April 2015 Supplement Research Papers

• April 1

  • Effect of Long-Term Consumption of Lactobacillus paracasei SD1 on Reducing Mutans streptococci and Caries Risk: A Randomized Placebo-Controlled Trial

    • 2015-04-01
    • RCT · n = 122
    • Dentistry Journal 3(2)
    • • R. Teanpaisan
      • S. Piwat
      • S. Tianviwat
      • B. Sophatha
      • Thanyanan Kampoo

    • PubMed: 29567924
    • DOI: 10.3390/dj3020043

    9 Insights on

    • Reduced Salivary Levels of Mutans Streptococci
    • Reduced Dental Caries
    • Increased Lactobacilli Levels
    • Reduced Caries Lesions
    • Reduced Mutans Streptococcus Counts
    • Reduced Caries Risk
    • Reduced Streptococcus Mutans Levels
    • Reduced Mutans Streptococci Colonization
    • Reduced Caries Incidence

    • High evidence
    • Rigorous Journal

  • A lactose fermentation product produced by Lactococcus lactis subsp. lactis, acetate, inhibits the motility of flagellated pathogenic bacteria.

    • 2015-04-01
    • Microbiology 161(4)
    • • Shuichi Nakamura
      • Yusuke V. Morimoto
      • S. Kudo

    • PubMed: 25573770
    • DOI: 10.1099/mic.0.000031

    4 Insights on

    • Reduced Bacterial Motility
    • Reduced Pathogenic Bacterial Motility
    • Reduced Intracellular pH of Pathogenic Bacteria
    • Paralysis Due to Salmonella Infection

    • Low evidence

  • Effect of iron on the probiotic properties of the vaginal isolate Lactobacillus jensenii CECT 4306.

    • 2015-04-01
    • Microbiology 161(4)
    • • Rebeca Martín
      • B. Sánchez
      • M. Urdaci
      • P. Langella
      • J. Suárez
      • L. Bermúdez-Humarán

    • PubMed: 25635270
    • DOI: 10.1099/mic.0.000044

    1 Insight on

    • Increased Anti-Inflammatory Cytokine Levels

    • Low evidence
• April 3

  • Applications of Microencapsulated Bifidobacterium Longum with Eleutherine Americana in Fresh Milk Tofu and Pineapple Juice

    • 2015-04-03
    • Nutrients 7(4)
    • • A. Phoem
      • S. Chanthachum
      • S. Voravuthikunchai

    • PubMed: 25854832
    • DOI: 10.3390/nu7042469

    5 Insights on

    • Improved Bacterial Survival Rate
    • Improved Consumer Acceptance
    • Reduced Acidification in Pineapple Juice
    • Increased Bacterial Survival
    • Improved Consumer Acceptability

    • Moderate evidence
• April 6

  • Effects of Bifidobacterium supplementation on intestinal microbiota composition and the immune response in healthy infants

    • 2015-04-06
    • RCT · n = 300
    • World Journal of Pediatrics 12(2)
    • • Bingbing Wu
      • Yi Yang
      • Xiu Xu
      • Weiping Wang

    • PubMed: 25846071
    • DOI: 10.1007/s12519-015-0025-3

    2 Insights on

    • Improved Immune Response
    • Improved Intestinal Microbial Composition

    • High evidence
    • Large Human Trial
• April 16

  • Effects of Oral Administration of Lactobacillus acidophilus L-92 on the Symptoms and Serum Cytokines of Atopic Dermatitis in Japanese Adults: A Double-Blind, Randomized, Clinical Trial

    • 2015-04-16
    • RCT · n = 49
    • International Archives of Allergy and Immunology 165(4)
    • • Y. Inoue
      • T. Kambara
      • Naoko Murata
      • J. Komori-Yamaguchi
      • S. Matsukura
      • Yukitoshi Takahashi
      • Z. Ikezawa
      • M. Aihara

    • PubMed: 25660281
    • DOI: 10.1159/000369806

    3 Insights on

    • Increased Transforming Growth Factor-β Levels
    • Improved Atopic Dermatitis Symptoms
    • Reduced Eosinophil Count

    • High evidence
• April 20

  • Modulation of the host response by probiotic Lactobacillus brevis CD2 in experimental gingivitis.

    • 2015-04-20
    • RCT · n = 34
    • Oral Diseases 21(6)
    • • Jae-Kwan Lee
      • Kim Sj
      • Ko Sh
      • A. Ouwehand
      • Ma Ds

    • PubMed: 25720615
    • DOI: 10.1111/odi.12332

    2 Insights on

    • Reduced Nitric Oxide Production
    • Reduced Gingival Inflammation

    • High evidence
• April 24

  • Lactobacillus gasseri KS-13, Bifidobacterium bifidum G9-1, and Bifidobacterium longum MM-2 Ingestion Induces a Less Inflammatory Cytokine Profile and a Potentially Beneficial Shift in Gut Microbiota in Older Adults: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study

    • 2015-04-24
    • RCT · n = 32
    • Journal of the American College of Nutrition 34(6)
    • • Samuel J. Spaiser
      • T. Culpepper
      • C. Nieves
      • M. Ukhanova
      • V. Mai
      • S. Percival
      • M. Christman
      • B. Langkamp-Henken

