February 2016 Supplement Research Papers

• February 1

  • Bifidobacterium breve prevents necrotising enterocolitis by suppressing inflammatory responses in a preterm rat model.

    • 2016-02-01
    • Clinical Trial
    • Beneficial Microbes 7(1)
    • • T. Satoh
      • H. Izumi
      • N. Iwabuchi
      • T. Odamaki
      • K. Namba
      • F. Abe
      • J. Xiao

    • PubMed: 26420070
    • DOI: 10.3920/BM2015.0035

    2 Insights on

    • Reduced Pathological Symptoms
    • Reduced Inflammatory Molecules

    • Low evidence
    • Animal Study
• February 3

  • Probiotics and Alcoholic Liver Disease: Treatment and Potential Mechanisms.

    • 2016-02-03
    • Review
    • Gastroenterology research and practice 2016
    • • Fengyuan Li
      • Kangmin Duan
      • Cuiling Wang
      • Craig McClain
      • Wenke Feng

    • PubMed: 26839540
    • DOI: 10.1155/2016/5491465

    2 Insights on

    • Reduced Disease Severity
    • Improvement in Alcoholic Liver Disease

    • Low evidence
• February 5

  • Lactobacillus casei Exerts Anti-Proliferative Effects Accompanied by Apoptotic Cell Death and Up-Regulation of TRAIL in Colon Carcinoma Cells

    • 2016-02-05
    • Clinical Trial
    • PLOS ONE 11(2)
    • • A. Tiptiri-Kourpeti
      • K. Spyridopoulou
      • Valentina Santarmaki
      • Georgios Aindelis
      • Evgenia Tompoulidou
      • E. Lamprianidou
      • G. Saxami
      • P. Ypsilantis
      • E. Lampri
      • C. Simopoulos
      • I. Kotsianidis
      • A. Galanis
      • Y. Kourkoutas
      • D. Dimitrellou
      • K. Chlichlia

    • PubMed: 26849051
    • DOI: 10.1371/journal.pone.0147960

    3 Insights on

    • Reduced Tumor Volume
    • Reduced Tumor Growth
    • Reduced Cell Viability

    • Low evidence
    • Highly Cited
    • Rigorous Journal
    • Animal Study
• February 15

  • Lactobacillus rhamnosus GR-1 Ameliorates Escherichia coli-Induced Inflammation and Cell Damage via Attenuation of ASC-Independent NLRP3 Inflammasome Activation

    • 2016-02-15
    • Applied and Environmental Microbiology 82(4)
    • • Qiong Wu
      • Mingchao Liu
      • Jun Yang
      • Jiufeng Wang
      • Yaohong Zhu

    • PubMed: 26655757
    • DOI: 10.1128/AEM.03044-15

    3 Insights on

    • Reduced Inflammation Levels
    • Reduced Cellular Damage
    • Reduced E. coli Pathogenic Effects

    • Low evidence
• February 16

  • Gut epithelial inducible heat-shock proteins and their modulation by diet and the microbiota.

    • 2016-02-16
    • Review
    • Nutrition reviews 74(3)
    • • Marie-Edith Arnal
      • Jean-Paul Lallès

    • PubMed: 26883882
    • DOI: 10.1093/nutrit/nuv104

    1 Insight on

    • Improved Intestinal Barrier Function

    • Low evidence
• February 24

  • Probiotic Yogurt Culture Bifidobacterium Animalis Subsp. Lactis BB-12 and Lactobacillus Acidophilus LA-5 Modulate the Cytokine Secretion by Peripheral Blood Mononuclear Cells from Patients with Ulcerative Colitis.

    • 2016-02-24
    • Drug research 66(06)
    • • A Sheikhi
      • M Shakerian
      • H Giti
      • M Baghaeifar
      • A Jafarzadeh
      • V Ghaed
      • M R Heibor
      • N Baharifar
      • Z Dadafarin
      • G Bashirpour

    • PubMed: 26909690
    • DOI: 10.1055/s-0035-1569414

    1 Insight on

    • Increased Cytokine Secretion

    • Low evidence
• February 26

  • Effect of Bifidobacterium breve M-16V supplementation on faecal bifidobacteria in growth restricted very preterm infants – analysis from a randomised trial

    • 2016-02-26
    • RCT · n = 34
    • The Journal of Maternal-Fetal & Neonatal Medicine 29(23)
    • • S. Patole
      • A. Keil
      • E. Nathan
      • D. Doherty
      • Meera Esvaran
      • K. Simmer
      • P. Conway

    • PubMed: 26821074
    • DOI: 10.3109/14767058.2016.1147554

    4 Insights on

    • Increased Fecal Bifidobacteria Levels
    • Reduced Time to Reach Full Feeds
    • Earlier Achievement of Full Feeding
    • Increased Speed to Full Feeding

    • High evidence
• February 29

  • Evaluation of genetic and phenotypic consistency of Bacillus coagulans MTCC 5856: a commercial probiotic strain

    • 2016-02-29
    • World Journal of Microbiology and Biotechnology 32(4)
    • • M. Majeed
      • K. Nagabhushanam
      • Sankaran Natarajan
      • A. Sivakumar
      • Talitha Eshuis-de Ruiter
      • Janine Booij-Veurink
      • Y. P. de Vries
      • Furqan Ali

    • PubMed: 26925622
    • DOI: 10.1007/s11274-016-2027-2

    1 Insight on

    • Improved Safety Profile

    • Low evidence
• Undated – 7 supplement studies

  • Bifidobacterium breve BBG-001 in very preterm infants: a randomised controlled phase 3 trial

