Skip to main content

Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Effect of fermented milk containing Lactobacillus rhamnosus SD11 on oral microbiota of healthy volunteers: A randomized clinical trial.
- 2017-10
- RCT · n = 43
- Journal of Dairy Science 100(10)
- - P. Rungsri
  - N. Akkarachaneeyakorn
  - Mutita Wongsuwanlert
  - S. Piwat
  - P. Nantarakchaikul
  - R. Teanpaisan
- PubMed: 28803012
- DOI: 10.3168/jds.2017-12961
15 Insights on
- High evidence
- Rigorous Journal
Dietary Bacillus subtilis-based direct-fed microbials alleviate LPS-induced intestinal immunological stress and improve intestinal barrier gene expression in commercial broiler chickens.
- 2017-10
- RCT
- Research in Veterinary Science 114
- - U. Gadde
  - Sungtaek Oh
  - Youngsub Lee
  - E. Davis
  - N. Zimmerman
  - T. Rehberger
  - H. Lillehoj
- PubMed: 28505587
- DOI: 10.1016/j.rvsc.2017.05.004
4 Insights on
- Low evidence
- Highly Cited
- Animal Study
Effect of Lactobacillus rhamnosus HN001 in Pregnancy on Postpartum Symptoms of Depression and Anxiety: A Randomised Double-blind Placebo-controlled Trial
- 2017-10
- RCT · n = 423
- EBioMedicine 24
- - R. Slykerman
  - Fiona Hood
  - K. Wickens
  - John F. Thompson
  - C. Barthow
  - R. Murphy
  - Janice Kang
  - Judy Rowden
  - P. Stone
  - Julian Crane
  - T. Stanley
  - P. Abels
  - G. Purdie
  - Robyn M. Maude
  - E. Mitchell
- PubMed: 28943228
- DOI: 10.1016/j.ebiom.2017.09.013
7 Insights on
- High evidence
- Large Human Trial
- Highly Cited
- Rigorous Journal
Impact of lyophilized Lactobacillus salivarius DSPV 001P administration on growth performance, microbial translocation, and gastrointestinal microbiota of broilers reared under low ambient temperature.
- 2017-10
- RCT
- Research in Veterinary Science 114
- - J. Blajman
  - C. Olivero
  - M. L. Fusari
  - J. Zimmermann
  - E. Rossler
  - A. Berisvil
  - A. R. Scharpen
  - D. Astesana
  - L. Soto
  - Marcelo Signorini
  - M. V. Zbrun
  - L. Frizzo
- PubMed: 28743079
- DOI: 10.1016/j.rvsc.2017.07.011
6 Insights on
- High evidence
Cytokine production in vitro and in rat model of colitis in response to Lactobacillus plantarum LS/07.
- 2017-10
- Clinical Trial
- Biomedicine & Pharmacotherapy 94
- - Jana Štofilová
  - T. Langerholc
  - C. Botta
  - P. Treven
  - L. Gradišnik
  - Rastislav Salaj
  - A. Šoltésová
  - I. Bertková
  - Z. Hertelyová
  - A. Bomba
- PubMed: 28830068
- DOI: 10.1016/j.biopha.2017.07.138
3 Insights on
- Low evidence
- Rigorous Journal
- Animal Study
Consumption effect of a synbiotic beverage made from soy and yacon extracts containing Bifidobacterium animalis ssp. lactis BB-12 on the intestinal polyamine concentrations in elderly individuals.
- 2017-09
- RCT · n = 29
- Food Research International 99
- - M. Manzoni
  - E. Rossi
  - N. D. Pauly-Silveira
  - R. A. Pinto
  - M. N. Roselino
  - I. Carlos
  - M. B. Quilles
  - Maria Beatriz de Abreu Glória
  - D. Cavallini
- PubMed: 28784510
- DOI: 10.1016/j.foodres.2017.06.005
11 Insights on
- High evidence
Microbiological, biochemical, and functional aspects of sugary kefir fermentation - A review.
