July 2015 Supplement Research Papers

• July 1

  • Effects of dietary supplementation with lysine-yielding Bacillus subtilis on gut morphology, cecal microflora, and intestinal immune response of Linwu ducks.

    • 2015-07-01
    • RCT
    • Journal of Animal Science 93(7)
    • • Y. Xing
      • S. Wang
      • J. Fan
      • A. Oso
      • S. W. Kim
      • D. Xiao
      • T. Yang
      • G. Liu
      • G. Jiang
      • Z. Li
      • L. Li
      • B. Zhang

    • PubMed: 26440014
    • DOI: 10.2527/jas.2014-8090

    7 Insights on

    • Reduced Pro-Inflammatory Cytokines
    • Increased Interferon-Gamma Levels
    • Improved Gut Morphology
    • Improved Gut Microflora
    • Reduced IL-10 Expression in Ileum
    • Improved Intestinal Immune Responsiveness
    • Reduced Pro-inflammatory Cytokine Expression in Ileum

    • High evidence
    • Rigorous Journal
• July 3

  • Vaginal colonisation by probiotic lactobacilli and clinical outcome in women conventionally treated for bacterial vaginosis and yeast infection

    • 2015-07-03
    • BMC Infectious Diseases 15(1)
    • • S. Pendharkar
      • E. Brandsborg
      • L. Hammarström
      • H. Marcotte
      • P. Larsson

    • PubMed: 26137971
    • DOI: 10.1186/s12879-015-0971-3

    5 Insights on

    • Reduced Recurrence of Bacterial Vaginosis
    • Increased Cure Rate of Bacterial Vaginosis
    • Reduced Risk of Bacterial Vaginosis
    • Sustained Remission of Bacterial Vaginosis
    • Sustained Relief from Recurrent Vulvovaginal Candidiasis

    • Moderate evidence
    • Highly Cited
    • Rigorous Journal
• July 10

  • Bifidobacterium pseudocatenulatum CECT 7765 Reduces Obesity-Associated Inflammation by Restoring the Lymphocyte-Macrophage Balance and Gut Microbiota Structure in High-Fat Diet-Fed Mice

    • 2015-07-10
    • RCT
    • PLOS ONE 10(7)
    • • Á. Moya-Pérez
      • Alexander Neef
      • Y. Sanz

    • PubMed: 26161548
    • DOI: 10.1371/journal.pone.0126976

    6 Insights on

    • Improved Insulin Sensitivity
    • Reduced Body Weight
    • Reduced Inflammation Levels
    • Improved Glucose Tolerance
    • Improved Lipid Profile
    • Improved Gut Microbiota Structure

    • Low evidence
    • Highly Cited
    • Rigorous Journal
    • Animal Study
• July 11

  • Survival and Metabolic Activity of Pediocin Producer Pediococcus acidilactici UL5: Its Impact on Intestinal Microbiota and Listeria monocytogenes in a Model of the Human Terminal Ileum

    • 2015-07-11
    • Microbial Ecology 72(4)
    • • B. Fernandez
      • P. Savard
      • I. Fliss

    • PubMed: 26162534
    • DOI: 10.1007/s00248-015-0645-0

    1 Insight on

    • Reduced Listeria Monocytogenes Population

    • Low evidence
    • Rigorous Journal
• July 17

  • Lactobacillus plantarum NCU116 improves liver function, oxidative stress and lipid metabolism in rats with high fat diet induced non-alcoholic fatty liver disease.

    • 2015-07-17
    • Food Funct. 5(12)
    • • Chuan Li
      • Shaoping Nie
      • K. Zhu
      • Q. Ding
      • Chang Li
      • T. Xiong
      • M. Xie

    • PubMed: 25317840
    • DOI: 10.1039/c4fo00549j

    7 Insights on

    • Reduced Hepatic Oxidative Stress
    • Reduced Endotoxin Levels
    • Improved Liver Function
    • Improved Lipid Metabolism
    • Reduced Hepatic Fat Accumulation
    • Reduced Pro-inflammatory Cytokine Levels
    • Regulated Colonic Bacterial Flora

    • Low evidence
    • Highly Cited
• July 23

  • Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota.

