    • • Alireza Neissi
      • G. Rafiee
      • M. Nematollahi
      • O. Safari

    • PubMed: 24161762
    • DOI: 10.1016/j.fsi.2013.09.036

    8 Insights on

    • Increased Serum Lysozyme Activity
    • Improved Immune Function
    • Improved Immune Response
    • Improved Growth Performance
    • Increased Immunoglobulin Levels
    • Improved Immunological Indices
    • Improved Alternative Complement Pathway Activity
    • Improved Growth Indices

    • Low evidence
    • Animal Study

  • Effects of Lactobacillus kefiranofaciens M1 isolated from kefir grains on enterohemorrhagic Escherichia coli infection using mouse and intestinal cell models.

    • 2013-12
    • Clinical Trial
    • Journal of Dairy Science 96(12)
    • • Yen-Po Chen
      • T. Y. Lee
      • W. Hong
      • H. Hsieh
      • Ming-Ju Chen

    • PubMed: 24140320
    • DOI: 10.3168/jds.2013-7015

    3 Insights on

    • Protection Against Intestinal Epithelial Injury
    • Reduced EHEC Infection Symptoms
    • Increased Mucosal EHEC-Specific IgA Responses

    • Low evidence
    • Animal Study

  • Commercially available probiotic drinks containing Lactobacillus casei DN-114001 reduce antibiotic-associated diarrhea.

    • 2014
    • World Journal of Gastroenterology 20(42)
    • • C. Dietrich
      • T. Kottmann
      • Manuela Alavi

    • PubMed: 25400470
    • DOI: 10.3748/wjg.v20.i42.15837

    3 Insights on

    • Reduced Incidence of Antibiotic-Associated Diarrhea
    • Reduced Duration of Antibiotic-Associated Diarrhea
    • Reduced Cost-Effectiveness in Reducing AAD

    • Low evidence
    • Rigorous Journal