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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Dietary Administration of Bacillus subtilis Enhances Growth Performance, Immune Response and Disease Resistance in Cherry Valley Ducks
- 2016-12-08
- Clinical Trial
- Frontiers in Microbiology 7
- - Mengjiao Guo
  - Guangen Hao
  - Baohua Wang
  - Ning Li
  - Rong Li
  - Liangmeng Wei
  - T. Chai
- PubMed: 28008328
- DOI: 10.3389/fmicb.2016.01975
3 Insights on
- Low evidence
- Animal Study
Oral administration of Saccharomyces boulardii alters duodenal morphology, enzymatic activity and cytokine production response in broiler chickens.
- 2016-12-07
- RCT · n = 200
- Animal Science Journal 88(8)
- - Yajing Sun
  - I. R. Rajput
  - M. A. Arain
  - Yanfei Li
  - D. M. Baloch
- PubMed: 27925366
- DOI: 10.1111/asj.12757
5 Insights on
- Low evidence
- Animal Study
A Topical Gel From Flax Seed Oil Compared With Hand Splint in Carpal Tunnel Syndrome: A Randomized Clinical Trial.
- 2016-12-01
- RCT
- Journal of evidence-based complementary & alternative medicine 22(3)
- - Mohammad Setayesh
  - Amir Reza Sadeghifar
  - Nozar Nakhaee
  - Mohammad Kamalinejad
  - Hossein Rezaeizadeh
- PubMed: 27909031
- DOI: 10.1177/2156587216677822
2 Insights on
- Improved Carpal Tunnel Syndrome
- Improved Hand Function
- High evidence
Precision medicine in alcoholic and nonalcoholic fatty liver disease via modulating the gut microbiota.
- 2016-12-01
- Review
- American journal of physiology. Gastrointestinal and liver physiology 311(6)
- - Sena Bluemel
  - Brandon Williams
  - Rob Knight
  - Bernd Schnabl
- PubMed: 27686615
- DOI: 10.1152/ajpgi.00245.2016
4 Insights on
- Low evidence
Lactobacillus delbrueckii subsp lactis CIDCA 133 modulates response of human epithelial and dendritic cells infected with Bacillus cereus.
- 2016-11-30
- Beneficial Microbes 7(5)
- - I. Rolny
  - I. Tiscornia
  - S. Racedo
  - P. Perez
  - M. Bollati-Fogolín
- PubMed: 27459335
- DOI: 10.3920/BM2015.0191
3 Insights on
- Low evidence
The lectin-like protein 1 in Lactobacillus rhamnosus GR-1 mediates tissue-specific adherence to vaginal epithelium and inhibits urogenital pathogens
- 2016-11-21
- Scientific Reports 6(1)
- - M. Petrova
  - Elke Lievens
  - T. Verhoeven
  - Jean M. Macklaim
  - G. Gloor
  - D. Schols
  - J. Vanderleyden
  - G. Reid
  - S. Lebeer
- PubMed: 27869151
- DOI: 10.1038/srep37437
1 Insight on
- Improved Vaginal Epithelial Cell Adherence
- Low evidence
Safety of Bifidobacterium breve (BBG‐01) in preterm infants
- 2016-11-17
- Pediatrics International 59(3)
- - H. Kitajima
  - Shinya Hirano
- PubMed: 27538261
- DOI: 10.1111/ped.13123
3 Insights on
- Low evidence
- Rigorous Journal
Lactobacillus plantarum HAC01 regulates gut microbiota and adipose tissue accumulation in a diet-induced obesity murine model
- 2016-11-17
- RCT
- Applied Microbiology and Biotechnology 101(4)
- - Soyoung Park
  - Yosep Ji
  - Hoe-Yune Jung
  - Hyunjoon Park
  - Jihee Kang
  - Sanghaeng Choi
  - Heuynkil Shin
  - C. Hyun
  - Kyong-Tai Kim
