Skip to main content

Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Vaginal colonization by probiotic Lactobacillus crispatus CTV-05 is decreased by sexual activity and endogenous Lactobacilli.
- 2009-05-15
- RCT · n = 90
- The Journal of Infectious Diseases 199(10)
- - M. Antonio
  - L. Meyn
  - P. Murray
  - B. Busse
  - S. Hillier
- PubMed: 19331578
- DOI: 10.1086/598686
2 Insights on
- Reduced Vaginal Colonization by Probiotic Lactobacillus
- Increased Vaginal Colonization by Lactobacillus crispatus CTV-05
- High evidence
- Highly Cited
- Rigorous Journal
Effects of Lactobacillus plantarum MA2 isolated from Tibet kefir on lipid metabolism and intestinal microflora of rats fed on high-cholesterol diet
- 2009-05-15
- Clinical Trial
- Applied Microbiology and Biotechnology 84(2)
- - Yanping Wang
  - N. Xu
  - A. Xi
  - Zaheer Ahmed
  - Bin Zhang
  - Xiaojia Bai
- PubMed: 19444443
- DOI: 10.1007/s00253-009-2012-x
19 Insights on
- Low evidence
- Highly Cited
- Animal Study
Suppressive effects of bifidobacterium breve strain M-16V on T-helper type 2 immune responses in a murine model.
- 2009-05-12
- Clinical Trial
- Biological and Pharmaceutical Bulletin 32(4)
- - Y. Inoue
  - N. Iwabuchi
  - J. Xiao
  - T. Yaeshima
  - K. Iwatsuki
- PubMed: 19336921
- DOI: 10.1248/BPB.32.760
4 Insights on
- Low evidence
- Animal Study
Probiotic properties of Lactobacillus rhamnosus and Lactobacillus paracasei isolated from human faeces
- 2009-04-14
- European Journal of Nutrition 48(6)
- - M. Verdenelli
  - F. Ghelfi
  - S. Silvi
  - C. Orpianesi
  - C. Cecchini
  - A. Cresci
- PubMed: 19365593
- DOI: 10.1007/s00394-009-0021-2
6 Insights on
- Low evidence
- Highly Cited
Effect of a fermented milk containing Bifidobacterium lactis DN-173010 on Chinese constipated women.
- 2009-04-02
- RCT
- World Journal of Gastroenterology 14(40)
- - Yue-xin Yang
  - M. He
  - Gang Hu
  - Jie Wei
  - P. Pagès
  - Xiankui Yang
  - S. Bourdu-Naturel
- PubMed: 18985817
- DOI: 10.3748/WJG.14.6237
7 Insights on
- High evidence
- Highly Cited
Safety Assessment of Lactobacillus fermentum CECT5716, a probiotic strain isolated from human milk
- 2009-03-13
- RCT · n = 40
- Journal of Dairy Research 76(2)
- - F. Lara‐Villoslada
  - S. Sierra
  - M. Díaz-Ropero
  - J. M. Rodríguez
  - J. Xaus
  - M. Olivares
- PubMed: 19281631
- DOI: 10.1017/S0022029909004014
9 Insights on
- Low evidence
- Animal Study
Administration of Pediococcus acidilactici or Saccharomyces cerevisiae boulardii modulates development of porcine mucosal immunity and reduces intestinal bacterial translocation after Escherichia coli challenge.
