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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Acidified Milk Formula Supplemented With Bifidobacterium lactis: Impact on Infant Diarrhea in Residential Care Settings
- 2004-03
- RCT · n = 90
- Journal of Pediatric Gastroenterology and Nutrition 38(3)
- - J. Chouraqui
  - L. Van Egroo
  - M. Fichot
- PubMed: 15076628
- DOI: 10.1097/00005176-200403000-00011
5 Insights on
- High evidence
- Highly Cited
Long-term consumption of infant formulas containing live probiotic bacteria: tolerance and safety.
- 2004-02
- RCT · n = 118
- The American Journal of Clinical Nutrition 79(2)
- - J. Saavedra
  - A. Abi-hanna
  - N. Moore
  - R. Yolken
- PubMed: 14749232
- DOI: 10.1093/AJCN/79.2.261
4 Insights on
- High evidence
- Highly Cited
Colonization and Immunomodulation by Lactobacillus reuteri ATCC 55730 in the Human Gastrointestinal Tract
- 2004-02
- Clinical Trial · n = 19
- Applied and Environmental Microbiology 70(2)
- - N. Valeur
  - P. Engel
  - N. Carbajal
  - E. Connolly
  - K. Ladefoged
- PubMed: 14766603
- DOI: 10.1128/AEM.70.2.1176-1181.2004
8 Insights on
- High evidence
- Highly Cited
Identification and H2O2 Production of Vaginal Lactobacilli from Pregnant Women at High Risk of Preterm Birth and Relation with Outcome
- 2004-02
- Observational
- Journal of Clinical Microbiology 42(2)
- - M. Wilks
  - R. Wiggins
  - A. Whiley
  - E. Hennessy
  - S. Warwick
  - H. Porter
  - A. Corfield
  - M. Millar
- PubMed: 14766841
- DOI: 10.1128/JCM.42.2.713-717.2004
1 Insight on
- Reduced Risk of Chorioamnionitis
- Moderate evidence
- Highly Cited
Lactobacillus bacteremia, clinical significance, and patient outcome, with special focus on probiotic L. rhamnosus GG.
- 2004-01
- n = 89
- Clinical Infectious Diseases 38(1)
- - Minna K. Salminen
  - H. Rautelin
  - S. Tynkkynen
  - T. Poussa
  - M. Saxelin
  - V. Valtonen
  - A. Järvinen
- PubMed: 14679449
- DOI: 10.1086/380455
3 Insights on
- Moderate evidence
- Highly Cited
Saw palmetto and benign prostatic hyperplasia.
- 2004-01
- Review
- The American journal of Chinese medicine 32(03)
- - Edward M Gong
  - Glenn S Gerber
- PubMed: 15344416
- DOI: 10.1142/s0192415x04001989
2 Insights on
- Reduced Lower Urinary Tract Symptom
- Improved Urinary Function
- Low evidence
Immunostimulant properties of a cell wall-modified whole Saccharomyces cerevisiae strain administered by diet to seabream (Sparus aurata L.).
- 2003-12
- RCT
- Veterinary Immunology and Immunopathology 96(3-4)
- - A. Rodríguez
  - A. Cuesta
  - J. Ortuño
  - M. Esteban
  - J. Meseguer
- PubMed: 14592731
- DOI: 10.1016/J.VETIMM.2003.07.001
4 Insights on
- High evidence
- Highly Cited
Comparison of the incidence of virulence determinants and antibiotic resistance between Enterococcus faecium strains of dairy, animal and clinical origin.
- 2003-12
- International Journal of Food Microbiology 88(2-3)
- - L. Mannu
  - A. Paba
  - E. Daga
  - R. Comunian
  - S. Zanetti
  - I. Dupré
  - L. Sechi
- PubMed: 14597001
- DOI: 10.1016/S0168-1605(03)00191-0
1 Insight on
- Increased Risk of Opportunistic Pathogenicity
- Low evidence
- Highly Cited
Occurrence and spread of antibiotic resistances in Enterococcus faecium.
- 2003-12
- International Journal of Food Microbiology 88(2-3)
- - I. Klare
  - C. Konstabel
  - D. Badstübner
  - G. Werner
  - W. Witte
- PubMed: 14597000
- DOI: 10.1016/S0168-1605(03)00190-9
3 Insights on
- Low evidence
- Highly Cited
Safety aspects of enterococci from the medical point of view.
- 2003-12
- International Journal of Food Microbiology 88(2-3)
- - F. Kayser
- PubMed: 14596998
- DOI: 10.1016/S0168-1605(03)00188-0
3 Insights on
- Low evidence
- Highly Cited
Immune enhancement in rainbow trout (Oncorhynchus mykiss) by potential probiotic bacteria (Lactobacillus rhamnosus).
- 2003-11
- Clinical Trial
- Fish & Shellfish Immunology 15(5)
- - Sami Nikoskelainen
  - A. Ouwehand
  - G. Bylund
  - S. Salminen
  - E. Lilius
- PubMed: 14550670
- DOI: 10.1016/S1050-4648(03)00023-8
5 Insights on
- Low evidence
- Highly Cited
- Animal Study
Protection of bifidobacteria encapsulated in polysaccharide-protein gel beads against gastric juice and bile.