  - W. Holzapfel
- PubMed: 27858139
- DOI: 10.1007/s00253-016-7953-2
1 Insight on
- Reduced Mesenteric Adipose Tissue Accumulation
- Low evidence
- Highly Cited
- Animal Study
Preclinical Immunomodulation by the Probiotic Bifidobacterium breve M-16V in Early Life
- 2016-11-07
- Clinical Trial
- PLOS ONE 11(11)
- - M. Rigo-Adrover
  - À. Franch
  - M. Castell
  - F. Pérez-Cano
- PubMed: 27820846
- DOI: 10.1371/journal.pone.0166082
2 Insights on
- Increased Fecal Immunoglobulin A Levels
- Improved Mucosal Immunity
- Low evidence
- Rigorous Journal
- Animal Study
Effect of Potential Probiotic Lactococcus lactis Subsp. lactis on Growth Performance, Intestinal Microbiota, Digestive Enzyme Activities, and Disease Resistance of Litopenaeus vannamei
- 2016-11-07
- Clinical Trial
- Probiotics and Antimicrobial Proteins 9(2)
- - M. Adel
  - A. El‐Sayed
  - S. Yeganeh
  - Maryam Dadar
  - S. Giri
- PubMed: 27822707
- DOI: 10.1007/s12602-016-9235-9
5 Insights on
- Low evidence
- Highly Cited
- Animal Study
Effects of oral intake of heat-killed Lactobacillus brevis SBC8803 (SBL88™) on dry skin conditions: A randomized, double-blind, placebo-controlled study
- 2016-11-02
- RCT · n = 126
- Experimental and Therapeutic Medicine 12(6)
- - M. Ogawa
  - A. Saiki
  - Y. Matsui
  - Norihiko Tsuchimoto
  - Y. Nakakita
  - Y. Takata
  - Takeshi Nakamura
- PubMed: 28105118
- DOI: 10.3892/etm.2016.3862
4 Insights on
- High evidence
- Rigorous Journal
Magnesium in obstetric anesthesia and intensive care.
- 2016-11-01
- Review
- Journal of anesthesia 31(1)
- - Marija S Kutlesic
  - Ranko M Kutlesic
  - Tatjana Mostic-Ilic
- PubMed: 27803982
- DOI: 10.1007/s00540-016-2257-3
6 Insights on
- Low evidence
Heat-Killed Lactobacillus salivarius and Lactobacillus johnsonii Reduce Liver Injury Induced by Alcohol In Vitro and In Vivo
- 2016-10-31
- Molecules 21(11)
- - C. Chuang
  - Cheng-Chih Tsai
  - E. Lin
  - Chin-Shiu Huang
  - Yun-Yu Lin
  - Chuan-Ching Lan
  - Chun-Chih Huang
- PubMed: 27809254
- DOI: 10.3390/MOLECULES21111456
3 Insights on
- Low evidence
The use of probiotic L. fermentum ME-3 containing Reg'Activ Cholesterol supplement for 4 weeks has a positive influence on blood lipoprotein profiles and inflammatory cytokines: an open-label preliminary study.
- 2016-10-28
- Clinical Trial
- Nutrition journal 15(1)
- - Tiiu Kullisaar
  - Kersti Zilmer
  - Tiit Salum
  - Aune Rehema
  - Mihkel Zilmer
- PubMed: 27793203
- DOI: 10.1186/s12937-016-0213-6
4 Insights on
- Moderate evidence
Functional Probiotic Characterization and In Vivo Cholesterol-Lowering Activity of Lactobacillus helveticus Isolated from Fermented Cow Milk.
- 2016-10-28
- Journal of Microbiology and Biotechnology 26(10)
- - Karthiyaini Damodharan
  - S. Palaniyandi
  - S. Yang
  - J. Suh
- PubMed: 27435541
- DOI: 10.4014/jmb.1603.03005
2 Insights on
- Reduced Low-Density Lipoprotein Level
- Reduced Serum Total Cholesterol Levels
- Low evidence
Lactobacillus fermentum ATCC 23271 Displays In vitro Inhibitory Activities against Candida spp.