- 2009-03-01
- RCT
- Journal of Animal Science 87(3)
- - M. Lessard
  - M. Dupuis
  - N. Gagnon
  - E. Nadeau
  - J. Matte
  - J. Goulet
  - J. Fairbrother
- PubMed: 19028865
- DOI: 10.2527/jas.2008-0919
6 Insights on
- High evidence
- Highly Cited
Bifidobacterium longum PL03, Lactobacillus rhamnosus KL53A, and Lactobacillus plantarum PL02 in the Prevention of Antibiotic-Associated Diarrhea in Children: A Randomized Controlled Pilot Trial
- 2009-02-23
- RCT · n = 78
- Digestion 78(1)
- - H. Szymański
  - M. Armańska
  - K. Kowalska-Duplaga
  - H. Szajewska
- PubMed: 18701826
- DOI: 10.1159/000151300
4 Insights on
- High evidence
Effect of Molecules Secreted by Lactobacillus acidophilus Strain La-5 on Escherichia coli O157:H7 Colonization
- 2009-02-15
- Clinical Trial
- Applied and Environmental Microbiology 75(4)
- - M. Medellin-Peña
  - M. Griffiths
- PubMed: 19088323
- DOI: 10.1128/AEM.01651-08
1 Insight on
- Reduced EHEC Colonization
- Low evidence
- Highly Cited
- Animal Study
Inhibiting effects of Streptococcus salivarius on competence-stimulating peptide-dependent biofilm formation by Streptococcus mutans.
- 2009-02-12
- Oral Microbiology and Immunology 24(2)
- - S. Tamura
  - Hideo Yonezawa
  - Mizuho Motegi
  - R. Nakao
  - S. Yoneda
  - Haruo Watanabe
  - Tsuneyoshi Yamazaki
  - H. Senpuku
- PubMed: 19239643
- DOI: 10.1111/j.1399-302X.2008.00489.x
1 Insight on
- Reduced Mutans Streptococcus Counts
- Low evidence
- Highly Cited
Phylogeny in aid of the present and novel microbial lineages: diversity in Bacillus.
- 2009-02-12
- n = 2,611
- PloS one 4(2)
- - Shalini Porwal
  - Sadhana Lal
  - Simrita Cheema
  - Vipin Chandra Kalia
- PubMed: 19212464
- DOI: 10.1371/journal.pone.0004438
3 Insights on
- High evidence
Prebiotics, probiotics, synbiotics in surgery—are they only trendy, truly effective or even dangerous?
- 2008-12-16
- Systematic Review
- Langenbeck's Archives of Surgery 394(3)
- - N. Rayes
  - D. Seehofer
  - P. Neuhaus
- PubMed: 19084991
- DOI: 10.1007/s00423-008-0445-9
2 Insights on
- Reduced Mortality Rate
- Reduced Bacterial Infection Rates
- High evidence
Enterococcus faecalis induces aneuploidy and tetraploidy in colonic epithelial cells through a bystander effect.
- 2008-12-01
- Cancer Research 68(23)
- - Xingmin Wang
  - Toby D. Allen
  - R. May
  - S. Lightfoot
  - C. Houchen
  - M. Huycke
- PubMed: 19047172
- DOI: 10.1158/0008-5472.CAN-08-1551
2 Insights on
- Increased Chromosomal Instability
- Occurrence of Aneuploidy
- Low evidence
- Highly Cited
Probiotics modulate the Bifidobacterium microbiota of elderly nursing home residents
- 2008-11-28
- RCT · n = 66
- AGE 31(1)
- - S. Lahtinen
  - L. Tammela
  - J. Korpela
  - Riikka Parhiala
  - H. Ahokoski
  - H. Mykkänen
  - S. Salminen
- PubMed: 19234769
- DOI: 10.1007/s11357-008-9081-0
2 Insights on
- Increased Bifidobacteria Levels
- Improved Diversity of Gut Microbiota
- High evidence
- Highly Cited
Identification of the transcriptional response of human intestinal mucosa to Lactobacillus plantarum WCFS1 in vivo
- 2008-09-25
- RCT
- BMC Genomics 9(1)
- - F. Troost
  - Peter van Baarlen
  - P. Lindsey
  - A. Kodde
  - W. D. de Vos
  - M. Kleerebezem
  - R. Brummer
- PubMed: 18681965
- DOI: 10.1186/1471-2164-9-374
1 Insight on
- Altered Lipid Metabolism
- High evidence
- Highly Cited
Eradication of Salmonella Typhimurium infection in a murine model of typhoid fever with the combination of probiotic Lactobacillus fermentum ME-3 and ofloxacin
- 2008-09-12
- Clinical Trial
- BMC Microbiology 8(1)
- - K. Truusalu
  - R. Mikelsaar
  - P. Naaber
  - Tõnis Karki
  - T. Kullisaar
  - M. Zilmer
  - M. Mikelsaar
- PubMed: 18680567
- DOI: 10.1186/1471-2180-8-132
3 Insights on
- Low evidence
- Animal Study
Improvement of periodontal condition by probiotics with Lactobacillus salivarius WB21: a randomized, double-blind, placebo-controlled study.
