Skip to main content

Evidence-Based Supplement Research

Evidence-Based Supplement Research

Supplement Research Feed

The latest peer-reviewed supplement and nutrition research, newest first — each study linked to the supplements and health outcomes it covers.

Nasally administered Lactobacillus rhamnosus accelerate the recovery of humoral immunity in B lymphocyte-deficient malnourished mice.
- 2013-02
- The Journal of Nutrition 143(2)
- - N. Barbieri
  - J. Villena
  - M. Herrera
  - S. Salva
  - S. Alvarez
- PubMed: 23269656
- DOI: 10.3945/jn.112.165811
12 Insights on
- Moderate evidence
Protective effects of probiotic Lactobacillus casei Zhang against endotoxin- and d-galactosamine-induced liver injury in rats via anti-oxidative and anti-inflammatory capacities.
- 2013-01
- Clinical Trial
- International Immunopharmacology 15(1)
- - Yuzhen Wang
  - Yunxu Li
  - Jiming Xie
  - Yong Zhang
  - Jinling Wang
  - Xiaolin Sun
  - Heping Zhang
- PubMed: 23146349
- DOI: 10.1016/j.intimp.2012.10.026
10 Insights on
- Low evidence
- Highly Cited
- Animal Study
Kefir and Health: A Contemporary Perspective
- 2013-01
- Review
- Critical Reviews in Food Science and Nutrition 53(5)
- - Zaheer Ahmed
  - Yanping Wang
  - Asif Ahmad
  - Salman Khan
  - M. Nisa
  - Hajra Ahmad
  - Asma Afreen
- PubMed: 23391011
- DOI: 10.1080/10408398.2010.540360
5 Insights on
- Moderate evidence
- Highly Cited
Transcriptional response of Lactobacillus acidophilus L-92 after attachment to epithelial Caco-2 cells.
- 2012-12
- Journal of Bioscience and Bioengineering 114(6)
- - S. Yanagihara
  - Tatsuhiko Hirota
  - N. Yamamoto
- PubMed: 22841868
- DOI: 10.1016/j.jbiosc.2012.07.001
1 Insight on
- Reduced Allergic Symptoms
- Low evidence
A preliminary, randomized, double-blind, placebo-controlled trial of L-carnosine to improve cognition in schizophrenia.
- 2012-12
- RCT
- Schizophrenia research 142(1-3)
- - K N Roy Chengappa
  - Scott R Turkin
  - Susan DeSanti
  - Christopher R Bowie
  - Jaspreet S Brar
  - Patricia J Schlicht
  - Sherry L Murphy
  - Michelle L Hetrick
  - Robert Bilder
  - David Fleet
- PubMed: 23099060
- DOI: 10.1016/j.schres.2012.10.001
10 Insights on
- High evidence
Lactococcus lactis subsp. cremoris FC triggers IFN-γ production from NK and T cells via IL-12 and IL-18.
- 2012-12
- Clinical Trial
- International Immunopharmacology 14(4)
- - A. Kosaka
  - Huimin Yan
  - S. Ohashi
  - Yayoi Gotoh
  - Ami Sato
  - H. Tsutsui
  - T. Kaisho
  - T. Toda
  - N. Tsuji
- PubMed: 23102661
- DOI: 10.1016/j.intimp.2012.10.007
8 Insights on
- Low evidence
- Animal Study
Probiotic Lactobacillus reuteri strains ATCC PTA 5289 and ATCC 55730 differ in their cariogenic properties in vitro.
- 2012-12
- Archives of Oral Biology 57(12)
- - Heli Jalasvuori
  - A. Haukioja
  - J. Tenovuo
- PubMed: 23010217
- DOI: 10.1016/j.archoralbio.2012.07.014
2 Insights on
- Improved Arginine Metabolism
- Decreased Hydroxyapatite Integrity
- Low evidence
Probiotics to adolescents with obesity: effects on inflammation and metabolic syndrome.
