May 2017 Supplement Research Papers

• May 1

  • Effects of a Lactobacillus salivarius mixture on performance, intestinal health and serum lipids of broiler chickens

    • 2017-05-01
    • Clinical Trial
    • PLOS ONE 12(5)
    • • P. Shokryazdan
      • Mohammad Faseleh Jahromi
      • J. Liang
      • K. Ramasamy
      • C. C. Sieo
      • Y. Ho

    • PubMed: 28459856
    • DOI: 10.1371/journal.pone.0175959

    7 Insights on

    • Reduced Total Cholesterol Levels
    • Reduced Low-Density Lipoprotein Level
    • Reduced Triglyceride Levels
    • Improved Body Weight
    • Increased Bifidobacterial Population
    • Reduced Abundance of Harmful Bacteria
    • Improved Intestinal Histomorphology

    • Low evidence
    • Highly Cited
    • Rigorous Journal
    • Animal Study
• May 4

  • Effect of dietary supplementation with Lactobacillus acidophilus D2/CSL (CECT 4529) on caecum microbioma and productive performance in broiler chickens

    • 2017-05-04
    • PLOS ONE 12(5)
    • • A. De Cesare
      • F. Sirri
      • G. Manfreda
      • Paola Moniaci
      • A. Giardini
      • M. Zampiga
      • A. Meluzzi

    • PubMed: 28472118
    • DOI: 10.1371/journal.pone.0176309

    8 Insights on

    • Increased Body Weight
    • Improved Body Weight
    • Increased Beneficial Gut Microbiota
    • Improved Metabolic Function
    • Reduced Ruminococcus Abundance
    • Reduced Occurrence of Pasty Vent
    • Increased Abundance of Coprococcus eutactus
    • Increased β-glucosidase Levels

    • Moderate evidence
    • Highly Cited
    • Rigorous Journal
• May 8

  • Modulation of gut microbiota and increase in fecal water content in mice induced by administration of Lactobacillus kefiranofaciens DN1.

    • 2017-05-08
    • RCT · n = 16
    • Food & Function 8(2)
    • • Dana Jeong
      • Dong‐Hyeon Kim
      • Il‐Byeong Kang
      • Hyunsook Kim
      • K. Song
      • Hong-Seok Kim
      • K. Seo

    • PubMed: 28121325
    • DOI: 10.1039/c6fo01559j

    4 Insights on

    • Reduced Pathogen Infection
    • Increased Fecal Water Content
    • Improved Gut Microbiome Composition
    • Alleviated Constipation

    • Low evidence
    • Animal Study

  • L-carnosine as an adjuvant to fluvoxamine in treatment of obsessive compulsive disorder: A randomized double-blind study.

    • 2017-05-08
    • RCT
    • Human psychopharmacology 32(4)
    • • Somaye Arabzadeh
      • Maryam Shahhossenie
      • Bita Mesgarpour
      • Farzin Rezaei
      • Mohammad Reza Shalbafan
      • Zahra Ghiasi
      • Shahin Akhondzadeh

    • PubMed: 28485008
    • DOI: 10.1002/hup.2584

    1 Insight on

    • Reduced Obsessive-Compulsive Symptoms

    • High evidence
• May 17

  • Deleterious Metabolic Effects of High Fructose Intake: The Preventive Effect of Lactobacillus kefiri Administration

    • 2017-05-17
    • Clinical Trial
    • Nutrients 9(5)
    • • M. G. Zubiría
      • S. Gambaro
      • María Amanda Rey
      • P. Carasi
      • M. Serradell
      • A. Giovambattista

    • PubMed: 28513533
    • DOI: 10.3390/nu9050470

    7 Insights on

    • Prevention of Weight Gain
    • Reduced Adipocyte Hypertrophy
    • Reduced Plasma Triglycerides
    • Reduced Liver Triglyceride Content
    • Improved Leptin Secretion
    • Reduced Glucose Intolerance
    • Reduced Local Inflammation

    • Low evidence
    • Animal Study
• May 19

  • Bifidobacteria and Their Health-Promoting Effects.