    • 2015-07-23
    • Allergology International 63(4)
    • • T. Enomoto
      • M. Sowa
      • Kei-ichi Nishimori
      • S. Shimazu
      • A. Yoshida
      • Kazuko Yamada
      • F. Furukawa
      • T. Nakagawa
      • N. Yanagisawa
      • N. Iwabuchi
      • T. Odamaki
      • F. Abe
      • J. Nakayama
      • J. Xiao

    • PubMed: 25056226
    • DOI: 10.2332/allergolint.13-OA-0683

    3 Insights on

    • Reduced Incidence of Atopic Dermatitis
    • No Adverse Effects
    • Reduced Proportion of Proteobacteria

    • Low evidence
    • Highly Cited
• July 24

  • Colonization, safety, and tolerability study of the Streptococcus salivarius 24SMBc nasal spray for its application in upper respiratory tract infections

    • 2015-07-24
    • Clinical Trial · n = 20
    • European Journal of Clinical Microbiology & Infectious Diseases 34(10)
    • • M. Santagati
      • M. Scillato
      • N. Muscaridola
      • V. Metoldo
      • I. Mantia
      • S. Stefani

    • PubMed: 26205666
    • DOI: 10.1007/s10096-015-2454-2

    4 Insights on

    • Improved Tolerability
    • Prevented Upper Respiratory Tract Infection
    • Persistent Nasal Colonization
    • Nasopharyngeal Colonization

    • High evidence
    • Rigorous Journal

  • Lactobacillus casei Low-Temperature, Dairy-Associated Proteome Promotes Persistence in the Mammalian Digestive Tract.

    • 2015-07-24
    • Journal of Proteome Research 14(8)
    • • Bokyung Lee
      • Sybille Tachon
      • R. Eigenheer
      • B. Phinney
      • M. Marco

    • PubMed: 26148687
    • DOI: 10.1021/acs.jproteome.5b00387

    2 Insights on

    • Increased Persistence of Probiotics in Fecal Matter
    • Improved Intestinal Survival

    • Low evidence
    • Rigorous Journal
• July 28

  • Bifidobacterium longum CCM 7952 Promotes Epithelial Barrier Function and Prevents Acute DSS-Induced Colitis in Strictly Strain-Specific Manner

    • 2015-07-28
    • Clinical Trial
    • PLOS ONE 10(7)
    • • D. Šrůtková
      • M. Schwarzer
      • T. Hudcovic
      • Z. Zákostelská
      • V. Dráb
      • A. Španová
      • B. Rittich
      • H. Kozakova
      • I. Schabussova

    • PubMed: 26218526
    • DOI: 10.1371/journal.pone.0134050

    6 Insights on

    • Improved Intestinal Barrier Function
    • Reduced Colitis-Related Mortality
    • Reduced Colitis Symptoms
    • Improved Epithelial Barrier Function
    • Prevention of Colitis
    • Reduced Clinical Symptoms of Colitis

    • Low evidence
    • Highly Cited
    • Rigorous Journal
    • Animal Study

  • Effects of Lactobacillus paracasei 01 fermented milk beverage on protection of intestinal epithelial cell in vitro.

    • 2015-07-28
    • Journal of the Science of Food and Agriculture 96(6)
    • • Yen-Po Chen
      • Chih‐An Hsu
      • W. Hung
      • Ming-Ju Chen

    • PubMed: 26147180
    • DOI: 10.1002/jsfa.7331

    4 Insights on

    • Enhanced Intestinal Epithelial Cell Growth
    • Reduced Intestinal Cell Death
    • Reduced Chemokine Production
    • Reduced Macromolecule Permeability

    • Low evidence
    • Rigorous Journal
• July 31

  • Exopolysaccharides Produced by Leuconostoc mesenteroides Strain NTM048 as an Immunostimulant To Enhance the Mucosal Barrier and Influence the Systemic Immune Response.

    • 2015-07-31
    • Journal of Agricultural and Food Chemistry 63(31)
    • • C. Matsuzaki
      • Asuka Hayakawa
      • Kenji Matsumoto
      • Toshihiko Katoh
      • Kenji Yamamoto
      • K. Hisa

    • PubMed: 26207929
    • DOI: 10.1021/acs.jafc.5b01960

    3 Insights on

    • Improved Intestinal Barrier Function
    • Enhanced Systemic Immune Response
    • Increased IgA Production

    • Low evidence
• Undated – 6 supplement studies

  • Interaction effects of dietary supplementation of heat-killed Lactobacillus plantarum and β-glucan on growth performance, digestibility and immune response of juvenile red sea bream, Pagrus major.

