August 2017 Supplement Research Papers

• August 3

  • Interplay between Lactobacillus rhamnosus GG and Candida and the involvement of exopolysaccharides

    • 2017-08-03
    • Microbial Biotechnology 10(6)
    • • C. Allonsius
      • M. V. D. van den Broek
      • I. De Boeck
      • Shari Kiekens
      • E. Oerlemans
      • F. Kiekens
      • K. Foubert
      • Dieter Vandenheuvel
      • P. Cos
      • P. Delputte
      • S. Lebeer

    • PubMed: 28772020
    • DOI: 10.1111/1751-7915.12799

    3 Insights on

    • Inhibited Growth of Candida Species
    • Reduced Candida Albicans Hyphal Formation
    • Reduced Candida Morphogenesis

    • Low evidence
    • Highly Cited
• August 8

  • In Vitro and In Vivo Evaluation of Lactobacillus delbrueckii subsp. bulgaricus KLDS1.0207 for the Alleviative Effect on Lead Toxicity

    • 2017-08-08
    • Nutrients 9(8)
    • • Bailiang Li
      • Da Jin
      • Shang-fu Yu
      • Smith Etareri Evivie
      • Zafarullah Muhammad
      • G. Huo
      • Fei Liu

    • PubMed: 28786945
    • DOI: 10.3390/nu9080845

    4 Insights on

    • Reduced Mortality Risk
    • Increased Lead Excretion
    • Reduced Tissue Lead Levels
    • Reduced Renal Pathological Damage

    • Moderate evidence
• August 10

  • Peptidoglycan from Immunobiotic Lactobacillus rhamnosus Improves Resistance of Infant Mice to Respiratory Syncytial Viral Infection and Secondary Pneumococcal Pneumonia

    • 2017-08-10
    • Clinical Trial
    • Frontiers in Immunology 8
    • • Patricia Clua
      • P. Kanmani
      • H. Zelaya
      • A. Tada
      • A. Kober
      • S. Salva
      • S. Alvarez
      • S. Alvarez
      • H. Kitazawa
      • J. Villena
      • J. Villena

    • PubMed: 28848552
    • DOI: 10.3389/fimmu.2017.00948

    3 Insights on

    • Improved Resistance to RSV Infection
    • Improved Resistance to Secondary Pneumococcal Pneumonia
    • Increased Lung CD3+CD4+ IFN-γ+ T Cells

    • Low evidence
    • Animal Study
• August 18

  • Lactobacillus helveticus-fermented milk containing lactononadecapeptide (NIPPLTQTPVVVPPFLQPE) improves cognitive function in healthy middle-aged adults: a randomised, double-blind, placebo-controlled trial

    • 2017-08-18
    • RCT
    • International Journal of Food Sciences and Nutrition 69(3)
    • • K. Ohsawa
      • F. Nakamura
      • Naoto Uchida
      • S. Mizuno
      • H. Yokogoshi

    • PubMed: 28819993
    • DOI: 10.1080/09637486.2017.1365824

    4 Insights on

    • Improved Cognitive Function
    • Improved Attention Span
    • Improved Delayed Memory
    • Improved Memory Function

    • High evidence
• August 23

  • Lactobacillus plantarum Strains Can Enhance Human Mucosal and Systemic Immunity and Prevent Non-steroidal Anti-inflammatory Drug Induced Reduction in T Regulatory Cells

    • 2017-08-23
    • RCT
    • Frontiers in Immunology 8
    • • P. de Vos
      • Z. Mujagic
      • B. de Haan
      • R. Siezen
      • P. Bron
      • M. Meijerink
      • J. Wells
      • A. Masclee
      • M. Boekschoten
      • M. Faas
      • F. Troost

    • PubMed: 28878772
    • DOI: 10.3389/fimmu.2017.01000

    6 Insights on

    • Increased Regulatory T-Cells
    • Increased Regulatory T Cell Count
    • Enhanced Immune Memory
    • Improved Memory Response to Tetanus Toxoid Antigen
    • Enhanced Immune Response Against Specific Bacteria
    • Reduced Immunological Pathway Activity in Antigen Presentation

    • High evidence
• August 24

  • Probiotic Bifidobacterium bifidum G9‐1 attenuates 5‐fluorouracil‐induced intestinal mucositis in mice via suppression of dysbiosis‐related secondary inflammatory responses

    • 2017-08-24
    • Clinical Trial
    • Clinical and Experimental Pharmacology and Physiology 44(10)
    • • S. Kato
      • N. Hamouda
      • Yoshitaro Kano
      • Yousuke Oikawa
      • Yoshiki Tanaka
      • Kenjiro Matsumoto
      • K. Amagase
      • M. Shimakawa

    • PubMed: 28590519
    • DOI: 10.1111/1440-1681.12792

    3 Insights on

    • Improved Gut Microbiota Structure
    • Reduced Inflammation
    • Reduced Intestinal Mucositis Severity

    • Low evidence
    • Animal Study

  • Streptococcus thermophilus NCIMB 41856 ameliorates signs of colitis in an animal model of inflammatory bowel disease.

