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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Saccharomyces cerevisiae CNCM I-3856 in irritable bowel syndrome: An individual subject meta-analysis
- 2017-07-17
- Meta-Analysis
- World Journal of Gastroenterology 23(2)
- - Amélie Cayzeele-Decherf
  - Fanny Pélerin
  - S. Leuillet
  - Benoit Douillard
  - B. Housez
  - M. Cazaubiel
  - G. K. Jacobson
  - Peter Jüsten
  - P. Desreumaux
- PubMed: 28127207
- DOI: 10.3748/wjg.v23.i2.336
3 Insights on
- High evidence
- Rigorous Journal
Effect of Lactobacillus on body weight and body fat in overweight subjects: a systematic review of randomized controlled clinical trials
- 2017-07-10
- Systematic Review
- International Journal of Obesity 41(11)
- - Louise Crovesy
  - M. Ostrowski
  - D. M. Ferreira
  - E. L. Rosado
  - Marcia Soares-Mota
- PubMed: 28792488
- DOI: 10.1038/ijo.2017.161
2 Insights on
- Reduced Body Weight
- Reduced Body Fat
- High evidence
- Highly Cited
Antifungal Microbial Agents for Food Biopreservation-A Review.
- 2017-07-08
- Review
- Microorganisms 5(3)
- - Marcia Leyva Salas
  - Jérôme Mounier
  - Florence Valence
  - Monika Coton
  - Anne Thierry
  - Emmanuel Coton
- PubMed: 28698479
- DOI: 10.3390/microorganisms5030037
1 Insight on
- Reduced Fungal Load
- Moderate evidence
- Highly Cited
Influence of the Fruit Juice Carriers on the Ability of Lactobacillus plantarum DSM20205 to Improve in Vitro Intestinal Barrier Integrity and Its Probiotic Properties.
- 2017-07-05
- Journal of Agricultural and Food Chemistry 65(28)
- - E. Valero-Cases
  - N. Roy
  - M. Frutos
  - R. Anderson
- PubMed: 28627169
- DOI: 10.1021/acs.jafc.7b01551
1 Insight on
- Improved Intestinal Barrier Function
- Low evidence
Combined effect of Bacillus coagulans GBI-30, 6086 and HMB supplementation on muscle integrity and cytokine response during intense military training.
- 2017-07-01
- RCT · n = 26
- Journal of Applied Physiology 123(1)
- - Y. Gepner
  - J. Hoffman
  - E. Shemesh
  - Jeffrey R Stout
  - D. Church
  - Alyssa N. Varanoske
  - H. Zelicha
  - I. Shelef
  - Yacov Chen
  - H. Frankel
  - I. Ostfeld
- PubMed: 28408697
- DOI: 10.1152/japplphysiol.01116.2016
3 Insights on
- High evidence
Efficacy of a standardized extract of Matricariae chamomilla L., Melissa officinalis L. and tyndallized Lactobacillus acidophilus (HA122) in infantile colic: An open randomized controlled trial.
- 2017-06-30
- RCT · n = 60
- Neurogastroenterology and motility 29(12)
- - M Martinelli
  - D Ummarino
  - F P Giugliano
  - E Sciorio
  - C Tortora
  - D Bruzzese
  - D De Giovanni
  - I Rutigliano
  - S Valenti
  - C Romano
  - A Campanozzi
  - E Miele
  - A Staiano
- PubMed: 28665038
- DOI: 10.1111/nmo.13145
1 Insight on
- Reduced Crying Time
- High evidence
Effects of Bifidobacterium animalis subsp. lactis BB-12® on the lipid/lipoprotein profile and short chain fatty acids in healthy young adults: a randomized controlled trial
- 2017-06-29
- RCT · n = 30
- Nutrition Journal 16(1)
- - Yujin Lee
  - Zhaoyong Ba
  - R. Roberts
  - C. Rogers
  - J. Fleming
  - Huicui Meng
  - E. Furumoto
  - P. Kris-Etherton
- PubMed: 28662676
- DOI: 10.1186/s12937-017-0261-6
8 Insights on
- High evidence
Effects of the probiotic Bifidobacterium animalis subsp. lactis on the non-surgical treatment of periodontitis. A histomorphometric, microtomographic and immunohistochemical study in rats
- 2017-06-29
- RCT · n = 32
- PLOS ONE 12(6)
- - M. S. Ricoldi
  - F. Furlaneto