- 2017-09
- Review
- Food Microbiology 66
- - F. A. Fiorda
  - G. V. de Melo Pereira
  - V. Thomaz-Soccol
  - S. Rakshit
  - M. Pagnoncelli
  - L. Vandenberghe
  - C. Soccol
- PubMed: 28576377
- DOI: 10.1016/j.fm.2017.04.004
4 Insights on
- Moderate evidence
- Highly Cited
Complete genome sequence of the Bifidobacterium animalis subspecies lactis BL3, preventive probiotics for acute colitis and colon cancer
- 2017-09
- New Microbes and New Infections 19
- - Jisu Kang
  - Won-Hyong Chung
  - Tae-Joong Lim
  - S. Lim
  - Y. Nam
- PubMed: 28702200
- DOI: 10.1016/j.nmni.2017.05.012
4 Insights on
- Low evidence
Effects of Lactobacillus delbrueckii on immune response, disease resistance against Aeromonas hydrophila, antioxidant capability and growth performance of Cyprinus carpio Huanghe var
- 2017-09
- RCT
- Fish & Shellfish Immunology 68
- - Chunnuan Zhang
  - Ji-liang Zhang
  - Wen-Chao Guan
  - Xiao-Fei Zhang
  - Suhong Guan
  - Qing-Hui Zeng
  - G. Cheng
  - Wei Cui
- PubMed: 28698125
- DOI: 10.1016/j.fsi.2017.07.012
5 Insights on
- High evidence
Effects of Probiotics on Necrotizing Enterocolitis, Sepsis, Intraventricular Hemorrhage, Mortality, Length of Hospital Stay, and Weight Gain in Very Preterm Infants: A Meta-Analysis.
- 2017-09
- Meta-Analysis
- Advances in Nutrition 8(5)
- - Jing Sun
  - Gayatri Marwah
  - Matthew M P Westgarth
  - N. Buys
  - D. Ellwood
  - P. Gray
- PubMed: 28916575
- DOI: 10.3945/an.116.014605
6 Insights on
- High evidence
- Highly Cited
Effects of Anthocyanins on Cardiometabolic Health: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
- 2017-09
- Meta-Analysis · n = 1,491
- Advances in nutrition (Bethesda, Md.) 8(5)
- - LiPing Yang
  - WenHua Ling
  - ZhiCheng Du
  - YuMing Chen
  - Dan Li
  - ShiZhou Deng
  - ZhaoMin Liu
  - LiLi Yang
- PubMed: 28916569
- DOI: 10.3945/an.116.014852
5 Insights on
- High evidence
- Highly Cited
Is white rice consumption a risk for metabolic and cardiovascular outcomes? A systematic review and meta-analysis.
- 2017-08
- Meta-Analysis · n = 59
- Heart Asia 9(2)
- - Chayakrit Krittanawong
  - Anusith Tunhasiriwet
  - HongJu Zhang
  - Larry J Prokop
  - Sakkarin Chirapongsathorn
  - Tao Sun
  - Zhen Wang
- PubMed: 29467837
- DOI: 10.1136/heartasia-2017-010909
4 Insights on
- High evidence
Effect of Gymnema sylvestre Administration on Metabolic Syndrome, Insulin Sensitivity, and Insulin Secretion.
- 2017-08
- RCT · n = 600
- Journal of medicinal food 20(8)
- - Laura Y Zuñiga
  - Manuel González-Ortiz
  - Esperanza Martínez-Abundis
- PubMed: 28459647
- DOI: 10.1089/jmf.2017.0001
5 Insights on
- High evidence
- Large Human Trial
Probiotic Bifidobacterium longum NCC3001 Reduces Depression Scores and Alters Brain Activity: A Pilot Study in Patients With Irritable Bowel Syndrome.
- 2017-08
- RCT · n = 44
- Gastroenterology 153(2)
- - M. Pinto-Sanchez
  - G. Hall
  - K. Ghajar
  - A. Nardelli
  - C. Bolino
  - Jennifer T. Lau
  - F. Martin
  - O. Cominetti
  - Christopher Welsh
  - A. Rieder
  - J. Traynor
  - Caitlin Gregory
  - G. De Palma
  - M. Pigrau
  - A. Ford
  - J. Macri
  - B. Berger
  - G. Bergonzelli
  - M. Surette
  - S. Collins
  - P. Moayyedi
  - P. Bercik
- PubMed: 28483500
- DOI: 10.1053/j.gastro.2017.05.003
10 Insights on
- High evidence
- Highly Cited
Replacement of Refined Starches and Added Sugars with Egg Protein and Unsaturated Fats Increases Insulin Sensitivity and Lowers Triglycerides in Overweight or Obese Adults with Elevated Triglycerides.