- 2008-09-12
- RCT · n = 66
- Journal of Clinical Periodontology 35(10)
- - H. Shimauchi
  - G. Mayanagi
  - S. Nakaya
  - Maiko Minamibuchi
  - Yasuhiro Ito
  - K. Yamaki
  - H. Hirata
- PubMed: 18727656
- DOI: 10.1111/j.1600-051X.2008.01306.x
8 Insights on
- High evidence
- Highly Cited
Effect of yacon (Smallanthus sonchifolius) on colonic transit time in healthy volunteers.
- 2008-09-10
- RCT
- Digestion 78(1)
- - M Geyer
  - I Manrique
  - L Degen
  - C Beglinger
- PubMed: 18781073
- DOI: 10.1159/000155214
3 Insights on
- High evidence
Safety assessment of dairy microorganisms: the Lactococcus genus.
- 2008-09-01
- International Journal of Food Microbiology 126(3)
- - E. Casalta
  - M. Montel
- PubMed: 17976847
- DOI: 10.1016/J.IJFOODMICRO.2007.08.013
2 Insights on
- Reduced Human Infections
- Reduced Incidence of Fish Diseases
- Low evidence
- Highly Cited
Low breast milk TGF‐β2 is induced by Lactobacillus reuteri supplementation and associates with reduced risk of sensitization during infancy
- 2008-08-18
- RCT · n = 109
- Pediatric Allergy and Immunology 19(6)
- - M. Böttcher
  - T. Abrahamsson
  - M. Fredriksson
  - Ted Jakobsson
  - B. Björkstén
- PubMed: 18221472
- DOI: 10.1111/j.1399-3038.2007.00687.x
3 Insights on
- High evidence
- Highly Cited
Functional characteristics of Lactobacillus spp. from traditional Maasai fermented milk products in Kenya.
- 2008-08-15
- International Journal of Food Microbiology 126(1-2)
- - J. Mathara
  - U. Schillinger
  - C. Guigas
  - C. Franz
  - P. M. Kutima
  - S. Mbugua
  - Heuynkil Shin
  - W. Holzapfel
- PubMed: 18539351
- DOI: 10.1016/j.ijfoodmicro.2008.04.027
5 Insights on
- Low evidence
- Highly Cited
Probiotic Leuconostoc mesenteroides ssp. cremoris and Streptococcus thermophilus induce IL-12 and IFN-gamma production.
- 2008-08-04
- World Journal of Gastroenterology 14(8)
- - R. Kekkonen
  - Elina Kajasto
  - M. Miettinen
  - V. Veckman
  - R. Korpela
  - I. Julkunen
- PubMed: 18300344
- DOI: 10.3748/WJG.14.1192
2 Insights on
- Increased Interleukin-12 Production
- Enhanced IFN-γ Production
- Low evidence
- Highly Cited
Infective endocarditis caused by lactobacillus.
- 2008-07-29
- Case Report
- Internal Medicine 47(12)
- - S. Yagi
  - M. Akaike
  - M. Fujimura
  - T. Ise
  - S. Yoshida
  - Yuka Sumitomo
  - Yasumasa Ikeda
  - T. Iwase
  - K. Aihara
  - H. Azuma
  - A. Kurushima
  - Y. Ichikawa
  - T. Kitagawa
  - Takehiko Kimura
  - T. Nishiuchi
  - Toshio Matsumoto
- PubMed: 18552468
- DOI: 10.2169/INTERNALMEDICINE.47.0744
1 Insight on
- Development of Infective Endocarditis
- Low evidence
Influence of a combination of Lactobacillus acidophilus NCFM and lactitol on healthy elderly: intestinal and immune parameters.
