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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Enriched selenium and its effects on growth and biochemical composition in Lactobacillus bulgaricus.
- 2007-02-17
- Journal of Agricultural and Food Chemistry 55(6)
- - S. Xia
  - Long Chen
  - Jun Liang
- PubMed: 17305360
- DOI: 10.1021/JF062946J
2 Insights on
- Enhanced Nutrient Composition
- Increased Selenium Absorption
- Low evidence
Lactobacillus reuteri (American Type Culture Collection Strain 55730) Versus Simethicone in the Treatment of Infantile Colic: A Prospective Randomized Study
- 2007-01-01
- RCT · n = 90
- Pediatrics 119(1)
- - F. Savino
  - E. Pelle
  - E. Palumeri
  - R. Oggero
  - R. Miniero
- PubMed: 17200238
- DOI: 10.1542/peds.2006-1222
5 Insights on
- High evidence
- Highly Cited
Ingestion of heat‐treated Lactobacillus rhamnosus GG prevents development of atopic dermatitis in NC/Nga mice
- 2006-12-20
- Clinical Trial
- Clinical & Experimental Allergy 37(2)
- - J. Sawada
  - H. Morita
  - A. Tanaka
  - Seppo Salminen
  - F. He
  - Hiroshi Matsuda
- PubMed: 17250703
- DOI: 10.1111/j.1365-2222.2006.02645.x
2 Insights on
- Relapse Prevention in Atopic Dermatitis
- Increased IL-10 Levels
- Low evidence
- Highly Cited
- Animal Study
Absence of efficacy of nonviable Lactobacillus acidophilus for the prevention of traveler's diarrhea: a randomized, double-blind, controlled study.
- 2006-11-01
- RCT · n = 348
- Clinical Infectious Diseases 43(9)
- - V. Briand
  - P. Buffet
  - S. Genty
  - K. Lacombe
  - N. Godineau
  - J. Salomon
  - Eric Vandemelbrouck
  - P. Ralaimazava
  - C. Goujon
  - S. Matheron
  - A. Fontanet
  - O. Bouchaud
- PubMed: 17029137
- DOI: 10.1086/508178
1 Insight on
- Reduced Diarrhea Rate
- High evidence
- Large Human Trial
- Rigorous Journal
Role of a probiotic (Saccharomyces boulardii) in management and prevention of diarrhoea.
- 2006-10-31
- RCT · n = 100
- World Journal of Gastroenterology 12(28)
- - AG Billoo
  - Ma Memon
  - S. Khaskheli
  - G. Murtaza
  - K. Iqbal
  - M. Shekhani
  - Ahson Siddiqi
- PubMed: 16874872
- DOI: 10.3748/WJG.V12.I28.4557
6 Insights on
- High evidence
- Highly Cited
Oral supplementation with Lactobacillus casei subspecies rhamnosus prevents enteric colonization by Candida species in preterm neonates: a randomized study.
- 2006-06-15
- RCT · n = 80
- Clinical Infectious Diseases 42(12)
- - P. Manzoni
  - M. Mostert
  - M. Leonessa
  - C. Priolo
  - D. Farina
  - C. Monetti
  - M. Latino
  - G. Gomirato
- PubMed: 16705580
- DOI: 10.1086/504324
4 Insights on
- High evidence
- Highly Cited
- Rigorous Journal
The F1F0-ATPase of Bifidobacterium animalis is involved in bile tolerance.
- 2006-06-08
- Environmental Microbiology 8(10)
- - B. Sánchez
  - C. G. de los Reyes-Gavilán
  - A. Margolles
- PubMed: 16958763
- DOI: 10.1111/J.1462-2920.2006.01067.X
1 Insight on
- Increased Bile Salt Tolerance
- Low evidence
- Highly Cited
Dose–response study of probiotic bacteria Bifidobacterium animalis subsp lactis BB-12 and Lactobacillus paracasei subsp paracasei CRL-341 in healthy young adults
- 2006-05-24
- RCT · n = 71
- European Journal of Clinical Nutrition 60(11)
- - C. Larsen
  - Susanne Dorthe Nielsen
  - P. Kæstel
  - Elke Brockmann
  - M. Bennedsen
  - Hanne Risager Christensen
  - D. Eskesen
  - B. Jacobsen
  - Kim F. Michaelsen
- PubMed: 16721394
- DOI: 10.1038/sj.ejcn.1602450
15 Insights on
- High evidence
- Highly Cited
Treatment of ADHD with French maritime pine bark extract, Pycnogenol.