- 2017-07
- RCT · n = 14
- The Journal of nutrition 147(7)
- - Kevin C Maki
  - Orsolya M Palacios
  - Emily Lindner
  - Kristin M Nieman
  - Marjorie Bell
  - Jennifer Sorce
- PubMed: 28515160
- DOI: 10.3945/jn.117.248641
4 Insights on
- High evidence
Evolving herbal formulations in management of dengue fever.
- 2017-07
- Review
- Journal of Ayurveda and integrative medicine 8(3)
- - Pawan Kumar Singh
  - Pooja Rawat
- PubMed: 28823790
- DOI: 10.1016/j.jaim.2017.06.005
1 Insight on
- Increased Platelet Count
- Low evidence
Paraprobiotic preparation from Bacillus amyloliquefaciens FPTB16 modulates immune response and immune relevant gene expression in Catla catla (Hamilton, 1822)
- 2017-07
- Fish & Shellfish Immunology 66
- - Sukham Tushiba Singh
  - D. Kamilya
  - Biswanath Kheti
  - Biswajyoti Bordoloi
  - J. Parhi
- PubMed: 28476667
- DOI: 10.1016/j.fsi.2017.05.005
5 Insights on
- Low evidence
Dextran production by Lactobacillus sakei MN1 coincides with reduced autoagglutination, biofilm formation and epithelial cell adhesion.
- 2017-07
- Carbohydrate Polymers 168
- - Montserrat Nácher-Vázquez
  - I. Iturria
  - K. Zarour
  - M. Mohedano
  - R. Aznar
  - M. Pardo
  - P. López
- PubMed: 28457443
- DOI: 10.1016/j.carbpol.2017.03.024
1 Insight on
- Enhanced Protection Against Infection
- Low evidence
Effect of Synbiotic on the Gut Microbiota of Cesarean Delivered Infants: A Randomized, Double-blind, Multicenter Study.
- 2017-07
- RCT · n = 60
- Journal of Pediatric Gastroenterology and Nutrition 65(1)
- - M. C. Chua
  - K. Ben-Amor
  - C. Lay
  - A. G. E. Neo
  - Wei Chin Chiang
  - R. Rao
  - Charmaine Chew
  - S. Chaithongwongwatthana
  - N. Khemapech
  - J. Knol
  - V. Chongsrisawat
- PubMed: 28644357
- DOI: 10.1097/MPG.0000000000001623
5 Insights on
- High evidence
Efficacy and Safety of Lactobacillus plantarum DSM 9843 (LP299V) in the Prevention of Antibiotic‐Associated Gastrointestinal Symptoms in Children—Randomized, Double‐Blind, Placebo‐Controlled Study
- 2017-07
- RCT · n = 438
- The Journal of Pediatrics 186
- - A. Olek
  - M. Woynarowski
  - I. L. Ahrén
  - J. Kierkuś
  - P. Socha
  - N. Larsson
  - G. Önning
- PubMed: 28438377
- DOI: 10.1016/j.jpeds.2017.03.047
9 Insights on
- High evidence
- Large Human Trial
Effect of Manuka Honey on Eyelid Wound Healing: A Randomized Controlled Trial.
- 2017-07
- RCT · n = 46
- Ophthalmic plastic and reconstructive surgery 33(4)
- - Raman Malhotra
  - Kimia Ziahosseini
  - Cornelia Poitelea
  - Andre Litwin
  - Suresh Sagili
- PubMed: 27429228
- DOI: 10.1097/iop.0000000000000743
5 Insights on
- High evidence
Study of Bacillus subtilis on growth performance, nutrition metabolism and intestinal microflora of 1 to 42 d broiler chickens
- 2017-06
- RCT · n = 800
- Animal Nutrition 3(2)
- - Zhenhua Gao
  - Haohao Wu
  - Lin Shi
  - Xiaohui Zhang
  - R. Sheng
  - Fuquan Yin
  - R. Gooneratne
- PubMed: 29767043
- DOI: 10.1016/j.aninu.2017.02.002
9 Insights on
- Low evidence
- Rigorous Journal
- Animal Study
Factors influencing ruminal bacterial community diversity and composition and microbial fibrolytic enzyme abundance in lactating dairy cows with a focus on the role of active dry yeast.