  - L. Oliveira
  - G. C. Teixeira
  - Jéssica P Pischiotini
  - A. L. Moreira
  - E. Ervolino
  - M. N. de Oliveira
  - C. Bogsan
  - S. Salvador
  - M. Messora
- PubMed: 28662142
- DOI: 10.1371/journal.pone.0179946
7 Insights on
- Low evidence
- Rigorous Journal
- Animal Study
Combination of Metabolomic and Proteomic Analysis Revealed Different Features among Lactobacillus delbrueckii Subspecies bulgaricus and lactis Strains While In Vivo Testing in the Model Organism Caenorhabditis elegans Highlighted Probiotic Properties
- 2017-06-28
- Frontiers in Microbiology 8
- - E. Zanni
  - Emily Schifano
  - S. Motta
  - F. Sciubba
  - C. Palleschi
  - P. Mauri
  - G. Perozzi
  - D. Uccelletti
  - C. Devirgiliis
  - A. Miccheli
- PubMed: 28702021
- DOI: 10.3389/fmicb.2017.01206
9 Insights on
- Low evidence
Preventive Effect of Lactobacillus helveticus SBT2171 on Collagen-Induced Arthritis in Mice
- 2017-06-21
- Clinical Trial
- Frontiers in Microbiology 8
- - M. Yamashita
  - K. Matsumoto
  - T. Endo
  - K. Ukibe
  - T. Hosoya
  - Y. Matsubara
  - H. Nakagawa
  - F. Sakai
  - T. Miyazaki
- PubMed: 28680422
- DOI: 10.3389/fmicb.2017.01159
10 Insights on
- Low evidence
- Animal Study
Phylogenomics and comparative genomics of Lactobacillus salivarius, a mammalian gut commensal
- 2017-06-13
- Microbial Genomics 3(8)
- - H. Harris
  - M. Bourin
  - M. Claesson
  - P. O’Toole
- PubMed: 29026656
- DOI: 10.1099/mgen.0.000115
2 Insights on
- Reduced Straining
- Potential Probiotic Health Effects
- Low evidence
- Rigorous Journal
High γ-aminobutyric acid production from lactic acid bacteria: Emphasis on Lactobacillus brevis as a functional dairy starter
- 2017-06-13
- Critical Reviews in Food Science and Nutrition 57(17)
- - Qinglong Wu
  - N. Shah
- PubMed: 26980301
- DOI: 10.1080/10408398.2016.1147418
3 Insights on
- Low evidence
- Highly Cited
Trans-Resveratrol Supplementation and Endothelial Function during the Fasting and Postprandial Phase: A Randomized Placebo-Controlled Trial in Overweight and Slightly Obese Participants.
- 2017-06-12
- RCT · n = 25
- Nutrients 9(6)
- - Sanne M van der Made
  - Jogchum Plat
  - Ronald P Mensink
- PubMed: 28604618
- DOI: 10.3390/nu9060596
5 Insights on
- High evidence
- Rigorous Journal
Lactobacillus johnsonii N6.2 Modulates the Host Immune Responses: A Double-Blind, Randomized Trial in Healthy Adults
- 2017-06-12
- RCT · n = 42
- Frontiers in Immunology 8
- - G. Marcial
  - A. Ford
  - M. Haller
  - S. Gezan
  - N. Harrison
  - D. Cai
  - Julie L. Meyer
  - D. Perry
  - M. Atkinson
  - C. Wasserfall
  - T. Garrett
  - Claudio F. Gonzalez
  - T. Brusko
  - W. Dahl
  - G. Lorca
- PubMed: 28659913
- DOI: 10.3389/fimmu.2017.00655
2 Insights on
- Reduced Kynurenine-Tryptophan Ratio
- Elevated Serum Tryptophan Levels
- High evidence
Live Probiotic Lactobacillus johnsonii BS15 Promotes Growth Performance and Lowers Fat Deposition by Improving Lipid Metabolism, Intestinal Development, and Gut Microflora in Broilers
- 2017-06-12
- RCT · n = 180
- Frontiers in Microbiology 8
- - Hesong Wang
  - Xueqin Ni
  - Xiaodan Qing
  - Dong Zeng
  - Min Luo
  - Lei Liu
  - Guangyao Li
  - Kangcheng Pan
  - Bo Jing
- PubMed: 28659893
- DOI: 10.3389/fmicb.2017.01073
9 Insights on
- Low evidence
- Highly Cited
- Animal Study
A synbiotic composed of Lactobacillus fermentum CECT5716 and FOS prevents the development of fatty acid liver and glycemic alterations in rats fed a high fructose diet associated with changes in the microbiota.
