March 2014 Supplement Research Papers

• March 3

  • Effect of Bifidobacterium breve M-16V Supplementation on Fecal Bifidobacteria in Preterm Neonates - A Randomised Double Blind Placebo Controlled Trial

    • 2014-03-03
    • RCT · n = 159
    • PLoS ONE 9(3)
    • • S. Patole
      • A. Keil
      • An-Yi Chang
      • E. Nathan
      • D. Doherty
      • K. Simmer
      • Meera Esvaran
      • P. Conway

    • PubMed: 24594833
    • DOI: 10.1371/journal.pone.0089511

    10 Insights on

    • Increased Fecal Bifidobacteria Levels
    • Increased Fecal Bifidobacteria
    • Increased Fecal Bifidobacterium breve Levels
    • No Adverse Health Effects
    • Reduced Incidence of NEC Stage II or Greater
    • Reduced NEC Stage II Cases
    • Reduced Occurrence of NEC (Bell's Stage 2 or Higher)
    • Increased Fecal Bifidobacterium Count
    • Prevention of NEC Stage II
    • No Significant Increase in Adverse Effects

    • High evidence
    • Highly Cited
    • Rigorous Journal
• March 5

  • Lactobacillus brevis Strains from Fermented Aloe vera Survive Gastroduodenal Environment and Suppress Common Food Borne Enteropathogens

    • 2014-03-05
    • PLoS ONE 9(3)
    • • Young‐Wook Kim
      • Young-ju Jeong
      • Ah-Young Kim
      • H. Son
      • Jong-Am Lee
      • Cheong-Hwan Jung
      • Chae-Hyun Kim
      • Jaeman Kim

    • PubMed: 24598940
    • DOI: 10.1371/journal.pone.0090866

    8 Insights on

    • Improved Survival in Gastroduodenal Environment
    • Reduced Enteropathogenic Burden
    • Increased Production of Beneficial Neurotransmitter GABA
    • Reduced Enteropathogen Activity
    • Reduced Pathogenic Bacteria Levels
    • Reduced Enteropathogen Growth
    • Colonization of the Intestine
    • Increased GABA Production

    • Low evidence
    • Rigorous Journal
• March 7

  • Lipid-Lowering Effects of Pediococcus acidilactici M76 Isolated from Korean Traditional Makgeolli in High Fat Diet-Induced Obese Mice

    • 2014-03-07
    • RCT
    • Nutrients 6(3)
    • • Yeon‐jeong Moon
      • S. Baik
      • Y. Cha

    • PubMed: 24609135
    • DOI: 10.3390/nu6031016

    5 Insights on

    • Reduced Body Weight
    • Improved Lipid Profile
    • Reduced Adipose Tissue Weight
    • Reduced Lipid Synthesis Enzyme Levels
    • Reduced Adipose Tissue

    • Low evidence
    • Animal Study
• March 10

  • Lactobacillus reuteri Influences Regrowth of Mutans Streptococci after Full-Mouth Disinfection: A Double-Blind, Randomised Controlled Trial

    • 2014-03-10
    • RCT · n = 62
    • Caries Research 47(4)
    • • N. R. Vestman
      • P. Hasslöf
      • M. Keller
      • Elisabeth Granström
      • S. Roos
      • Svante Twetman
      • C. Stecksén-blicks

    • PubMed: 23486236
    • DOI: 10.1159/000347233

    1 Insight on

    • Delayed Regrowth of Mutans Streptococci

    • High evidence
• March 17

  • The early administration of Lactobacillus reuteri DSM 17938 controls regurgitation episodes in full-term breastfed infants

    • 2014-03-17
    • RCT · n = 40
    • International Journal of Food Sciences and Nutrition 65(5)
    • • F. Garofoli
      • E. Civardi
      • F. Indrio
      • I. Mazzucchelli
      • Micol Angelini
      • C. Tinelli
      • M. Stronati

    • PubMed: 24635827
    • DOI: 10.3109/09637486.2014.898251

    3 Insights on

    • Reduced Vomiting Frequency
    • Reduced Enteritis
    • Reduced Regurgitation Episodes

    • High evidence
• March 18

  • Impact of orally administered lozenges with Lactobacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis BB-12 on the number of salivary mutans streptococci, amount of plaque, gingival inflammation and the oral microbiome in healthy adults.