- 2003-11
- Journal of Food Protection 66(11)
- - D. Guérin
  - J. Vuillemard
  - M. Subirade
- PubMed: 14627286
- DOI: 10.4315/0362-028X-66.11.2076
2 Insights on
- Improved Survival of Probiotic Bacteria
- Enhanced Bile Salt Resistance
- Low evidence
- Highly Cited
An In Vitro Study of the Probiotic Potential of a Bile-Salt-Hydrolyzing Lactobacillus fermentum Strain, and Determination of Its Cholesterol-Lowering Properties
- 2003-08
- Applied and Environmental Microbiology 69(8)
- - Dora I A Pereira
  - A. McCartney
  - G. Gibson
- PubMed: 12902267
- DOI: 10.1128/AEM.69.8.4743-4752.2003
7 Insights on
- Low evidence
- Highly Cited
Dietary supplementation of fermented soybean, natto, suppresses intimal thickening and modulates the lysis of mural thrombi after endothelial injury in rat femoral artery.
- 2003-07
- Life Sciences 73(10)
- - Yasuhiro Suzuki
  - K. Kondo
  - Y. Matsumoto
  - Bingshun Zhao
  - K. Otsuguro
  - T. Maeda
  - Y. Tsukamoto
  - T. Urano
  - K. Umemura
- PubMed: 12850244
- DOI: 10.1016/S0024-3205(03)00426-0
2 Insights on
- Improved Thrombolytic Property
- Reduced Intimal Thickening
- Low evidence
- Highly Cited
Lactobacillus crispatus Capsules: Single-Use Safety Study in the Macaca nemestrina Model
- 2003-07
- Clinical Trial · n = 10
- Sexually Transmitted Diseases 30(7)
- - D. Patton
  - Y. C. Cosgrove Sweeney
  - M. Antonio
  - L. Rabe
  - S. Hillier
- PubMed: 12838085
- DOI: 10.1097/00007435-200307000-00007
3 Insights on
- Low evidence
- Animal Study
Effects of milk products fermented by Bifidobacterium longum on blood lipids in rats and healthy adult male volunteers.
- 2003-07
- RCT · n = 32
- Journal of Dairy Science 86(7)
- - J. Xiao
  - S. Kondo
  - N. Takahashi
  - K. Miyaji
  - K. Oshida
  - A. Hiramatsu
  - K. Iwatsuki
  - S. Kokubo
  - A. Hosono
- PubMed: 12906063
- DOI: 10.3168/JDS.S0022-0302(03)73839-9
13 Insights on
- High evidence
- Highly Cited
Probiotic and milk technological properties of Lactobacillus brevis.
- 2003-05
- International Journal of Food Microbiology 83(1)
- - Elina Rönkä
  - Erja Malinen
  - M. Saarela
  - M. Rinta-Koski
  - J. Aarnikunnas
  - A. Palva
- PubMed: 12672593
- DOI: 10.1016/S0168-1605(02)00315-X
1 Insight on
- Reduced Harmful Microorganisms
- Low evidence
- Highly Cited
Preparation of spent brewer's yeast beta-glucans with a potential application as an immunostimulant for black tiger shrimp, Penaeus monodon.
- 2003-05
- Bioresource Technology 88(1)
- - M. Suphantharika
  - P. Khunrae
  - P. Thanardkit
  - C. Verduyn
- PubMed: 12573564
- DOI: 10.1016/S0960-8524(02)00257-2
1 Insight on
- Enhanced Phenoloxidase Activity
- Low evidence
- Highly Cited
Persistence of Colonization of Intestinal Mucosa by a Probiotic Strain, Lactobacillus casei subsp. rhamnosus Lcr35, after Oral Consumption
- 2003-03
- RCT · n = 12
- Journal of Clinical Microbiology 41(3)
- - C. de Champs
  - Nathalie Maroncle
  - Damien Balestrino
  - C. Rich
  - C. Forestier
- PubMed: 12624065
- DOI: 10.1128/JCM.41.3.1270-1273.2003
1 Insight on
- Increased Fecal Lactobacilli Population
- High evidence
- Highly Cited
Oral use of Lactobacillus rhamnosus GR-1 and L. fermentum RC-14 significantly alters vaginal flora: randomized, placebo-controlled trial in 64 healthy women.
- 2003-03
- RCT · n = 64
- FEMS Immunology & Medical Microbiology 35(2)
- - G. Reid
  - D. Charbonneau
  - J. Erb
  - B. Kochanowski
  - D. Beuerman
  - Russ Poehner
  - A. Bruce
- PubMed: 12628548
- DOI: 10.1016/S0928-8244(02)00465-0
11 Insights on
- High evidence
- Highly Cited
Probiotic properties of human lactobacilli strains to be used in the gastrointestinal tract.