- 2006-05-13
- RCT
- European child & adolescent psychiatry 15(6)
- - Jana Trebatická
  - Sona Kopasová
  - Zuzana Hradecná
  - Kamil Cinovský
  - Igor Skodácek
  - Ján Suba
  - Jana Muchová
  - Ingrid Zitnanová
  - Ingrid Zitnanová
  - Iweta Waczulíková
  - Peter Rohdewald
  - Zdenka Duracková
- PubMed: 16699814
- DOI: 10.1007/s00787-006-0538-3
3 Insights on
- High evidence
Selenium accumulation in prostate tissue during a randomized, controlled short-term trial of l-selenomethionine: a Southwest Oncology Group Study.
- 2006-04-01
- RCT · n = 34
- Clinical cancer research : an official journal of the American Association for Cancer Research 12(7)
- - Anita L Sabichi
  - J Jack Lee
  - Robert J Taylor
  - Ian M Thompson
  - Brian J Miles
  - Catherine M Tangen
  - Lori M Minasian
  - Louis L Pisters
  - John R Caton
  - Joseph W Basler
  - Seth P Lerner
  - David G Menter
  - James R Marshall
  - E David Crawford
  - Scott M Lippman
- PubMed: 16609032
- DOI: 10.1158/1078-0432.ccr-05-0937
3 Insights on
- High evidence
Inhibition of expression of a staphylococcal superantigen-like protein by a soluble factor from Lactobacillus reuteri.
- 2006-04-01
- Microbiology 152(4)
- - Jennifer M Laughton
  - E. Devillard
  - D. Heinrichs
  - G. Reid
  - J. McCormick
- PubMed: 16549678
- DOI: 10.1099/MIC.0.28654-0
1 Insight on
- Reduced Staphylococcus Aureus Virulence
- Low evidence
- Highly Cited
A comparison of effects of fish and beef protein on satiety in normal weight men.
- 2006-02-15
- RCT
- European journal of clinical nutrition 60(7)
- - S Borzoei
  - M Neovius
  - B Barkeling
  - A Teixeira-Pinto
  - S Rössner
- PubMed: 16482079
- DOI: 10.1038/sj.ejcn.1602397
4 Insights on
- High evidence
- Rigorous Journal
Saw palmetto for benign prostatic hyperplasia.
- 2006-02-09
- RCT · n = 225
- The New England journal of medicine 354(6)
- - Stephen Bent
  - Christopher Kane
  - Katsuto Shinohara
  - John Neuhaus
  - Esther S Hudes
  - Harley Goldberg
  - Andrew L Avins
- PubMed: 16467543
- DOI: 10.1056/nejmoa053085
6 Insights on
- High evidence
- Large Human Trial
- Highly Cited
Growth during the first 6 months of life in infants using formula enriched with Lactobacillus rhamnosus GG: double-blind, randomized trial.
- 2006-01-31
- RCT · n = 120
- Journal of Human Nutrition and Dietetics 19(1)
- - N. Vendt
  - H. Grunberg
  - T. Tuure
  - O. Malminiemi
  - E. Wuolijoki
  - V. Tillmann
  - E. Sepp
  - R. Korpela
- PubMed: 16448475
- DOI: 10.1111/J.1365-277X.2006.00660.X
6 Insights on
- High evidence
- Highly Cited
Invasive Saccharomyces infection: a comprehensive review.