- 2016-10-27
- Frontiers in Microbiology 7
- - Monique S do Carmo
  - Francisca M. F. Noronha
  - M. O. Arruda
  - E. P. Costa
  - M. Bomfim
  - A. Monteiro
  - T. Ferro
  - E. Fernandes
  - J. Girón
  - V. Monteiro-Neto
- PubMed: 27833605
- DOI: 10.3389/fmicb.2016.01722
2 Insights on
- Inhibited Growth of Candida Species
- Reduced Candida albicans Binding to Mucin
- Low evidence
Effect of Bifidobacterium breve on the Intestinal Microbiota of Coeliac Children on a Gluten Free Diet: A Pilot Study
- 2016-10-22
- RCT · n = 56
- Nutrients 8(10)
- - Andrea Quagliariello
  - I. Aloisio
  - Nicole Bozzi Cionci
  - D. Luiselli
  - G. D’Auria
  - L. Martinez-Priego
  - David Pérez-Villarroya
  - T. Langerholc
  - Maša Primec
  - D. Mičetić-Turk
  - D. Di Gioia
- PubMed: 27782071
- DOI: 10.3390/NU8100660
4 Insights on
- High evidence
- Highly Cited
Probiotic Properties of Lactobacillus plantarum RYPR1 from an Indigenous Fermented Beverage Raabadi
- 2016-10-21
- Frontiers in Microbiology 7
- - R. Yadav
  - A. K. Puniya
  - Pratyoosh Shukla
- PubMed: 27818658
- DOI: 10.3389/fmicb.2016.01683
7 Insights on
- Low evidence
- Highly Cited
Probiotic Streptococcus thermophilus FP4 and Bifidobacterium breve BR03 Supplementation Attenuates Performance and Range-of-Motion Decrements Following Muscle Damaging Exercise.
- 2016-10-14
- RCT
- Nutrients 8(10)
- - Ralf Jäger
  - Martin Purpura
  - Jason D Stone
  - Stephanie M Turner
  - Anthony J Anzalone
  - Micah J Eimerbrink
  - Marco Pane
  - Angela Amoruso
  - David S Rowlands
  - Jonathan M Oliver
- PubMed: 27754427
- DOI: 10.3390/nu8100642
6 Insights on
- High evidence
- Rigorous Journal
Systematic review and meta-analysis: the effects of fermented milk with Bifidobacterium lactis CNCM I-2494 and lactic acid bacteria on gastrointestinal discomfort in the general adult population
- 2016-10-10
- Meta-Analysis
- Therapeutic Advances in Gastroenterology 10(1)
- - J. Eales
  - P. Gibson
  - P. Whorwell
  - J. Kellow
  - A. Yellowlees
  - R. Perry
  - M. Edwards
  - Sarah King
  - H. Wood
  - Julie May Glanville
- PubMed: 28286561
- DOI: 10.1177/1756283X16670075
3 Insights on
- High evidence
- Rigorous Journal
Supplementation with Lactobacillus plantarum WCFS1 Prevents Decline of Mucus Barrier in Colon of Accelerated Aging Ercc1−/Δ7 Mice
- 2016-10-07
- Clinical Trial
- Frontiers in Immunology 7
- - A. V. Van Beek
  - B. Sovran
  - F. Hugenholtz
  - B. Meijer
  - J. Hoogerland
  - V. Mihailova
  - C. P. van der Ploeg
  - C. Belzer
  - M. Boekschoten
  - J. Hoeijmakers
  - W. Vermeij
  - P. de Vos
  - J. Wells
  - P. Leenen
  - C. Nicoletti
  - R. Hendriks
  - H. Savelkoul
- PubMed: 27774093
- DOI: 10.3389/fimmu.2016.00408
5 Insights on
- Low evidence
- Animal Study
Differential protection by cell wall components of Lactobacillus amylovorus DSM 16698Tagainst alterations of membrane barrier and NF-kB activation induced by enterotoxigenic F4+Escherichia coli on intestinal cells
- 2016-09-29
- BMC Microbiology 16(1)
- - Marianna Roselli
  - A. Finamore
  - U. Hynönen
  - A. Palva
  - E. Mengheri
- PubMed: 27688074
- DOI: 10.1186/s12866-016-0847-8
2 Insights on
- Enhanced Membrane Barrier Integrity
- Impaired Intestinal Barrier Function
- Low evidence
Investigation of Streptococcus salivarius-mediated inhibition of pneumococcal adherence to pharyngeal epithelial cells