- 2003-03
- Journal of Applied Microbiology 94(3)
- - M. F. Fernández
  - S. Boris
  - C. Barbés
- PubMed: 12588553
- DOI: 10.1046/J.1365-2672.2003.01850.X
6 Insights on
- Low evidence
- Highly Cited
Divergent Patterns of Colonization and Immune Response Elicited from Two Intestinal Lactobacillus Strains That Display Similar Properties In Vitro
- 2003-01
- Clinical Trial
- Infection and Immunity 71(1)
- - N. Ibnou‐Zekri
  - S. Blum
  - E. Schiffrin
  - T. von der Weid
- PubMed: 12496193
- DOI: 10.1128/IAI.71.1.428-436.2003
2 Insights on
- Increased Mucosal B-Cell Responses
- Increased IgA-Secreting Lymphocytes in the Mucosa
- Low evidence
- Highly Cited
- Animal Study
The antimicrobial properties of different strains of Lactobacillus spp. isolated from kefir.
- 2003-01
- Systematic and Applied Microbiology 26(3)
- - Antonio Santos
  - M. Mauro
  - A. Sanchez
  - J. Torres
  - D. Marquina
- PubMed: 14529186
- DOI: 10.1078/072320203322497464
3 Insights on
- Low evidence
- Highly Cited
Effect of Lactobacillus plantarum 299v on cardiovascular disease risk factors in smokers.
- 2002-12
- RCT · n = 36
- The American Journal of Clinical Nutrition 76(6)
- - M. Naruszewicz
  - M. Johansson
  - D. Zapolska-Downar
  - H. Bukowska
- PubMed: 12450890
- DOI: 10.1093/AJCN/76.6.1249
8 Insights on
- High evidence
- Highly Cited
Effect of different probiotic preparations on anti-Helicobacter pylori therapy-related side effects: a parallel group, triple blind, placebo-controlled study
- 2002-11
- RCT · n = 85
- The American Journal of Gastroenterology 97(11)
- - F. Cremonini
  - S. Caro
  - M. Covino
  - A. Armuzzi
  - M. Gabrielli
  - L. Santarelli
  - E. Nista
  - G. Cammarota
  - G. Gasbarrini
  - A. Gasbarrini
- PubMed: 12425542
- DOI: 10.1111/j.1572-0241.2002.07063.x
5 Insights on
- High evidence
- Highly Cited
Effect of Lactobacillus johnsonii La1 and antioxidants on intestinal flora and bacterial translocation in rats with experimental cirrhosis.
- 2002-10
- RCT · n = 66
- Journal of Hepatology 37(4)
- - M. Chiva
  - G. Soriano
  - I. Rochat
  - C. Peralta
  - F. Rochat
  - T. Llovet
  - B. Mirelis
  - E. Schiffrin
  - C. Guarner
  - Joaquím Balanzó
- PubMed: 12217598
- DOI: 10.1016/S0168-8278(02)00142-3
6 Insights on
- Low evidence
- Highly Cited
- Animal Study
Immune protection mediated by the probiotic Lactobacillus rhamnosus HN001 (DR20) against Escherichia coli O157:H7 infection in mice.
- 2002-09
- Clinical Trial
- FEMS Immunology & Medical Microbiology 34(1)
- - Q. Shu
  - H. Gill
- PubMed: 12208607
- DOI: 10.1111/J.1574-695X.2002.TB00603.X
7 Insights on
- Low evidence
- Highly Cited
- Animal Study
Lactobacillus casei strain Shirota suppresses serum immunoglobulin E and immunoglobulin G1 responses and systemic anaphylaxis in a food allergy model
- 2002-04
- Clinical & Experimental Allergy 32(4)
- - K. Shida
  - R. Takahashi
  - E. Iwadate
  - K. Takamizawa
  - H. Yasui
  - Takehito Sato
  - S. Habu
  - S. Hachimura
  - S. Kaminogawa
- PubMed: 11972603
- DOI: 10.1046/j.0954-7894.2002.01354.x
1 Insight on
- Reduced Systemic Anaphylaxis
- Low evidence
- Highly Cited
No effect of oral treatment with an intestinal bacterial strain, Lactobacillus rhamnosus (ATCC 53103), on birch‐pollen allergy: a placebo‐controlled double‐blind study
- 2002-03
- RCT
- Allergy 57(3)
- - T. Helin
  - Sauli Haahtela
  - T. Haahtela
- PubMed: 11906339
- DOI: 10.1034/j.1398-9995.2002.1s3299.x
9 Insights on
- High evidence
- Highly Cited
Two antioxidative lactobacilli strains as promising probiotics.
- 2002-02
- International Journal of Food Microbiology 72(3)
- - T. Kullisaar
  - M. Zilmer
  - M. Mikelsaar
  - T. Vihalemm
  - H. Annuk
  - C. Kairane
  - A. Kilk
- PubMed: 11845820
- DOI: 10.1016/S0168-1605(01)00674-2
1 Insight on
- Enhanced Reactive Oxygen Species Resistance
- Low evidence
- Highly Cited