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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Bifidobacteria and Their Health-Promoting Effects.
- 2017-05-19
- Microbiology Spectrum 5(3)
- - C. Hidalgo-Cantabrana
  - S. Delgado
  - L. Ruiz
  - P. Ruas-Madiedo
  - B. Sánchez
  - A. Margolles
- PubMed: 28643627
- DOI: 10.1128/microbiolspec.BAD-0010-2016
2 Insights on
- Improved Immune System Maturation
- Increased Bifidobacterial Development
- Low evidence
- Highly Cited
The Genomic Basis of Lactobacilli as Health-Promoting Organisms.
- 2017-05-19
- Microbiology Spectrum 5(3)
- - E. Salvetti
  - P. O’Toole
- PubMed: 28643623
- DOI: 10.1128/microbiolspec.BAD-0011-2016
2 Insights on
- Improved Overall Health
- Increased Longevity
- Low evidence
Study protocol: evaluation of the probiotic Lactobacillus Fermentum CECT5716 for the prevention of mastitis in breastfeeding women: a randomised controlled trial.
- 2017-05-19
- RCT · n = 600
- BMC pregnancy and childbirth 17(1)
- - Diana M Bond
  - Jonathan M Morris
  - Natasha Nassar
- PubMed: 28525984
- DOI: 10.1186/s12884-017-1330-8
3 Insights on
- High evidence
- Large Human Trial
Deleterious Metabolic Effects of High Fructose Intake: The Preventive Effect of Lactobacillus kefiri Administration
- 2017-05-17
- Clinical Trial
- Nutrients 9(5)
- - M. G. Zubiría
  - S. Gambaro
  - María Amanda Rey
  - P. Carasi
  - M. Serradell
  - A. Giovambattista
- PubMed: 28513533
- DOI: 10.3390/nu9050470
7 Insights on
- Low evidence
- Animal Study
Cheese supplemented with probiotics reduced the Candida levels in denture wearers-RCT.
- 2017-05-16
- RCT
- Oral diseases 23(7)
- - T Y Miyazima
  - K H Ishikawa
  - Mpa Mayer
  - Smi Saad
  - Aem Nakamae
- PubMed: 28346730
- DOI: 10.1111/odi.12669
1 Insight on
- Reduced Oral Candida Level
- High evidence
Modulation of gut microbiota and increase in fecal water content in mice induced by administration of Lactobacillus kefiranofaciens DN1.
- 2017-05-08
- RCT · n = 16
- Food & Function 8(2)
- - Dana Jeong
  - Dong‐Hyeon Kim
  - Il‐Byeong Kang
  - Hyunsook Kim
  - K. Song
  - Hong-Seok Kim
  - K. Seo
- PubMed: 28121325
- DOI: 10.1039/c6fo01559j
4 Insights on
- Low evidence
- Animal Study
L-carnosine as an adjuvant to fluvoxamine in treatment of obsessive compulsive disorder: A randomized double-blind study.
- 2017-05-08
- RCT
- Human psychopharmacology 32(4)
- - Somaye Arabzadeh
  - Maryam Shahhossenie
  - Bita Mesgarpour
  - Farzin Rezaei
  - Mohammad Reza Shalbafan
  - Zahra Ghiasi
  - Shahin Akhondzadeh
- PubMed: 28485008
- DOI: 10.1002/hup.2584
1 Insight on
- Reduced Obsessive-Compulsive Symptoms
- High evidence
Effect of dietary supplementation with Lactobacillus acidophilus D2/CSL (CECT 4529) on caecum microbioma and productive performance in broiler chickens
- 2017-05-04
- PLOS ONE 12(5)
- - A. De Cesare
  - F. Sirri
  - G. Manfreda
  - Paola Moniaci
  - A. Giardini
  - M. Zampiga
  - A. Meluzzi
- PubMed: 28472118
- DOI: 10.1371/journal.pone.0176309
8 Insights on
- Moderate evidence
- Highly Cited
- Rigorous Journal
Supplementation with [6S]-5-methyltetrahydrofolate or folic acid equally reduces serum homocysteine concentrations in older adults.