- 2016-09-29
- BMC Microbiology 16(1)
- - Jayne Manning
  - Jayne Manning
  - E. Dunne
  - P. Wescombe
  - J. Hale
  - E. Mulholland
  - E. Mulholland
  - J. Tagg
  - R. Robins-Browne
  - R. Robins-Browne
  - C. Satzke
  - C. Satzke
- PubMed: 27681377
- DOI: 10.1186/s12866-016-0843-z
2 Insights on
- Reduced Pneumococcal Adherence
- Blocked Pneumococcal Binding Sites
- Low evidence
Genome Analysis and Characterisation of the Exopolysaccharide Produced by Bifidobacterium longum subsp. longum 35624™
- 2016-09-22
- PLOS ONE 11(9)
- - F. Altmann
  - P. Kosma
  - A. O’Callaghan
  - S. Leahy
  - F. Bottacini
  - Evelyn M. Molloy
  - S. Plattner
  - E. Schiavi
  - Marita Gleinser
  - D. Groeger
  - R. Grant
  - Noelia Rodriguez Perez
  - S. Healy
  - Elisabeth Svehla
  - Markus Windwarder
  - A. Hofinger
  - M. O'Connell Motherway
  - C. Akdis
  - Jun Xu
  - J. Roper
  - D. van Sinderen
  - L. O’Mahony
- PubMed: 27656878
- DOI: 10.1371/journal.pone.0162983
4 Insights on
- Moderate evidence
- Highly Cited
- Rigorous Journal
A multi-strain Synbiotic may reduce viral respiratory infections in asthmatic children: a randomized controlled trial.
- 2016-09-20
- RCT · n = 72
- Electronic physician 8(9)
- - Hamid Ahanchian
  - Seyed Ali Jafari
  - Elham Ansari
  - Toktam Ganji
  - Mohammad Ali Kiani
  - Maryam Khalesi
  - Tooba Momen
  - Hamidreza Kianifar
- PubMed: 27790333
- DOI: 10.19082/2833
2 Insights on
- Reduced Viral Respiratory Infection
- Reduced Asthma Medication Use
- High evidence
Health-promoting properties exhibited by Lactobacillus helveticus strains.
- 2016-09-19
- Acta Biochimica Polonica 62(4)
- - K. Skrzypczak
  - W. Gustaw
  - A. Waśko
- PubMed: 26601325
- DOI: 10.18388/abp.2015_1116
3 Insights on
- Low evidence
Review on Bifidobacterium bifidum BGN4: Functionality and Nutraceutical Applications as a Probiotic Microorganism
- 2016-09-14
- Review
- International Journal of Molecular Sciences 17(9)
- - Seockmo Ku
  - Myeong-Soo Park
  - G. Ji
  - H. You
- PubMed: 27649150
- DOI: 10.3390/ijms17091544
4 Insights on
- Moderate evidence
- Highly Cited
Investigating the Effect of Different Treatments with Lactic Acid Bacteria on the Fate of Listeria monocytogenes and Staphylococcus aureus Infection in Galleria mellonella Larvae.
- 2016-09-12
- PloS one 11(9)
- - Athena Grounta
  - Paschalis Harizanis
  - Eleftherios Mylonakis
  - George-John E Nychas
  - Efstathios Z Panagou
- PubMed: 27618619
- DOI: 10.1371/journal.pone.0161263
1 Insight on
- Reduced Pathogenic Load
- Low evidence
- Animal Study
Effect of dietary heat-killed Lactobacillus brevis SBC8803 (SBL88™) on sleep: a non-randomised, double blind, placebo-controlled, and crossover pilot study.
- 2016-09-01
- RCT · n = 17
- Beneficial Microbes 7(4)
- - Y. Nakakita
  - Norihiko Tsuchimoto
  - Y. Takata
  - Takeshi Nakamura
- PubMed: 27013460
- DOI: 10.3920/BM2015.0118
9 Insights on
- High evidence
Selected Lactobacillus strains isolated from sugary and milk kefir reduce Salmonella infection of epithelial cells in vitro.
- 2016-09-01
- Beneficial Microbes 7(4)
- - L. Zavala
  - M. Golowczyc
  - K. van Hoorde
  - M. Medrano
  - G. Huys
  - P. Vandamme
  - A. Abraham
- PubMed: 27291404
- DOI: 10.3920/BM2015.0196
2 Insights on
- Reduced Salmonella Enterica Invasion
- Reduced Cytoskeleton Disruption
- Low evidence