    • 2014-03-18
    • RCT · n = 31
    • Clinical oral investigations 19(1)
    • • Aino Toiviainen
      • Heli Jalasvuori
      • Emilia Lahti
      • Ulvi Gursoy
      • Seppo Salminen
      • Margherita Fontana
      • Susan Flannagan
      • George Eckert
      • Alexis Kokaras
      • Bruce Paster
      • Eva Söderling

    • PubMed: 24638207
    • DOI: 10.1007/s00784-014-1221-6

    2 Insights on

    • Reduced Plaque Accumulation
    • Reduced Gingival Inflammation

    • High evidence

  • Administration of Lactobacillus salivarius LI01 or Pediococcus pentosaceus LI05 improves acute liver injury induced by d-galactosamine in rats

    • 2014-03-18
    • Clinical Trial
    • Applied Microbiology and Biotechnology 98(12)
    • • L. Lv
      • Xin-Jun Hu
      • Guiyun Qian
      • Hua Zhang
      • H. Lu
      • Bei-wen Zheng
      • Li Jiang
      • Lan-Juan Li

    • PubMed: 24639205
    • DOI: 10.1007/s00253-014-5638-2

    8 Insights on

    • Increased Anti-Inflammatory Cytokine Levels
    • Increased Interleukin-10 Levels
    • Reduced Liver Enzyme Levels
    • Reduced Bacterial Translocation
    • Reduced Elevated Liver Enzymes
    • Prevented Increase in Total Bilirubin
    • Aggravated Liver Injury
    • Stabilized Total Bilirubin Levels

    • Low evidence
    • Animal Study
• March 24

  • Xylo-oligosaccharides alone or in synbiotic combination with Bifidobacterium animalis subsp. lactis induce bifidogenesis and modulate markers of immune function in healthy adults: a double-blind, placebo-controlled, randomised, factorial cross-over study

    • 2014-03-24
    • RCT
    • British Journal of Nutrition 111(11)
    • • C. Childs
      • H. Röytiö
      • E. Alhoniemi
      • Á. Fekete
      • S. Forssten
      • Natasa Hudjec
      • Ying Ni Lim
      • Cara J Steger
      • P. Yaqoob
      • K. Tuohy
      • R. Rastall
      • A. Ouwehand
      • G. Gibson

    • PubMed: 24661576
    • DOI: 10.1017/S0007114513004261

    5 Insights on

    • Reduced Interleukin-4 Levels
    • Reduced Proinflammatory Cytokine Secretion
    • Increased Faecal Bifidobacterium Lactis Content
    • Reduced Salivary IgA Levels
    • Elevated IL-6 Levels

    • High evidence
    • Highly Cited
• March 28

  • The Science behind the Probiotic Strain Bifidobacterium animalis subsp. lactis BB-12®

    • 2014-03-28
    • Review
    • Microorganisms 2(2)
    • • Mikkel Jungersen
      • A. Wind
      • E. Johansen
      • J. Christensen
      • Birgitte Stuer-Lauridsen
      • D. Eskesen

    • PubMed: 27682233
    • DOI: 10.3390/microorganisms2020092

    15 Insights on

    • Reduced Antibiotic-Associated Diarrhea
    • Improved Gastrointestinal Health
    • Reduced Diarrhea Incidence
    • Improved Immune Function
    • Improved Bowel Function
    • Maintained Intestinal Microbiota Stability
    • Reduced Respiratory Tract Infections
    • Improved Respiratory Infection Resistance
    • Absence of Treatment-Related Side Effects
    • Reduced Respiratory Infections
    • Reduced Diarrhea
    • Enhanced Resistance to Respiratory Infections
    • Reduced Side Effects from Antibiotic Treatment
    • Increased Resistance to Respiratory Infection
    • Reduced Acute Respiratory Tract Infection Incidence

    • High evidence
    • Highly Cited
    • Rigorous Journal

  • Protective effects of probiotic Lactobacillus rhamnosus IMC501 in mice treated with PhIP.