- 2008-07-18
- RCT
- British Journal of Nutrition 101(3)
- - A. Ouwehand
  - K. Tiihonen
  - M. Saarinen
  - H. Putaala
  - N. Rautonen
- PubMed: 18634707
- DOI: 10.1017/S0007114508003097
3 Insights on
- High evidence
- Highly Cited
Effect of inulin on the human gut microbiota: stimulation of Bifidobacterium adolescentis and Faecalibacterium prausnitzii
- 2008-07-01
- British Journal of Nutrition 101(4)
- - Carlett Ramírez-Farías
  - K. Slezak
  - Zoë Fuller
  - A. Duncan
  - G. Holtrop
  - P. Louis
- PubMed: 18590586
- DOI: 10.1017/S0007114508019880
2 Insights on
- Increased Faecalibacterium prausnitzii Levels
- Increased Bifidobacterium adolescentis Levels
- Low evidence
- Highly Cited
Oral administration of heat-killed Lactobacillus brevis SBC8803 ameliorates the development of dermatitis and inhibits immunoglobulin E production in atopic dermatitis model NC/Nga mice.
- 2008-06-19
- Clinical Trial · n = 20
- Biological and Pharmaceutical Bulletin 31(5)
- - S. Segawa
  - Atsushi Hayashi
  - Y. Nakakita
  - H. Kaneda
  - J. Watari
  - H. Yasui
- PubMed: 18451512
- DOI: 10.1248/BPB.31.884
3 Insights on
- Low evidence
- Animal Study
Preliminary investigations of the colonisation of upper respiratory tract tissues of infants using a paediatric formulation of the oral probiotic Streptococcus salivarius K12
- 2008-06-17
- Clinical Trial · n = 19
- European Journal of Clinical Microbiology & Infectious Diseases 27(12)
- - Dan Power
  - Jeremy P. Burton
  - C. Chilcott
  - Patrick J. D. Dawes
  - J. Tagg
- PubMed: 18560907
- DOI: 10.1007/s10096-008-0569-4
3 Insights on
- High evidence
- Highly Cited
Probiotic products in Canada with clinical evidence: what can gastroenterologists recommend?
- 2008-06-03
- Review
- Canadian journal of gastroenterology = Journal canadien de gastroenterologie 22(2)
- - G Reid
  - K Anukam
  - T Koyama
- PubMed: 18299736
- DOI: 10.1155/2008/843892
1 Insight on
- Improved Gastrointestinal Health
- Low evidence
Comparative Genome Analysis of Lactobacillus reuteri and Lactobacillus fermentum Reveal a Genomic Island for Reuterin and Cobalamin Production
- 2008-05-12
- DNA Research 15(3)
- - H. Morita
  - Hidehiro Toh
  - S. Fukuda
  - H. Horikawa
  - K. Oshima
  - Takehito Suzuki
  - M. Murakami
  - S. Hisamatsu
  - Y. Kato
  - T. Takizawa
  - H. Fukuoka
  - T. Yoshimura
  - K. Itoh
  - D. O'sullivan
  - L. Mckay
  - H. Ohno
  - J. Kikuchi
  - T. Masaoka
  - M. Hattori
- PubMed: 18487258
- DOI: 10.1093/dnares/dsn009
2 Insights on
- Reduced Pathogen Growth
- Increased Vitamin B12 Levels
- Low evidence
- Highly Cited
Evaluation of the preventative effects exerted by Lactobacillus fermentum in an experimental model of septic shock induced in mice
- 2008-04-29
- Clinical Trial
- British Journal of Nutrition 101(1)
- - B. Arribas
  - M. Rodríguez-Cabezas
  - M. Comalada
  - E. Bailón
  - D. Camuesco
  - M. Olivares
  - J. Xaus
  - A. Zarzuelo
  - J. Gálvez
- PubMed: 18445307
- DOI: 10.1017/S0007114508986876
4 Insights on
- Low evidence
- Animal Study