- 2012-12
- RCT
- Journal of pediatric gastroenterology and nutrition 55(6)
- - Rikke Juul Gøbel
  - Nadja Larsen
  - Mogens Jakobsen
  - Christian Mølgaard
  - Kim Fleischer Michaelsen
- PubMed: 22695039
- DOI: 10.1097/mpg.0b013e318263066c
16 Insights on
- High evidence
Developing oral probiotics from Streptococcus salivarius.
- 2012-12
- Future Microbiology 7(12)
- - P. Wescombe
  - J. Hale
  - N. Heng
  - J. Tagg
- PubMed: 23231486
- DOI: 10.2217/fmb.12.113
8 Insights on
- Low evidence
- Highly Cited
In vitro evaluation of the probiotic potential of Lactobacillus salivarius SMXD51.
- 2012-12
- Anaerobe 18(6)
- - Soumaya Messaoudi
  - Amar Madi
  - H. Prévost
  - M. Feuilloley
  - M. Manai
  - X. Dousset
  - N. Connil
- PubMed: 23122647
- DOI: 10.1016/j.anaerobe.2012.10.004
5 Insights on
- Low evidence
- Highly Cited
Protective effect of Bacillus subtilis ANSB060 on egg quality, biochemical and histopathological changes in layers exposed to aflatoxin B1.
- 2012-11
- Clinical Trial
- Poultry Science 91(11)
- - Q. Ma
  - X. Gao
  - T. Zhou
  - L. H. Zhao
  - Y. Fan
  - X. Y. Li
  - Y. Lei
  - C. Ji
  - J. Zhang
- PubMed: 23091142
- DOI: 10.3382/ps.2012-02474
3 Insights on
- Low evidence
- Rigorous Journal
- Animal Study
Dietary supplements for benign prostatic hyperplasia: an overview of systematic reviews.
- 2012-11
- Review
- Maturitas 73(3)
- - Tae-Hun Kim
  - Hyun-Ja Lim
  - Myung-Sunny Kim
  - Myeong Soo Lee
- PubMed: 22883375
- DOI: 10.1016/j.maturitas.2012.07.007
2 Insights on
- Improved Benign Prostatic Hyperplasia Symptoms
- Improved Urinary Flow Measure
- Low evidence
Substances released from probiotic Lactobacillus rhamnosus GR-1 potentiate NF-κB activity in Escherichia coli-stimulated urinary bladder cells.
- 2012-11
- FEMS Immunology & Medical Microbiology 66(2)
- - M. Karlsson
  - N. Scherbak
  - H. Khalaf
  - P. Olsson
  - J. Jass
- PubMed: 22620976
- DOI: 10.1111/j.1574-695X.2012.00994.x
1 Insight on
- Improved Immune Response
- Low evidence
Hypocholesterolaemic effect of yoghurt containing Bifidobacterium pseudocatenulatum G4 or Bifidobacterium longum BB536.
- 2012-11
- Food Chemistry 135(2)
- - S. Al-Sheraji
  - A. Ismail
  - M. Y. Manap
  - S. Mustafa
  - R. M. Yusof
  - F. Hassan
- PubMed: 22868099
- DOI: 10.1016/j.foodchem.2012.04.120
5 Insights on
- Low evidence
Yeasts in table olive processing: desirable or spoilage microorganisms?
- 2012-11
- International Journal of Food Microbiology 160(1)
- - F. N. Arroyo-López
  - V. Romero-Gil
  - J. Bautista-Gallego
  - F. Rodríguez-Gómez
  - R. Jiménez-Díaz
  - P. García-García
  - A. Querol
  - A. Garrido-Fernández
- PubMed: 23141644
- DOI: 10.1016/j.ijfoodmicro.2012.08.003
5 Insights on
- Low evidence
- Highly Cited
Potential role of probiotics on colorectal cancer prevention.