- 2017-06
- RCT
- Journal of Dairy Science 100(6)
- - O. Alzahal
  - Fuyong Li
  - L. Guan
  - N. Walker
  - B. McBride
- PubMed: 28390722
- DOI: 10.3168/jds.2016-11473
1 Insight on
- Increased Abundance of Microbial Fibrolytic Enzymes
- High evidence
- Rigorous Journal
Effect of dietary Clostridium butyricum on growth, intestine health status and resistance to ammonia stress in Pacific white shrimp Litopenaeus vannamei
- 2017-06
- Fish & Shellfish Immunology 65
- - Yafei Duan
  - Yue Zhang
  - Hong-biao Dong
  - Yun Wang
  - Xiaoting Zheng
  - Jiasong Zhang
- PubMed: 28359948
- DOI: 10.1016/j.fsi.2017.03.048
4 Insights on
- Low evidence
- Highly Cited
Timely Use of Probiotics in Hospitalized Adults Prevents Clostridium difficile Infection: A Systematic Review With Meta-Regression Analysis.
- 2017-06
- Meta-Analysis
- Gastroenterology 152(8)
- - Nicole T. Shen
  - A. Maw
  - L. Tmanova
  - A. Pino
  - K. Ancy
  - C. Crawford
  - M. Simon
  - A. Evans
- PubMed: 28192108
- DOI: 10.1053/j.gastro.2017.02.003
2 Insights on
- Increased Adverse Events
- Reduced Clostridium difficile Infection
- High evidence
- Highly Cited
Extensively hydrolyzed casein formula containing Lactobacillus rhamnosus GG reduces the occurrence of other allergic manifestations in children with cow's milk allergy: 3‐year randomized controlled trial
- 2017-06
- RCT · n = 220
- Journal of Allergy and Clinical Immunology 139(6)
- - R. B. Canani
  - M. Di Costanzo
  - G. Bedogni
  - Antonio Amoroso
  - L. Cosenza
  - C. di Scala
  - V. Granata
  - R. Nocerino
- PubMed: 28043872
- DOI: 10.1016/j.jaci.2016.10.050
6 Insights on
- High evidence
- Highly Cited
Adsorption of aflatoxin B1, zearalenone and ochratoxin A by microorganisms isolated from Kefir grains.
- 2017-06
- International Journal of Food Microbiology 251
- - F. B. Taheur
  - Kais Fedhila
  - K. Chaieb
  - Bochra Kouidhi
  - A. Bakhrouf
  - L. Abrunhosa
- PubMed: 28376398
- DOI: 10.1016/j.ijfoodmicro.2017.03.021
2 Insights on
- Reduced Cytotoxic Effects
- Reduced Gastrointestinal Absorption of Mycotoxins
- Low evidence
- Highly Cited
Lactobacillus reuteri DSM 17938 in the Treatment of Functional Abdominal Pain in Children: RCT Study.
- 2017-06
- RCT · n = 55
- Journal of pediatric gastroenterology and nutrition 64(6)
- - Oleg Jadrešin
  - Iva Hojsak
  - Zrinjka Mišak
  - Alemka Jaklin Kekez
  - Tena Trbojević
  - Lana Ivković
  - Sanja Kolaček
- PubMed: 27906800
- DOI: 10.1097/mpg.0000000000001478
4 Insights on
- High evidence
Kefir alleviates obesity and hepatic steatosis in high-fat diet-fed mice by modulation of gut microbiota and mycobiota: targeted and untargeted community analysis with correlation of biomarkers.
- 2017-06
- RCT
- The Journal of Nutritional Biochemistry 44
- - Dong‐Hyeon Kim
  - Hyunsook Kim
  - Dana Jeong
  - Il‐Byeong Kang
  - Jung-Whan Chon
  - Hong-Seok Kim
  - K. Song
  - K. Seo
- PubMed: 28384519
- DOI: 10.1016/j.jnutbio.2017.02.014
8 Insights on
- Low evidence
- Highly Cited
- Animal Study
Effects of long‐term Bacillus subtilis CGMCC 1.921 supplementation on performance, egg quality, and fecal and cecal microbiota of laying hens
- 2017-05
- RCT
- Poultry Science 96(5)
- - J. R. Guo
  - X. Dong
  - S. Liu
  - J. Tong
- PubMed: 27789747
- DOI: 10.3382/ps/pew389
4 Insights on
- High evidence
- Rigorous Journal