    • PubMed: 25909149
    • DOI: 10.1080/07315724.2014.983249

    10 Insights on

    • Increased Lactic Acid Bacteria Levels
    • Increased Anti-Inflammatory Cytokine Levels
    • Increased Interleukin-10 Levels
    • Increased Fecal Bifidobacteria Levels
    • Increased Fecal Bifidobacteria
    • Reduced Fecal Escherichia coli Levels
    • Maintained CD4+ Lymphocyte Levels
    • Enhanced Interleukin-10 Production
    • Reduced Fecal Escherichia coli Count
    • Reduced Escherichia Coli Levels

    • High evidence
• April 28

  • Protective Effects of a Novel Probiotic Strain of Lactobacillus plantarum JSA22 from Traditional Fermented Soybean Food Against Infection by Salmonella enterica Serovar Typhimurium.

    • 2015-04-28
    • Journal of Microbiology and Biotechnology 25(4)
    • • J. Eom
      • Jin Song
      • H. Choi

    • PubMed: 25639720
    • DOI: 10.4014/JMB.1501.01006

    11 Insights on

    • Reduced Inflammatory Response
    • Reduced Inflammation Levels
    • Reduced Bacterial Infection Severity
    • Reduced Pathogen Growth
    • Reduced Cytotoxicity
    • Reduced Nuclear Factor Kappa B Activation
    • Reduced S. Typhimurium Infection
    • Reduced NF-kappaB Activation due to S. Typhimurium
    • Reduced IL-8 Production
    • Reduced Infection Rate
    • Suppressed Salmonella Typhimurium Infection

    • Low evidence
• Undated – 5 supplement studies

  • Effects of Clostridium butyricum on growth performance, antioxidation, and immune function of broilers.

    • 2015-04
    • RCT
    • Poultry Science 94(4)
    • • Xiudong Liao
      • Ma Guang
      • Jun Cai
      • Yu Fu
      • X. Yan
      • Xubiao Wei
      • Rijun Zhang

    • PubMed: 25717087
    • DOI: 10.3382/ps/pev038

    4 Insights on

    • Improved Immune Function
    • Reduced Hepatic Oxidative Stress
    • Improved Growth Performance
    • Enhanced Antioxidant Activity

    • High evidence
    • Highly Cited
    • Rigorous Journal

  • In vitro evaluation of celluloytic Bacillus amyloliquefaciens AMS1 isolated from traditional fermented soybean (Churpi) as an animal probiotic.

    • 2015-04
    • Research in Veterinary Science 99
    • • A. K. Manhar
      • D. Saikia
      • Y. Bashir
      • Reba K Mech
      • D. Nath
      • B. K. Konwar
      • M. Mandal

    • PubMed: 25660401
    • DOI: 10.1016/j.rvsc.2015.01.008

    2 Insights on

    • Improved Gut Health
    • Improved Digestibility

    • Low evidence

  • Non-viable immunobiotic Lactobacillus rhamnosus CRL1505 and its peptidoglycan improve systemic and respiratory innate immune response during recovery of immunocompromised-malnourished mice.

    • 2015-04
    • Clinical Trial
    • International Immunopharmacology 25(2)
    • • Yanina Kolling
      • S. Salva
      • J. Villena
      • Gabriela Marranzino
      • S. Alvarez

    • PubMed: 25744605
    • DOI: 10.1016/j.intimp.2015.02.006

    6 Insights on

    • Increased Interleukin-10 Levels
    • Enhanced Innate Immune Function
    • Increased IL-10 Levels
    • Enhanced Resistance to Streptococcus Pneumoniae Infection
    • Increased Tumor Necrosis Factor-Alpha Levels
    • Improved Respiratory Immunity

    • Low evidence
    • Rigorous Journal
    • Animal Study

  • Health benefits of fermented milk containing Bifidobacterium bifidum YIT 10347 on gastric symptoms in adults.

    • 2015-04
    • RCT · n = 332
    • Journal of Dairy Science 98(4)
    • • A. Gomi
      • T. Iino
      • C. Nonaka
      • K. Miyazaki
      • F. Ishikawa

    • PubMed: 25648808
    • DOI: 10.3168/jds.2014-9158

    3 Insights on

    • Reduced Abdominal Symptoms
    • Reduced Prevalence of Gastric Symptoms
    • Reduced Gastric Symptoms

    • High evidence
    • Large Human Trial
    • Rigorous Journal

  • Scavenger receptor for lipoteichoic acid is involved in the potent ability of Lactobacillus plantarum strain L-137 to stimulate production of interleukin-12p40.

    • 2015-04
    • International Immunopharmacology 25(2)
    • • S. Hatano
      • Y. Hirose
      • Yoshihiro Yamamoto
      • S. Murosaki
      • Y. Yoshikai

    • PubMed: 25698554
    • DOI: 10.1016/j.intimp.2015.02.011

    1 Insight on

    • Increased Interleukin-12p40 Production

    • Low evidence
    • Rigorous Journal