- 2012-11
- Review
- BMC surgery 12(S1)
- - Mario Uccello
  - Giulia Malaguarnera
  - Francesco Basile
  - Velia D'agata
  - Michele Malaguarnera
  - Gaetano Bertino
  - Marco Vacante
  - Filippo Drago
  - Antonio Biondi
- PubMed: 23173670
- DOI: 10.1186/1471-2482-12-s1-s35
1 Insight on
- Reduced Risk of Colorectal Cancer
- Moderate evidence
- Highly Cited
High-velocity intermittent running: effects of beta-alanine supplementation.
- 2012-10
- RCT · n = 26
- Journal of strength and conditioning research 26(10)
- - Abbie E Smith-Ryan
  - David H Fukuda
  - Jeffrey R Stout
  - Kristina L Kendall
  - Kristina L Kendall
- PubMed: 22797003
- DOI: 10.1519/jsc.0b013e318267922b
3 Insights on
- High evidence
Probiotics reduce gut microbial translocation and improve adult atopic dermatitis.
- 2012-10
- RCT
- Journal of clinical gastroenterology 46
- - Enrico Iemoli
  - Daria Trabattoni
  - Serena Parisotto
  - Linda Borgonovo
  - Marco Toscano
  - Giuliano Rizzardini
  - Mario Clerici
  - Elena Ricci
  - Alessandra Fusi
  - Elena De Vecchi
  - Stefania Piconi
  - Lorenzo Drago
- PubMed: 22955355
- DOI: 10.1097/mcg.0b013e31826a8468
6 Insights on
- High evidence
Bacillus coagulans GBI-30, 6086 limits the recurrence of Clostridium difficile-Induced colitis following vancomycin withdrawal in mice
- 2012-10
- Clinical Trial
- Gut Pathogens 4(1)
- - L. Fitzpatrick
  - Jeffrey S. Small
  - W. Greene
  - Kelly Karpa
  - S. Farmer
  - D. Keller
- PubMed: 23088680
- DOI: 10.1186/1757-4749-4-13
5 Insights on
- Low evidence
- Animal Study
Effects of dietary probiotic (Pediococcus acidilactici) supplementation on performance, nutrient digestibility, egg traits, egg yolk cholesterol, and fatty acid profile in laying hens.
- 2012-10
- RCT · n = 222
- Poultry Science 91(10)
- - D. Mikulski
  - J. Jankowski
  - Jakub Naczmański
  - M. Mikulska
  - V. Demey
- PubMed: 22991559
- DOI: 10.3382/PS.2012-02370
12 Insights on
- Low evidence
- Highly Cited
- Rigorous Journal
- Animal Study
Yogurt containing bioactive molecules produced by Lactobacillus acidophilus La-5 exerts a protective effect against enterohemorrhagic Escherichia coli in mice.
- 2012-10
- Clinical Trial
- Journal of Food Protection 75(10)
- - M. Zeinhom
  - M. Zeinhom
  - A. Tellez
  - V. Delcenserie
  - A. El-kholy
  - S. El-Shinawy
  - M. Griffiths
- PubMed: 23043828
- DOI: 10.4315/0362-028X.JFP-11-508
2 Insights on
- Reduced Severity of EHEC Infection
- Reduced Tumor Necrosis Factor Alpha Production
- Low evidence
- Animal Study
In vitro evaluation of Lactobacillus crispatus K313 and K243: high-adhesion activity and anti-inflammatory effect on Salmonella braenderup infected intestinal epithelial cell.
- 2012-09
- Veterinary Microbiology 159(1-2)
- - Zhilan Sun
  - Lihua Huang
  - J. Kong
  - Shumin Hu
  - Xiao-Wan Zhang
  - W. Kong
- PubMed: 22542524
- DOI: 10.1016/j.vetmic.2012.03.043
1 Insight on
- Reduced Inflammatory Response
- Low evidence
Fermented milk supplemented with probiotics and prebiotics can effectively alter the intestinal microbiota and immunity of host animals.
- 2012-09
- RCT · n = 100
- Journal of Dairy Science 95(9)
- - S. Wang
  - H. Zhu
  - C. Lu
  - Z. Kang
  - Y. Luo
  - L. Feng
  - X. Lu
- PubMed: 22916885
- DOI: 10.3168/jds.2012-5426
3 Insights on
- High evidence
- Highly Cited
Polypodium leucotomos extract in atopic dermatitis: a randomized, double-blind, placebo-controlled, multicenter trial.