    • 2017-08-24
    • Clinical Trial
    • Beneficial Microbes 8(4)
    • • J. Bailey
      • Valérie Vince
      • Neil Williams
      • T. Cogan

    • PubMed: 28618865
    • DOI: 10.3920/BM2016.0110

    5 Insights on

    • Reduced Bacterial Translocation
    • Delayed Onset of Colitis
    • Reduced Clinical Disease Signs
    • Increased Intraepithelial CD8+ Lymphocytes
    • No Significant Effect on Gross Pathology

    • Low evidence
    • Animal Study
• August 29

  • Differential intestinal anti-inflammatory effects of Lactobacillus fermentum and Lactobacillus salivarius in DSS mouse colitis: impact on microRNAs expression and microbiota composition.

    • 2017-08-29
    • RCT · n = 10
    • Molecular Nutrition & Food Research 61(11)
    • • A. Rodríguez‐Nogales
      • F. Algieri
      • J. Garrido-Mesa
      • T. Vezza
      • M. P. Utrilla
      • N. Chueca
      • Federico García
      • M. Olivares
      • M. Rodríguez-Cabezas
      • J. Gálvez

    • PubMed: 28752563
    • DOI: 10.1002/mnfr.201700144

    12 Insights on

    • Improved Gut Microbiota Composition
    • Improved Immune Response
    • Improved Gut Microbiota Balance
    • Improved Colonic Health
    • Improved Macroscopic Colonic Damage
    • Restored Intestinal Barrier Function
    • Improved Microbial Diversity
    • Restored Regulatory T Cell Population
    • Restored Regulatory T Cell Population in Mesenteric Lymph Nodes
    • Restored Th1/Th2 Cytokine Balance
    • Improved Colonic Immune Response
    • Restored Treg Cell Population in MLNs

    • Low evidence
    • Highly Cited
    • Animal Study

  • Dual function of Lactobacillus kefiri DH5 in preventing high-fat-diet-induced obesity: direct reduction of cholesterol and upregulation of PPAR-α in adipose tissue.

    • 2017-08-29
    • Clinical Trial
    • Molecular Nutrition & Food Research 61(11)
    • • Dong‐Hyeon Kim
      • Dana Jeong
      • Il‐Byeong Kang
      • Hyunsook Kim
      • K. Song
      • K. Seo

    • PubMed: 28691342
    • DOI: 10.1002/mnfr.201700252

    7 Insights on

    • Reduced Body Weight
    • Reduced Triglyceride Levels
    • Reduced LDL Cholesterol
    • Reduced Epididymal Fat Mass
    • Reduced Hepatic Steatosis
    • Reduced Adipose Tissue
    • Reduced Adipocyte Diameter

    • Low evidence
    • Highly Cited
    • Animal Study
• Undated – 1 supplement study

  • Probiotic Bifidobacterium longum NCC3001 Reduces Depression Scores and Alters Brain Activity: A Pilot Study in Patients With Irritable Bowel Syndrome.

    • 2017-08
    • RCT · n = 44
    • Gastroenterology 153(2)
    • • M. Pinto-Sanchez
      • G. Hall
      • K. Ghajar
      • A. Nardelli
      • C. Bolino
      • Jennifer T. Lau
      • F. Martin
      • O. Cominetti
      • Christopher Welsh
      • A. Rieder
      • J. Traynor
      • Caitlin Gregory
      • G. De Palma
      • M. Pigrau
      • A. Ford
      • J. Macri
      • B. Berger
      • G. Bergonzelli
      • M. Surette
      • S. Collins
      • P. Moayyedi
      • P. Bercik

    • PubMed: 28483500
    • DOI: 10.1053/j.gastro.2017.05.003

    10 Insights on

    • Improved Quality of Life
    • Reduced Depression Symptoms
    • Reduced Limbic System Reactivity
    • No Change in Anxiety
    • Improved Health-related Quality of Life
    • Reduced Negative Emotional Responses
    • Altered Brain Activity to Negative Emotional Stimuli
    • Improved Brain Activity
    • No Significant Effect on Anxiety Levels
    • Reduced Depression Scores at Follow-Up

    • High evidence
    • Highly Cited