- 2017-05-02
- RCT
- International journal of food sciences and nutrition 69(1)
- - Ewa Sicińska
  - Anna Brzozowska
  - Anna Brzozowska
  - Wojciech Roszkowski
  - Paul M Finglas
- PubMed: 28460586
- DOI: 10.1080/09637486.2017.1320536
1 Insight on
- Reduced Homocysteine Level
- High evidence
Effects of a Lactobacillus salivarius mixture on performance, intestinal health and serum lipids of broiler chickens
- 2017-05-01
- Clinical Trial
- PLOS ONE 12(5)
- - P. Shokryazdan
  - Mohammad Faseleh Jahromi
  - J. Liang
  - K. Ramasamy
  - C. C. Sieo
  - Y. Ho
- PubMed: 28459856
- DOI: 10.1371/journal.pone.0175959
7 Insights on
- Low evidence
- Highly Cited
- Rigorous Journal
- Animal Study
Beneficial effects of Lactobacillus casei strain Shirota on academic stress-induced sleep disturbance in healthy adults: a double-blind, randomised, placebo-controlled trial.
- 2017-04-26
- RCT · n = 94
- Beneficial Microbes 8(2)
- - M. Takada
  - K. Nishida
  - Y. Gondo
  - H. Kikuchi-Hayakawa
  - H. Ishikawa
  - K. Suda
  - M. Kawai
  - R. Hoshi
  - Y. Kuwano
  - K. Miyazaki
  - K. Rokutan
- PubMed: 28443383
- DOI: 10.3920/BM2016.0150
6 Insights on
- High evidence
- Highly Cited
Lactobacillus rhamnosus NCDC17 ameliorates type-2 diabetes by improving gut function, oxidative stress and inflammation in high-fat-diet fed and streptozotocintreated rats.
- 2017-04-26
- Clinical Trial
- Beneficial Microbes 8(2)
- - Satvinder Singh
  - R. Sharma
  - S. Malhotra
  - R. Pothuraju
  - U. Shandilya
- PubMed: 28008783
- DOI: 10.3920/BM2016.0090
5 Insights on
- Low evidence
- Animal Study
Bifidobacterium animalis subsp. lactis 420 mitigates the pathological impact of myocardial infarction in the mouse.
- 2017-04-26
- Clinical Trial
- Beneficial Microbes 8(2)
- - Christiane Danilo
  - E. Constantopoulos
  - Laurel A. K. McKee
  - Hao Chen
  - Jessica A. Regan
  - Yulia Lipovka
  - S. Lahtinen
  - Lotta Stenman
  - Thuy-Vi V. Nguyen
  - Kristian P. Doyle
  - Marvin J. Slepian
  - Zain I Khalpey
  - J. Konhilas
- PubMed: 28409534
- DOI: 10.3920/BM2016.0119
5 Insights on
- Low evidence
- Animal Study
Assessment of the synbiotic properites of human milk oligosaccharides and Bifidobacterium longum subsp. infantis in vitro and in humanised mice.
- 2017-04-26
- Beneficial Microbes 8(2)
- - Š. Musilová
  - Nikol Modrackova
  - P. Hermanová
  - Tomas Hudcovic
  - R. Svejstil
  - Vojtech Rada
  - V. Tejnecký
  - V. Bunesova
- PubMed: 28116928
- DOI: 10.3920/BM2016.0138
5 Insights on
- Low evidence
Effect of a probiotic beverage consumption (Enterococcus faecium CRL 183 and Bifidobacterium longum ATCC 15707) in rats with chemically induced colitis
- 2017-04-24
- RCT · n = 5
- PLOS ONE 12(4)
- - L. Celiberto
  - R. Bedani
  - N. Dejani
  - Alexandra Ivo de Medeiros
  - José Antonio Sampaio Zuanon
  - L. C. Spolidorio
  - Maria Angela Tallarico Adorno
  - Maria Bernadete Amâncio Varesche
  - Fábio Carrilho Galvão
  - S. Valentini
  - G. Font de Valdez
  - E. Rossi
  - D. Cavallini
- PubMed: 28437455
- DOI: 10.1371/journal.pone.0175935
4 Insights on
- Low evidence
- Rigorous Journal
- Animal Study
Identification of proteins involved in the anti-inflammatory properties of Propionibacterium freudenreichii by means of a multi-strain study
- 2017-04-13
- Scientific Reports 7(1)
- - S. Deutsch
  - M. Mariadassou
  - P. Nicolas
  - S. Parayre
  - Rozenn Le Guellec
  - Victoria Chuat
  - V. Péton
  - C. Le Maréchal
  - J. Burati
  - V. Loux
  - V. Briard-Bion
  - J. Jardin
  - C. Ple
  - B. Foligné
  - G. Jan
  - H. Falentin
- PubMed: 28406170
- DOI: 10.1038/srep46409
1 Insight on
- Reduced Inflammation
- Low evidence
Evaluation of the Probiotic Strain Bifidobacterium longum subsp. Infantis CECT 7210 Capacities to Improve Health Status and Fight Digestive Pathogens in a Piglet Model
- 2017-04-11
- Clinical Trial · n = 72
- Frontiers in Microbiology 8
- - Emili Barba-Vidal
  - L. Castillejos
  - Paola López-Colom
  - M. Rivero Urgell
  - J. A. Moreno Muñoz
  - S. Martín-Orúe
- PubMed: 28443068
- DOI: 10.3389/fmicb.2017.00533
6 Insights on
- Low evidence
- Animal Study
Effect of combined consumption of Lactobacillus brevis KB290 and β-carotene on minor diarrhoea-predominant irritable bowel syndrome-like symptoms in healthy subjects: a randomised, double-blind, placebo-controlled, parallel-group trial.