    • 2014-03-28
    • Clinical Trial
    • Journal of Microbiology and Biotechnology 24(3)
    • • L. Dominici
      • M. Villarini
      • F. Trotta
      • E. Federici
      • G. Cenci
      • M. Moretti

    • PubMed: 24346468
    • DOI: 10.4014/JMB.1309.09072

    3 Insights on

    • Reduced DNA Damage
    • Reduced Beta-Glucuronidase Activity
    • Reduced N-acetyl-β-glucosaminidase Activity

    • Low evidence
    • Animal Study
• March 30

  • Probiotic Attributes of Autochthonous Lactobacillus rhamnosus Strains of Human Origin

    • 2014-03-30
    • Applied Biochemistry and Biotechnology 173(1)
    • • Sheetal P. Pithva
      • Satyamitra L. Shekh
      • J. Dave
      • B. Vyas

    • PubMed: 24682879
    • DOI: 10.1007/s12010-014-0839-9

    1 Insight on

    • Enhanced Antimicrobial Resistance

    • Low evidence
• Undated – 3 supplement studies

  • Accumulation of polyphosphate in Lactobacillus spp. and its involvement in stress resistance.

    • 2014-03
    • Applied and environmental microbiology 80(5)
    • • Cristina Alcántara
      • Amalia Blasco
      • Manuel Zúñiga
      • Vicente Monedero

    • PubMed: 24375133
    • DOI: 10.1128/aem.03997-13

    1 Insight on

    • Reduced Polyphosphate Accumulation

    • Low evidence
    • Rigorous Journal

  • Effect of Lactobacillus brevis ATCC 8287 as a feeding supplement on the performance and immune function of piglets.

    • 2014-03
    • RCT · n = 20
    • Veterinary Immunology and Immunopathology 158(1-2)
    • • Tanja Lähteinen
      • A. Lindholm
      • T. Rinttilä
      • S. Junnikkala
      • R. Kant
      • T. Pietilä
      • K. Levonen
      • I. von Ossowski
      • G. Solano-Aguilar
      • M. Jakava-Viljanen
      • A. Palva

    • PubMed: 24074625
    • DOI: 10.1016/j.vetimm.2013.09.002

    12 Insights on

    • Increased Presence of Bifidobacterium lactis
    • Improved Gastrointestinal Health
    • Increased Body Weight
    • Reduced Body Weight
    • Change in Body Weight
    • Increased Immunoglobulin G Levels
    • No Change in Intestinal Mucosa Morphology
    • Improved Intestinal Immunomodulatory Function
    • Unchanged Intestinal Morphology
    • Altered Intestinal Mucosa Morphology
    • Gut Localization of Lactobacillus brevis
    • Increased L. brevis-specific IgG Concentrations

    • Low evidence
    • Animal Study

  • Efficacy and safety of Vitex agnus-castus extract for treatment of premenstrual syndrome in Japanese patients: a prospective, open-label study.

    • 2014-03
    • Clinical Trial
    • Advances in therapy 31(3)
    • • Mikio Momoeda
      • Hidetaka Sasaki
      • Eiko Tagashira
      • Masayuki Ogishima
      • Yuichi Takano
      • Kazunori Ochiai

    • PubMed: 24604699
    • DOI: 10.1007/s12325-014-0106-z

    15 Insights on

    • Reduced Flatulence
    • Reduced Fatigue
    • Reduced Pain Score
    • Reduced Irritability
    • Reduced Depressed Mood
    • Reduced Anger
    • Reduced Headache
    • Reduced Breast Fullness
    • Reduced Skin Disorder
    • Reduced Drowsiness
    • Reduced Sleeplessness
    • Reduced Premenstrual Syndrome Symptom Score
    • Improved Responder Rate
    • Improved Physician Global Assessment
    • Reduced Allergic Dermatitis

    • Moderate evidence