The Big One without Iron

4.7 (239 reviews)

Out of Stock

Supplement Ingredients
Ingredients	Amount Per Serving
Vitamin A Vitamin A	2,400 mcg RAE
beta carotene Vitamin A	-
palmitate Palmitic Acid	-
Vitamin C Vitamin C	125 mg
ascorbic acid Vitamin C	-
ascorbyl palmitate Ascorbyl Palmitate	-
Vitamin D-3 Vitamin D3	25 mcg
cholecalciferol Vitamin D	1,000 IU
Vitamin E Vitamin E	67 mg
d-Alpha Tocopheryl Acid Succinate Vitamin E	-
Mixed Tocopherols	-
Vitamin K1 Vitamin K1	85 mcg
thiamine Vitamin B1	25 mg
thiamine mononitrate Vitamin B1	-
riboflavin Vitamin B2	25 mg
riboflavin 5'phosphate Vitamin B2	-
niacin Vitamin B3	100 mg
niacinamide Vitamin B3	-
Vitamin B-6 Vitamin B6	25 mg
Pyridoxine HCl Vitamin B6	-
Pyridoxal 5' Phosphate Vitamin B6	-
folate Vitamin B9	667 mcg DFE
L-5-Methylfolate, calcium salt	400 mcg
Vitamin B-12 Vitamin B12	100 mcg
Methylcobalamin Vitamin B12	-
biotin Vitamin B7	200 mcg
pantothenic acid Vitamin B5	100 mg
d-calcium pantothenate Vitamin B5	-
Iodine Iodine	100 mcg
Potassium Iodide Iodine	-
Zinc Zinc	15 mg
Zinc Citrate Zinc	-
selenium Selenium	100 mcg
L-selenomethionine Selenium	-
copper Copper	1 mg
copper gluconate Copper	-
manganese Manganese	5 mg
manganese glycinate	-
chromium Chromium	100 mcg
chromium niacinate Chromium	-
molybdenum Molybdenum	50 mcg
molybdenum glycinate Molybdenum	-
betaine HCL	25 mg
boron Boron	1 mg
boron citrate Boron	-
Vanadium Vanadium	50 mcg
Vanadyl Sulfate Vanadium	-
Vitamin K2 Vitamin K2	15 mcg
K-2 M7	-

Ingredient Research

Vitamin B1
- Very lowImproved Left Ventricular Ejection Fraction3 studies
Vitamin B12
- LowReduced Vitamin B12 Level5 studies
Vitamin B6
- LowReduced Anxiety3 studies
Vitamin B9
- HighReduced Homocysteine Level7 studies
- ModerateIncreased Folate Level3 studies
Vitamin C
- HighReduced Pain7 studies
- ModerateReduced Interleukin-6 Levels6 studies
- ModerateReduced Systolic Blood Pressure4 studies
Vitamin D
- HighIncreased 25-hydroxyvitamin D Level14 studies
- HighReduced Parathyroid Hormone Level4 studies
- ModerateImproved Insulin Sensitivity9 studies
Vitamin E
- ModerateReduced Aspartate Aminotransferase Level5 studies
- ModerateReduced Alanine Aminotransferase Level4 studies
- ModerateReduced Pain3 studies
Selenium
- HighReduced Thyroid Peroxidase Antibody Level5 studies
- LowReduced Thyroglobulin Antibody Level4 studies
- LowImproved Cognitive Function3 studies
Zinc
- LowReduced Zinc Level3 studies

How this product's ingredient doses compare to doses studied in research.

Vitamin C125 mg
Studies used 12–1,200 mg/day (median 250) across 16 studies
Low end of studied doses
Vitamin E67 mg
Studies used 5–1,200 mg/day (median 300) across 10 studies
Low end of studied doses
Form mismatch: this product uses Alpha-Tocopherol. Most research support uses α-Te (1 study).
Vitamin B125 mg
Studies used 0–1,200 mg/day (median 100) across 8 studies
Low end of studied doses
Vitamin B225 mg
Studies used 20–1,200 mg/day (median 100) across 5 studies
Low end of studied doses
Vitamin B3100 mg
Studies used 100–3,000 mg/day (median 714) across 9 studies
Low end of studied doses
Vitamin B625 mg
Studies used 19–1,200 mg/day (median 80) across 6 studies
Low end of studied doses
Vitamin B12100 mcg
Studies used 250–1,000 mcg/day (median 1,000) across 3 studies
Below studied range
Vitamin B7200 mcg
Studies used 10,000 mcg/day (median 10,000) across 1 study
Below studied range
Zinc15 mg
Studies used 10–100 mg/day (median 55) across 2 studies
Low end of studied doses
Chromium100 mcg
Studies used 200–400 mcg/day (median 300) across 2 studies
Below studied range
Vitamin K215 mcg
Studies used 180–360 mcg/day (median 200) across 3 studies
Below studied range

Ingredient pairs in this product that have synthesised research evidence together.

Low evidenceVitamin E + Vitamin Cfor Reduced Pain· 3 studies
Across 3 studies, all reported beneficial effects of the Vitamin E and Vitamin C combination on pain reduction, with effect sizes ranging from small to moderate and all findings statistically significant. Compared to Vitamin C alone (moderate evidence, small effect), the combination shows a similar directional benefit but the limited number of studies precludes a definitive comparison. The median study duration was 60 days (reported in 1 of 3 studies). No form data were reported for either substance.

Comprehensive Multivitamin Support: Supplies essential vitamins and minerals to bolster overall health.
Bone and Immune Health: Rich in Vitamin D3 and Vitamin C to support strong bones and robust immune function.
Energy Booster: B-Vitamins like thiamine, riboflavin, niacin, and Vitamin B12 support energy metabolism and reduce fatigue.
Heart Health: Folate, Vitamin B6, and B12 contribute to cardiovascular health by helping manage homocysteine levels.
Skin and Hair Support: Biotin promotes healthy skin, hair, and nails.
Strong Antioxidant Defense: Vitamin E and Vitamin A provide antioxidant support to combat free radicals.
Thyroid Function: Iodine is crucial for maintaining healthy thyroid function.
Bone Mineralization: Contains Vitamin K2 which is essential for bone health.
Vegetarian and Allergen-Free: Free from gluten, dairy, and eggs, making it suitable for those with dietary restrictions.
Optimal Absorption: Uses L-5-Methylfolate, a bioactive form of folate for better absorption over synthetic forms.
Stress and Cognitive Function: Pantothenic acid plays a role in hormone production and supports brain health.
Convenient Capsule Form: Easy-to-take capsule without added iron for individuals who need to avoid excess iron intake.