- 2005-12-01
- Review
- Clinical Infectious Diseases 41(11)
- - A. Enache-Angoulvant
  - C. Hennequin
- PubMed: 16267727
- DOI: 10.1086/497832
2 Insights on
- Occurrence of Fungemia
- Invasive Saccharomyces Infection
- Moderate evidence
- Highly Cited
Oral administration of Bifidobacterium bifidum G9-1 suppresses total and antigen specific immunoglobulin E production in mice.
- 2005-11-30
- Clinical Trial
- Biological and Pharmaceutical Bulletin 28(8)
- - H. Ohno
  - Satoru Tsunemine
  - Y. Isa
  - M. Shimakawa
  - H. Yamamura
- PubMed: 16079493
- DOI: 10.1248/BPB.28.1462
2 Insights on
- Reduced Total IgE Levels
- Reduced Antigen-Specific IgE Levels
- Low evidence
- Animal Study
Cariogenicity of the Probiotic Bacterium Lactobacillus salivarius in Rats
- 2005-11-22
- Clinical Trial · n = 6
- Caries Research 39(6)
- - M. Matsumoto
  - M. Tsuji
  - H. Sasaki
  - K. Fujita
  - R. Nomura
  - K. Nakano
  - S. Shintani
  - T. Ooshima
- PubMed: 16251792
- DOI: 10.1159/000088183
4 Insights on
- Low evidence
- Animal Study
Immunostimulatory probiotic Lactobacillus rhamnosus HN001 and Bifidobacterium lactis HN019 do not induce pathological inflammation in mouse model of experimental autoimmune thyroiditis.
- 2005-08-15
- Clinical Trial
- International Journal of Food Microbiology 103(1)
- - J. S. Zhou
  - H. Gill
- PubMed: 16084270
- DOI: 10.1016/J.IJFOODMICRO.2004.11.031
2 Insights on
- Absence of Pathological Inflammation
- Unchanged Spleen Weight Index
- Low evidence
- Animal Study
Evaluation of the functional efficacy of an antioxidative probiotic in healthy volunteers
- 2005-08-04
- RCT
- Nutrition Journal 4(1)
- - E. Songisepp
  - J. Kals
  - T. Kullisaar
  - R. Mändar
  - P. Hütt
  - M. Zilmer
  - M. Mikelsaar
- PubMed: 16080791
- DOI: 10.1186/1475-2891-4-22
8 Insights on
- High evidence
- Highly Cited
- Rigorous Journal
Lactobacillus paracasei Strain ST11 Has No Effect on Rotavirus but Ameliorates the Outcome of Nonrotavirus Diarrhea in Children From Bangladesh
- 2005-08-01
- RCT · n = 230
- Pediatrics 116(2)
- - S. Sarker
  - S. Sultana
  - G. Fuchs
  - N. Alam
  - T. Azim
  - H. Brüssow
  - L. Hammarström
- PubMed: 15995003
- DOI: 10.1542/peds.2004-2334
9 Insights on
- High evidence
- Highly Cited
Saccharomyces cerevisiae fungemia: an emerging infectious disease.
- 2005-06-01
- Observational · n = 44
- Clinical Infectious Diseases 40(11)
- - P. Muñoz
  - E. Bouza
  - M. Cuenca‐Estrella
  - J. Eiros
  - M. Pérez
  - M. Sánchez-Somolinos
  - C. Rincón
  - J. Hortal
  - T. Peláez
- PubMed: 15889360
- DOI: 10.1086/429916
2 Insights on
- Reduced Mortality Risk
- Occurrence of Fungemia
- High evidence
- Highly Cited
Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence.