    • 2017-05-19
    • Microbiology Spectrum 5(3)
    • • C. Hidalgo-Cantabrana
      • S. Delgado
      • L. Ruiz
      • P. Ruas-Madiedo
      • B. Sánchez
      • A. Margolles

    • PubMed: 28643627
    • DOI: 10.1128/microbiolspec.BAD-0010-2016

    2 Insights on

    • Improved Immune System Maturation
    • Increased Bifidobacterial Development

    • Low evidence
    • Highly Cited

  • The Genomic Basis of Lactobacilli as Health-Promoting Organisms.

    • 2017-05-19
    • Microbiology Spectrum 5(3)
    • • E. Salvetti
      • P. O’Toole

    • PubMed: 28643623
    • DOI: 10.1128/microbiolspec.BAD-0011-2016

    2 Insights on

    • Improved Overall Health
    • Increased Longevity

    • Low evidence

  • Study protocol: evaluation of the probiotic Lactobacillus Fermentum CECT5716 for the prevention of mastitis in breastfeeding women: a randomised controlled trial.

    • 2017-05-19
    • RCT · n = 600
    • BMC pregnancy and childbirth 17(1)
    • • Diana M Bond
      • Jonathan M Morris
      • Natasha Nassar

    • PubMed: 28525984
    • DOI: 10.1186/s12884-017-1330-8

    3 Insights on

    • Reduced Incidence of Infectious Mastitis
    • Reduced Antibiotic Use
    • Improved Breastfeeding Duration

    • High evidence
    • Large Human Trial
• May 23

  • Lactobacillus rhamnosus HN001 and Lactobacillus acidophilus La-14 Attenuate Gardnerella vaginalis-Infected Bacterial Vaginosis in Mice

    • 2017-05-23
    • Clinical Trial
    • Nutrients 9(6)
    • • Se-Eun Jang
      • Jin-Ju Jeong
      • Su-Young Choi
      • Hyun-Jee Kim
      • M. Han
      • Dong-Hyun Kim

    • PubMed: 28545241
    • DOI: 10.3390/nu9060531

    5 Insights on

    • Reduced Inflammatory Response
    • Improved Symptoms of Bacterial Vaginosis
    • Enhanced Treg Cell Differentiation
    • Enhanced Immune Response Regulation
    • Reduced Bacterial Vaginosis Severity

    • Low evidence
    • Animal Study
• May 25

  • Prevent Effects of Lactobacillus Fermentum HY01 on Dextran Sulfate Sodium-Induced Colitis in Mice

    • 2017-05-25
    • Clinical Trial
    • Nutrients 9(6)
    • • Xiaoyong Chen
      • Xin Zhao
      • Hongwei Wang
      • Zelin Yang
      • Jian Li
      • Huayi Suo

    • PubMed: 28587089
    • DOI: 10.3390/nu9060545

    4 Insights on

    • Reduced Colonic Inflammation
    • Reduced Proinflammatory Factors
    • Reduced Inflammatory Pathways
    • Inhibited IκBα Degradation

    • Low evidence
    • Highly Cited
    • Animal Study
• May 30

  • Safety and tolerability of Bifidobacterium longum subspecies infantis EVC001 supplementation in healthy term breastfed infants: a phase I clinical trial

    • 2017-05-30
    • BMC Pediatrics 17(1)
    • • J. Smilowitz
      • Jackelyn Moya
      • Melissa A. Breck
      • Chelsea Cook
      • A. Fineberg
      • K. Angkustsiri
      • M. Underwood

    • PubMed: 28558732
    • DOI: 10.1186/s12887-017-0886-9

    13 Insights on

    • Improved Stool Consistency
    • Reduced Stool Frequency
    • Reduced Mean Number of Stools per Day
    • Increased Fecal Bifidobacteria Levels
    • Absence of Adverse Effects
    • Increased Adverse Events
    • No Significant Adverse Events
    • No Adverse Health Effects
    • Reduced Bowel Movements
    • Improved Stool Formation
    • Increased Bifidobacterium Levels
    • Improved Stool Quality
    • No Change in Adverse Events

    • Low evidence
    • Rigorous Journal

  • Bacillus coagulans GBI-30, 6086 increases plant protein digestion in a dynamic, computer-controlled in vitro model of the small intestine (TIM-1).