- 2017-06-08
- Clinical Trial
- Molecular Nutrition & Food Research 61(8)
- - Belén Rivero-Gutiérrez
  - Reyes Gámez-Belmonte
  - M. D. Suárez
  - J. Lavín
  - A. Aransay
  - M. Olivares
  - O. Martínez-Augustin
  - F. Sánchez de Medina
  - A. Zarzuelo
- PubMed: 28463404
- DOI: 10.1002/mnfr.201600622
7 Insights on
- Low evidence
- Animal Study
Effect of probiotic Lactobacillus on lipid profile: A systematic review and meta-analysis of randomized, controlled trials
- 2017-06-08
- Meta-Analysis
- PLOS ONE 12(6)
- - Yucheng Wu
  - Qingqing Zhang
  - Yin Ren
  - Z. Ruan
- PubMed: 28594860
- DOI: 10.1371/journal.pone.0178868
9 Insights on
- High evidence
- Highly Cited
- Rigorous Journal
Inorganic salts and intracellular polyphosphate inclusions play a role in the thermotolerance of the immunobiotic Lactobacillus rhamnosus CRL 1505
- 2017-06-08
- PLOS ONE 12(6)
- - M. A. Correa Deza
  - M. Grillo-Puertas
  - S. Salva
  - V. Rapisarda
  - C. L. Gerez
  - G. Font de Valdez
- PubMed: 28594955
- DOI: 10.1371/journal.pone.0179242
1 Insight on
- Improved Thermotolerance
- Low evidence
- Rigorous Journal
Enhancement of recovery from mental illness with l-methylfolate supplementation.
- 2017-06-08
- Review
- Perspectives in psychiatric care 54(2)
- - Gerald Martone
- PubMed: 28597528
- DOI: 10.1111/ppc.12227
3 Insights on
- Low evidence
Irritable bowel syndrome symptom severity improves equally with probiotic and placebo
- 2017-06-06
- RCT · n = 340
- World Journal of Gastroenterology 22(48)
- - Anna Lyra
  - M. Hillilä
  - T. Huttunen
  - Sofia Männikkö
  - M. Taalikka
  - Julia Tennilä
  - A. Tarpila
  - S. Lahtinen
  - A. Ouwehand
  - L. Veijola
- PubMed: 28082816
- DOI: 10.3748/wjg.v22.i48.10631
3 Insights on
- High evidence
- Large Human Trial
- Highly Cited
- Rigorous Journal
The regulation of immune cells by Lactobacilli: a potential therapeutic target for anti-atherosclerosis therapy.
- 2017-06-02
- Review
- Oncotarget 8(35)
- - Ya-Hui Ding
  - Lin-Yan Qian
  - Jie Pang
  - Jing-Yang Lin
  - Qiang Xu
  - Li-Hong Wang
  - Dong-Sheng Huang
  - Hai Zou
- PubMed: 28938693
- DOI: 10.18632/oncotarget.18346
2 Insights on
- Modulated Immune Response
- Reduced Inflammation
- Low evidence
Modulatory effects of l-carnitine plus l-acetyl-carnitine on neuroendocrine control of hypothalamic functions in functional hypothalamic amenorrhea (FHA).
- 2017-06-02
- Clinical Trial · n = 27
- Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 33(12)
- - Alessandro D Genazzani
  - Giulia Despini
  - Adam Czyzyk
  - Agnieszka Podfigurna
  - Tommaso Simoncini
  - Blazej Meczekalski
- PubMed: 28573875
- DOI: 10.1080/09513590.2017.1332587
4 Insights on
- Moderate evidence
Association of Dietary Vitamin K1 Intake With the Incidence of Cataract Surgery in an Adult Mediterranean Population: A Secondary Analysis of a Randomized Clinical Trial.