- 2017-04-09
- RCT
- International journal of food sciences and nutrition 68(8)
- - Nobuo Fuke
  - Koichi Aizawa
  - Hiroyuki Suganuma
  - Tomohisa Takagi
  - Yuji Naito
- PubMed: 28391736
- DOI: 10.1080/09637486.2017.1311843
3 Insights on
- High evidence
Total Phenolic Content and Antioxidant Activity of Mycelial Extracts from the Medicinal Fungus Paecilomyces hepiali (Ascomycetes).
- 2017-04-07
- International Journal of Medicinal Mushrooms 19(1)
- - Lan Jiang
  - Yi Li
  - WEN-JING Wang
  - Abdessamad Imoulan
  - Yi‐Jian Yao
- PubMed: 28322145
- DOI: 10.1615/IntJMedMushrooms.v19.i1.40
1 Insight on
- Increased Antioxidant Activity
- Low evidence
Analyses of the probiotic property and stress resistance-related genes of Lactococcus lactis subsp. lactis NCDO 2118 through comparative genomics and in vitro assays
- 2017-04-06
- PLOS ONE 12(4)
- - L. C. Oliveira
  - T. Saraiva
  - W. M. Silva
  - U. Pereira
  - B. C. Campos
  - L. Benevides
  - F. Rocha
  - H. Figueiredo
  - V. Azevedo
  - S. Soares
- PubMed: 28384209
- DOI: 10.1371/journal.pone.0175116
1 Insight on
- Reduced Colitis Symptoms
- Low evidence
- Rigorous Journal
Selective method for identification and quantification of Bifidobacterium animalis subspecies lactis BB‐12 (BB‐12) from the gastrointestinal tract of healthy volunteers ingesting a combination probiotic of BB‐12 and Lactobacillus rhamnosus GG
- 2017-04-04
- Journal of Applied Microbiology 122(5)
- - D. Poutsiaka
  - I. J. Mahoney
  - L. McDermott
  - L. Stern
  - C. M. Thorpe
  - Anne Kane
  - C. Baez‐Giangreco
  - Julie M. McKINNEY
  - Lisa E. Davidson
  - Rina Leyva
  - Barry R. Goldin
  - D. R. Snydman
- PubMed: 28256070
- DOI: 10.1111/jam.13436
1 Insight on
- Viable Probiotic Strain Recovery
- Low evidence
Antimicrobial Compounds Produced by Vaginal Lactobacillus crispatus Are Able to Strongly Inhibit Candida albicans Growth, Hyphal Formation and Regulate Virulence-related Gene Expressions
- 2017-04-04
- Frontiers in Microbiology 8
- - Shuai Wang
  - Qiangyi Wang
  - E. Yang
  - Ling Yan
  - Tong Li
  - Zhuang Hui
- PubMed: 28421058
- DOI: 10.3389/fmicb.2017.00564
6 Insights on
- Low evidence
- Highly Cited
Fermented milk containing Lactobacillus paracasei subsp. paracasei CNCM I-1518 reduces bacterial translocation in rats treated with carbon tetrachloride
- 2017-04-03
- RCT
- Scientific Reports 7(1)
- - Elisabet Sánchez
  - J. C. Nieto
  - S. Vidal
  - A. Santiago
  - Xavier Martinez
  - F. Sancho
  - P. Sancho-Bru
  - B. Mirelis
  - H. Corominola
  - C. Juárez
  - C. Manichanh
  - C. Guarner
  - G. Soriano
- PubMed: 28368023
- DOI: 10.1038/srep45712
4 Insights on
- Low evidence
- Animal Study
Prospective study to compare antibiosis versus the association of N-acetylcysteine, D-mannose and Morinda citrifolia fruit extract in preventing urinary tract infections in patients submitted to urodynamic investigation.