    • 2017-05-30
    • Beneficial Microbes 8(3)
    • • D. Keller
      • R. V. Dinter
      • H. Cash
      • S. Farmer
      • Koen Venema

    • PubMed: 28504581
    • DOI: 10.3920/BM2016.0196

    3 Insights on

    • Improved Colonic Health
    • Improved Protein Digestion
    • Improved Amino Acid Bioavailability

    • Low evidence

  • Exopolysaccharide-producing Streptococcus thermophilus CRL1190 reduces the inflammatory response caused by Helicobacter pylori.

    • 2017-05-30
    • Beneficial Microbes 8(3)
    • • G. Marcial
      • J. Villena
      • G. Faller
      • A. Hensel
      • G. F. de Valdez

    • PubMed: 28504579
    • DOI: 10.3920/BM2016.0186

    4 Insights on

    • Reduced Inflammatory Response
    • Reduced Inflammation Levels
    • Reduced Pathogen Adhesion
    • Improved Protection Against Helicobacter pylori

    • Low evidence

  • Lactobacillus rhamnosus CRL1505 nasal administration improves recovery of T-cell mediated immunity against pneumococcal infection in malnourished mice.

    • 2017-05-30
    • Clinical Trial
    • Beneficial Microbes 8(3)
    • • N. Barbieri
      • M. Herrera
      • S. Salva
      • J. Villena
      • S. Alvarez

    • PubMed: 28504568
    • DOI: 10.3920/BM2016.0152

    4 Insights on

    • Reduced Susceptibility to Pneumococcal Infection
    • Improved Resistance to Pneumococcal Respiratory Infection
    • Enhanced Cell-Mediated Immunity
    • Increased Th2 Cytokines Production

    • Low evidence
    • Animal Study
• May 31

  • Consumption of Dairy Yogurt Containing Lactobacillus paracasei ssp. paracasei, Bifidobacterium animalis ssp. lactis and Heat-Treated Lactobacillus plantarum Improves Immune Function Including Natural Killer Cell Activity

    • 2017-05-31
    • RCT · n = 200
    • Nutrients 9(6)
    • • Ayoung Lee
      • Young Ju Lee
      • H. J. Yoo
      • Minkyung Kim
      • Yeeun Chang
      • Dong Seog Lee
      • J. H. Lee

    • PubMed: 28561762
    • DOI: 10.3390/nu9060558

    14 Insights on

    • Improved Immune Function
    • Improved Natural Killer Cell Activity
    • Elevated Interleukin-12 Levels
    • Increased Interferon-Gamma Levels
    • Improved Immune Cell Function
    • Elevated IgG1 Levels
    • Enhanced Natural Killer Cell Activity
    • Increased Immunoglobulin G1 Levels
    • Elevated Serum IFN-γ Levels
    • Increased IFN-γ Concentration
    • Elevated Serum Immunoglobulin Levels
    • Increased Serum Interferon Gamma Levels
    • Increased IFN-γ Levels
    • Improved Natural Killer Cell Function

    • High evidence
    • Highly Cited
• Undated – 2 supplement studies

  • Effect of the dietary probiotic Clostridium butyricum on growth, intestine antioxidant capacity and resistance to high temperature stress in kuruma shrimp Marsupenaeus japonicus.

    • 2017-05
    • RCT
    • Journal of Thermal Biology 66
    • • Yafei Duan
      • Yue Zhang
      • Hong-biao Dong
      • Yun Wang
      • Jiasong Zhang

    • PubMed: 28477915
    • DOI: 10.1016/j.jtherbio.2017.04.004

    4 Insights on

    • Reduced Hepatic Oxidative Stress
    • Improved Intestinal Function
    • Improved Growth Performance
    • Enhanced Stress Resistance

    • High evidence

  • Effects of long‐term Bacillus subtilis CGMCC 1.921 supplementation on performance, egg quality, and fecal and cecal microbiota of laying hens

    • 2017-05
    • RCT
    • Poultry Science 96(5)
    • • J. R. Guo
      • X. Dong
      • S. Liu
      • J. Tong

    • PubMed: 27789747
    • DOI: 10.3382/ps/pew389

    4 Insights on

    • Increased Cecal Lactobacilli Levels
    • Increased Lactobacilli Levels
    • Reduced Escherichia coli Counts
    • Improved Eggshell Strength

    • High evidence
    • Rigorous Journal