- 2012-09
- RCT · n = 105
- Actas dermo-sifiliograficas 103(7)
- - A Ramírez-Bosca
  - P Zapater
  - I Betlloch
  - F Albero
  - A Martínez
  - J Díaz-Alperi
  - J F Horga
- PubMed: 22560125
- DOI: 10.1016/j.ad.2012.01.008
2 Insights on
- Reduced Topical Corticosteroid Use
- Reduced Oral Antihistamine Use
- High evidence
- Large Human Trial
Effects of probiotic, Clostridium butyricum, on growth performance, immune function, and cecal microflora in broiler chickens.
- 2012-09
- RCT · n = 450
- Poultry Science 91(9)
- - C. M. Yang
  - G. Cao
  - P. Ferket
  - Tao Liu
  - L. Zhou
  - L. Zhang
  - Y. Xiao
  - A. Chen
- PubMed: 22912445
- DOI: 10.3382/ps.2011-02131
3 Insights on
- Low evidence
- Highly Cited
- Rigorous Journal
- Animal Study
The effect of supplementation of flax-seed oil on interaction of Lactobacillus plantarum--Biocenol™ LP96 and Escherichia coli O8:K88ab:H9 in the gut of germ-free piglets.
- 2012-08
- Research in Veterinary Science 93(1)
- - R. Nemcová
  - D. Borovská
  - J. Koščová
  - S. Gancarčíková
  - D. Mudroňová
  - V. Buleca
  - J. Pistl
- PubMed: 21864874
- DOI: 10.1016/j.rvsc.2011.07.031
3 Insights on
- Low evidence
Antimicrobial activity of Streptococcus salivarius K12 on bacteria involved in oral malodour.
- 2012-08
- Archives of Oral Biology 57(8)
- - L. Masdea
  - E. Kulik
  - I. Hauser‐Gerspach
  - A. Ramseier
  - Andreas Filippi
  - T. Waltimo
- PubMed: 22405584
- DOI: 10.1016/j.archoralbio.2012.02.011
1 Insight on
- Reduced Oral Bacteria Growth
- Low evidence
- Highly Cited
Effect of supplementation of Bacillus subtilis LS 1-2 to broiler diets on growth performance, nutrient retention, caecal microbiology and small intestinal morphology.
- 2012-08
- RCT · n = 322
- Research in Veterinary Science 93(1)
- - Sinol Sen
  - S. Ingale
  - Y. W. Kim
  - J. S. Kim
  - K. H. Kim
  - J. Lohakare
  - E. K. Kim
  - H. Kim
  - M. Ryu
  - I. Kwon
  - B. Chae
- PubMed: 21757212
- DOI: 10.1016/j.rvsc.2011.05.021
4 Insights on
- Low evidence
- Highly Cited
- Animal Study
Comparative meta-analysis of the effect of Lactobacillus species on weight gain in humans and animals.
- 2012-08
- Meta-Analysis
- Microbial Pathogenesis 53(2)
- - M. Million
  - E. Angelakis
  - M. Paul
  - F. Armougom
  - L. Leibovici
  - D. Raoult
- PubMed: 22634320
- DOI: 10.1016/j.micpath.2012.05.007
1 Insight on
- Reduced Body Weight
- High evidence
- Highly Cited
Effects of a Lactobacillus salivarius probiotic intervention on infection, cold symptom duration and severity, and mucosal immunity in endurance athletes.
- 2012-08
- RCT · n = 66
- International Journal of Sport Nutrition and Exercise Metabolism 22(4)
- - M. Gleeson
  - N. Bishop
  - Marta Oliveira
  - T. McCauley
  - P. Tauler
  - C. Lawrence
- PubMed: 22645171
- DOI: 10.1123/IJSNEM.22.4.235
6 Insights on
- High evidence
- Highly Cited