- 2017-03-31
- RCT · n = 80
- Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica 89(1)
- - Giovanni Palleschi
  - Antonio Carbone
  - Pier Paolo Zanello
  - Rita Mele
  - Antonino Leto
  - Andrea Fuschi
  - Yazan Al Salhi
  - Gennaro Velotti
  - Samer Al Rawashdah
  - Gianluca Coppola
  - Angela Maurizi
  - Serena Maruccia
  - Antonio L Pastore
- PubMed: 28403598
- DOI: 10.4081/aiua.2017.1.45
1 Insight on
- Reduced Urinary Tract Infection
- High evidence
Early pregnancy probiotic supplementation with Lactobacillus rhamnosus HN001 may reduce the prevalence of gestational diabetes mellitus: a randomised controlled trial
- 2017-03-28
- RCT · n = 373
- British Journal of Nutrition 117(6)
- - K. Wickens
  - C. Barthow
  - R. Murphy
  - P. Abels
  - Robyn M. Maude
  - P. Stone
  - E. Mitchell
  - T. Stanley
  - G. Purdie
  - Janice Kang
  - Fiona Hood
  - Judy Rowden
  - Phillipa Barnes
  - P. Fitzharris
  - J. Crane
- PubMed: 28367765
- DOI: 10.1017/S0007114517000289
1 Insight on
- Reduced Prevalence of Gestational Diabetes Mellitus
- High evidence
- Large Human Trial
- Highly Cited
Oral administration of Bifidobacterium bifidum G9-1 alleviates rotavirus gastroenteritis through regulation of intestinal homeostasis by inducing mucosal protective factors
- 2017-03-27
- Clinical Trial
- PLOS ONE 12(3)
- - Tomohiro Kawahara
  - Yutaka Makizaki
  - Yosuke Oikawa
  - Yoshiki Tanaka
  - Ayako Maeda
  - M. Shimakawa
  - S. Komoto
  - Kyoko Moriguchi
  - H. Ohno
  - K. Taniguchi
- PubMed: 28346473
- DOI: 10.1371/journal.pone.0173979
7 Insights on
- Low evidence
- Rigorous Journal
- Animal Study
Enhanced Probiotic Potential of Lactobacillus reuteri When Delivered as a Biofilm on Dextranomer Microspheres That Contain Beneficial Cargo
- 2017-03-27
- Clinical Trial
- Frontiers in Microbiology 8
- - J. Navarro
  - L. Mashburn-Warren
  - L. Bakaletz
  - M. Bailey
  - S. Goodman
- PubMed: 28396655
- DOI: 10.3389/fmicb.2017.00489
6 Insights on
- Low evidence
- Animal Study
Vapor-fed bio-hybrid fuel cell.
- 2017-03-17
- Biotechnology for biofuels 10(1)
- - Marcus S Benyamin
  - Justin P Jahnke
  - David M Mackie
- PubMed: 28331544
- DOI: 10.1186/s13068-017-0755-7
2 Insights on
- Reduced Fossil Fuel Dependence
- Stable Long-Term Function
- Low evidence
Biochemical, physiological and clinical effects of l-methylfolate in schizophrenia: a randomized controlled trial.
- 2017-03-14
- RCT · n = 55
- Molecular psychiatry 23(2)
- - J L Roffman
  - L J Petruzzi
  - A S Tanner
  - H E Brown
  - H Eryilmaz
  - N F Ho
  - M Giegold
  - N J Silverstein
  - T Bottiglieri
  - D S Manoach
  - J W Smoller
  - D C Henderson
  - D C Goff
- PubMed: 28289280
- DOI: 10.1038/mp.2017.41
5 Insights on
- High evidence
Free-Radical Scavenging Activities of Cultured Mycelia of Paecilomyces hepiali (Ascomycetes) Extracts and Structural Characterization of Bioactive Components by Nuclear Magnetic Resonance Spectroscopy.
- 2017-03-07
- International Journal of Medicinal Mushrooms 18(10)
- - Lucia Ungvarska Mal'ucka
  - J. Harvanová
  - M. Pavlík
  - Martin Rajtar
  - Lukas Jarosciak
- PubMed: 27910757
- DOI: 10.1615/INTJMEDMUSHROOMS.V18.I10.50
1 Insight on
- Enhanced Antioxidant Activity
- Low evidence