- 2005-04-15
- Review
- Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 1(2)
- - Amy Lynn Meolie
  - Carol Rosen
  - David Kristo
  - Michael Kohrman
  - Nalaka Gooneratne
  - Robert Neal Aguillard
  - Robert Fayle
  - Robert Troell
  - Don Townsend
  - David Claman
  - Timothy Hoban
  - Mark Mahowald
- PubMed: 17561634
- DOI: 10.5664/jcsm.26314
1 Insight on
- Improved Sleep Quality
- Low evidence
Effects of Long-Term Intervention with Lactobacillus helveticus-Fermented Milk on Bone Mineral Density and Bone Mineral Content in Growing Rats
- 2005-04-08
- RCT · n = 10
- Annals of Nutrition and Metabolism 48(4)
- - Mirkka Narva
  - M. Collin
  - C. Lamberg‐Allardt
  - M. Kärkkäinen
  - T. Poussa
  - H. Vapaatalo
  - R. Korpela
- PubMed: 15334032
- DOI: 10.1159/000080455
2 Insights on
- Improved Bone Mass Density
- Improved Bone Mineral Content
- Low evidence
- Animal Study
Microbiological effects of consuming a synbiotic containing Bifidobacterium bifidum, Bifidobacterium lactis, and oligofructose in elderly persons, determined by real-time polymerase chain reaction and counting of viable bacteria.
- 2005-01-01
- RCT · n = 18
- Clinical Infectious Diseases 40(1)
- - S. Bartosch
  - E. Woodmansey
  - J. C. Paterson
  - M. Mcmurdo
  - G. Macfarlane
- PubMed: 15614689
- DOI: 10.1086/426027
22 Insights on
- High evidence
- Highly Cited
The effect of Lactobacillus helveticus fermented milk on acute changes in calcium metabolism in postmenopausal women
- 2004-04-01
- RCT · n = 20
- European Journal of Nutrition 43(2)
- - Mirkka Narva
  - R. Nevala
  - T. Poussa
  - R. Korpela
- PubMed: 15083312
- DOI: 10.1007/S00394-004-0441-Y
6 Insights on
- High evidence
- Highly Cited
Cytokines evaluation in nasal lavage of allergic children after Bacillus clausii administration: A pilot study
- 2004-03-30
- Clinical Trial · n = 10
- Pediatric Allergy and Immunology 15(2)
- - G. Ciprandi
  - M. Tosca
  - M. Milanese
  - G. Caligo
  - V. Ricca
- PubMed: 15059191
- DOI: 10.1046/j.1399-3038.2003.00102.x
4 Insights on
- Moderate evidence
Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate anxiety disorders.
- 2003-10-20
- RCT · n = 264
- Current medical research and opinion 20(1)
- - Michel Hanus
  - Jacqueline Lafon
  - Marc Mathieu
- PubMed: 14741074
- DOI: 10.1185/030079903125002603
2 Insights on
- Reduced Anxiety
- Reduced Somatic Anxiety Symptom
- High evidence
- Large Human Trial
Effect of the proteolytic enzyme serrapeptase in patients with chronic airway disease.
- 2003-08-07
- RCT · n = 15
- Respirology (Carlton, Vic.) 8(3)
- - Seiichi Nakamura
  - Yasushi Hashimoto
  - Masashi Mikami
  - Eiichi Yamanaka
  - Tomoyuki Soma
  - Mitsunori Hino
  - Arata Azuma
  - Shoji Kudoh
- PubMed: 12911824
- DOI: 10.1046/j.1440-1843.2003.00482.x
8 Insights on
- High evidence
Evaluation of Bifidobacterium breve strain Yakult-fermented soymilk as a probiotic food.
- 2003-03-15
- International Journal of Food Microbiology 81(2)
- - Y. Shimakawa
  - S. Matsubara
  - N. Yuki
  - M. Ikeda
  - F. Ishikawa
- PubMed: 12457587
- DOI: 10.1016/S0168-1605(02)00224-6
14 Insights on
- Low evidence
- Highly Cited
Bifidobacterium adolescentis as a delivery system of endostatin for cancer gene therapy: Selective inhibitor of angiogenesis and hypoxic tumor growth
- 2003-01-21
- Clinical Trial
- Cancer Gene Therapy 10(2)
- - Xi Li
  - Gengfeng Fu
  - Yan-rong Fan
  - Wen-hua Liu
  - Xinju Liu
  - Jian-jun Wang
  - Gen-xing Xu
- PubMed: 12536198
- DOI: 10.1038/sj.cgt.7700530
3 Insights on
- Low evidence
- Highly Cited
- Animal Study