- 2017-06-01
- RCT · n = 5,860
- JAMA ophthalmology 135(6)
- - María L Camacho-Barcia
  - Mònica Bulló
  - Jesús F Garcia-Gavilán
  - Miguel Ruiz-Canela
  - Dolores Corella
  - Ramón Estruch
  - Montserrat Fitó
  - Alfredo García-Layana
  - Fernando Arós
  - Miquel Fiol
  - José Lapetra
  - Lluis Serra-Majem
  - Xavier Pintó
  - Ana García-Arellano
  - Ernest Vinyoles
  - José Vicente Sorli
  - Jordi Salas-Salvadó
- PubMed: 28494067
- DOI: 10.1001/jamaophthalmol.2017.1076
1 Insight on
- Reduced Cataract Incidence
- High evidence
- Large Human Trial
Consumption of Dairy Yogurt Containing Lactobacillus paracasei ssp. paracasei, Bifidobacterium animalis ssp. lactis and Heat-Treated Lactobacillus plantarum Improves Immune Function Including Natural Killer Cell Activity
- 2017-05-31
- RCT · n = 200
- Nutrients 9(6)
- - Ayoung Lee
  - Young Ju Lee
  - H. J. Yoo
  - Minkyung Kim
  - Yeeun Chang
  - Dong Seog Lee
  - J. H. Lee
- PubMed: 28561762
- DOI: 10.3390/nu9060558
14 Insights on
- High evidence
- Highly Cited
Safety and tolerability of Bifidobacterium longum subspecies infantis EVC001 supplementation in healthy term breastfed infants: a phase I clinical trial
- 2017-05-30
- BMC Pediatrics 17(1)
- - J. Smilowitz
  - Jackelyn Moya
  - Melissa A. Breck
  - Chelsea Cook
  - A. Fineberg
  - K. Angkustsiri
  - M. Underwood
- PubMed: 28558732
- DOI: 10.1186/s12887-017-0886-9
13 Insights on
- Low evidence
- Rigorous Journal
Exopolysaccharide-producing Streptococcus thermophilus CRL1190 reduces the inflammatory response caused by Helicobacter pylori.
- 2017-05-30
- Beneficial Microbes 8(3)
- - G. Marcial
  - J. Villena
  - G. Faller
  - A. Hensel
  - G. F. de Valdez
- PubMed: 28504579
- DOI: 10.3920/BM2016.0186
4 Insights on
- Low evidence
Lactobacillus rhamnosus CRL1505 nasal administration improves recovery of T-cell mediated immunity against pneumococcal infection in malnourished mice.
- 2017-05-30
- Clinical Trial
- Beneficial Microbes 8(3)
- - N. Barbieri
  - M. Herrera
  - S. Salva
  - J. Villena
  - S. Alvarez
- PubMed: 28504568
- DOI: 10.3920/BM2016.0152
4 Insights on
- Low evidence
- Animal Study
Bacillus coagulans GBI-30, 6086 increases plant protein digestion in a dynamic, computer-controlled in vitro model of the small intestine (TIM-1).
- 2017-05-30
- Beneficial Microbes 8(3)
- - D. Keller
  - R. V. Dinter
  - H. Cash
  - S. Farmer
  - Koen Venema
- PubMed: 28504581
- DOI: 10.3920/BM2016.0196
3 Insights on
- Low evidence
Prevent Effects of Lactobacillus Fermentum HY01 on Dextran Sulfate Sodium-Induced Colitis in Mice
- 2017-05-25
- Clinical Trial
- Nutrients 9(6)
- - Xiaoyong Chen
  - Xin Zhao
  - Hongwei Wang
  - Zelin Yang
  - Jian Li
  - Huayi Suo
- PubMed: 28587089
- DOI: 10.3390/nu9060545
4 Insights on
- Low evidence
- Highly Cited
- Animal Study
Lactobacillus rhamnosus HN001 and Lactobacillus acidophilus La-14 Attenuate Gardnerella vaginalis-Infected Bacterial Vaginosis in Mice
- 2017-05-23
- Clinical Trial
- Nutrients 9(6)
- - Se-Eun Jang
  - Jin-Ju Jeong
  - Su-Young Choi
  - Hyun-Jee Kim
  - M. Han
  - Dong-Hyun Kim
- PubMed: 28545241
- DOI: 10.3390/nu9060531
5 Insights on
- Low evidence
- Animal Study