    • 2016-02
    • RCT · n = 1,315
    • The Lancet 387(10019)
    • • K. Costeloe
      • P. Hardy
      • E. Juszczak
      • M. Wilks
      • M. Millar

    • PubMed: 26628328
    • DOI: 10.1016/S0140-6736(15)01027-2

    12 Insights on

    • Reduced Severity of Necrotizing Enterocolitis
    • Increased Late-Onset Sepsis Incidence
    • Reduced Mortality Rate Before Discharge
    • Prevention of Necrotising Enterocolitis
    • Reduced Necrotising Enterocolitis
    • Reduced Mortality Rate
    • Reduced Incidence of Late-Onset Sepsis
    • Reduced Mortality Risk
    • Incidence of Necrotizing Enterocolitis
    • Reduced Incidence of Necrotizing Enterocolitis
    • Incidence of Late-Onset Sepsis
    • Increased Sepsis Incidence

    • High evidence
    • Large Human Trial
    • Highly Cited
    • Rigorous Journal

  • Effects of dietary supplementation of Lactobacillus rhamnosus or/and Lactococcus lactis on the growth, gut microbiota and immune responses of red sea bream, Pagrus major.

    • 2016-02
    • RCT
    • Fish & Shellfish Immunology 49
    • • M. Dawood
      • S. Koshio
      • M. Ishikawa
      • S. Yokoyama
      • M. F. El Basuini
      • Md. Sakhawat Hossain
      • Truong H. Nhu
      • Serge Dossou
      • Amina S. Moss

    • PubMed: 26766177
    • DOI: 10.1016/j.fsi.2015.12.047

    23 Insights on

    • Increased Lactic Acid Bacteria Levels
    • Increased Serum Lysozyme Activity
    • Improved Apparent Digestibility of Crude Protein
    • Improved Growth Performance
    • Increased Superoxide Dismutase Activity
    • Enhanced Immune Response
    • Improved Feed Utilization
    • Enhanced Growth Performance
    • Increased Superoxide Dismutase Levels
    • Increased Protease Activity
    • Increased Plasma Total Protein
    • Improved Alternative Complement Pathway Activity
    • Increased Peroxidase Levels
    • Increased Mucus Secretion
    • Increased Hematocrit Levels
    • Enhanced Antioxidant Capacity
    • Increased Gut Lactic Acid Bacteria Count
    • Increased Protein Digestibility
    • Increased Intestinal Lactic Acid Bacteria Count
    • Improved Plasma Total Protein
    • Increased Complement Pathway Activity
    • Increased Peroxidase Activity
    • Improved Fish Chemical Composition

    • High evidence
    • Highly Cited

  • Biofilms of Lactobacillus plantarum and Lactobacillus fermentum: Effect on stress responses, antagonistic effects on pathogen growth and immunomodulatory properties.

    • 2016-02
    • Food Microbiology 53
    • • N. Aoudia
      • A. Rieu
      • R. Briandet
      • J. Deschamps
      • J. Chluba
      • G. Jego
      • C. Garrido
      • J. Guzzo

    • PubMed: 26611169
    • DOI: 10.1016/j.fm.2015.04.009

    1 Insight on

    • Reduced TNF Production

    • Low evidence
    • Highly Cited

  • Toxicological assessment of nattokinase derived from Bacillus subtilis var. natto.

    • 2016-02
    • Clinical Trial
    • Food and Chemical Toxicology 88
    • • Bradley J. Lampe
      • J. Caroline English

    • PubMed: 26740078
    • DOI: 10.1016/j.fct.2015.12.025

    3 Insights on

    • Reduced Hypertension
    • Improved Anticoagulatory Effects
    • Reduced Toxicological Concern

    • Low evidence
    • Animal Study

  • Use of the dynamic gastro-intestinal model TIM to explore the survival of the yogurt bacterium Streptococcus thermophilus and the metabolic activities induced in the simulated human gut.

    • 2016-02
    • Food Microbiology 53
    • • O. Uriot
      • W. Galia
      • A. A. Awussi
      • C. Perrin
      • S. Denis
      • S. Chalancon
      • Emilie Lorson
      • C. Poirson
      • M. Junjua
      • Y. Le Roux
      • M. Alric
      • A. Dary
      • S. Blanquet-Diot
      • Y. Roussel

    • PubMed: 26611166
    • DOI: 10.1016/j.fm.2015.05.007

    2 Insights on

    • Improved Survival Rate
    • Improved Gastrointestinal Survival

    • Low evidence

  • Effectiveness of Lactobacillus reuteri DSM 17938 for the Prevention of Nosocomial Diarrhea in Children: A Randomized, Double-blind, Placebo-controlled Trial

    • 2016-02
    • RCT · n = 184
    • Pediatric Infectious Disease Journal 35(2)
    • • M. Urbańska
      • D. Gieruszczak-Bialek
      • H. Szymański
      • H. Szajewska

    • PubMed: 26551445
    • DOI: 10.1097/INF.0000000000000948

    2 Insights on

    • Reduced Nosocomial Diarrhea Incidence
    • Increased Adverse Effects

    • High evidence

  • Extraction, characterization and antioxidant activity of mycelial polysaccharides from Paecilomyces hepiali HN1.

    • 2016-02
    • Carbohydrate Polymers 137
    • • Zhongwei Wu
      • Mingxia Zhang
      • Minhao Xie
      • Zhuqing Dai
      • Xiaoqing Wang
      • Bing Hu
      • Hong Ye
      • Xiaoxiong Zeng

    • PubMed: 26686161
    • DOI: 10.1016/j.carbpol.2015.11.010

    1 Insight on

    • Reduced Hepatic Oxidative Stress

    • Low evidence