    • 2015-07
    • Clinical Trial
    • Fish & Shellfish Immunology 45(1)
    • • M. Dawood
      • S. Koshio
      • M. Ishikawa
      • S. Yokoyama

    • PubMed: 25661844
    • DOI: 10.1016/j.fsi.2015.01.033

    5 Insights on

    • Improved Immune Response
    • Improved Growth Performance
    • Improved Digestibility
    • Increased Serum Peroxidase Activity
    • Improved Oxidative Stress Resistance

    • Low evidence
    • Highly Cited
    • Animal Study

  • Role of probiotic Lactobacillus fermentum KKL1 in the preparation of a rice based fermented beverage.

    • 2015-07
    • Bioresource Technology 188
    • • Kuntal Ghosh
      • M. Ray
      • A. Adak
      • S. Halder
      • A. Das
      • A. Jana
      • Saswati Parua Mondal
      • C. Vágvölgyi
      • P. K. Das Mohapatra
      • B. Pati
      • K. C. Mondal

    • PubMed: 25693452
    • DOI: 10.1016/j.biortech.2015.01.130

    3 Insights on

    • Increased Antioxidant Activity
    • Improved Bioavailability
    • Improved Probiotic Suitability

    • Low evidence
    • Highly Cited

  • Bacillus coagulans GBI-30, 6086 Modulates Faecalibacterium prausnitzii in Older Men and Women.

    • 2015-07
    • RCT · n = 36
    • The Journal of Nutrition 145(7)
    • • Edna P Nyangale
      • S. Farmer
      • H. Cash
      • D. Keller
      • D. Chernoff
      • G. Gibson

    • PubMed: 25948780
    • DOI: 10.3945/jn.114.199802

    6 Insights on

    • Increased Production of Anti-inflammatory Cytokine IL-10
    • Increased Faecalibacterium prausnitzii Levels
    • Increased Bacillus Species
    • Increased IL-10 Production
    • Increased Bacillus Species Populations
    • Increased Faecalibacterium prausnitzii Population

    • High evidence

  • Bacillus amyloliquefaciens supplementation alleviates immunological stress in lipopolysaccharide-challenged broilers at early age.

    • 2015-07
    • RCT
    • Poultry Science 94(7)
    • • Yanjiao Li
      • Huping Zhang
      • Y. Chen
      • M. Yang
      • L. Zhang
      • Zhuang Lu
      • Y. Zhou
      • T. Wang

    • PubMed: 26009750
    • DOI: 10.3382/ps/pev124

    3 Insights on

    • Increased Serum Lysozyme Activity
    • Improved Growth Performance
    • Reduced Total White Blood Cell Counts

    • High evidence
    • Rigorous Journal

  • Lactobacillus reuteri DSM 17938 shortens acute infectious diarrhea in a pediatric outpatient setting.

    • 2015-07
    • RCT · n = 64
    • Jornal de Pediatria 91(4)
    • • E. Dinleyici
      • N. Dalgıç
      • S. Guven
      • Ozge Metin
      • O. Yasa
      • Z. Kurugol
      • O. Turel
      • G. Tanır
      • A. Yazar
      • V. Arıca
      • M. Sancar
      • A. Karbuz
      • M. Eren
      • M. Ozen
      • A. Kara
      • Y. Vandenplas

    • PubMed: 25986615
    • DOI: 10.1016/j.jped.2014.10.009

    4 Insights on

    • Reduced Duration of Diarrhea
    • Reduced Diarrhea Incidence
    • Reduced Diarrhea Rate
    • No Adverse Health Effects

    • High evidence

  • Encapsulated Lactococcus lactis with enhanced gastrointestinal survival for the development of folate enriched functional foods.

    • 2015-07
    • Bioresource Technology 188
    • • J. Divya
      • K. Nampoothiri

    • PubMed: 25686721
    • DOI: 10.1016/j.biortech.2015.01.073

    2 Insights on

    • Improved Gastrointestinal Survival
    • Increased Folate Levels

    • Low evidence